Leukocyte profiles differ between type 1 and type 2 diabetes and are associated with metabolic phenotypes: results from the German Diabetes Study (GDS).

abstract：OBJECTIVE:Growth deferentiation factor-15 (GDF-15) is involved in inflammation and apoptosis. Expression is induced in the heart in response to ischemia and in atherosclerotic plaques. The aim of this study was to investigate GDF-15 levels in relation to all-cause mortality, cardiovascular mortality and morbidity, decl...

journal_title：Diabetes care

authors： Lajer M,Jorsal A,Tarnow L,Parving HH,Rossing P

更新日期：2010-07-01 00:00:00

abstract：:OBJECTIVE Pharmacological profiles of biphasic insulin aspart 30/70 (BIAsp 30) once daily (OD), twice daily (b.i.d.), and three times daily (t.i.d.) were compared with other insulin regimens in two crossover glucose clamp studies of insulin-treated type 2 diabetic patients. RESEARCH DESIGNS AND METHODS Study 1 consist...

journal_title：Diabetes care

authors： Heise T,Heinemann L,Hövelmann U,Brauns B,Nosek L,Haahr HL,Olsen KJ

更新日期：2009-08-01 00:00:00

abstract：OBJECTIVE:The Diabetes Control and Complications Trial (DCCT) demonstrated the powerful impact of glycemic control on the early manifestations of microvascular complications. Contemporary prospective data on the evolution of macrovascular and late microvascular complications of type 1 diabetes are limited. The Epidemio...

journal_title：Diabetes care

authors：

更新日期：1999-01-01 00:00:00

abstract：OBJECTIVE:This study compared heart rate variability (HRV) parameters in youth with and without type 1 diabetes and explored potential contributors of altered HRV. RESEARCH DESIGN AND METHODS:HRV parameters were measured among 354 youth with type 1 diabetes (mean age 18.8 years, diabetes duration 9.8 years, and mean A...

journal_title：Diabetes care

authors： Jaiswal M,Urbina EM,Wadwa RP,Talton JW,D'Agostino RB Jr,Hamman RF,Fingerlin TE,Daniels S,Marcovina SM,Dolan LM,Dabelea D

更新日期：2013-01-01 00:00:00

abstract：OBJECTIVE:To characterize the relationship of subclinical and clinical eating disorders to HbA1c values in women with IDDM. RESEARCH DESIGN AND METHODS:Ninety women with IDDM (18-46 years of age) were recruited from diabetes clinics throughout Connecticut and Massachusetts. Subjects were categorized into one of three ...

journal_title：Diabetes care

authors： Affenito SG,Backstrand JR,Welch GW,Lammi-Keefe CJ,Rodriguez NR,Adams CH

更新日期：1997-02-01 00:00:00

abstract：:It has generally been assumed that oral candidiasis occurs with increased frequency in patients with diabetes mellitus. To evaluate this, we compared the frequency and severity of oral Candida colonization in 60 patients with insulin-dependent diabetes mellitus (IDDM) admitted to a low-intensity-care diabetes unit wit...

journal_title：Diabetes care

authors： Bartholomew GA,Rodu B,Bell DS

更新日期：1987-09-01 00:00:00

abstract：OBJECTIVE:In a few previous studies, cardiovascular disease (CVD) risk factors (RFs) have been shown to predict diabetes. Our objective was to determine whether the presence of CVD RFs predict the eventual development of diabetes after controlling for known RFs, such as directly measured insulin resistance and obesity....

journal_title：Diabetes care

authors： D'Agostino RB Jr,Hamman RF,Karter AJ,Mykkanen L,Wagenknecht LE,Haffner SM,Insulin Resistance Atherosclerosis Study Investigators.

更新日期：2004-09-01 00:00:00

abstract：OBJECTIVE:High-deductible health plans (HDHPs) are now the predominant commercial health insurance benefit in the U.S. We sought to determine the effects of HDHPs on emergency department and hospital care, adverse outcomes, and total health care expenditures among patients with diabetes. RESEARCH DESIGN AND METHODS:We...

journal_title：Diabetes care

authors： Wharam JF,Zhang F,Eggleston EM,Lu CY,Soumerai SB,Ross-Degnan D

更新日期：2018-05-01 00:00:00

abstract：:In past studies on the psychological aspects of diabetes mellitus, symptoms of depression have been identified as the most common manifestation among diabetic patients. Other psychological manifestations have been anxiety, hypochondriasis, increased dependence and passivity, and poor self-image. Ten insulin-dependent ...

journal_title：Diabetes care

authors： Dupuis A

更新日期：1980-01-01 00:00:00

abstract：OBJECTIVE:To determine the association between triglyceride levels and lower-extremity amputation (LEA) risk in a large diabetic cohort. RESEARCH DESIGN AND METHODS:This is a 10-year survey follow-up study (from 1995-2006) of 28,701 diabetic patients with a baseline triglyceride measure. All patients were fully insure...

journal_title：Diabetes care

authors： Callaghan BC,Feldman E,Liu J,Kerber K,Pop-Busui R,Moffet H,Karter AJ

更新日期：2011-03-01 00:00:00

abstract：OBJECTIVE:The effect of therapeutic strategies on cardiovascular (CV) disease can be evaluated by monitoring changes in CV risk biomarkers. This study investigated the effect of a structured self-monitoring of blood glucose (SMBG) protocol and the resulting improvements in glycemic control on changes in high-sensitivit...

journal_title：Diabetes care

authors： Schnell O,Amann-Zalan I,Jelsovsky Z,Moritz A,Bermejo JL,Parkin CG,Schweitzer MA,Fisher L,Polonsky WH

更新日期：2013-07-01 00:00:00

abstract：OBJECTIVE:The International Diabetes Federation (IDF) has proposed a new definition of the metabolic syndrome that emphasizes central adiposity as determined by ethnic group-specific thresholds of waist circumference. The objective of this study was to estimate the prevalence of this syndrome using the IDF definition a...

journal_title：Diabetes care

authors： Ford ES

更新日期：2005-11-01 00:00:00

abstract：OBJECTIVE:To examine the acute glucose-lowering effects of aerobic exercise in children and adolescents with type 1 diabetes. RESEARCH DESIGN AND METHODS:Fifty children and adolescents with type 1 diabetes (ages 10 to <18 years) were studied during exercise. The 75-min exercise session consisted of four 15-min periods...

journal_title：Diabetes care

authors： Tansey MJ,Tsalikian E,Beck RW,Mauras N,Buckingham BA,Weinzimer SA,Janz KF,Kollman C,Xing D,Ruedy KJ,Steffes MW,Borland TM,Singh RJ,Tamborlane WV,Diabetes Research in Children Network (DirecNet) Study Group.

更新日期：2006-01-01 00:00:00

abstract：OBJECTIVE:To determine the fatty acid composition of serum phospholipid, triglyceride, and cholesterol ester fractions and to analyze the lipid profile of microalbuminuric type 2 diabetic patients. RESEARCH DESIGN AND METHODS:A case-control study was conducted with 72 patients: 37 were normoalbuminuric (urinary albumi...

journal_title：Diabetes care

authors： Perassolo MS,Almeida JC,Prá RL,Mello VD,Maia AL,Moulin CC,Camargo JL,Zelmanovitz T,Azevedo MJ,Gross JL

更新日期：2003-03-01 00:00:00

abstract：OBJECTIVE:To improve prognosis, it is important to predict the incidence of renal failure and cardiovascular disease in type 2 diabetic patients before the progression to advanced nephropathy. We investigated the predictive effects of urinary liver-type fatty acid-binding protein (L-FABP), which is associated with rena...

journal_title：Diabetes care

authors： Araki S,Haneda M,Koya D,Sugaya T,Isshiki K,Kume S,Kashiwagi A,Uzu T,Maegawa H

更新日期：2013-05-01 00:00:00

abstract：OBJECTIVE:To compare the cost and time to diagnosis associated with several screening strategies for diabetes in women with histories of gestational diabetes mellitus (GDM). RESEARCH DESIGN AND METHODS:We simulated screening for diabetes with fasting plasma glucose (FPG), a 2-h oral glucose tolerance test (OGTT), and ...

journal_title：Diabetes care

authors： Kim C,Herman WH,Vijan S

更新日期：2007-05-01 00:00:00

abstract：OBJECTIVE:To compare the health service utilization and long-term outcomes of acute myocardial infarction (AMI) patients with and without diabetes in Ontario. RESEARCH DESIGN AND METHODS:We examined 25,697 patients from Ontario (6,052 and 19,645 patients with and without diabetes, respectively) who were hospitalized b...

journal_title：Diabetes care

authors： Alter DA,Khaykin Y,Austin PC,Tu JV,Hux JE

更新日期：2003-05-01 00:00:00

abstract：OBJECTIVE:Preanalytical processing of blood samples can affect plasma glucose measurement because ongoing glycolysis by cells prior to centrifugation can lower its concentration. In June 2017, ACT Pathology changed the processing of oral glucose tolerance test (OGTT) blood samples for pregnant women from a delayed to a...

journal_title：Diabetes care

authors： Potter JM,Hickman PE,Oakman C,Woods C,Nolan CJ

更新日期：2020-07-01 00:00:00

abstract：OBJECTIVE:Bimodality in the distribution of glucose has been used to define the cut point for the diagnosis of diabetes. Previous studies on bimodality have primarily been in populations with a high prevalence of type 2 diabetes, including one study in a white Caucasian population. All studies included participants wit...

journal_title：Diabetes care

authors： Vistisen D,Colagiuri S,Borch-Johnsen K,DETECT-2 Collaboration.

更新日期：2009-03-01 00:00:00

abstract：OBJECTIVE:To determine whether diabetes risk is influenced by which parent (a parental history of diabetes is a well-documented risk factor for NIDDM) is reported to have diabetes. RESEARCH DESIGN AND METHODS:We compared the prevalence of NIDDM and IGT for 4914 subjects according to their parental history of diabetes ...

journal_title：Diabetes care

authors： Mitchell BD,Valdez R,Hazuda HP,Haffner SM,Monterrosa A,Stern MP

更新日期：1993-09-01 00:00:00

abstract：OBJECTIVE:To compare the efficacy and safety of new insulin glargine 300 units/mL (Gla-300) with glargine 100 units/mL (Gla-100) in people with type 2 diabetes on basal insulin (≥42 units/day) plus mealtime insulin. RESEARCH DESIGN AND METHODS:EDITION 1 (NCT01499082) was a 6-month, multinational, open-label, parallel-...

journal_title：Diabetes care

authors： Riddle MC,Bolli GB,Ziemen M,Muehlen-Bartmer I,Bizet F,Home PD,EDITION 1 Study Investigators.

更新日期：2014-10-01 00:00:00

abstract：:A semiclosed loop, bedside insulin infusion system using a simple basal infusion algorithm consisting of a linear transition between two insulin delivery rates as blood glucose (BG) increases has been developed. A theoretical study using computer simulation has now been undertaken to examine the effect of BG sampling ...

journal_title：Diabetes care

authors： Furler SM,Kraegen EW,Smallwood RH,Chisholm DJ

更新日期：1985-11-01 00:00:00

abstract：OBJECTIVE:To test the effect of an automated system providing real-time estimates of HbA(1c), glucose variability, and risk for hypoglycemia. RESEARCH DESIGN AND METHODS:For 1 year, 120 adults with type 1 diabetes (69 female/51 male, age = 39.1 [14.3] years, duration of diabetes 20.3 [12.9] years, HbA(1c) = 8.0 [1.5])...

journal_title：Diabetes care

authors： Kovatchev BP,Mendosa P,Anderson S,Hawley JS,Ritterband LM,Gonder-Frederick L

更新日期：2011-02-01 00:00:00

abstract：OBJECTIVE:To determine whether adolescents with type 1 diabetes have left ventricular functional changes at rest and during acute exercise and whether these changes are affected by metabolic control and diabetes duration. RESEARCH DESIGN AND METHODS:The study evaluated 53 adolescents with type 1 diabetes and 22 contro...

journal_title：Diabetes care

authors： Gusso S,Pinto TE,Baldi JC,Robinson E,Cutfield WS,Hofman PL

更新日期：2012-10-01 00:00:00

abstract：OBJECTIVE:The goal was to develop a new index of insulin sensitivity in patients with type 1 diabetes estimated from continuous glucose monitoring (CGM) and subcutaneous insulin delivery data under carefully controlled conditions. RESEARCH DESIGN AND METHODS:The database consists of 12 subjects with type 1 diabetes, s...

journal_title：Diabetes care

authors： Schiavon M,Dalla Man C,Kudva YC,Basu A,Cobelli C

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:We aimed to identify hemoglobin A1c (HbA1c)-associated genetic variants and examine their implications for glycemic status evaluated by HbA1c in U.S. Hispanics/Latinos with diverse genetic ancestries. RESEARCH DESIGN AND METHODS:We conducted a genome-wide association study (GWAS) of HbA1c in 9,636 U.S. Hispa...

journal_title：Diabetes care

authors： Moon JY,Louie TL,Jain D,Sofer T,Schurmann C,Below JE,Lai CQ,Aviles-Santa ML,Talavera GA,Smith CE,Petty LE,Bottinger EP,Chen YI,Taylor KD,Daviglus ML,Cai J,Wang T,Tucker KL,Ordovás JM,Hanis CL,Loos RJF,Schneiderm

更新日期：2019-09-01 00:00:00

abstract：OBJECTIVE:To determine the effect of metformin on the acute metabolic response to submaximal exercise, the effect of exercise on plasma metformin concentrations, and the interaction between metformin and exercise on the subsequent response to a standardized meal. RESEARCH DESIGN AND METHODS:Ten participants with type ...

journal_title：Diabetes care

authors： Boulé NG,Robert C,Bell GJ,Johnson ST,Bell RC,Lewanczuk RZ,Gabr RQ,Brocks DR

更新日期：2011-07-01 00:00:00

abstract：OBJECTIVE:To examine mortality rates and causes of death among subjects diagnosed with type 1 diabetes aged

journal_title：Diabetes care

authors： Feltbower RG,Bodansky HJ,Patterson CC,Parslow RC,Stephenson CR,Reynolds C,McKinney PA

更新日期：2008-05-01 00:00:00

abstract：OBJECTIVE:To study the relationship between the prevalence of impaired glucose tolerance (IGT) and non-insulin-dependent diabetes mellitus (NIDDM) across populations of the Pacific Ocean region to assess whether variability in those two proportions followed some predictable pattern related to modernization of life-styl...

journal_title：Diabetes care

authors： Dowse GK,Zimmet PZ,King H

更新日期：1991-11-01 00:00:00

abstract：:A representative sample of 817 American women aged 20-44 yr who were not pregnant and had no medical history of diabetes were given 75-g 2-h oral glucose tolerance tests (OGTTs). Although these conditions are somewhat different from those recommended for pregnant women (100 g glucose, 3-h OGTT), 3.8% of the women migh...

journal_title：Diabetes care

authors： Harris MI

更新日期：1988-05-01 00:00:00