Normal glucose values are associated with a lower risk of mortality in hospitalized patients.

Abstract:

OBJECTIVE:Hyperglycemia is a common condition in hospitalized patients. The aim of this study was to investigate the relationships between glycemia upon admission and mortality in a heterogeneous group of adult patients. RESEARCH DESIGN AND METHODS:The 3-year records released from a general hospital were associated with a plasma glucose dataset of its general laboratory. A matched case-control study was implemented (3,338 case-control subject pairs). All-patient refined diagnosis-related groups and the relative risk of death were the matching criteria. A multivariate conditional logistic regression model was used to evaluate the associations between death and glycemia. RESULTS:Higher in-hospital mortality was associated with hyperglycemia or hypoglycemia, whereas lower risk was observed for values between 78 and 101 mg/dl. CONCLUSIONS:Our data confirm the relation between glycemia upon admission and mortality and suggest that slightly increased or decreased plasma glucose can be linked with increased mortality risk.

journal_name

Diabetes Care

journal_title

Diabetes care

authors

Bruno A,Gregori D,Caropreso A,Lazzarato F,Petrinco M,Pagano E

doi

10.2337/dc08-0672

subject

Has Abstract

pub_date

2008-11-01 00:00:00

pages

2209-10

issue

11

eissn

0149-5992

issn

1935-5548

pii

dc08-0672

journal_volume

31

pub_type

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    journal_title:Diabetes care

    pub_type: 杂志文章

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    journal_title:Diabetes care

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    pub_type: 临床试验,杂志文章,随机对照试验

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    pub_type: 临床试验,杂志文章,随机对照试验

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    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

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