Oral candidiasis in patients with diabetes mellitus: a thorough analysis.

Abstract:

:It has generally been assumed that oral candidiasis occurs with increased frequency in patients with diabetes mellitus. To evaluate this, we compared the frequency and severity of oral Candida colonization in 60 patients with insulin-dependent diabetes mellitus (IDDM) admitted to a low-intensity-care diabetes unit with those in 57 age- and sex-matched controls. Swabs taken from the tongue and buccal mucosa were examined by cytology rather than culture because of the discrimination provided by the former. Cytological smears were classified according to the presence and morphology of the Candida organisms. Overall, a significant difference in Candida species colonization was found between patients with diabetes (75.0%) and controls (35.1%) (P less than .005). In the diabetic group, no relationship was found to recent use of antibiotics, total or differential white blood cell count, serum glucose, presence of diabetic retinopathy, or glycosylated hemoglobin values. We conclude that in IDDM there is a predisposition to oral candidiasis and that this predisposition is independent of glucose control.

journal_name

Diabetes Care

journal_title

Diabetes care

authors

Bartholomew GA,Rodu B,Bell DS

doi

10.2337/diacare.10.5.607

subject

Has Abstract

pub_date

1987-09-01 00:00:00

pages

607-12

issue

5

eissn

0149-5992

issn

1935-5548

journal_volume

10

pub_type

杂志文章
  • Relationship Among Diabetes Distress, Decisional Conflict, Quality of Life, and Patient Perception of Chronic Illness Care in a Cohort of Patients With Type 2 Diabetes and Other Comorbidities.

    abstract:OBJECTIVE:The primary outcome is to evaluate the relationship between diabetes distress and decisional conflict regarding diabetes care in patients with diabetes and two or more comorbidities. Secondary outcomes include the relationships between diabetes distress and quality of life and patient perception of chronic il...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc18-1256

    authors: Bruno BA,Choi D,Thorpe KE,Yu CH

    更新日期:2019-07-01 00:00:00

  • Introducing the Endotype Concept to Address the Challenge of Disease Heterogeneity in Type 1 Diabetes.

    abstract::The clinical diagnosis of new-onset type 1 diabetes has, for many years, been considered relatively straightforward. Recently, however, there is increasing awareness that within this single clinical phenotype exists considerable heterogeneity: disease onset spans the complete age range; genetic susceptibility is compl...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc19-0880

    authors: Battaglia M,Ahmed S,Anderson MS,Atkinson MA,Becker D,Bingley PJ,Bosi E,Brusko TM,DiMeglio LA,Evans-Molina C,Gitelman SE,Greenbaum CJ,Gottlieb PA,Herold KC,Hessner MJ,Knip M,Jacobsen L,Krischer JP,Long SA,Lundgren M

    更新日期:2020-01-01 00:00:00

  • Sexual dysfunction in Jordanian diabetic women.

    abstract:OBJECTIVE:To estimate the prevalence of female sexual dysfunction (FSD) in diabetic and nondiabetic Jordanian women. RESEARCH DESIGN AND METHODS:Data were collected from 1,137 married women using the Arabic translation of the Female Sexual Function Index questionnaire. RESULTS:Prevalence of sexual dysfunction in diab...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc08-0081

    authors: Abu Ali RM,Al Hajeri RM,Khader YS,Shegem NS,Ajlouni KM

    更新日期:2008-08-01 00:00:00

  • Acute metabolic response to high-carbohydrate, high-starch meals compared with moderate-carbohydrate, low-starch meals in subjects with type 2 diabetes.

    abstract:OBJECTIVE:The monosaccharides resulting from the digestion of ingested carbohydrates are glucose, fructose, and galactose. Of these three monosaccharides, only ingested glucose resulted in a large increase in the plasma glucose concentration. Fructose (Metabolism 41:510-517, 1992) and galactose (Metabolism 42:1560-1567...

    journal_title:Diabetes care

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.2337/diacare.21.10.1619

    authors: Gannon MC,Nuttall FQ,Westphal SA,Fang S,Ercan-Fang N

    更新日期:1998-10-01 00:00:00

  • Remembering Statins: Do Statins Have Adverse Cognitive Effects?

    abstract::The issue of statin-associated cognitive impairment has been a hot topic among both patients and health care providers, especially since the U.S. Food and Drug Administration (FDA) issued a statement regarding rare postmarketing reports of ill-defined cognitive impairment associated with statin use. This statement was...

    journal_title:Diabetes care

    pub_type: 杂志文章,评审

    doi:10.2337/dcS15-3022

    authors: Bitzur R

    更新日期:2016-08-01 00:00:00

  • Peripheral Neuropathy and Nerve Dysfunction in Individuals at High Risk for Type 2 Diabetes: The PROMISE Cohort.

    abstract:OBJECTIVE:Emerging evidence suggests that peripheral neuropathy begins in the early stages of diabetes pathogenesis. Our objective was to describe the prevalence of peripheral neuropathy and nerve dysfunction according to glucose tolerance and metabolic syndrome status and examine how these conditions are associated wi...

    journal_title:Diabetes care

    pub_type: 杂志文章,多中心研究

    doi:10.2337/dc14-2585

    authors: Lee CC,Perkins BA,Kayaniyil S,Harris SB,Retnakaran R,Gerstein HC,Zinman B,Hanley AJ

    更新日期:2015-05-01 00:00:00

  • A pregnancy and postpartum lifestyle intervention in women with gestational diabetes mellitus reduces diabetes risk factors: a feasibility randomized control trial.

    abstract:OBJECTIVE:To pilot, among women with gestational diabetes mellitus (GDM), the feasibility of a prenatal/postpartum intervention to modify diet and physical activity similar to the Diabetes Prevention Program. The intervention was delivered by telephone, and support for breastfeeding was addressed. RESEARCH DESIGN AND ...

    journal_title:Diabetes care

    pub_type: 杂志文章,随机对照试验

    doi:10.2337/dc10-2221

    authors: Ferrara A,Hedderson MM,Albright CL,Ehrlich SF,Quesenberry CP Jr,Peng T,Feng J,Ching J,Crites Y

    更新日期:2011-07-01 00:00:00

  • Medical management of hyperglycemia in type 2 diabetes: a consensus algorithm for the initiation and adjustment of therapy: a consensus statement of the American Diabetes Association and the European Association for the Study of Diabetes.

    abstract::The consensus algorithm for the medical management of type 2 diabetes was published in August 2006 with the expectation that it would be updated, based on the availability of new interventions and new evidence to establish their clinical role. The authors continue to endorse the principles used to develop the algorith...

    journal_title:Diabetes care

    pub_type: 共识发展会议,杂志文章,实务指引

    doi:10.2337/dc08-9025

    authors: Nathan DM,Buse JB,Davidson MB,Ferrannini E,Holman RR,Sherwin R,Zinman B,American Diabetes Association.,European Association for Study of Diabetes.

    更新日期:2009-01-01 00:00:00

  • Predicting the development of diabetes in older adults: the derivation and validation of a prediction rule.

    abstract:OBJECTIVE:To create a simple prediction rule that could perform as well as the 2-h postchallenge plasma glucose (PCPG) test to predict those at risk for diabetes. We created a prediction rule in one sample and prospectively validated it for incident diabetes in a separate cohort. RESEARCH DESIGN AND METHODS:A cross-se...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.28.2.404

    authors: Kanaya AM,Wassel Fyr CL,de Rekeneire N,Shorr RI,Schwartz AV,Goodpaster BH,Newman AB,Harris T,Barrett-Connor E

    更新日期:2005-02-01 00:00:00

  • Impact of BMI and the metabolic syndrome on the risk of diabetes in middle-aged men.

    abstract:OBJECTIVE:The existence of an obese subgroup with a healthy metabolic profile and low diabetes risk has been proposed; yet long-term data are lacking. We aimed to investigate associations between combinations of BMI categories and metabolic syndrome and risk of type 2 diabetes in middle-aged men. RESEARCH DESIGN AND M...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc10-0955

    authors: Arnlöv J,Sundström J,Ingelsson E,Lind L

    更新日期:2011-01-01 00:00:00

  • Combined effect of nonalcoholic fatty liver disease and impaired fasting glucose on the development of type 2 diabetes: a 4-year retrospective longitudinal study.

    abstract:OBJECTIVE:To evaluate whether there is a difference in the association between nonalcoholic fatty liver disease (NAFLD) and incident diabetes based on the presence of impaired fasting glucose. RESEARCH DESIGN AND METHODS:A total of 7,849 individuals (5,409 men and 2,440 women) without diabetes, who underwent comprehen...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc10-1991

    authors: Bae JC,Rhee EJ,Lee WY,Park SE,Park CY,Oh KW,Park SW,Kim SW

    更新日期:2011-03-01 00:00:00

  • Patients With Diabetes Without Significant Angiographic Coronary Artery Disease Have the Same Risk of Myocardial Infarction as Patients Without Diabetes in a Real-World Population Receiving Appropriate Prophylactic Treatment.

    abstract:OBJECTIVE:The risk of myocardial infarction (MI) in patients with diabetes is greater than for patients without diabetes. Consequently, prophylactic treatment is recommended for patients with diabetes and risk factors for ischemic heart disease. We aimed to estimate the risk of adverse cardiac events in patients with a...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc16-2388

    authors: Olesen KKW,Madsen M,Egholm G,Thim T,Jensen LO,Raungaard B,Bøtker HE,Sørensen HT,Maeng M

    更新日期:2017-08-01 00:00:00

  • Frailty and Risk of Fractures in Patients With Type 2 Diabetes.

    abstract:OBJECTIVE:We aimed to explore whether frailty was associated with fracture risk and whether frailty could modify the propensity of type 2 diabetes toward increased risk of fractures. RESEARCH DESIGN AND METHODS:Data were from a prospective cohort study. Our primary outcome was time to the first incident clinical fragi...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc18-1965

    authors: Li G,Prior JC,Leslie WD,Thabane L,Papaioannou A,Josse RG,Kaiser SM,Kovacs CS,Anastassiades T,Towheed T,Davison KS,Levine M,Goltzman D,Adachi JD,CaMos Research Group.

    更新日期:2019-04-01 00:00:00

  • Serum Galectin-3 and Subsequent Risk of Coronary Heart Disease in Subjects With Childhood-Onset Type 1 Diabetes: A Cohort Study.

    abstract:OBJECTIVE:To study whether serum galectin-3 and other biomarkers of inflammation predict coronary heart disease (CHD) in subjects with long-standing childhood-onset type 1 diabetes. RESEARCH DESIGN AND METHODS:A population-based nationwide cohort of 299 subjects with type 1 diabetes diagnosed in Norway at <15 years of...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc20-1712

    authors: Saeed M,Tapia G,Ariansen I,Stene LC,Seljeflot I,Tell GS,Skrivarhaug T,Joner G

    更新日期:2021-01-06 00:00:00

  • The association between different A1C-based measures of glycemia and risk of cardiovascular disease hospitalization.

    abstract::OBJECTIVE We tested whether average monthly glycemic burden (AMGB), a marker of hyperglycemia that is a function of the extent and duration that A1C exceeded 7%, indicated greater risk of cardiovascular disease (CVD) than traditional A1C measures. RESEARCH DESIGN AND METHODS Using a case-control design, we studied 2,4...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc13-1300

    authors: Nichols GA,Rosales AG,Perrin NA,Fortmann SP

    更新日期:2014-01-01 00:00:00

  • Metabolic Syndrome Components Are Associated With Symptomatic Polyneuropathy Independent of Glycemic Status.

    abstract:OBJECTIVE:Previous studies demonstrate that the metabolic syndrome is associated with distal symmetric polyneuropathy (DSP). We aimed to determine the magnitude of this effect and the precise components involved. RESEARCH DESIGN AND METHODS:We determined the symptomatic DSP prevalence in the Health, Aging, and Body Co...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc16-0081

    authors: Callaghan BC,Xia R,Banerjee M,de Rekeneire N,Harris TB,Newman AB,Satterfield S,Schwartz AV,Vinik AI,Feldman EL,Strotmeyer ES,Health ABC Study.

    更新日期:2016-05-01 00:00:00

  • Controversies for Glucose Control Targets in Type 2 Diabetes: Exposing the Common Ground.

    abstract::Glycated hemoglobin targets have been given in guidelines for the last three decades, mostly without change at around 6.5-7.0% (47-53 mmol/mol). Personalization of such targets has also long been advocated, but often with little and inappropriate guidance. More recently some have suggested higher targets might be indi...

    journal_title:Diabetes care

    pub_type: 杂志文章,评审

    doi:10.2337/dci19-0002

    authors: Home P

    更新日期:2019-09-01 00:00:00

  • Clinical impact of prandial state, exercise, and site preparation on the equivalence of alternative-site blood glucose testing.

    abstract:OBJECTIVE:To determine whether clinically significant differences exist in fasting blood glucose (BG) at the forearm, palm, and thigh relative to the fingertip; to assess the impact of prandial status by comparing BG between alternative sites and the fingertip at several time intervals after carbohydrate intake; to ass...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.26.4.981

    authors: Bina DM,Anderson RL,Johnson ML,Bergenstal RM,Kendall DM

    更新日期:2003-04-01 00:00:00

  • Defining Abdominal Obesity as a Risk Factor for Coronary Heart Disease in the U.S.: Results From the Hispanic Community Health Study/Study of Latinos (HCHS/SOL).

    abstract:OBJECTIVE:Various organizations have highlighted the need to examine whether abdominal obesity cut points are appropriate for identification of cardiovascular risk among ethnic minority adults, particularly Hispanic/Latino adults living in Western societies. This study aimed 1) to establish optimal definitions for abdo...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc19-1855

    authors: Chirinos DA,Llabre MM,Goldberg R,Gellman M,Mendez A,Cai J,Sotres-Alvarez D,Daviglus M,Gallo LC,Schneiderman N

    更新日期:2020-08-01 00:00:00

  • Injection site effects on the pharmacokinetics and glucodynamics of insulin lispro and regular insulin.

    abstract:OBJECTIVE:The pharmacokinetics and glucodynamics of a new insulin analog, insulin lispro, and regular human insulin were compared and contrasted after subcutaneous administrations in femoral, deltoid, and abdominal injection sites. RESEARCH DESIGN AND METHODS:Single 0.2 U/kg doses of insulin lispro and regular insulin...

    journal_title:Diabetes care

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.2337/diacare.19.12.1437

    authors: ter Braak EW,Woodworth JR,Bianchi R,Cerimele B,Erkelens DW,Thijssen JH,Kurtz D

    更新日期:1996-12-01 00:00:00

  • Asian Americans: diabetes prevalence across U.S. and World Health Organization weight classifications.

    abstract:OBJECTIVE:To compare diabetes prevalence among Asian Americans by World Health Organization and U.S. BMI classifications. RESEARCH DESIGN AND METHODS:Data on Asian American adults (n = 7,414) from the National Health Interview Survey for 1997-2005 were analyzed. Diabetes prevalence was estimated across weight and ethn...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc09-0573

    authors: Oza-Frank R,Ali MK,Vaccarino V,Narayan KM

    更新日期:2009-09-01 00:00:00

  • Metabolite traits and genetic risk provide complementary information for the prediction of future type 2 diabetes.

    abstract:OBJECTIVE:A genetic risk score (GRS) comprised of single nucleotide polymorphisms (SNPs) and metabolite biomarkers have each been shown, separately, to predict incident type 2 diabetes. We tested whether genetic and metabolite markers provide complementary information for type 2 diabetes prediction and, together, impro...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc14-0560

    authors: Walford GA,Porneala BC,Dauriz M,Vassy JL,Cheng S,Rhee EP,Wang TJ,Meigs JB,Gerszten RE,Florez JC

    更新日期:2014-09-01 00:00:00

  • The effect of oral antidiabetic agents on A1C levels: a systematic review and meta-analysis.

    abstract:OBJECTIVE:Previous reviews of the effect of oral antidiabetic (OAD) agents on A1C levels summarized studies with varying designs and methodological approaches. Using predetermined methodological criteria, we evaluated the effect of OAD agents on A1C levels. RESEARCH DESIGN AND METHODS:The Excerpta Medica (EMBASE), the...

    journal_title:Diabetes care

    pub_type: 杂志文章,meta分析,评审

    doi:10.2337/dc09-1727

    authors: Sherifali D,Nerenberg K,Pullenayegum E,Cheng JE,Gerstein HC

    更新日期:2010-08-01 00:00:00

  • Elevated TyG Index Predicts Progression of Coronary Artery Calcification.

    abstract:OBJECTIVE:To investigate the triglyceride-glucose (TyG) index association with coronary artery calcification (CAC) progression in adult Koreans. RESEARCH DESIGN AND METHODS:Various cardiovascular risk factors and anthropometric profiles were assessed in 1,175 subjects who previously had a CAC evaluation at least twice...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc18-1920

    authors: Park K,Ahn CW,Lee SB,Kang S,Nam JS,Lee BK,Kim JH,Park JS

    更新日期:2019-08-01 00:00:00

  • Exogenous estrogen exposures and changes in diabetic retinopathy. The Wisconsin Epidemiologic Study of Diabetic Retinopathy.

    abstract:OBJECTIVE:To investigate whether the use of exogenous estrogen is associated with changes in the severity of diabetic retinopathy and the incidence of macular edema. RESEARCH DESIGN AND METHODS:The study design involved observation of two well-defined cohorts of women with diabetes. One group was diagnosed with diabet...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.22.12.1984

    authors: Klein BE,Klein R,Moss SE

    更新日期:1999-12-01 00:00:00

  • Is type 2 diabetes a different disease in obese and nonobese patients?

    abstract:OBJECTIVE:The main purpose of this work was to study the possible differences in insulin secretion in a large group of type 2 diabetic patients in relation to diabetes duration, obesity, and the presence of secondary failure after treatment with oral hypoglycemic agents. RESEARCH DESIGN AND METHODS:There were 147 nono...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.21.10.1680

    authors: Prando R,Cheli V,Melga P,Giusti R,Ciuchi E,Odetti P

    更新日期:1998-10-01 00:00:00

  • Acute complications and drug misuse are important causes of death for children and young adults with type 1 diabetes: results from the Yorkshire Register of diabetes in children and young adults.

    abstract:OBJECTIVE:To examine mortality rates and causes of death among subjects diagnosed with type 1 diabetes aged

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc07-2029

    authors: Feltbower RG,Bodansky HJ,Patterson CC,Parslow RC,Stephenson CR,Reynolds C,McKinney PA

    更新日期:2008-05-01 00:00:00

  • Bimodal distribution of glucose is not universally useful for diagnosing diabetes.

    abstract:OBJECTIVE:Bimodality in the distribution of glucose has been used to define the cut point for the diagnosis of diabetes. Previous studies on bimodality have primarily been in populations with a high prevalence of type 2 diabetes, including one study in a white Caucasian population. All studies included participants wit...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc08-0867

    authors: Vistisen D,Colagiuri S,Borch-Johnsen K,DETECT-2 Collaboration.

    更新日期:2009-03-01 00:00:00

  • HLA-DQ beta typing and non-Asp57 alleles in IDDM and nondiabetic subjects in New Zealand.

    abstract:OBJECTIVE:To determine the frequency of IDDM risk-associated HLA-DQ beta alleles in New Zealanders with IDDM and nondiabetic control subjects, and to examine these as susceptibility markers in relation to IDDM incidence. RESEARCH DESIGN AND METHODS:HLA-DQ beta typing was conducted in 55 juvenile-onset IDDM subjects di...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.16.8.1179

    authors: Forbes LV,Brown LJ,Scott RS

    更新日期:1993-08-01 00:00:00

  • Low prevalence of islet autoantibodies in patients with gestational diabetes mellitus.

    abstract:OBJECTIVE:To determine the proportion of patients with gestational diabetes mellitus (GDM) who have serological characteristics typical of IDDM. RESEARCH DESIGN AND METHODS:Islet cell antibodies (ICAs), insulin autoantibodies (IAAs), GAD65, and IA-2 antibodies were measured in 145 pregnant women with GDM, 33 with impa...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.20.1.81

    authors: Dozio N,Beretta A,Belloni C,Castiglioni M,Rosa S,Bosi E,Bonifacio E

    更新日期:1997-01-01 00:00:00