Dietary fat intake predicts 1-year change in body fat in adolescent girls with type 1 diabetes.


OBJECTIVE:The purpose of this study was to determine whether objectively measured physical activity and dietary macronutrient intake differentially predict body fat in adolescent girls with type 1 diabetes and control girls. RESEARCH DESIGN AND METHODS:This study comprised 23 girls (12-19 years) with type 1 diabetes and 19 age-matched healthy control girls. At baseline, physical activity and energy intake were assessed for 7 consecutive days by accelerometry and a structured food diary, respectively. Body composition was measured by dual-energy X-ray absorptiometry at baseline and after 1 year. RESULTS:Fat intake was positively related to a 1-year change in percentage body fat (P = 0.006), after adjustment for total energy intake. No significant interaction was observed (case-control group x main exposure), indicating that the association between fat intake and gain in body fat was similar in both groups. Physical activity did not predict gain in body fat; however, total physical activity was positively associated with a gain in lean body mass (P < 0.01). Girls treated with six daily dosages of insulin increased their percentage of body fat significantly more than those treated with four daily injections (P < 0.05). CONCLUSIONS:In this prospective case-control study, we found that fat intake predicted gain in percentage of body fat in both adolescent girls with type 1 diabetes and healthy control girls. The number of daily insulin injections seems to influence the accumulation of body fat in girls with type 1 diabetes.


Diabetes Care


Diabetes care


Särnblad S,Ekelund U,Aman J




Has Abstract


2006-06-01 00:00:00














  • Psychosocial crisis in diabetic renal failure.

    abstract::Twenty-nine diabetic renal failure patients suffered a psychosocial crisis at the time when chronic dialysis or renal transplantation was required. These patients could be classified into groups as to the impact of the crisis in terms of participation in life-support therapy. Group 1 consisted of potentially lethal me...

    journal_title:Diabetes care

    pub_type: 杂志文章


    authors: D'Elia JA,Piening S,Kaldany A,Malarick C,Unger K,Ice S,Anderson RB,Miller DG,Lundin AP

    更新日期:1981-01-01 00:00:00

  • Detection of symptoms by adolescents and young adults with type 1 diabetes during experimental induction of mild hypoglycemia: role of hormonal and psychological variables.

    abstract:OBJECTIVE:To identify hormonal, psychological, and demographic predictors of symptom detection and accuracy of blood glucose estimation during mild hypoglycemia in adolescents and young adults with type 1 diabetes. RESEARCH DESIGN AND METHODS:During an insulin-glucose clamp study, 53 adolescents and 19 young adults es...

    journal_title:Diabetes care

    pub_type: 杂志文章


    authors: Ryan CM,Dulay D,Suprasongsin C,Becker DJ

    更新日期:2002-05-01 00:00:00

  • Plasma copeptin and renal outcomes in patients with type 2 diabetes and albuminuria.

    abstract:OBJECTIVE:Plasma copeptin, a surrogate for vasopressin, was associated with albuminuria in population-based studies. These associations are consistent with the effect of vasopressin on albuminuria observed in humans and rodents. The objective of this study was to determine whether plasma copeptin is an independent mark...

    journal_title:Diabetes care

    pub_type: 杂志文章


    authors: Velho G,Bouby N,Hadjadj S,Matallah N,Mohammedi K,Fumeron F,Potier L,Bellili-Munoz N,Taveau C,Alhenc-Gelas F,Bankir L,Marre M,Roussel R

    更新日期:2013-11-01 00:00:00

  • Glycosylated hemoglobin in relation to rapid fluctuations in blood glucose in children with insulin-dependent diabetes: a comparison of methods with and without prior dialysis.

    abstract::To evaluate the importance of dialysis in the determination of glycosylated hemoglobin (HbA1), we studied blood glucose and HbA1 in 38 insulin-dependent diabetic children during a morning fast and again 6 h postprandially. We used two methods to determine glycosylated hemoglobin: (1) the conventional macrocolumn metho...

    journal_title:Diabetes care

    pub_type: 杂志文章


    authors: Ditzel J,Kjaergaard JJ,Kawahara R,Ostergaard GZ,Mourits-Andersen T

    更新日期:1981-09-01 00:00:00

  • Topical phenytoin in diabetic foot ulcers.

    abstract:OBJECTIVE:The efficacy of topical phenytoin in the treatment of diabetic foot ulcers was evaluated in a controlled inpatient study. RESEARCH DESIGN AND METHODS:Fifty patients were treated with topical phenytoin, and 50 patients matched for age, sex, and ulcer areas, depth, chronicity, and infection were dressed with d...

    journal_title:Diabetes care

    pub_type: 临床试验,杂志文章


    authors: Muthukumarasamy MG,Sivakumar G,Manoharan G

    更新日期:1991-10-01 00:00:00

  • Evaluation of patient's knowledge of diabetes self-care.

    abstract::A survey conducted at a Veterans Administration Hospital to evaluate patient capability for self-management found that over 35 per cent of the patients interviewed lacked any formal training. Seventeen patients had been placed on insulin without formal instruction. Almost one half the patients who claimed to have atte...

    journal_title:Diabetes care

    pub_type: 杂志文章


    authors: Miller LV,Goldstein J,Nicolaisen G

    更新日期:1978-09-01 00:00:00

  • Clinical correlates of plantar pressure among diabetic veterans.

    abstract:OBJECTIVE:To assess the relationship between diabetes characteristics, medical history, foot deformity, sensory neuropathy, and plantar foot pressure. RESEARCH DESIGN AND METHODS:There were 517 subjects from a cohort of diabetic veterans enrolled in a prospective study of risk factors for foot complications who contri...

    journal_title:Diabetes care

    pub_type: 杂志文章


    authors: Ahroni JH,Boyko EJ,Forsberg RC

    更新日期:1999-06-01 00:00:00

  • Surveillance in Florida of continuous subcutaneous insulin infusion use in cohort.

    abstract::Because of concerns about safety and expense associated with continuous subcutaneous insulin infusion (CSII), all people who had used CSII as of July 1982 were identified. Annual follow-up has resulted in data for up to 61 mo. Of the 92 nonpregnant registrees, 31 were less than 20 yr old, 36 were 20-29, and 25 were 30...

    journal_title:Diabetes care

    pub_type: 杂志文章


    authors: Deeb LC,Williams PE

    更新日期:1986-11-01 00:00:00

  • Metabolite traits and genetic risk provide complementary information for the prediction of future type 2 diabetes.

    abstract:OBJECTIVE:A genetic risk score (GRS) comprised of single nucleotide polymorphisms (SNPs) and metabolite biomarkers have each been shown, separately, to predict incident type 2 diabetes. We tested whether genetic and metabolite markers provide complementary information for type 2 diabetes prediction and, together, impro...

    journal_title:Diabetes care

    pub_type: 杂志文章


    authors: Walford GA,Porneala BC,Dauriz M,Vassy JL,Cheng S,Rhee EP,Wang TJ,Meigs JB,Gerszten RE,Florez JC

    更新日期:2014-09-01 00:00:00

  • Survey of physician practice behaviors related to diabetes mellitus in the U.S. Physician adherence to consensus recommendations.

    abstract:OBJECTIVE:To summarize the frequency of physician adherence to consensus recommendations for prevention of diabetic complications. RESEARCH DESIGN AND METHODS:Survey data from a nationwide stratified probability sample of primary-care physicians were analyzed. Adherence to recommendations were reported by physician sp...

    journal_title:Diabetes care

    pub_type: 杂志文章


    authors: Kenny SJ,Smith PJ,Goldschmid MG,Newman JM,Herman WH

    更新日期:1993-11-01 00:00:00

  • Glycemic Outcomes of Use of CLC Versus PLGS in Type 1 Diabetes: A Randomized Controlled Trial.

    abstract:OBJECTIVE:Limited information is available about glycemic outcomes with a closed-loop control (CLC) system compared with a predictive low-glucose suspend (PLGS) system. RESEARCH DESIGN AND METHODS:After 6 months of use of a CLC system in a randomized trial, 109 participants with type 1 diabetes (age range, 14-72 years...

    journal_title:Diabetes care

    pub_type: 杂志文章


    authors: Brown SA,Beck RW,Raghinaru D,Buckingham BA,Laffel LM,Wadwa RP,Kudva YC,Levy CJ,Pinsker JE,Dassau E,Doyle FJ 3rd,Ambler-Osborn L,Anderson SM,Church MM,Ekhlaspour L,Forlenza GP,Levister C,Simha V,Breton MD,Kollman C,

    更新日期:2020-08-01 00:00:00

  • Reversion of β-Cell Autoimmunity Changes Risk of Type 1 Diabetes: TEDDY Study.

    abstract:OBJECTIVE:β-Cell autoantibodies are a feature of the preclinical phase of type 1 diabetes. Here, we asked how frequently they revert in a cohort of children at risk for type 1 diabetes and whether reversion has any effect on type 1 diabetes risk. RESEARCH DESIGN AND METHODS:Children were up to 10 years of age and scre...

    journal_title:Diabetes care

    pub_type: 杂志文章


    authors: Vehik K,Lynch KF,Schatz DA,Akolkar B,Hagopian W,Rewers M,She JX,Simell O,Toppari J,Ziegler AG,Lernmark Å,Bonifacio E,Krischer JP,TEDDY Study Group.

    更新日期:2016-09-01 00:00:00

  • Postural instability in patients with diabetic sensory neuropathy.

    abstract:OBJECTIVE:Recent survey evidence suggests that sensory ataxia due to diabetic neuropathy may be a more frequent and serious problem than is commonly recognized. This view is further supported by research that confirms the major contribution of the somatosensory system to the control of posture. We therefore sought to d...

    journal_title:Diabetes care

    pub_type: 杂志文章


    authors: Simoneau GG,Ulbrecht JS,Derr JA,Becker MB,Cavanagh PR

    更新日期:1994-12-01 00:00:00

  • Management of dyslipidemia in NIDDM.

    abstract::Coronary heart disease is the leading cause of death among patients with non-insulin-dependent diabetes mellitus (NIDDM). NIDDM patients have a high frequency of dyslipidemia, which along with obesity, hypertension, and hyperglycemia may contribute significantly to accelerated coronary atherosclerosis. Because risk fa...

    journal_title:Diabetes care

    pub_type: 杂志文章,评审


    authors: Garg A,Grundy SM

    更新日期:1990-02-01 00:00:00

  • Factors determining the blood pressure response to enalapril and nifedipine in hypertension associated with NIDDM.

    abstract:OBJECTIVE:To examine the factors that determine the blood pressure response to enalapril and nifedipine monotherapy in the treatment of hypertension associated with non-insulin-dependent diabetes mellitus (NIDDM). RESEARCH DESIGN AND METHODS:After a 6-week placebo baseline period, 102 hypertensive NIDDM patients were ...

    journal_title:Diabetes care

    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Chan JC,Nicholls MG,Cheung CK,Law LK,Swaminathan R,Cockram CS

    更新日期:1995-07-01 00:00:00

  • BMI versus the metabolic syndrome in relation to cardiovascular risk in elderly Chinese individuals.

    abstract:OBJECTIVE:The purpose of this study was to evaluate the associations of BMI versus metabolic syndrome with cardiovascular diseases (CVDs) in elderly Chinese individuals. RESEARCH DESIGN AND METHODS:We conducted a population-based cross-sectional study in an urban sample of 2,334 elderly subjects (943 men and 1,391 wom...

    journal_title:Diabetes care

    pub_type: 杂志文章,多中心研究


    authors: He Y,Jiang B,Wang J,Feng K,Chang Q,Zhu S,Fan L,Li X,Hu FB

    更新日期:2007-08-01 00:00:00

  • Sex differences in renal responses to hyperglycemia, L-arginine, and L-NMMA in humans with uncomplicated type 1 diabetes.

    abstract:OBJECTIVE:Women exhibit exaggerated renal hemodynamic responses to hyperglycemia, which may promote kidney disease progression. Our aim was to determine if increased nitric oxide generation by l-arginine infusion would reverse this deleterious response to clamped hyperglycemia in women with type 1 diabetes mellitus. R...

    journal_title:Diabetes care

    pub_type: 杂志文章


    authors: Cherney DZ,Scholey JW,Sochett EB

    更新日期:2013-05-01 00:00:00

  • Dyslipidemias among normoglycemic members of familial NIDDM pedigrees.

    abstract:OBJECTIVE:To examine the hypothesis that hyperinsulinemia among relatives of NIDDM probands will increase the prevalence of DLPs, we measured insulin levels and examined the frequency of DLPs among NIDDM pedigree members. RESEARCH DESIGN AND METHODS:We performed 2-h 75-g OGTTs and measured lipid and insulin levels of ...

    journal_title:Diabetes care

    pub_type: 杂志文章


    authors: Schumacher MC,Maxwell TM,Wu LL,Hunt SC,Williams RR,Elbein SC

    更新日期:1992-10-01 00:00:00

  • HOMA-estimated insulin resistance is an independent predictor of cardiovascular disease in type 2 diabetic subjects: prospective data from the Verona Diabetes Complications Study.

    abstract:OBJECTIVE:To evaluate whether homeostasis model assessment-estimated insulin resistance (HOMA-IR) is an independent predictor of cardiovascular disease (CVD) in type 2 diabetes. RESEARCH DESIGN AND METHODS:Conventional CVD risk factors (sex, age, smoking, plasma lipids, blood pressure, and metabolic control) and insul...

    journal_title:Diabetes care

    pub_type: 杂志文章,多中心研究


    authors: Bonora E,Formentini G,Calcaterra F,Lombardi S,Marini F,Zenari L,Saggiani F,Poli M,Perbellini S,Raffaelli A,Cacciatori V,Santi L,Targher G,Bonadonna R,Muggeo M

    更新日期:2002-07-01 00:00:00

  • Body fatness and fat distribution as predictors of metabolic abnormalities and early carotid atherosclerosis.

    abstract:OBJECTIVE:To test the hypothesis that intra-abdominal fat plays a primary role over general adiposity for metabolic abnormalities and atherosclerosis. RESEARCH DESIGN AND METHODS:We cross-sectionally studied 849 Japanese men aged 50.3 +/- 8.5 years (range 20-78) with BMI 23.5 +/- 2.9 kg/m(2). Intimal-medial thickness ...

    journal_title:Diabetes care

    pub_type: 杂志文章


    authors: Takami R,Takeda N,Hayashi M,Sasaki A,Kawachi S,Yoshino K,Takami K,Nakashima K,Akai A,Yamakita N,Yasuda K

    更新日期:2001-07-01 00:00:00

  • Analysis of Attained Height and Diabetes Among 554,122 Adults Across 25 Low- and Middle-Income Countries.

    abstract:OBJECTIVE:The prevalence of type 2 diabetes is rising rapidly in low-income and middle-income countries (LMICs), but the factors driving this rapid increase are not well understood. Adult height, in particular shorter height, has been suggested to contribute to the pathophysiology and epidemiology of diabetes and may i...

    journal_title:Diabetes care

    pub_type: 杂志文章


    authors: Teufel F,Geldsetzer P,Manne-Goehler J,Karlsson O,Koncz V,Deckert A,Theilmann M,Marcus ME,Ebert C,Seiglie JA,Agoudavi K,Andall-Brereton G,Gathecha G,Gurung MS,Guwatudde D,Houehanou C,Hwalla N,Kagaruki GB,Karki KB,Lab

    更新日期:2020-10-01 00:00:00

  • Markers of insulin resistance are strong risk factors for retinopathy incidence in type 1 diabetes.

    abstract:OBJECTIVE:To determine the incidence of retinopathy and the relative importance of its risk factors in type 1 diabetes. RESEARCH DESIGN AND METHODS:This is a 7.3-year follow-up of 764 of 1,215 (63%) people with type 1 diabetes across Europe, aged 15-60 years at baseline with no retinopathy (the EURODIAB Prospective Co...

    journal_title:Diabetes care

    pub_type: 杂志文章


    authors: Chaturvedi N,Sjoelie AK,Porta M,Aldington SJ,Fuller JH,Songini M,Kohner EM,EURODIAB Prospective Complications Study.

    更新日期:2001-02-01 00:00:00

  • Nonalcoholic fatty liver disease is a risk factor for type 2 diabetes in middle-aged Japanese men.

    abstract:OBJECTIVE:To determine the association between nonalcoholic fatty liver disease and the risk for development of diabetes. RESEARCH DESIGN AND METHODS:We conducted an observational cohort study in male workers > or = 40 years old in a Japanese company from 1997 to 2005. We excluded workers with alcohol intake > or = 20...

    journal_title:Diabetes care

    pub_type: 杂志文章


    authors: Shibata M,Kihara Y,Taguchi M,Tashiro M,Otsuki M

    更新日期:2007-11-01 00:00:00

  • Nocturnal cortisol release during hypoglycemia in diabetes.

    abstract::Nocturnal hypoglycemia in insulin-treated diabetic persons is often difficult to recognize clinically. It has been suggested that a useful biochemical test to demonstrate this would be the increased excretion of cortisol in the urine during the overnight period. However, of six diabetic persons who had nocturnal hypog...

    journal_title:Diabetes care

    pub_type: 杂志文章


    authors: Scott RS,Scandrett MS

    更新日期:1981-09-01 00:00:00

  • A model to determine workforce needs for endocrinologists in the United States until 2020.

    abstract::The objective of this study was to define the workforce needs for the specialty of Endocrinology, Diabetes, and Metabolism in the United States between 1999 and 2020. An interactive model of factors likely to influence the balance between the supply and demand of endocrinologists during the next 20 years was construct...

    journal_title:Diabetes care

    pub_type: 杂志文章


    authors: Rizza RA,Vigersky RA,Rodbard HW,Ladenson PW,Young WF Jr,Surks MI,Kahn R,Hogan PF

    更新日期:2003-05-01 00:00:00

  • Effect of treatment of gestational diabetes mellitus on obesity in the next generation.

    abstract:OBJECTIVE:Gestational diabetes mellitus (GDM) may cause obesity in the offspring. The objective was to assess the effect of treatment for mild GDM on the BMI of 4- to 5-year-old children. RESEARCH DESIGN AND METHODS:Participants were 199 mothers who participated in a randomized controlled trial of the treatment of mil...

    journal_title:Diabetes care

    pub_type: 杂志文章,随机对照试验


    authors: Gillman MW,Oakey H,Baghurst PA,Volkmer RE,Robinson JS,Crowther CA

    更新日期:2010-05-01 00:00:00

  • Islet cell antibody-positive versus -negative phenotypic type 2 diabetes in youth: does the oral glucose tolerance test distinguish between the two?

    abstract::OBJECTIVE Using the clamp technique, youths with a clinical diagnosis of type 2 diabetes (CDx-type 2 diabetes) and positive pancreatic autoantibodies (Ab(+)) were shown to have severe impairment in insulin secretion and less insulin resistance than their peers with negative antibodies (Ab(-)). In this study, we invest...

    journal_title:Diabetes care

    pub_type: 杂志文章


    authors: Tfayli H,Bacha F,Gungor N,Arslanian S

    更新日期:2010-03-01 00:00:00

  • Unrecognized diabetes among hospitalized patients.

    abstract:OBJECTIVE:To evaluate the hospital care rendered to hyperglycemic individuals who did not have a diagnosis of diabetes before admission. RESEARCH DESIGN AND METHODS:A total of 1,034 consecutively hospitalized adult patients at a 750-bed inner-city teaching hospital were evaluated. Patients with one or more plasma gluc...

    journal_title:Diabetes care

    pub_type: 杂志文章


    authors: Levetan CS,Passaro M,Jablonski K,Kass M,Ratner RE

    更新日期:1998-02-01 00:00:00

  • Effect of temperament on metabolic control in children with diabetes mellitus.

    abstract::Fifty-one children with insulin-dependent diabetes mellitus (IDDM) and 24 healthy sibling controls were compared on one of two temperament questionnaires completed by parents. Children with IDDM did not provide a characteristic temperament profile or show any problem areas. A regression analysis to predict diabetic co...

    journal_title:Diabetes care

    pub_type: 杂志文章


    authors: Rovet JF,Ehrlich RM

    更新日期:1988-01-01 00:00:00

  • Alanine aminotransferase and directly measured insulin sensitivity in a multiethnic cohort: the Insulin Resistance Atherosclerosis Study.

    abstract:OBJECTIVE:The objective of the present analysis was to evaluate the association of alanine aminotransferase (ALT) with directly measured insulin sensitivity (S(i)) in a large, multiethnic cohort of U.S. adults and to determine whether ALT adds to existing metabolic risk definitions in identifying subjects with insulin ...

    journal_title:Diabetes care

    pub_type: 杂志文章,多中心研究


    authors: Hanley AJ,Wagenknecht LE,Festa A,D'Agostino RB Jr,Haffner SM

    更新日期:2007-07-01 00:00:00