Beneficial effect of low-glycemic index diet in overweight NIDDM subjects.

Abstract:

OBJECTIVE:To determine whether low-glycemic index (GI) diets have clinical utility in overweight patients with non-insulin-dependent diabetes mellitus (NIDDM). RESEARCH DESIGN AND METHODS:Six patients with NIDDM were studied on both high- and low-GI diets of 6-wk duration with metabolic diets with a randomized crossover design. Both diets were of similar composition (57% carbohydrate, 23% fat, and 34 g/day dietary fiber), but the low-GI diet had a GI of 58 compared with 86 for the high-GI diet. RESULTS:Small and similar amounts of weight were lost on both diets: 2.5 kg on high-GI diet and 1.8 kg on low-GI diet. On the low-GI diet, the mean level of serum fructosamine, as an index of overall blood glucose control, was lower than on the high-GI diet by 8% (P less than 0.05), and total serum cholesterol was lower by 7% (P less than 0.01). CONCLUSIONS:In overweight patients with NIDDM, reducing diet GI improves overall blood glucose and lipid control.

journal_name

Diabetes Care

journal_title

Diabetes care

authors

Wolever TM,Jenkins DJ,Vuksan V,Jenkins AL,Wong GS,Josse RG

doi

10.2337/diacare.15.4.562

subject

Has Abstract

pub_date

1992-04-01 00:00:00

pages

562-4

issue

4

eissn

0149-5992

issn

1935-5548

journal_volume

15

pub_type

临床试验,杂志文章,随机对照试验
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