Hyperinsulinemia or increased sympathetic drive as links for obesity and hypertension.

abstract：:Seventeen diabetic subjects requiring insulin and who exhibited glycemic stability over a 9-12-mo control period received 5 g of pectin with each meal and at bedtime for 3 mo. Hemoglobin A1c (HbA1c) and glycosylated serum protein were measured in each patient on multiple occasions to assess glycemic control. No clear-...

journal_title：Diabetes care

authors： Gardner DF,Schwartz L,Krista M,Merimee TJ

更新日期：1984-03-01 00:00:00

abstract：OBJECTIVE:Poorer glycemic control in type 1 diabetes may alter N-glycosylation patterns on circulating glycoproteins, and these alterations may be linked with diabetic kidney disease (DKD). We investigated associations between N-glycans and glycemic control and renal function in type 1 diabetes. RESEARCH DESIGN AND ME...

journal_title：Diabetes care

authors： Bermingham ML,Colombo M,McGurnaghan SJ,Blackbourn LAK,Vučković F,Pučić Baković M,Trbojević-Akmačić I,Lauc G,Agakov F,Agakova AS,Hayward C,Klarić L,Palmer CNA,Petrie JR,Chalmers J,Collier A,Green F,Lindsay RS,Macrury S

更新日期：2018-01-01 00:00:00

abstract：OBJECTIVE:Advanced glycation end products (AGEs) are a risk factor for diabetic complications. We have developed an assay method for N-(carboxymethyl)valine (CMV) of the hemoglobin (CMV-Hb), which is an AGE generated from HbA1c. Herein we describe the clinical utility of CMV-Hb measurement for the diagnosis of diabetic...

journal_title：Diabetes care

authors： Uchimura T,Nakano K,Hashiguchi T,Iwamoto H,Miura K,Yoshimura Y,Hanyu N,Hirata K,Imakuma M,Motomiya Y,Maruyama I

更新日期：2001-05-01 00:00:00

abstract：OBJECTIVE:To date no clinical trials have evaluated the role of dietary patterns on the incidence of microvascular diabetes complications. We hypothesized that a nutritional intervention based on the Mediterranean diet (MedDiet) would have greater protective effect on diabetic retinopathy and nephropathy than a low-fat...

journal_title：Diabetes care

authors： Díaz-López A,Babio N,Martínez-González MA,Corella D,Amor AJ,Fitó M,Estruch R,Arós F,Gómez-Gracia E,Fiol M,Lapetra J,Serra-Majem L,Basora J,Basterra-Gortari FJ,Zanon-Moreno V,Muñoz MÁ,Salas-Salvadó J,PREDIMED Study Inves

更新日期：2015-11-01 00:00:00

abstract：:Diabetic retinopathy is the leading cause of visual impairment and preventable blindness, and represents a significant socioeconomic cost for health care systems worldwide. Therefore, new approaches beyond current standards of diabetes care are needed. Based on the crucial pathogenic role of vascular endothelial growt...

journal_title：Diabetes care

authors： Simó R,Sundstrom JM,Antonetti DA

更新日期：2014-04-01 00:00:00

abstract：OBJECTIVE:To examine whether the association between gestational diabetes mellitus (GDM) and BMI category varies by racial/ethnic group. RESEARCH DESIGN AND METHODS:In a cohort of 123,040 women without recognized pregravid diabetes who delivered babies between 1995 and 2006 at Kaiser Permanente of Northern California,...

journal_title：Diabetes care

authors： Hedderson M,Ehrlich S,Sridhar S,Darbinian J,Moore S,Ferrara A

更新日期：2012-07-01 00:00:00

abstract：OBJECTIVE:The purpose of this article was to compare the effects of cod protein to those of other animal proteins on insulin sensitivity in insulin-resistant human subjects. RESEARCH DESIGN AND METHODS:Insulin sensitivity (M/I) was assessed using a hyperinsulinemic-euglycemic clamp in 19 insulin-resistant subjects fed...

journal_title：Diabetes care

authors： Ouellet V,Marois J,Weisnagel SJ,Jacques H

更新日期：2007-11-01 00:00:00

abstract：OBJECTIVE:Monozygotic twins are usually discordant (only one twin affected) for type 1 diabetes. Discordance for disease between such twins implies a role for nongenetically determined factors but could also be influenced by a decreased load of diabetes susceptibility genes. The aim of this study was to determine wheth...

journal_title：Diabetes care

authors： Metcalfe KA,Hitman GA,Rowe RE,Hawa M,Huang X,Stewart T,Leslie RD

更新日期：2001-05-01 00:00:00

abstract：:Glycosylated serum protein (GSP) and glycosylated hemoglobin (GHb) were measured in 263 insulin-dependent and 41 non-insulin-dependent diabetic subjects. Both indices provided useful information in type II diabetes, but were extremely poor in judging control in type I diabetes. In both groups, there was poor correlati...

journal_title：Diabetes care

authors： Mehl TD,Wenzel SE,Russell B,Gardner D,Merimee TJ

更新日期：1983-01-01 00:00:00

abstract：OBJECTIVE:Previous reviews of the effect of oral antidiabetic (OAD) agents on A1C levels summarized studies with varying designs and methodological approaches. Using predetermined methodological criteria, we evaluated the effect of OAD agents on A1C levels. RESEARCH DESIGN AND METHODS:The Excerpta Medica (EMBASE), the...

journal_title：Diabetes care

authors： Sherifali D,Nerenberg K,Pullenayegum E,Cheng JE,Gerstein HC

更新日期：2010-08-01 00:00:00

abstract：OBJECTIVE:Therapies with metformin, sulfonylureas, or insulin improve glycemic control in the short term but do not prevent progressive islet beta-cell failure or long-term deterioration in glycemia. Our goal was to evaluate, in patients recently diagnosed with type 2 diabetes (<3 years), the long-term efficacy of mono...

journal_title：Diabetes care

authors： Viberti G,Kahn SE,Greene DA,Herman WH,Zinman B,Holman RR,Haffner SM,Levy D,Lachin JM,Berry RA,Heise MA,Jones NP,Freed MI

更新日期：2002-10-01 00:00:00

abstract：OBJECTIVE:To determine whether low-glycemic index (GI) diets have clinical utility in overweight patients with non-insulin-dependent diabetes mellitus (NIDDM). RESEARCH DESIGN AND METHODS:Six patients with NIDDM were studied on both high- and low-GI diets of 6-wk duration with metabolic diets with a randomized crossov...

journal_title：Diabetes care

authors： Wolever TM,Jenkins DJ,Vuksan V,Jenkins AL,Wong GS,Josse RG

更新日期：1992-04-01 00:00:00

abstract：OBJECTIVE:Patients with diabetes have a higher case fatality rate in myocardial infarction (MI) or stroke than those without diabetes: that is, MI and stroke are more often fatal if diabetes is present. We investigated whether the risk of MI or stroke being fatal in type 2 diabetes can be estimated using information av...

journal_title：Diabetes care

authors： Stevens RJ,Coleman RL,Adler AI,Stratton IM,Matthews DR,Holman RR

更新日期：2004-01-01 00:00:00

abstract：OBJECTIVE:The objective of this study was to assess the association of inflammation with hyperglycemia (impaired fasting glucose [IFG]/impaired glucose tolerance [IGT]) and diabetes in older individuals. RESEARCH DESIGN AND METHODS:Baseline data from the Health, Aging and Body Composition study included 3,075 well-fun...

journal_title：Diabetes care

authors： de Rekeneire N,Peila R,Ding J,Colbert LH,Visser M,Shorr RI,Kritchevsky SB,Kuller LH,Strotmeyer ES,Schwartz AV,Vellas B,Harris TB

更新日期：2006-08-01 00:00:00

abstract：OBJECTIVE:To test whether diabetic polyneuropathies (DPNs), retinopathy, or nephropathy is more prevalent in subjects with impaired glycemia (IG) (abnormality of impaired fasting glucose [IFG], impaired glucose tolerance [IGT], or impaired HbA(1c) [IA1C]) than in healthy subjects (non-IG). RESEARCH DESIGN AND METHODS:...

journal_title：Diabetes care

authors： Dyck PJ,Clark VM,Overland CJ,Davies JL,Pach JM,Dyck PJ,Klein CJ,Rizza RA,Melton LJ 3rd,Carter RE,Klein R,Litchy WJ

更新日期：2012-03-01 00:00:00

abstract：:Chemical test strips for estimating blood glucose have been shown to be reliable, rapid, and convenient when properly used. This study compares a new product, the Ames Visidex (Miles Laboratories, Elkhart, Indiana), and an established product, the Bio-Dynamics Chemstrip bG (Boehringer-Mannheim, Indianapolis, Indiana) ...

journal_title：Diabetes care

authors： Frindik JP,Kassner DA,Pirkle DA,Kemp SF,Hoff C

更新日期：1983-11-01 00:00:00

abstract：OBJECTIVE:People with diabetes have an increased risk of coronary artery disease (CAD). An unanswered question is what portion of CAD can be attributed to insulin resistance, related metabolic variables, and other known CAD risk factors. RESEARCH DESIGN AND METHODS:The Archimedes model was used to estimate the proport...

journal_title：Diabetes care

authors： Eddy D,Schlessinger L,Kahn R,Peskin B,Schiebinger R

更新日期：2009-02-01 00:00:00

abstract：OBJECTIVE:To characterize renal impairment associated with diabetes in older adults by serum markers of glomerular filtration rate and microalbuminuria tests. RESEARCH DESIGN AND METHODS:The study population consisted of 187 diabetic and 1,073 nondiabetic subjects (age range 64-100 years) participating in a cross-sect...

journal_title：Diabetes care

authors： Wasén E,Isoaho R,Mattila K,Vahlberg T,Kivelä SL,Irjala K

更新日期：2004-11-01 00:00:00

abstract：OBJECTIVE:Type 1 diabetes has been associated with factors related to welfare and social class. During the past decade, Lithuania has experienced a transition period, leading to dramatic changes in the socioeconomic structure of the society. RESEARCH DESIGN AND METHODS:Incidence in the group aged 0-39 years by urban-r...

journal_title：Diabetes care

authors： Pundziute-Lyckå A,Urbonaite B,Ostrauskas R,Zalinkevicius R,Dahlquist GG

更新日期：2003-03-01 00:00:00

abstract：:Borderline hypertension, a condition in which the blood pressure oscillates between normal and high values, is a predictor of future more severe hypertension. Pathophysiologically, borderline hypertension is different from established hypertension. A large proportion of such patients have elevated cardiac output and a...

journal_title：Diabetes care

authors： Julius S

更新日期：1991-03-01 00:00:00

abstract：OBJECTIVE:Left ventricular remodeling occurs immediately after MI, involving structural changes in noninfarcted segment. However, the residual left ventricular pump function in NIDDM patients after acute MI has not been clarified. The purpose of this study was to evaluate the difference in the process of left ventricul...

journal_title：Diabetes care

authors： Iwasaka T,Takahashi N,Nakamura S,Sugiura T,Tarumi N,Kimura Y,Okubo N,Taniguchi H,Matsui Y,Inada M

更新日期：1992-11-01 00:00:00

abstract：OBJECTIVE:Repaglinide is a newly developed oral blood glucose-lowering agent that exerts its effect by stimulating insulin secretion. This multicenter study was designed to compare the efficacy and safety of this drug with glyburide in a 1-year randomized double-blind study of outpatients with type 2 diabetes. RESEARC...

journal_title：Diabetes care

authors： Wolffenbuttel BH,Landgraf R

更新日期：1999-03-01 00:00:00

abstract：OBJECTIVE:To review the published literature and perform a meta-analysis summarizing the evidence in support of an inverse association between type 1 diabetes and the atopic disorders: asthma, eczema, and allergic rhinitis in children. RESEARCH DESIGN AND METHODS:MEDLINE, Web of Science, and PubMed were searched to id...

journal_title：Diabetes care

authors： Cardwell CR,Shields MD,Carson DJ,Patterson CC

更新日期：2003-09-01 00:00:00

abstract：OBJECTIVE:Assessing updated incidence of type 1 diabetes in 0- to 14-year-old children in Liguria, a Northwest region of Italy. RESEARCH DESIGN AND METHODS:Incident cases were recorded prospectively from 1989 to 1998. Incidence rates (IRs) were standardized to the 1999 world population using the direct method. The ind...

journal_title：Diabetes care

authors： Cotellessa M,Barbieri P,Mazzella M,Bonassi S,Minicucci L,Lorini R

更新日期：2003-06-01 00:00:00

abstract：OBJECTIVE:To determine the frequency of hypoglycemia in patients with type I diabetes and impaired awareness of hypoglycemia by prospective assessment. RESEARCH DESIGN AND METHODS:A prospective study was undertaken for 12 months in 60 patients with type I diabetes: 29 had impaired awareness of hypoglycemia and 31 reta...

journal_title：Diabetes care

authors： Gold AE,MacLeod KM,Frier BM

更新日期：1994-07-01 00:00:00

abstract：OBJECTIVE:The prevalence of the metabolic syndrome, a potent risk factor for cardiovascular diseases (CVDs), has not been adequately explored in older individuals. Moreover, two sets of criteria have been proposed for the definition of metabolic syndrome, one by the World Health Organization (WHO) and one by the Nation...

journal_title：Diabetes care

authors： Scuteri A,Najjar SS,Morrell CH,Lakatta EG,Cardiovascular Health Study.

更新日期：2005-04-01 00:00:00

abstract：OBJECTIVE:Regular physical activity (PA) reduces the risk of developing type 2 diabetes, and different subtypes of dysglycemia have shown different associations with PA. To better understand the associations of PA and glucose homeostasis, we examined the association of objectively measured PA energy expenditure (PAEE) ...

journal_title：Diabetes care

authors： Hansen AL,Carstensen B,Helge JW,Johansen NB,Gram B,Christiansen JS,Brage S,Lauritzen T,Jørgensen ME,Aadahl M,Witte DR,ADDITION-Denmark Steering Committee.

更新日期：2013-10-01 00:00:00

abstract：OBJECTIVE:To study the effect of birth weight on risk of type 2 diabetes in the schoolchildren in Taiwan. RESEARCH DESIGN AND METHODS:From 1992 to 1997, all schoolchildren aged 6-18 years were screened for diabetes in Taiwan Province. This cohort consisted of 1,966 patients with diabetes and 1,780 randomly selected su...

journal_title：Diabetes care

authors： Wei JN,Sung FC,Li CY,Chang CH,Lin RS,Lin CC,Chiang CC,Chuang LM

更新日期：2003-02-01 00:00:00

abstract：OBJECTIVE:To quantify the incremental survival benefit of the pancreas allograft in simultaneous pancreas-kidney (SPK) transplant recipients. RESEARCH DESIGN AND METHODS:Data from the national transplant database from 2000 to 2007 were analyzed. SPK recipients who had functioning allografts to 1-year post transplant (...

journal_title：Diabetes care

authors： Salvalaggio PR,Dzebisashvili N,Pinsky B,Schnitzler MA,Burroughs TE,Graff R,Axelrod DA,Brennan DC,Lentine KL

更新日期：2009-04-01 00:00:00

abstract：OBJECTIVE:To evaluate the association between the C242T polymorphism of the p22 phox gene, an essential component of NAD(P)H oxidase in the vasculature, with intima-media thickness (IMT) of the carotid artery and risk factors for atherosclerosis in type 2 diabetic subjects. RESEARCH DESIGN AND METHODS:C242T polymorphi...

journal_title：Diabetes care

authors： Hayaishi-Okano R,Yamasaki Y,Kajimoto Y,Sakamoto K,Ohtoshi K,Katakami N,Kawamori D,Miyatsuka T,Hatazaki M,Hazama Y,Hori M

更新日期：2003-02-01 00:00:00