Obstructive sleep apnea and diabetic nephropathy: a cohort study.

abstract：OBJECTIVE:To investigate the effect of parenteral insulin therapy on endogenous insulin secretion in the Diabetes Prevention Trial-Type 1 (DPT-1). RESEARCH DESIGN AND METHODS:In the parenteral insulin arm of DPT-1, subjects without diabetes at high risk of future type 1 diabetes randomized to active treatment received...

journal_title：Diabetes care

authors： Hao W,Greenbaum CJ,Krischer JP,Cuthbertson D,Marks JB,Palmer JP

更新日期：2015-05-01 00:00:00

abstract：OBJECTIVE:The goal was to assess the 1-year efficacy and safety of the addition of pioglitazone or metformin to existing sulfonylurea (SU) therapy in patients with inadequately controlled type 2 diabetes. RESEARCH DESIGN AND METHODS:In this multicenter, double-blind study, patients were randomized to receive either pi...

journal_title：Diabetes care

authors： Hanefeld M,Brunetti P,Schernthaner GH,Matthews DR,Charbonnel BH,QUARTET Study Group.

更新日期：2004-01-01 00:00:00

abstract：OBJECTIVE:To examine the association of stage of change with diet and exercise behaviors in response to a lifestyle intervention for Native Hawaiians (NHs). RESEARCH DESIGN AND METHODS:A family ('ohana) support lifestyle intervention was compared with a standard intervention in NHs with or at risk for diabetes in two ...

journal_title：Diabetes care

authors： Mau MK,Glanz K,Severino R,Grove JS,Johnson B,Curb JD

更新日期：2001-10-01 00:00:00

abstract：:We studied the accuracy of the Chemstrip bG and Glucometer systems in the self-monitoring of blood glucose by trained adolescents. The determinations were done at home with simultaneous collection of whole blood into capillary tubes (Sarstedt) which were later analyzed by a glucose-oxidase analyzer (Beckman Instrument...

journal_title：Diabetes care

authors： Schiffrin A,Desrosiers M,Belmonte M

更新日期：1983-03-01 00:00:00

abstract：OBJECTIVE:Individuals with impaired glucose tolerance (IGT) are at high risk for developing type 2 diabetes mellitus (T2DM). We examined which characteristics at baseline predicted the development of T2DM versus maintenance of IGT or conversion to normal glucose tolerance. RESEARCH DESIGN AND METHODS:We studied 228 su...

journal_title：Diabetes care

authors： Defronzo RA,Tripathy D,Schwenke DC,Banerji M,Bray GA,Buchanan TA,Clement SC,Henry RR,Kitabchi AE,Mudaliar S,Ratner RE,Stentz FB,Musi N,Reaven PD,Gastaldelli A,ACT NOW Study.

更新日期：2013-11-01 00:00:00

abstract：OBJECTIVE:To date no clinical trials have evaluated the role of dietary patterns on the incidence of microvascular diabetes complications. We hypothesized that a nutritional intervention based on the Mediterranean diet (MedDiet) would have greater protective effect on diabetic retinopathy and nephropathy than a low-fat...

journal_title：Diabetes care

authors： Díaz-López A,Babio N,Martínez-González MA,Corella D,Amor AJ,Fitó M,Estruch R,Arós F,Gómez-Gracia E,Fiol M,Lapetra J,Serra-Majem L,Basora J,Basterra-Gortari FJ,Zanon-Moreno V,Muñoz MÁ,Salas-Salvadó J,PREDIMED Study Inves

更新日期：2015-11-01 00:00:00

abstract：OBJECTIVE:To describe the changes in serum levels of calcitonin in liraglutide- and placebo-treated patients in the Liraglutide Effect and Action in Diabetes: Evaluation of Cardiovascular Outcome Results-A Long Term Evaluation (LEADER) trial over a 3.5-5-year period. RESEARCH DESIGN AND METHODS:Patients (n = 9,340) wi...

journal_title：Diabetes care

authors： Hegedüs L,Sherman SI,Tuttle RM,von Scholten BJ,Rasmussen S,Karsbøl JD,Daniels GH,LEADER Publication Committee on behalf of the LEADER Trial Investigators.

更新日期：2018-03-01 00:00:00

abstract：OBJECTIVE:The objective of the study was to assess the efficacy and safety of repaglinide compared with placebo in the treatment of patients with type 2 diabetes. RESEARCH DESIGN AND METHODS:This was a phase II multicenter, double-blind, placebo-controlled, randomized, dose-adjustment and maintenance trial. After scre...

journal_title：Diabetes care

authors： Goldberg RB,Einhorn D,Lucas CP,Rendell MS,Damsbo P,Huang WC,Strange P,Brodows RG

更新日期：1998-11-01 00:00:00

abstract：OBJECTIVE:Major depressive disorder (MDD) and type 2 diabetes have independent adverse effects on sexual functioning (SF). Bupropion (BU) reportedly has few sexual side effects, but its use in diabetes has not been studied. RESEARCH DESIGN AND METHODS:This article reports a planned secondary analysis of SF in 90 patie...

journal_title：Diabetes care

authors： Sayuk GS,Gott BM,Nix BD,Lustman PJ

更新日期：2011-02-01 00:00:00

abstract：:Glucose homeostasis is physiologically maintained by the balance between glucose production by the liver and glucose utilization by the peripheral tissues. Insulin controls hepatic glucose production and promotes glucose utilization by the skeletal muscle. In non-insulin-dependent diabetes mellitus (NIDDM), postabsorp...

journal_title：Diabetes care

authors： Consoli A

更新日期：1992-03-01 00:00:00

abstract：:We evaluated the epidemiology of diabetic ketoacidosis in the period 1960-1979. In Frederiksborg County, Denmark, the incidence of ketoacidosis at the county hospital increased from 60 per 100,000 in the period 1943-1963 to 120 per 100,000 in the period 1960-1979. In the investigation period we found an increasing inc...

journal_title：Diabetes care

authors： Ellemann K,Soerensen JN,Pedersen L,Edsberg B,Andersen OO

更新日期：1984-11-01 00:00:00

abstract：OBJECTIVE:Arterial stiffness occurs early in the atherosclerotic process; however, few data are available concerning risk factors for arterial stiffness in youth with diabetes. We identified factors associated with arterial stiffness in youth with diabetes and assessed the effects of these factors on the relationship b...

journal_title：Diabetes care

authors： Wadwa RP,Urbina EM,Anderson AM,Hamman RF,Dolan LM,Rodriguez BL,Daniels SR,Dabelea D,SEARCH Study Group.

更新日期：2010-04-01 00:00:00

abstract：OBJECTIVE:To investigate the association of folate and vitamin B12 in early pregnancy with gestational diabetes mellitus (GDM) risk. RESEARCH DESIGN AND METHODS:The data of this study were from a subcohort within the Shanghai Preconception Cohort Study. We included pregnancies with red blood cell (RBC) folate and vita...

journal_title：Diabetes care

authors： Chen X,Zhang Y,Chen H,Jiang Y,Wang Y,Wang D,Li M,Dou Y,Sun X,Huang G,Yan W

更新日期：2021-01-01 00:00:00

abstract：:The association of obesity with hypertension has been amply demonstrated in cross-sectional, longitudinal, and dietary-intervention studies, but the mechanisms remain enigmatic. Both conditions are independently characterized by similar metabolic alterations, i.e., glucose intolerance, dyslipoproteinemia, elevated ser...

journal_title：Diabetes care

authors： Modan M,Halkin H

更新日期：1991-06-01 00:00:00

abstract：OBJECTIVE:The objective of this study was to assess the association of inflammation with hyperglycemia (impaired fasting glucose [IFG]/impaired glucose tolerance [IGT]) and diabetes in older individuals. RESEARCH DESIGN AND METHODS:Baseline data from the Health, Aging and Body Composition study included 3,075 well-fun...

journal_title：Diabetes care

authors： de Rekeneire N,Peila R,Ding J,Colbert LH,Visser M,Shorr RI,Kritchevsky SB,Kuller LH,Strotmeyer ES,Schwartz AV,Vellas B,Harris TB

更新日期：2006-08-01 00:00:00

abstract：:Glycated hemoglobin targets have been given in guidelines for the last three decades, mostly without change at around 6.5-7.0% (47-53 mmol/mol). Personalization of such targets has also long been advocated, but often with little and inappropriate guidance. More recently some have suggested higher targets might be indi...

journal_title：Diabetes care

authors： Home P

更新日期：2019-09-01 00:00:00

abstract：:Malfunction of portable continuous subcutaneous insulin infusion (CSII) systems may result in either ketoacidosis or serious hypoglycemia. To determine the types and frequencies of infusion system failure and the resulting clinical consequences, we recorded their occurrences in a 1-yr prospective study of 127 patients...

journal_title：Diabetes care

authors： Mecklenburg RS,Guinn TS,Sannar CA,Blumenstein BA

更新日期：1986-07-01 00:00:00

abstract：:In this study, 18 type I (insulin-dependent) diabetic subjects aged 22-35 yr (mean age 29.3) and within 10 yr of diagnosis (mean 7.7) performed a battery of cognitive and psychomotor tasks under conditions of hypoglycemia (50 mg/dl), normoglycemia (100 mg/dl), and hyperglycemia (300 mg/dl). Blood glucose levels during...

journal_title：Diabetes care

authors： Hoffman RG,Speelman DJ,Hinnen DA,Conley KL,Guthrie RA,Knapp RK

更新日期：1989-03-01 00:00:00

abstract：OBJECTIVE:Antioxidant trials have not demonstrated efficacy in slowing cardiovascular disease but could not rule out benefit for specific patient subgroups. Antioxidant therapy reduces LDL oxidizability in haptoglobin 1 allele homozygotes (Hp 1-1), but not in individuals with the haptoglobin 2 allele (Hp 2-1 or Hp 2-2)...

journal_title：Diabetes care

authors： Levy AP,Friedenberg P,Lotan R,Ouyang P,Tripputi M,Higginson L,Cobb FR,Tardif JC,Bittner V,Howard BV

更新日期：2004-04-01 00:00:00

abstract：:To investigate vascular responses in insulin-dependent diabetic patients both with and without retinopathy, we have assessed vasodilation by forearm transcutaneous pO2 measurement after 10 min of ischemia produced by a sphygmomanometer cuff. Diabetic patients with proliferative retinopathy had a delayed vasodilatory r...

journal_title：Diabetes care

authors： Haitas B,Barnes A,Shogry ME,Weindling M,Rolfe P,Turner RC

更新日期：1984-01-01 00:00:00

abstract：OBJECTIVE:To investigate the effect of normal aging on the protective responses against hypoglycemia, in view of the fact that type II diabetes is primarily a disease of aging, and its treatment is associated with risk of hypoglycemia with cognitive impairment. RESEARCH DESIGN AND METHODS:Plasma glucose was lowered st...

journal_title：Diabetes care

authors： Matyka K,Evans M,Lomas J,Cranston I,Macdonald I,Amiel SA

更新日期：1997-02-01 00:00:00

abstract：OBJECTIVE:We sought to test the hypothesis that start of insulin glargine with sustained nightly insulin action results in changes in circulating concentrations of IGF-I and IGF binding proteins (IGFBPs) in adolescents with type 1 diabetes-changes that may support improvement of A1C. RESEARCH DESIGN AND METHODS:Twelve...

journal_title：Diabetes care

authors： Ekström K,Salemyr J,Zachrisson I,Carlsson-Skwirut C,Ortqvist E,Bang P

更新日期：2007-06-01 00:00:00

abstract：OBJECTIVE:To determine whether, after adjustment for glycemia and other selected covariates, hemoglobin A1c (HbA1c) differed among adults from six Hispanic/Latino heritage groups (Central American, Cuban, Dominican, Mexican, Puerto Rican, and South American) and between Hispanic/Latino and non-Hispanic white adults wit...

journal_title：Diabetes care

authors： Avilés-Santa ML,Hsu LL,Arredondo M,Menke A,Werner E,Thyagarajan B,Heiss G,Teng Y,Schneiderman N,Giachello AL,Gallo LC,Talavera GA,Cowie CC

更新日期：2016-06-01 00:00:00

abstract：OBJECTIVE:To determine whether reducing triglyceride concentrations in humans reduces serum insulin levels and consider the implications of this for the insulin resistance of hypertriglyceridemia. RESEARCH DESIGN AND METHODS:Insulin and glucose levels were determined during an oral glucose tolerance test (OGTT) in 14 ...

journal_title：Diabetes care

authors： Steiner G

更新日期：1991-11-01 00:00:00

abstract：:Stress is a potential contributor to chronic hyperglycemia in diabetes. Stress has long been shown to have major effects on metabolic activity. Energy mobilization is a primary result of the fight or flight response. Stress stimulates the release of various hormones, which can result in elevated blood glucose levels. ...

journal_title：Diabetes care

authors： Surwit RS,Schneider MS,Feinglos MN

更新日期：1992-10-01 00:00:00

abstract：:This commentary/review briefly considers the diverse criteria recommended for classification of overweight infants. Macrosomia continues to be a vexing problem for both obstetricians and pediatricians. Among the various techniques possible for use in assessing body composition, none are more practical than body weight...

journal_title：Diabetes care

authors： Schwartz R,Teramo KA

更新日期：1999-07-01 00:00:00

abstract：OBJECTIVE:To compare the efficacy and safety of two doses of once-weekly dulaglutide, a glucagon-like peptide 1 receptor agonist, to sitagliptin in uncontrolled, metformin-treated patients with type 2 diabetes. The primary objective was to compare (for noninferiority and then superiority) dulaglutide 1.5 mg versus sita...

journal_title：Diabetes care

authors： Nauck M,Weinstock RS,Umpierrez GE,Guerci B,Skrivanek Z,Milicevic Z

更新日期：2014-08-01 00:00:00

abstract：OBJECTIVE:Although initially effective, sulfonylureas are associated with poor glycemic durability, weight gain, and hypoglycemia. Dapagliflozin, a selective inhibitor of sodium-glucose cotransporter 2 (SGLT2), reduces hyperglycemia by increasing urinary glucose excretion independent of insulin and may cause fewer of t...

journal_title：Diabetes care

authors： Nauck MA,Del Prato S,Meier JJ,Durán-García S,Rohwedder K,Elze M,Parikh SJ

更新日期：2011-09-01 00:00:00

abstract：OBJECTIVE:To evaluate temporal trends in rates of initial lower extremity amputation (ILEA) among patients with diabetes in the Veterans Health Administration (VHA). RESEARCH DESIGN AND METHODS:Retrospective administrative data analysis of VHA clinic users with diabetes in fiscal years (FY) 2000 to 2004 (1 October 199...

journal_title：Diabetes care

authors： Tseng CL,Rajan M,Miller DR,Lafrance JP,Pogach L

更新日期：2011-05-01 00:00:00

abstract：OBJECTIVE:To determine whether the severity of retinopathy is higher in a group of NIDDM patients with sBP greater than or equal to 140 mmHg compared with NIDDM patients with sBP less than 140 mmHg. RESEARCH DESIGN AND METHODS:Ophthalmoscopy and FAG were conducted among a group of NIDDM patients with either a sBP abov...

journal_title：Diabetes care

authors： Cignarelli M,De Cicco ML,Damato A,Paternostro A,Pagliarini S,Santoro S,Cardia L,De Pergola G,Giorgino R

更新日期：1992-08-01 00:00:00