Peroxisome proliferator-activated receptor γ polymorphism Pro12Ala Is associated with nephropathy in type 2 diabetes: evidence from meta-analysis of 18 studies.

abstract：:The affinity of human (recombinant DNA) insulin and porcine insulin to preformed IgG-insulin antibodies of insulin-treated diabetic individuals was studied in 29 insulin-treated diabetic patients. The binding of 125I-human insulin and 125I-porcine insulin with antibodies was similar in the group of patients without in...

journal_title：Diabetes care

authors： Schernthaner G

更新日期：1982-11-01 00:00:00

abstract：OBJECTIVE:To describe market trends for antidiabetic drugs, focusing on newly approved drugs, concomitant use of antidiabetic drugs, and effects of safety concerns and access restrictions on thiazolidinedione use. RESEARCH DESIGN AND METHODS:Nationally projected data on antidiabetic prescriptions for adults dispensed ...

journal_title：Diabetes care

authors： Hampp C,Borders-Hemphill V,Moeny DG,Wysowski DK

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:To investigate whether intraperitoneal insulin (IPII) decreases the levels of circulating chylomicron remnants in patients with insulin-dependent diabetes mellitus (IDDM). RESEARCH DESIGN AND METHODS:Eight nonobese, normolipidemic IDDM patients were studied twice: before (while on subcutaneous insulin) and 6...

journal_title：Diabetes care

authors： Georgopoulos A,Saudek CD

更新日期：1994-11-01 00:00:00

abstract：OBJECTIVE:Our objective was to analyze the prevalence, incidence, and mortality of diabetes in a population of 280,539 inhabitants. RESEARCH DESIGN AND METHODS:The incidence, prevalence, and deaths from diabetes at all ages of a population have been prospectively followed in the county of Skaraborg, Sweden, since 1991...

journal_title：Diabetes care

authors： Berger B,Stenström G,Sundkvist G

更新日期：1999-05-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to determine whether the use of meal bolus alarms would result in fewer missed meal boluses per week in youth with type 1 diabetes using continuous subcutaneous insulin infusion (CSII) therapy. RESEARCH DESIGN AND METHODS:This was a randomized trial of 48 youth using CSII, who were ...

journal_title：Diabetes care

authors： Chase HP,Horner B,McFann K,Yetzer H,Gaston J,Banion C,Fiallo-Scharer R,Slover R,Klingensmith G

更新日期：2006-05-01 00:00:00

abstract：OBJECTIVE:To compare the prevalence of lumbar spondylolytic spondylolisthesis (LSS) in nondiabetic and diabetic subjects. RESEARCH DESIGN AND METHODS:A cross-sectional study of 1,147 randomly selected nondiabetic subjects and 892 non-insulin-dependent diabetes mellitus (NIDDM) patients, 45-64 years of age. LSS was dia...

journal_title：Diabetes care

authors： Virta L,Rönnemaa T,Laakso M

更新日期：1994-06-01 00:00:00

abstract：OBJECTIVE:Type 1 diabetes mellitus causes increased carotid intima-media thickness (IMT) in adults. We evaluated IMT in young subjects with type 1 diabetes. RESEARCH DESIGN AND METHODS:Participants with type 1 diabetes (N = 402) were matched to controls (N = 206) by age, sex, and race or ethnicity. Anthropometric and ...

journal_title：Diabetes care

authors： Urbina EM,Dabelea D,D'Agostino RB Jr,Shah AS,Dolan LM,Hamman RF,Daniels SR,Marcovina S,Wadwa RP

更新日期：2013-09-01 00:00:00

abstract：OBJECTIVE:Conjugated linoleic acid (CLA) is a group of dietary fatty acids with antiobesity and antidiabetic effects in some animals. The trans10cis12 (t10c12) CLA isomer seems to cause these effects, including improved insulin sensitivity. Whether such isomer-specific effects occur in humans is unknown. The aim of thi...

journal_title：Diabetes care

authors： Risérus U,Arner P,Brismar K,Vessby B

更新日期：2002-09-01 00:00:00

abstract：OBJECTIVE:To determine whether low-glycemic index (GI) diets have clinical utility in overweight patients with non-insulin-dependent diabetes mellitus (NIDDM). RESEARCH DESIGN AND METHODS:Six patients with NIDDM were studied on both high- and low-GI diets of 6-wk duration with metabolic diets with a randomized crossov...

journal_title：Diabetes care

authors： Wolever TM,Jenkins DJ,Vuksan V,Jenkins AL,Wong GS,Josse RG

更新日期：1992-04-01 00:00:00

abstract：OBJECTIVE:To determine the impact of changes to treatment on the incidence of severe hypoglycemia and its risk factors in a large population-based cohort of children with type 1 diabetes. RESEARCH DESIGN AND METHODS:The cohort consisted of 1,335 children (age at entry 9.5 +/- 4.3 years [mean +/- SD], range 0-18), yiel...

journal_title：Diabetes care

authors： Bulsara MK,Holman CD,Davis EA,Jones TW

更新日期：2004-10-01 00:00:00

abstract：:One-third of men with obesity or type 2 diabetes have subnormal free testosterone concentrations. The lower free testosterone concentrations are observed in obese men at all ages, including adolescents at completion of puberty. The gonadotropin concentrations in these males are inappropriately normal; thus, these pati...

journal_title：Diabetes care

authors： Dhindsa S,Ghanim H,Batra M,Dandona P

更新日期：2018-07-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to increase the cross-state comparability of diabetes mortality statistics related in the U.S. and Mexico. RESEARCH DESIGN AND METHODS:We used multinomial logistic regression to estimate the effects of individual and community factors on a death for which diabetes was recorded as on...

journal_title：Diabetes care

authors： Murray CJ,Dias RH,Kulkarni SC,Lozano R,Stevens GA,Ezzati M

更新日期：2008-03-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to evaluate the associations of BMI versus metabolic syndrome with cardiovascular diseases (CVDs) in elderly Chinese individuals. RESEARCH DESIGN AND METHODS:We conducted a population-based cross-sectional study in an urban sample of 2,334 elderly subjects (943 men and 1,391 wom...

journal_title：Diabetes care

authors： He Y,Jiang B,Wang J,Feng K,Chang Q,Zhu S,Fan L,Li X,Hu FB

更新日期：2007-08-01 00:00:00

abstract：OBJECTIVE:Longitudinal changes in GAD antibody (Ab) and ICA512/IA-2 (ICA512) Ab were examined in relation to age at the onset of diabetes and autoimmunity against the thyroid gland. RESEARCH DESIGN AND METHODS:GADAb, ICA512Ab, and antithyroid autoantibody were examined at onset in 40 juvenile-onset IDDM patients (17 m...

journal_title：Diabetes care

authors： Yokota I,Matsuda J,Naito E,Ito M,Shima K,Kuroda Y

更新日期：1998-01-01 00:00:00

abstract：OBJECTIVE:Obesity is associated with alterations in corticolimbic-striatal brain regions involved in food motivation and reward. Stress and the presence of food cues may each motivate eating and engage corticolimibic-striatal neurocircuitry. It is unknown how these factors interact to influence brain responses and whet...

journal_title：Diabetes care

authors： Jastreboff AM,Sinha R,Lacadie C,Small DM,Sherwin RS,Potenza MN

更新日期：2013-02-01 00:00:00

abstract：:Severe hypoglycemia (SH) is a significant problem for many patients with type I diabetes and presents a major barrier to optimal diabetes control. A critical task facing diabetes research is to understand, predict, and reduce the risk of SH in insulin-treated patients. The purpose of this article is to propose a biops...

journal_title：Diabetes care

authors： Gonder-Frederick L,Cox D,Kovatchev B,Schlundt D,Clarke W

更新日期：1997-04-01 00:00:00

abstract：:OBJECTIVE Previous studies have demonstrated aberrant glucagon physiology in the setting of type 1 diabetes (T1D) but have not addressed the potential impact of ambient glycemia on this glucagon response. Thus, our objective was to evaluate the impact of euglycemia versus hyperglycemia on the glucagon response to an o...

journal_title：Diabetes care

authors： Kramer CK,Borgoño CA,Van Nostrand P,Retnakaran R,Zinman B

更新日期：2014-04-01 00:00:00

abstract：OBJECTIVE:Diet is the cornerstone treatment of patients with gestational diabetes mellitus (GDM), but its role in maternal and newborn outcomes has been scarcely studied. The purpose of this study was to analyze the efficacy of dietary interventions on maternal or newborn outcomes in patients with GDM. RESEARCH DESIGN...

journal_title：Diabetes care

authors： Viana LV,Gross JL,Azevedo MJ

更新日期：2014-12-01 00:00:00

abstract：OBJECTIVE:To determine whether there is a familial abnormality in erythrocyte Na/Li countertransport (CT) kinetics in the approximate one-third of type 1 diabetic patients that succumb to a familial predisposition to nephropathy. RESEARCH DESIGN AND METHODS:Erythrocyte Na/Li CT kinetics were measured in nondiabetic fi...

journal_title：Diabetes care

authors： Mead PA,Wilkinson R,Thomas TH

更新日期：2001-03-01 00:00:00

abstract：OBJECTIVE:To evaluate the effect of gastric emptying on postprandial insulin requirement in insulin-dependent diabetes mellitus (IDDM) patients with and without gastroparesis. RESEARCH DESIGN AND METHODS:Postprandial insulin requirement and gastric emptying were simultaneously evaluated in five IDDM patients with gast...

journal_title：Diabetes care

authors： Ishii M,Nakamura T,Kasai F,Onuma T,Baba T,Takebe K

更新日期：1994-08-01 00:00:00

abstract：:Supine and standing heart rate and heart rate responses to deep breathing and standing up (the 30-to-15 ratio), indices of autonomic nervous function, were measured during each trimester and postpartum in 25 women with insulin-dependent diabetes and 10 nondiabetic women. The groups did not differ with respect to auton...

journal_title：Diabetes care

authors： Airaksinen KE,Salmela PI,Ikäheimo MJ,Kirkinen P,Linnaluoto MK,Takkunen JT

更新日期：1987-11-01 00:00:00

abstract：OBJECTIVE:To study the effect of vitamin E supplementation on platelet hyperaggregability in type 1 diabetic patients. RESEARCH DESIGN AND METHODS:Written informed consent according to the Institutional Review Board on Human Experimentation guidelines was obtained from diabetic patients (n = 29) and their age-matched ...

journal_title：Diabetes care

authors： Jain SK,Krueger KS,McVie R,Jaramillo JJ,Palmer M,Smith T

更新日期：1998-09-01 00:00:00

abstract：OBJECTIVE:Hypertriglyceridemia is associated with cardiovascular disease in diabetes. Fibrates effectively lower, but do not always normalize, serum triglyceride levels. Fish oil supplements may then be added to lower serum triglyceride levels. Doubt remains whether the net effect of fish oil intake on glycemic control...

journal_title：Diabetes care

authors： Friedberg CE,Janssen MJ,Heine RJ,Grobbee DE

更新日期：1998-04-01 00:00:00

abstract：:Considerable attention has been focused on the importance of physical activity in improving the diabetic state in obese, non-insulin-dependent diabetic patients. Because this patient population tends to be sedentary, this challenge requires an active effort involving the patient and health-care providers. The latter m...

journal_title：Diabetes care

authors： Beeken RK

更新日期：1980-09-01 00:00:00

abstract：OBJECTIVE:Hypoxia plays a major pathogenic role in diabetic nephropathy (DN). We have investigated in this study the effect of hypoxia-inducible factor 1 α subunit (HIF1A) genetic polymorphisms on the development of DN. RESEARCH DESIGN AND METHODS:In 1,165 American type 1 diabetic patients with and without DN selected...

journal_title：Diabetes care

authors： Gu HF,Zheng X,Abu Seman N,Gu T,Botusan IR,Sunkari VG,Lokman EF,Brismar K,Catrina SB

更新日期：2013-02-01 00:00:00

abstract：OBJECTIVE:To assess the prevalence of diabetes and impaired glucose tolerance (IGT) in the adult population of Rio de Janeiro, a two-stage cross-sectional survey was carried out in a random sample of 2,051 individuals aged 30-69 years from Rio de Janeiro city in Brazil. RESEARCH DESIGN AND METHODS:Subjects were first ...

journal_title：Diabetes care

authors： Oliveira JE,Milech A,Franco LJ

更新日期：1996-06-01 00:00:00

abstract：OBJECTIVE:It has been suggested that individuals with the condition known as metabolically healthy obesity (MHO) may not have the same increased risk for the development of metabolic abnormalities as their non-metabolically healthy counterparts. However, the validity of this concept has recently been challenged, since ...

journal_title：Diabetes care

authors： Gómez-Ambrosi J,Catalán V,Rodríguez A,Andrada P,Ramírez B,Ibáñez P,Vila N,Romero S,Margall MA,Gil MJ,Moncada R,Valentí V,Silva C,Salvador J,Frühbeck G

更新日期：2014-10-01 00:00:00

abstract：OBJECTIVE:A cohort (n = 277) was followed from diabetes diagnosis to evaluate longitudinal glycemic control, urinary C-peptide levels, and certain features of diabetes self-management. RESEARCH DESIGN AND METHODS:Unselected cases with IDDM, who were less than 30 yr of age, were identified at diagnosis from a 28-county...

journal_title：Diabetes care

authors： Allen C,Zaccaro DJ,Palta M,Klein R,Duck SC,D'Alessio DJ

更新日期：1992-08-01 00:00:00

abstract：OBJECTIVE:The relationship between coronary endothelial function and insulin resistance remains speculative. We sought to determine whether pioglitazone, an insulin-sensitizing peroxisome proliferator-activated receptor (PPAR)-gamma agonist, improves cardiac endothelial function in individuals with type 2 diabetes. RE...

journal_title：Diabetes care

authors： McMahon GT,Plutzky J,Daher E,Bhattacharyya T,Grunberger G,DiCarli MF

更新日期：2005-05-01 00:00:00

abstract：OBJECTIVE:The goal of this study was to determine whether the haptoglobin (Hp) genotype was predictive of restenosis and major adverse cardiac events (MACEs) after percutaneous transluminal coronary angioplasty (PTCA) in individuals with diabetes. RESEARCH DESIGN AND METHODS:A consecutive series of 935 diabetic patien...

journal_title：Diabetes care

authors： Roguin A,Koch W,Kastrati A,Aronson D,Schomig A,Levy AP

更新日期：2003-09-01 00:00:00