Fatty acid composition of serum lipid fractions in type 2 diabetic patients with microalbuminuria.

abstract：:Due to the inherent pharmacokinetic properties of available insulins, normoglycemia is rarely, if ever, achieved in insulin-dependent diabetic patients without compromising their quality of life. Subcutaneous insulin absorption is influenced by many factors, among which the associated state of insulin (hexameric) in p...

journal_title：Diabetes care

authors： Brange J,Owens DR,Kang S,Vølund A

更新日期：1990-09-01 00:00:00

abstract：:We evaluated the epidemiology of diabetic ketoacidosis in the period 1960-1979. In Frederiksborg County, Denmark, the incidence of ketoacidosis at the county hospital increased from 60 per 100,000 in the period 1943-1963 to 120 per 100,000 in the period 1960-1979. In the investigation period we found an increasing inc...

journal_title：Diabetes care

authors： Ellemann K,Soerensen JN,Pedersen L,Edsberg B,Andersen OO

更新日期：1984-11-01 00:00:00

abstract：:Neutral regular human insulin (Novo) (derived from porcine insulin) and porcine insulin were administered by subcutaneous (s.c.) injection into the anterior abdominal wall in two different groups of six normal male subjects. The insulin dosage was 0.075 IU/kg body wt; diluting medium was used to obtain control values....

journal_title：Diabetes care

authors： Owens DR,Jones MK,Birtwell AJ,Jones IR,Hayes TM,Heding LG

更新日期：1983-03-01 00:00:00

abstract：OBJECTIVE:Given the transient nature of exercise-induced improvements in insulin sensitivity, it has been speculated that daily exercise is preferred to maximize the benefits of exercise for glycemic control. The current study investigates the impact of daily exercise versus exercise performed every other day on glycem...

journal_title：Diabetes care

authors： van Dijk JW,Tummers K,Stehouwer CD,Hartgens F,van Loon LJ

更新日期：2012-05-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to determine whether the use of meal bolus alarms would result in fewer missed meal boluses per week in youth with type 1 diabetes using continuous subcutaneous insulin infusion (CSII) therapy. RESEARCH DESIGN AND METHODS:This was a randomized trial of 48 youth using CSII, who were ...

journal_title：Diabetes care

authors： Chase HP,Horner B,McFann K,Yetzer H,Gaston J,Banion C,Fiallo-Scharer R,Slover R,Klingensmith G

更新日期：2006-05-01 00:00:00

abstract：OBJECTIVE:To evaluate the temporal patterns of cardiometabolic multimorbidity (CM) and depression in White Caucasians (WCs) and African Americans (AAs) with early-onset type 2 diabetes and their impact on long-term atherosclerotic cardiovascular disease (ASCVD). RESEARCH DESIGN AND METHODS:From U.S. electronic medical...

journal_title：Diabetes care

authors： Dibato JE,Montvida O,Zaccardi F,Sargeant JA,Davies MJ,Khunti K,Paul SK

更新日期：2021-01-01 00:00:00

abstract：OBJECTIVE:To evaluate the incidence and relative risk of type 2 diabetes defined by the newly proposed HbA(1c) diagnostic criteria in groups categorized by different baseline HbA(1c) levels. RESEARCH DESIGN AND METHODS:Using data from the European Prospective Investigation of Cancer (EPIC)-Norfolk cohort with repeat H...

journal_title：Diabetes care

authors： Chamnan P,Simmons RK,Forouhi NG,Luben RN,Khaw KT,Wareham NJ,Griffin SJ

更新日期：2011-04-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to investigate alcohol consumption in relation to the incidence of type 2 diabetes. RESEARCH DESIGN AND METHODS:The study population consisted of 22778 twins of the Finnish Twin Cohort. This cohort was compiled in 1975 and includes all same-sexed twins born in Finland before 1958. I...

journal_title：Diabetes care

authors： Carlsson S,Hammar N,Grill V,Kaprio J

更新日期：2003-10-01 00:00:00

abstract：OBJECTIVE:To compare the effects of repaglinide, glipizide, and glibenclamide on insulin secretion and postprandial glucose after a single standard 500-kcal test meal. RESEARCH DESIGN AND METHODS:A total of 12 type 2 diabetic patients with early diabetes (mean HbA(1c) of 6.1%) and 12 matched control subjects were enro...

journal_title：Diabetes care

authors： Cozma LS,Luzio SD,Dunseath GJ,Langendorg KW,Pieber T,Owens DR

更新日期：2002-08-01 00:00:00

abstract：OBJECTIVE:Transforming growth factor (TGF)-beta1 is overexpressed in diabetes as a consequence of hyperglycemia and the creation of early glycated end products and may be responsible for the characteristic structural renal changes associated with diabetes. We sought to examine the role of both urinary and circulating T...

journal_title：Diabetes care

authors： Chaturvedi N,Schalkwijk CG,Abrahamian H,Fuller JH,Stehouwer CD,EURODIAB Prospective Complications Study Group.

更新日期：2002-12-01 00:00:00

abstract：OBJECTIVE:To evaluate the effectiveness of a telephone-delivered behavioral weight loss and physical activity intervention targeting Australian primary care patients with type 2 diabetes. RESEARCH DESIGN AND METHODS:Pragmatic randomized controlled trial of telephone counseling (n = 151) versus usual care (n = 151). Re...

journal_title：Diabetes care

authors： Eakin EG,Winkler EA,Dunstan DW,Healy GN,Owen N,Marshall AM,Graves N,Reeves MM

更新日期：2014-08-01 00:00:00

abstract：OBJECTIVE:The safety of dendritic cells to selectively suppress autoimmunity, especially in type 1 diabetes, has never been ascertained. We investigated the safety of autologous dendritic cells, stabilized into an immunosuppressive state, in established adult type 1 diabetic patients. RESEARCH DESIGN AND METHODS:A ran...

journal_title：Diabetes care

authors： Giannoukakis N,Phillips B,Finegold D,Harnaha J,Trucco M

更新日期：2011-09-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to elucidate whether serum adiponectin is associated with progression of diabetic nephropathy in type 1 diabetic patients. RESEARCH DESIGN AND METHODS:This was a prospective follow-up study as a part of the nationwide Finnish Diabetic Nephropathy Study; 1,330 type 1 diabetic pat...

journal_title：Diabetes care

authors： Saraheimo M,Forsblom C,Thorn L,Wadén J,Rosengård-Bärlund M,Heikkilä O,Hietala K,Gordin D,Frystyk J,Flyvbjerg A,Groop PH,FinnDiane Study Group.

更新日期：2008-06-01 00:00:00

abstract：OBJECTIVE:To compare a simple meal plan emphasizing healthy food choices with a traditional exchange-based meal plan in reducing HbA(1c) levels in urban African Americans with type 2 diabetes. RESEARCH DESIGN AND METHODS:A total of 648 patients with type 2 diabetes were randomized to receive instruction in either a he...

journal_title：Diabetes care

authors： Ziemer DC,Berkowitz KJ,Panayioto RM,El-Kebbi IM,Musey VC,Anderson LA,Wanko NS,Fowke ML,Brazier CW,Dunbar VG,Slocum W,Bacha GM,Gallina DL,Cook CB,Phillips LS

更新日期：2003-06-01 00:00:00

abstract：OBJECTIVE:To assess the relationship between the insertion (I)/deletion (D) polymorphism of the ACE gene and arterial distensibility in patients with type 2 diabetes and healthy control subjects. RESEARCH DESIGN AND METHODS:Aortic and carotid arterial distensibility were evaluated by measuring aortic pulse-wave veloci...

journal_title：Diabetes care

authors： Taniwaki H,Kawagishi T,Emoto M,Shoji T,Hosoi M,Kogawa K,Nishizawa Y,Morii H

更新日期：1999-11-01 00:00:00

abstract：:To assess the possible value of the use of high-purity pork insulin (HPPI) in the United States, the serum insulin (I), pancreatic polypeptide (PP), glucagon (G), and somatostatin (SRIF) antibody binding characteristics have been determined in 90 conventional insulin-treated diabetic subjects and related to their degr...

journal_title：Diabetes care

authors： Asplin CM,Hollander P,Pecoraro RE,Brodsky J,Palmer JP

更新日期：1981-05-01 00:00:00

abstract：OBJECTIVE:To evaluate the relationship between renal function, ambulatory blood pressure (AMBP), and glycemic control in microalbuminuric IDDM patients compared with normoalbuminuric patients. RESEARCH DESIGN AND METHODS:Nineteen male patients (age 33 +/- 6 years) with slight microalbuminuria (UAE 20-70 micrograms/min...

journal_title：Diabetes care

authors： Poulsen PL,Juhl B,Ebbehøj E,Klein F,Christiansen C,Mogensen CE

更新日期：1997-03-01 00:00:00

abstract：OBJECTIVE:Type 1 diabetes mellitus causes increased carotid intima-media thickness (IMT) in adults. We evaluated IMT in young subjects with type 1 diabetes. RESEARCH DESIGN AND METHODS:Participants with type 1 diabetes (N = 402) were matched to controls (N = 206) by age, sex, and race or ethnicity. Anthropometric and ...

journal_title：Diabetes care

authors： Urbina EM,Dabelea D,D'Agostino RB Jr,Shah AS,Dolan LM,Hamman RF,Daniels SR,Marcovina S,Wadwa RP

更新日期：2013-09-01 00:00:00

abstract：OBJECTIVE:We aimed to determine optimal blood pressure (BP) thresholds for minimizing coronary artery disease (CAD) risk in people with childhood-onset type 1 diabetes. RESEARCH DESIGN AND METHODS:The Pittsburgh Epidemiology of Diabetes Complications (EDC) Study participants without known CAD at baseline (n = 605) wer...

journal_title：Diabetes care

authors： Guo J,Brooks MM,Muldoon MF,Naimi AI,Orchard TJ,Costacou T

更新日期：2019-09-01 00:00:00

abstract：OBJECTIVE:We aimed to identify hemoglobin A1c (HbA1c)-associated genetic variants and examine their implications for glycemic status evaluated by HbA1c in U.S. Hispanics/Latinos with diverse genetic ancestries. RESEARCH DESIGN AND METHODS:We conducted a genome-wide association study (GWAS) of HbA1c in 9,636 U.S. Hispa...

journal_title：Diabetes care

authors： Moon JY,Louie TL,Jain D,Sofer T,Schurmann C,Below JE,Lai CQ,Aviles-Santa ML,Talavera GA,Smith CE,Petty LE,Bottinger EP,Chen YI,Taylor KD,Daviglus ML,Cai J,Wang T,Tucker KL,Ordovás JM,Hanis CL,Loos RJF,Schneiderm

更新日期：2019-09-01 00:00:00

abstract：OBJECTIVE:To determine whether low-glycemic index (GI) diets have clinical utility in overweight patients with non-insulin-dependent diabetes mellitus (NIDDM). RESEARCH DESIGN AND METHODS:Six patients with NIDDM were studied on both high- and low-GI diets of 6-wk duration with metabolic diets with a randomized crossov...

journal_title：Diabetes care

authors： Wolever TM,Jenkins DJ,Vuksan V,Jenkins AL,Wong GS,Josse RG

更新日期：1992-04-01 00:00:00

abstract：OBJECTIVE:Although the Diabetes Prevention Program (DPP) and the Finnish Diabetes Prevention Study (FDPS) demonstrated that weight loss from lifestyle change reduces type 2 diabetes incidence in patients with prediabetes, the translation into community settings has been difficult. The objective of this study is to repo...

journal_title：Diabetes care

authors： Katula JA,Vitolins MZ,Rosenberger EL,Blackwell CS,Morgan TM,Lawlor MS,Goff DC Jr

更新日期：2011-07-01 00:00:00

abstract：OBJECTIVE:To assess the performance of the Micral-Test II immunologic test strip for the detection of microalbuminuria, a multicenter evaluation in eight European study sites was performed. RESEARCH DESIGN AND METHODS:Using both the Micral-Test II test strip and the routine method for the determination of albumin conc...

journal_title：Diabetes care

authors： Mogensen CE,Viberti GC,Peheim E,Kutter D,Hasslacher C,Hofmann W,Renner R,Bojestig M,Poulsen PL,Scott G,Thoma J,Kuefer J,Nilsson B,Gambke B,Mueller P,Steinbiss J,Willamowski KD

更新日期：1997-11-01 00:00:00

abstract：OBJECTIVE:This study was performed to determine the net effects of euglycemia, resolution of renal failure, immunosuppressant drugs, and hyperinsulinemia on fasting lipid profiles of patients with renal failure and insulin-dependent diabetes mellitus (IDDM) after combined pancreas-kidney transplantation (PKT). RESEARC...

journal_title：Diabetes care

authors： Larsen JL,Stratta RJ,Ozaki CF,Taylor RJ,Miller SA,Duckworth WC

更新日期：1992-01-01 00:00:00

abstract：OBJECTIVE:To summarize the efficacy of metformin in reducing BMI and cardiometabolic risk in obese children and adolescents without diabetes. RESEARCH DESIGN AND METHODS:We performed a systematic review and meta-analysis of randomized controlled trials (RCTs). Double-blind RCTs of > or =6 months duration in obese subj...

journal_title：Diabetes care

authors： Park MH,Kinra S,Ward KJ,White B,Viner RM

更新日期：2009-09-01 00:00:00

abstract：:Developments in fetal and placental nutrition have highlighted the interaction of the placenta and fetal liver for the exchange and metabolism of nutrients. Of particular importance is the exchange of serine and glycine and their interconversion within these two organs and the exchange of glutamine and glutamate. Plac...

journal_title：Diabetes care

authors： Battaglia FC,Thureen PJ

更新日期：1998-08-01 00:00:00

abstract：:Neuropathic foot ulceration is a major medical and economic problem among diabetic patients, and the traditional treatment involves bed rest with complete freedom from weight-bearing. We have investigated the use of walking plaster casts in the management of seven diabetic patients with long-standing, chronic plantar ...

journal_title：Diabetes care

authors： Boulton AJ,Bowker JH,Gadia M,Lemerman R,Caswell K,Skyler JS,Sosenko JM

更新日期：1986-03-01 00:00:00

abstract：OBJECTIVE:To assess prospectively the effect of benchmarking on quality of primary care for patients with type 2 diabetes by using three major modifiable cardiovascular risk factors as critical quality indicators. RESEARCH DESIGN AND METHODS:Primary care physicians treating patients with type 2 diabetes in six Europea...

journal_title：Diabetes care

authors： Hermans MP,Elisaf M,Michel G,Muls E,Nobels F,Vandenberghe H,Brotons C,OPTIMISE International Steering Committee.

更新日期：2013-11-01 00:00:00

abstract：OBJECTIVE:To investigate the metabolic effects of metformin, as compared with placebo, in type 2 diabetic patients intensively treated with insulin. RESEARCH DESIGN AND METHODS:Metformin improves glycemic control in poorly controlled type 2 diabetic patients. Its effect in type 2 diabetic patients who are intensively ...

journal_title：Diabetes care

authors： Wulffelé MG,Kooy A,Lehert P,Bets D,Ogterop JC,Borger van der Burg B,Donker AJ,Stehouwer CD

更新日期：2002-12-01 00:00:00

abstract：OBJECTIVE:Hyperinsulinemia is often associated with several metabolic abnormalities and increased blood pressure, which are risk factors for cardiovascular disease. It has been hypothesized that insulin resistance may underlie all these features. However, recent data suggest that some links between insulin resistance a...

journal_title：Diabetes care

authors： Zanolin ME,Tosi F,Zoppini G,Castello R,Spiazzi G,Dorizzi R,Muggeo M,Moghetti P

更新日期：2006-02-01 00:00:00