Abstract:
OBJECTIVE:Various organizations have highlighted the need to examine whether abdominal obesity cut points are appropriate for identification of cardiovascular risk among ethnic minority adults, particularly Hispanic/Latino adults living in Western societies. This study aimed 1) to establish optimal definitions for abdominal obesity among Hispanics/Latinos and 2) to determine the level of agreement between the presence of metabolic syndrome diagnosed by the current Joint Interim Statement (JIS) definition and an updated definition with optimal abdominal obesity cut points. RESEARCH DESIGN AND METHODS:The sample included 16,289 adults who self-identified as Hispanic/Latino ages 18-74 years enrolled in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL). Receiver operating characteristic curves were used to derive sensitivity and specificity values. The largest sum of sensitivity plus specificity was used to determine appropriate cut points. RESULTS:Among U.S. Hispanic/Latino adults, waist circumference cut points of >102 cm in men (in line with current JIS criteria) and >97 cm (9 points higher than JIS criteria) in women provide optimal discrimination for cardiovascular risk as judged by the presence of coronary heart disease. When using these cut points to create an updated metabolic syndrome definition among women, we found disagreement between our updated definition and the current JIS criteria. The prevalence of the metabolic syndrome was overestimated by ∼5 percentage points among women based on JIS criteria in comparison with our definition. CONCLUSIONS:Our results suggest that the current recommendations for waist circumference cut points may not be appropriate for U.S. Hispanic/Latino women.
journal_name
Diabetes Carejournal_title
Diabetes careauthors
Chirinos DA,Llabre MM,Goldberg R,Gellman M,Mendez A,Cai J,Sotres-Alvarez D,Daviglus M,Gallo LC,Schneiderman Ndoi
10.2337/dc19-1855subject
Has Abstractpub_date
2020-08-01 00:00:00pages
1774-1780issue
8eissn
0149-5992issn
1935-5548pii
dc19-1855journal_volume
43pub_type
杂志文章相关文献
DIABETES CARE文献大全abstract:OBJECTIVE:Because the bovine serum albumin residues 126-144 (ABBOS) have been reported to be responsible for the autoimmune reaction directed against pancreatic islet cells, it was our aim to study the potential survival of the ABBOS epitope during digestion in the gastrointestinal tract. RESEARCH DESIGN AND METHODS:E...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/diacare.20.5.875
更新日期:1997-05-01 00:00:00
abstract:OBJECTIVE:To compare albumin-to-creatinine ratio (ACR) and albumin concentration (ALB) for detection of microalbuminuria using precise data on CIs for sensitivity and specificity and to determine sex- and age-specific discriminator values for ACR. RESEARCH DESIGN AND METHODS:All consecutive patients investigated for t...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/diacare.22.2.307
更新日期:1999-02-01 00:00:00
abstract:OBJECTIVE:Recent studies show the importance of controlling blood glucose variability in relationship to both reducing hypoglycemia and attenuating the risk for cardiovascular and behavioral complications due to hyperglycemia. It is therefore important to design variability measures that are equally predictive of low a...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/dc06-1085
更新日期:2006-11-01 00:00:00
abstract:OBJECTIVE:To investigate the relationship between lifestyle counseling in primary care settings and clinical outcomes in patients with diabetes. RESEARCH DESIGN AND METHODS:We retrospectively studied hyperglycemic adults with diabetes treated at primary care practices between 2000 and 2014. We analyzed the relationshi...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/dc19-0629
更新日期:2019-09-01 00:00:00
abstract:OBJECTIVE:To examine patients' views of the acceptability of and satisfaction with telephone care center support provided to improve blood glucose control in type 2 diabetes. RESEARCH DESIGN AND METHODS:The Pro-Active Call-Center Treatment Support (PACCTS) Trial randomized patients from 47 general practices in a depri...
journal_title:Diabetes care
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.2337/diacare.28.2.283
更新日期:2005-02-01 00:00:00
abstract:OBJECTIVE:To determine the impact of chronic exercise training initiated later in life upon development of metabolic markers of cardiovascular disease risk. RESEARCH DESIGN AND METHODS:Two inception cohorts of previously sedentary healthy adults aged 55-75 years at baseline (1989), one initiating regular supervised ph...
journal_title:Diabetes care
pub_type: 临床试验,杂志文章
doi:10.2337/diacare.28.3.694
更新日期:2005-03-01 00:00:00
abstract:OBJECTIVE:We aimed to update the epidemiology of type 1 and type 2 diabetic patients among the incident end-stage renal disease (ESRD) population in Australia and New Zealand (ANZ) and to determine whether outcome is worse for diabetic women, as described in the general population. RESEARCH DESIGNS AND METHODS:All res...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/dc07-0895
更新日期:2007-12-01 00:00:00
abstract:OBJECTIVE:To investigate the effects of fenofibrate and coenzyme Q(10) (CoQ) on diastolic function, ambulatory blood pressure (ABP), and heart rate (HR) in type 2 diabetic subjects with left ventricular diastolic dysfunction (LVDD). RESEARCH DESIGN AND METHODS:We randomized, double-blind, 74 subjects to fenofibrate 16...
journal_title:Diabetes care
pub_type: 杂志文章,随机对照试验
doi:10.2337/dc08-0118
更新日期:2008-08-01 00:00:00
abstract:OBJECTIVE:The purpose of this paper is to estimate the impact of diabetes on survival among patients with first acute myocardial infarction, using data from the World Health Organization (WHO) Monitoring Trends and Determinants of Cardiovascular Disease (MONICA) Project in Newcastle, New South Wales, Australia. RESEAR...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/diacare.20.5.704
更新日期:1997-05-01 00:00:00
abstract::We studied the accuracy of the Chemstrip bG and Glucometer systems in the self-monitoring of blood glucose by trained adolescents. The determinations were done at home with simultaneous collection of whole blood into capillary tubes (Sarstedt) which were later analyzed by a glucose-oxidase analyzer (Beckman Instrument...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/diacare.6.2.166
更新日期:1983-03-01 00:00:00
abstract:OBJECTIVE:We sought to test the hypothesis that start of insulin glargine with sustained nightly insulin action results in changes in circulating concentrations of IGF-I and IGF binding proteins (IGFBPs) in adolescents with type 1 diabetes-changes that may support improvement of A1C. RESEARCH DESIGN AND METHODS:Twelve...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/dc06-2328
更新日期:2007-06-01 00:00:00
abstract::OBJECTIVE To assess vital signs, QT intervals, and newly diagnosed cardiovascular disease during severe hypoglycemia in diabetic patients. RESEARCH DESIGN AND METHODS From January 2006 to March 2012, we conducted a retrospective cohort study to assess type 1 and type 2 diabetic patients with severe hypoglycemia at a n...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/dc13-0701
更新日期:2014-01-01 00:00:00
abstract:OBJECTIVE:To analyze safety and efficacy of the Diabeloop Generation 1 (DBLG1) hybrid closed-loop artificial pancreas system in patients with type 1 diabetes in real-world conditions. RESEARCH DESIGN AND METHODS:After a 1-week run-in period with their usual pump, 25 patients were provided the commercial DBLG1 system. ...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/dc20-1809
更新日期:2021-01-11 00:00:00
abstract:OBJECTIVE:Cases of acute pancreatitis have been reported in association with exenatide, sitagliptin, and type 2 diabetes without use of these medications. It remains unknown whether exenatide or sitagliptin increase the risk of acute pancreatitis. RESEARCH DESIGN AND METHODS:A retrospective cohort study of a large med...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/dc10-0482
更新日期:2010-11-01 00:00:00
abstract:OBJECTIVE:We assessed the association between different blood lipid measures and risk of fatal/nonfatal coronary heart disease (CHD). RESEARCH DESIGN AND METHODS:We conducted an observational study of patients with type 2 diabetes from the Swedish National Diabetes Register. Baseline LDL cholesterol, non-HDL cholester...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/dc11-0209
更新日期:2011-09-01 00:00:00
abstract:OBJECTIVE:To compare the health service utilization and long-term outcomes of acute myocardial infarction (AMI) patients with and without diabetes in Ontario. RESEARCH DESIGN AND METHODS:We examined 25,697 patients from Ontario (6,052 and 19,645 patients with and without diabetes, respectively) who were hospitalized b...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/diacare.26.5.1427
更新日期:2003-05-01 00:00:00
abstract:OBJECTIVE:Some children with type 1 diabetes may be at risk of cognitive impairments, but mechanisms of this effect have not been confirmed. The objective of this study was to determine whether severe hypoglycemia (SH) in children with type 1 diabetes is associated with cognitive decline over 18 months. RESEARCH DESIG...
journal_title:Diabetes care
pub_type: 杂志文章,多中心研究
doi:10.2337/diacare.26.4.1100
更新日期:2003-04-01 00:00:00
abstract:OBJECTIVE:To examine the effect of prior meal ingestion on the glucose, insulin, and C-peptide response to a 50-g glucose challenge test in the third trimester of pregnancy. RESEARCH DESIGN AND METHODS:Ten pregnant women with gestational diabetes mellitus and 12 nondiabetic pregnant control subjects matched for age an...
journal_title:Diabetes care
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.2337/diacare.16.12.1551
更新日期:1993-12-01 00:00:00
abstract:OBJECTIVE:To determine the effects of a Dietary Approaches to Stop Hypertension (DASH) eating plan on metabolic risks in patients with the metabolic syndrome. RESEARCH DESIGN AND METHODS:This was a randomized controlled outpatient trial conducted on 116 patients with the metabolic syndrome. Three diets were prescribed...
journal_title:Diabetes care
pub_type: 杂志文章,随机对照试验
doi:10.2337/diacare.28.12.2823
更新日期:2005-12-01 00:00:00
abstract:OBJECTIVE:The effects of longitudinal changes in the visceral fat area (VFA), and other anthropometric indices, on the risk factors of metabolic syndrome were not studied. We calculated the changes in metabolic risk factors in relation to changes in certain anthropometric indices in a large-scale study of Japanese men....
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/dc11-1320
更新日期:2012-05-01 00:00:00
abstract:OBJECTIVE:Defects in insulin secretion and insulin action are the major abnormalities in the development of type 2 diabetes. In middle-aged subjects, elevated plasma proinsulin has been found to predict type 2 diabetes. Therefore, our aim was to study the longitudinal relationships between baseline determinations of in...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/diacare.27.6.1433
更新日期:2004-06-01 00:00:00
abstract:OBJECTIVE:Women with breast cancer and diabetes face worse outcomes than those with breast cancer without diabetes; however, the contribution of comorbidity to these disparities remains unclear. We evaluated the impact of diabetes on receipt of cancer treatments as well as mortality while accounting for other comorbidi...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/dc17-2012
更新日期:2018-04-01 00:00:00
abstract:OBJECTIVE:The objective of this study was to evaluate the association between foot ulcers (DFU) and lower-extremity amputation (LEA) and chronic kidney disease (CKD) in patients with diabetes. RESARCH DESIGN AND METHODS: This was a retrospective cohort study of individuals enrolled between 2002 and 2006 who were aged >...
journal_title:Diabetes care
pub_type: 杂志文章,多中心研究
doi:10.2337/dc07-2244
更新日期:2008-07-01 00:00:00
abstract::Whereas self-monitoring of blood glucose (SMBG) is the recommended source of information on which to make self-care decisions, patients frequently use estimates of their own blood glucose (BG). This study evaluated whether patients with insulin-dependent diabetes mellitus (IDDM) could learn to improve accuracy of BG e...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/diacare.12.5.313
更新日期:1989-05-01 00:00:00
abstract::OBJECTIVE--To determine and compare the abilities of various anthropometric measurements to predict the development of non-insulin-dependent diabetes mellitus (NIDDM) in Pima Indian men and women. RESEARCH DESIGN AND METHODS--A total of 290 male and 443 female Pima Indians were followed for up to 6 years for the devel...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/diacare.18.4.435
更新日期:1995-04-01 00:00:00
abstract:OBJECTIVE:This study investigated whether intimacy and autonomy in mother-daughter interactions and relational aspects of the self are associated with metabolic control in adolescent girls with type 1 diabetes. RESEARCH DESIGN AND METHODS:This cross-sectional study included 88 girls with diabetes (mean age 14.9 +/- 2....
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/diacare.27.3.709
更新日期:2004-03-01 00:00:00
abstract:OBJECTIVE:To assess the prevalence of diabetes and impaired glucose tolerance (IGT) in the adult population of Rio de Janeiro, a two-stage cross-sectional survey was carried out in a random sample of 2,051 individuals aged 30-69 years from Rio de Janeiro city in Brazil. RESEARCH DESIGN AND METHODS:Subjects were first ...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/diacare.19.6.663
更新日期:1996-06-01 00:00:00
abstract:OBJECTIVE:To 1) compare associations of diet-quality scores, which were inversely associated with cardiovascular disease, with incident type 2 diabetes and 2) test for differences in absolute-risk reduction across various strata. RESEARCH DESIGN AND METHODS:Men from the Health Professionals Follow-Up Study, who were i...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/dc10-2352
更新日期:2011-05-01 00:00:00
abstract:OBJECTIVE:Comparative effectiveness research methods are used to compare the effect of four distinct glucose-control strategies on subsequent myocardial infarction and nephropathy in type 2 diabetes. RESEARCH DESIGN AND METHODS:A total of 58,000 adults with type 2 diabetes and A1C <7% (53 mmol/mol) while taking two or...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/dc12-2675
更新日期:2013-11-01 00:00:00
abstract:OBJECTIVE:To investigate whether the use of exogenous estrogen is associated with changes in the severity of diabetic retinopathy and the incidence of macular edema. RESEARCH DESIGN AND METHODS:The study design involved observation of two well-defined cohorts of women with diabetes. One group was diagnosed with diabet...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/diacare.22.12.1984
更新日期:1999-12-01 00:00:00