Fuel and fluid homeostasis during long-term exercise in healthy subjects and type I diabetic patients.

abstract：OBJECTIVE:Bariatric surgery may induce remission of type 2 diabetes in obese patients. However, estimates of remission rates reported in the literature range from 25 to 81%, contributing to the uncertainty patients and physicians both face as they assess treatment options. This analysis attempts to reconcile the seemin...

journal_title：Diabetes care

authors： Isaman DJ,Rothberg AE,Herman WH

更新日期：2016-12-01 00:00:00

abstract：OBJECTIVE:In adults with diabetes, in vivo platelet activation is a marker for atherosclerosis and cardiovascular disease (CVD). This pilot study investigated whether adolescents with diabetes had evidence of increased in vivo platelet activation. RESEARCH DESIGN AND METHODS:In vivo platelet activation was compared in...

journal_title：Diabetes care

authors： Israels SJ,McNicol A,Dean HJ,Cognasse F,Sellers EA

更新日期：2014-08-01 00:00:00

abstract：OBJECTIVE:To describe the changes in serum levels of calcitonin in liraglutide- and placebo-treated patients in the Liraglutide Effect and Action in Diabetes: Evaluation of Cardiovascular Outcome Results-A Long Term Evaluation (LEADER) trial over a 3.5-5-year period. RESEARCH DESIGN AND METHODS:Patients (n = 9,340) wi...

journal_title：Diabetes care

authors： Hegedüs L,Sherman SI,Tuttle RM,von Scholten BJ,Rasmussen S,Karsbøl JD,Daniels GH,LEADER Publication Committee on behalf of the LEADER Trial Investigators.

更新日期：2018-03-01 00:00:00

abstract：OBJECTIVE:The current standard for hospital glucose management is point-of-care (POC) testing. We conducted a randomized controlled trial of real-time continuous glucose monitoring (RT-CGM) compared with POC in a non-intensive care unit (ICU) hospital setting. RESEARCH DESIGN AND METHODS:A total of 110 adults with typ...

journal_title：Diabetes care

authors： Fortmann AL,Spierling Bagsic SR,Talavera L,Garcia IM,Sandoval H,Hottinger A,Philis-Tsimikas A

更新日期：2020-11-01 00:00:00

abstract：OBJECTIVE:This article evaluates prediction of HbA(1c) during an 18-month randomized trial of intensive therapy (IT) versus usual care (UC) for type 1 diabetes in 142 youth. RESEARCH DESIGN AND METHODS:Patients received a composite score for self-management competence (SMC) that combined standardized scores on baselin...

journal_title：Diabetes care

authors： Wysocki T,Harris MA,Wilkinson K,Sadler M,Mauras N,White NH

更新日期：2003-07-01 00:00:00

abstract：OBJECTIVE:Prior studies have supported that waist circumference correlates better with visceral adipose tissue and is a better predictor of cardiovascular disease than are BMI and waist-to-hip ratio. In this study, we reexamine the role of waist size on the risk of hypertension and type 2 diabetes in African-origin pop...

journal_title：Diabetes care

authors： Okosun IS,Cooper RS,Rotimi CN,Osotimehin B,Forrester T

更新日期：1998-11-01 00:00:00

abstract：OBJECTIVE:To compare the efficacy, safety, and compliance of a nonremovable fiberglass cast boot and off-loading shoes in the treatment of diabetic plantar ulcers. RESEARCH DESIGN AND METHODS:Patients (n = 93) with noninfected, nonischemic plantar ulcers were included in this prospective nonrandomized study. Treatment...

journal_title：Diabetes care

authors： Ha Van G,Siney H,Hartmann-Heurtier A,Jacqueminet S,Greau F,Grimaldi A

更新日期：2003-10-01 00:00:00

abstract：OBJECTIVE:Blood pressure control can reduce the risk of coronary heart disease (CHD) among diabetic patients; however, it is not known whether the lowest risk of CHD is among diabetic patients with the lowest blood pressure level. RESEARCH DESIGN AND METHODS:We performed a prospective cohort study (2000-2009) on diabe...

journal_title：Diabetes care

authors： Zhao W,Katzmarzyk PT,Horswell R,Wang Y,Li W,Johnson J,Heymsfield SB,Cefalu WT,Ryan DH,Hu G

更新日期：2013-10-01 00:00:00

abstract：OBJECTIVE:To examine the association of stage of change with diet and exercise behaviors in response to a lifestyle intervention for Native Hawaiians (NHs). RESEARCH DESIGN AND METHODS:A family ('ohana) support lifestyle intervention was compared with a standard intervention in NHs with or at risk for diabetes in two ...

journal_title：Diabetes care

authors： Mau MK,Glanz K,Severino R,Grove JS,Johnson B,Curb JD

更新日期：2001-10-01 00:00:00

abstract：OBJECTIVE:This trial compared the efficacy and safety of the first oral glucagon-like peptide 1 (GLP-1) receptor agonist, oral semaglutide, as monotherapy with placebo in patients with type 2 diabetes managed by diet and exercise alone. Two estimands addressed two efficacy-related questions: a treatment policy estimand...

journal_title：Diabetes care

authors： Aroda VR,Rosenstock J,Terauchi Y,Altuntas Y,Lalic NM,Morales Villegas EC,Jeppesen OK,Christiansen E,Hertz CL,Haluzík M,PIONEER 1 Investigators.

更新日期：2019-09-01 00:00:00

abstract：OBJECTIVE:To investigate whether dietary phylloquinone and menaquinones intakes are related to risk of type 2 diabetes. RESEARCH DESIGN AND METHODS:We used data from a prospective cohort study in 38,094 Dutch men and women, aged 20-70 years. Dietary phylloquinone and menaquinones intakes were assessed using a validate...

journal_title：Diabetes care

authors： Beulens JW,van der A DL,Grobbee DE,Sluijs I,Spijkerman AM,van der Schouw YT

更新日期：2010-08-01 00:00:00

abstract：OBJECTIVE:We aimed at analyzing the frequency, clinical characteristics, and trends associated with the occurrence of diabetic ketoacidosis (DKA) at the onset of type 1 diabetes on the basis of long-term follow-up data. RESEARCH DESIGN AND METHODS:A total of 106 pediatric diabetes centers in Germany and Austria partic...

journal_title：Diabetes care

authors： Neu A,Hofer SE,Karges B,Oeverink R,Rosenbauer J,Holl RW,DPV Initiative and the German BMBF Competency Network for Diabetes Mellitus.

更新日期：2009-09-01 00:00:00

abstract：OBJECTIVE:No study has been conducted to evaluate the association between avascular necrosis of the femoral head and diabetes. This study's aim was to assess this issue in Taiwan. RESEARCH DESIGN AND METHODS:A population-based cohort study was performed to analyze the database of Taiwan's National Health Insurance Pro...

journal_title：Diabetes care

authors： Lai SW,Lin CL,Liao KF

更新日期：2019-01-01 00:00:00

abstract：OBJECTIVE:Insulin resistance plays a part in diabetic nephropathy (DN). The association between the peroxisome proliferator-activated receptor γ Pro to Ala alteration at codon 12 (Pro12Ala) polymorphism and the risk of insulin resistance has been confirmed. The association between the polymorphism and DN risk has also ...

journal_title：Diabetes care

authors： Zhang H,Zhu S,Chen J,Tang Y,Hu H,Mohan V,Venkatesan R,Wang J,Chen H

更新日期：2012-06-01 00:00:00

abstract：OBJECTIVE:Repaglinide is a newly developed oral blood glucose-lowering agent that exerts its effect by stimulating insulin secretion. This multicenter study was designed to compare the efficacy and safety of this drug with glyburide in a 1-year randomized double-blind study of outpatients with type 2 diabetes. RESEARC...

journal_title：Diabetes care

authors： Wolffenbuttel BH,Landgraf R

更新日期：1999-03-01 00:00:00

abstract：OBJECTIVE:To investigate the relationship between lifestyle counseling in primary care settings and clinical outcomes in patients with diabetes. RESEARCH DESIGN AND METHODS:We retrospectively studied hyperglycemic adults with diabetes treated at primary care practices between 2000 and 2014. We analyzed the relationshi...

journal_title：Diabetes care

authors： Zhang H,Goldberg SI,Hosomura N,Shubina M,Simonson DC,Testa MA,Turchin A

更新日期：2019-09-01 00:00:00

abstract：OBJECTIVE:To evaluate the utility of a semipermeable polymeric membrane dressing for the treatment of chronic diabetic foot ulcers. RESEARCH DESIGN AND METHODS:Nineteen subjects with either insulin-dependent diabetes mellitus (IDDM) or non-insulin-dependent diabetes mellitus (NIDDM) and foot ulcers were randomly assig...

journal_title：Diabetes care

authors： Blackman JD,Senseng D,Quinn L,Mazzone T

更新日期：1994-04-01 00:00:00

abstract：OBJECTIVE:To evaluate weight loss and cardiometabolic risk reduction achieved through an adapted Diabetes Prevention Program intervention among adults at high risk for cardiovascular disease (CVD) and diabetes. RESEARCH DESIGN AND METHODS:Eight health care facilities implemented a group-based lifestyle intervention be...

journal_title：Diabetes care

authors： Vanderwood KK,Hall TO,Harwell TS,Butcher MK,Helgerson SD,Montana Cardiovascular Disease and Diabetes Prevention Program Workgroup.

更新日期：2010-12-01 00:00:00

abstract：OBJECTIVE:To identify factors related to lipid testing among patients with diabetes who receive diabetes care from primary care physicians. RESEARCH DESIGN AND METHODS:North Carolina Medicare claims were used to identify individuals with diabetes who received diabetes care from primary care physicians. Lipid testing w...

journal_title：Diabetes care

authors： Massing MW,Henley NS,Carter-Edwards L,Schenck AP,Simpson RJ Jr

更新日期：2003-05-01 00:00:00

abstract：:The risk of severe hypoglycemia associated with the particular therapeutic approach of two University hospitals was assessed in 96% of all patients with insulin-dependent diabetes mellitus (IDDM) who had been admitted during a period of almost 3 yr to the diabetic wards of two hospitals and who participated in a struc...

journal_title：Diabetes care

authors： Mühlhauser I,Berger M,Sonnenberg G,Koch J,Jörgens V,Schernthaner G,Scholz V,Pädagogin D

更新日期：1985-05-01 00:00:00

abstract：OBJECTIVE:To study determinants of incident hyperglycemia in rural Indian mothers 6 years after delivery. RESEARCH DESIGN AND METHODS:The Pune Maternal Nutrition Study collected information in six villages near Pune on prepregnant characteristics and nutrition, physical activity, and glucose tolerance during pregnancy...

journal_title：Diabetes care

authors： Kulkarni SR,Fall CH,Joshi NV,Lubree HG,Deshpande VU,Pasarkar RV,Bhat DS,Naik SS,Yajnik CS

更新日期：2007-10-01 00:00:00

abstract：OBJECTIVE:To investigate the effect of normal aging on the protective responses against hypoglycemia, in view of the fact that type II diabetes is primarily a disease of aging, and its treatment is associated with risk of hypoglycemia with cognitive impairment. RESEARCH DESIGN AND METHODS:Plasma glucose was lowered st...

journal_title：Diabetes care

authors： Matyka K,Evans M,Lomas J,Cranston I,Macdonald I,Amiel SA

更新日期：1997-02-01 00:00:00

abstract：OBJECTIVE:We examined the association of lactation duration with incident type 2 diabetes among women with a history of gestational diabetes mellitus (GDM). RESEARCH DESIGN AND METHODS:We monitored 4,372 women with a history of GDM participating in the Nurses' Health Study II for incident type 2 diabetes over 25 years...

journal_title：Diabetes care

authors： Ley SH,Chavarro JE,Li M,Bao W,Hinkle SN,Wander PL,Rich-Edwards J,Olsen S,Vaag A,Damm P,Grunnet LG,Mills JL,Hu FB,Zhang C

更新日期：2020-04-01 00:00:00

abstract：OBJECTIVE:To describe the clinical experience and the pharmacokinetics of U-500 regular insulin in severely insulin-resistant obese type 2 diabetic patients. RESEARCH DESIGN AND METHODS:Patients requiring >200 units of insulin with A1C levels >8.0% were switched to U-500 regular insulin. For the pharmacokinetic study,...

journal_title：Diabetes care

authors： Davidson MB,Navar MD,Echeverry D,Duran P

更新日期：2010-02-01 00:00:00

abstract：OBJECTIVE:To examine the hypothesis that hyperinsulinemia among relatives of NIDDM probands will increase the prevalence of DLPs, we measured insulin levels and examined the frequency of DLPs among NIDDM pedigree members. RESEARCH DESIGN AND METHODS:We performed 2-h 75-g OGTTs and measured lipid and insulin levels of ...

journal_title：Diabetes care

authors： Schumacher MC,Maxwell TM,Wu LL,Hunt SC,Williams RR,Elbein SC

更新日期：1992-10-01 00:00:00

abstract：OBJECTIVE:To study the effect of birth weight on risk of type 2 diabetes in the schoolchildren in Taiwan. RESEARCH DESIGN AND METHODS:From 1992 to 1997, all schoolchildren aged 6-18 years were screened for diabetes in Taiwan Province. This cohort consisted of 1,966 patients with diabetes and 1,780 randomly selected su...

journal_title：Diabetes care

authors： Wei JN,Sung FC,Li CY,Chang CH,Lin RS,Lin CC,Chiang CC,Chuang LM

更新日期：2003-02-01 00:00:00

abstract：OBJECTIVE:This double-blind, placebo-controlled, randomized, multicenter, parallel-group study compared the efficacy, safety, and tolerability of Technosphere insulin with Technosphere powder as placebo in insulin-naive type 2 diabetic patients whose diabetes was suboptimally controlled with oral antidiabetic agents. ...

journal_title：Diabetes care

authors： Rosenstock J,Bergenstal R,Defronzo RA,Hirsch IB,Klonoff D,Boss AH,Kramer D,Petrucci R,Yu W,Levy B,0008 Study Group.

更新日期：2008-11-01 00:00:00

abstract：OBJECTIVE:To investigate the efficacy and safety of prandial Technosphere inhaled insulin (TI), an inhaled insulin with a distinct time action profile, in insulin-naïve type 2 diabetes (T2D) inadequately controlled on oral antidiabetes agents (OADs). RESEARCH DESIGN AND METHODS:Subjects with T2D with HbA1c levels ≥7.5...

journal_title：Diabetes care

authors： Rosenstock J,Franco D,Korpachev V,Shumel B,Ma Y,Baughman R,Amin N,McGill JB,Affinity 2 Study Group.

更新日期：2015-12-01 00:00:00

abstract：OBJECTIVE:We have previously shown that 300 kcal from glucose intake induces a significant increase in reactive oxygen species (ROS) generation and nuclear factor-kappaB (NF-kappaB) binding in the circulating mononuclear cells in healthy normal subjects. We hypothesized that the intake of 300 calories as orange juice o...

journal_title：Diabetes care

authors： Ghanim H,Mohanty P,Pathak R,Chaudhuri A,Sia CL,Dandona P

更新日期：2007-06-01 00:00:00

abstract：OBJECTIVE:To determine the effect of a high-protein (HP) diet compared with a low-protein (LP) diet on weight loss, resting energy expenditure (REE), and the thermic effect of food (TEF) in subjects with type 2 diabetes during moderate energy restriction. RESEARCH DESIGN AND METHODS:In this study, 26 obese subjects wi...

journal_title：Diabetes care

authors： Luscombe ND,Clifton PM,Noakes M,Parker B,Wittert G

更新日期：2002-04-01 00:00:00