Renal impairment associated with diabetes in the elderly.

abstract：:Limited weight loss following jejunoileal bypass in 24 diabetic persons who were still distinctly overweight five to ten months after a mean weight decrease of 78 lbs. was accompanied by a return of normal fasting glucose and insulin levels, normal insulin responses, and a decrease in glucose intolerance. The glucose ...

journal_title：Diabetes care

authors： Ahmad U,Danowski TS,Nolan S,Stephan T,Sunder JH,Bahl VK

更新日期：1978-05-01 00:00:00

abstract：OBJECTIVE:The role of adiponectin in the natural history of diabetes is not well characterized. We set out to characterize prediagnosis trajectories of adiponectin in individuals who develop type 2 diabetes. RESEARCH DESIGN AND METHODS:In a case-cohort study (335 incident diabetes case and 2,474 noncase subjects) nest...

journal_title：Diabetes care

authors： Tabák AG,Carstensen M,Witte DR,Brunner EJ,Shipley MJ,Jokela M,Roden M,Kivimäki M,Herder C

更新日期：2012-12-01 00:00:00

abstract：OBJECTIVE:Sulfonylureas block the activation of vascular potassium-dependent ATP channels and impair the vasodilating response to ischcmia in nondiabetic individuals, but it is not know whether this occurs in type 2 diabetic patients under chronic treatment with these drugs. Glimepiride, a new sulfonylurea, apparently ...

journal_title：Diabetes care

authors： Spallarossa P,Schiavo M,Rossettin P,Cordone S,Olivotti L,Cordera R,Brunelli C

更新日期：2001-04-01 00:00:00

abstract：OBJECTIVE:Mild demyelination may contribute more to the pathophysiology of nerve fiber injury in diabetic sensorimotor polyneuropathy (DSP) than previously thought. We investigated the clinical and electrodiagnostic classifications of nerve injury in diabetic patients to detect evidence of conduction slowing in DSP. R...

journal_title：Diabetes care

authors： Dunnigan SK,Ebadi H,Breiner A,Katzberg HD,Lovblom LE,Perkins BA,Bril V

更新日期：2013-11-01 00:00:00

abstract：OBJECTIVE:To conduct a systematic review of the published literature on the efficacy and safety of herbal therapies and vitamin/mineral supplements for glucose control in patients with diabetes. RESEARCH DESIGN AND METHODS:We conducted an electronic literature search of MEDLINE, OLDMEDLINE, Cochrane Library Database, ...

journal_title：Diabetes care

authors： Yeh GY,Eisenberg DM,Kaptchuk TJ,Phillips RS

更新日期：2003-04-01 00:00:00

abstract：OBJECTIVE:Impaired awareness of hypoglycemia (IAH) and recurrent severe hypoglycemia (RSH) remain problematic for people with type 1 diabetes (T1D), despite major therapeutic advances. We explored beliefs around hypo- and hyperglycemia in adults with T1D with, and without, IAH and RSH. RESEARCH DESIGN AND METHODS:A cr...

journal_title：Diabetes care

authors： Cook AJ,DuBose SN,Foster N,Smith EL,Wu M,Margiotta G,Rickels MR,Speight J,de Zoysa N,Amiel SA

更新日期：2019-10-01 00:00:00

abstract：:In children with insulin-dependent diabetes mellitus (IDDM), deterioration in metabolic control frequently occurs during early adolescence. To prevent this predictable increase in blood glucose levels, we randomly assigned young adolescents with IDDM to an intervention based on problem solving with self-monitoring of ...

journal_title：Diabetes care

authors： Anderson BJ,Wolf FM,Burkhart MT,Cornell RG,Bacon GE

更新日期：1989-03-01 00:00:00

abstract：OBJECTIVE:To determine whether increasing doses (amounts) of beta-glucan present in an extruded breakfast cereal affect the glycemic and insulinemic responses in eight NIDDM subjects, compared with the same responses after a continental breakfast (bread, milk, cheese, ham). RESEARCH DESIGN AND METHODS:Breakfast cereal...

journal_title：Diabetes care

authors： Tappy L,Gügolz E,Würsch P

更新日期：1996-08-01 00:00:00

abstract：OBJECTIVE:To estimate the health-related quality of life (HRQOL) and treatment satisfaction for patients with type 2 diabetes in the Netherlands and to examine which patient characteristics are associated with quality of life and treatment satisfaction. RESEARCH DESIGN AND METHODS:For a sample of 1,348 type 2 diabetes...

journal_title：Diabetes care

authors： Redekop WK,Koopmanschap MA,Stolk RP,Rutten GE,Wolffenbuttel BH,Niessen LW

更新日期：2002-03-01 00:00:00

abstract：OBJECTIVE:Proteoglycan metabolism is altered in diabetic patients. The xylosyltransferases (XTs) are the initial and rate-limiting enzymes in the biosynthesis of the glycosaminoglycan chains in proteoglycans. Here, we analyzed whether the changed proteoglycan metabolism leads to altered serum XT levels in diabetic pati...

journal_title：Diabetes care

authors： Götting C,Kuhn J,Kleesiek K

更新日期：2008-10-01 00:00:00

abstract：OBJECTIVE:Of patients who are prescribed metformin, 10-30% have evidence of reduced vitamin B12 absorption. B12-intrinsic factor complex uptake by ileal cell surface receptors is known to be a process dependent on calcium availability Metformin affects calcium-dependent membrane action. The objective of this study was ...

journal_title：Diabetes care

authors： Bauman WA,Shaw S,Jayatilleke E,Spungen AM,Herbert V

更新日期：2000-09-01 00:00:00

abstract：OBJECTIVE:The monosaccharides resulting from the digestion of ingested carbohydrates are glucose, fructose, and galactose. Of these three monosaccharides, only ingested glucose resulted in a large increase in the plasma glucose concentration. Fructose (Metabolism 41:510-517, 1992) and galactose (Metabolism 42:1560-1567...

journal_title：Diabetes care

authors： Gannon MC,Nuttall FQ,Westphal SA,Fang S,Ercan-Fang N

更新日期：1998-10-01 00:00:00

abstract：OBJECTIVE:Global usage of bariatric surgery has been dictated for the past quarter century by National Institutes of Health recommendations restricting these operations to individuals with a BMI ≥35 kg/m(2). Strong evidence now demonstrates that bariatric procedures markedly improve or cause remission of type 2 diabete...

journal_title：Diabetes care

authors： Cummings DE,Cohen RV

更新日期：2016-06-01 00:00:00

abstract：OBJECTIVE:High birth weight is a risk factor for neonatal complications. It is not known if the risk differs with body proportionality. The primary aim of this study was to determine the risk of adverse pregnancy outcome in relation to body proportionality in large-for-gestational-age (LGA) infants stratified by matern...

journal_title：Diabetes care

authors： Persson M,Fadl H,Hanson U,Pasupathy D

更新日期：2013-11-01 00:00:00

abstract：OBJECTIVE:To provide a description of the clinical characteristics that distinguish individuals who withhold insulin for weight control from those who do not. Some individuals with insulin-dependent diabetes mellitus (IDDM) control their weight by withholding insulin and purging excessive calories. This process places ...

journal_title：Diabetes care

authors： Biggs MM,Basco MR,Patterson G,Raskin P

更新日期：1994-10-01 00:00:00

abstract：OBJECTIVE:Reduced heart rate variability (HRV) and increased heart rate (HR) have been associated with cardiovascular mortality. Glucagon-like peptide 1 receptor agonists (GLP-1 RAs) increase HR, and studies have suggested that they may reduce HRV. We examined the effect of the GLP-1 RA liraglutide on HRV and diurnal v...

journal_title：Diabetes care

authors： Kumarathurai P,Anholm C,Larsen BS,Olsen RH,Madsbad S,Kristiansen O,Nielsen OW,Haugaard SB,Sajadieh A

更新日期：2017-01-01 00:00:00

abstract：:Because recent knowledge indicates that the distribution of fat deposits in men may be a better predictor of cardiovascular disease than the degree of obesity alone, some risk factors for atherosclerosis were evaluated in 51 middle-aged men with non-insulin-dependent diabetes mellitus. Abdominal adiposity (waist/hip r...

journal_title：Diabetes care

authors： Van Gaal L,Rillaerts E,Creten W,De Leeuw I

更新日期：1988-02-01 00:00:00

abstract：OBJECTIVE:The relative roles of insulin resistance and beta-cell dysfunction in the pathogenesis of impaired glucose tolerance (IGT) and type 2 diabetes are debated. First-degree relatives of individuals with type 2 diabetes are at increased risk of developing hyperglycemia. RESEARCH DESIGN AND METHODS:We evaluated th...

journal_title：Diabetes care

authors： Cnop M,Vidal J,Hull RL,Utzschneider KM,Carr DB,Schraw T,Scherer PE,Boyko EJ,Fujimoto WY,Kahn SE

更新日期：2007-03-01 00:00:00

abstract：:This study compares the utility of nonenzymatically glycosylated serum proteins (lys-GSP) to glycosylated hemoglobins (HbA1a-c) as control indices of glucose homeostasis in patients with IDDM. The diagnostic value of lys-GSP was also examined in patients with non-insulin-dependent diabetes mellitus, in subjects with i...

journal_title：Diabetes care

authors： Schleicher ED,Gerbitz KD,Dolhofer R,Reindl E,Wieland OH,Edelmann E,Haslbeck M,Kemmler W,Walter H,Mehnert H

更新日期：1984-11-01 00:00:00

abstract：OBJECTIVE:To determine if nephropathy in NIDDM is associated with cellular markers for hypertension. RESEARCH DESIGN AND METHODS:We compared 11 patients with clinical diabetic nephropathy with 15 control subjects with no diabetic nephropathy. The patients were white and had had NIDDM for > or = 9 yr and serum creatini...

journal_title：Diabetes care

authors： Herman WH,Prior DE,Yassine MD,Weder AB

更新日期：1993-05-01 00:00:00

abstract：OBJECTIVE:To examine mortality rates and causes of death among subjects diagnosed with type 1 diabetes aged

journal_title：Diabetes care

authors： Feltbower RG,Bodansky HJ,Patterson CC,Parslow RC,Stephenson CR,Reynolds C,McKinney PA

更新日期：2008-05-01 00:00:00

abstract：OBJECTIVE:To examine patterns of sugar-sweetened beverage (SSB) consumption among U.S. adults with type 2 diabetes in 2003-2006. RESEARCH DESIGN AND METHODS:We analyzed 24-h dietary recall data from the National Health and Nutrition Examination Survey 2003-2006 to estimate SSB consumption levels among 1,090 adults (ag...

journal_title：Diabetes care

authors： Bleich SN,Wang YC

更新日期：2011-03-01 00:00:00

abstract：:A survey of the entire population of Israel revealed 392 newly diagnosed type I diabetic children and adolescents aged 0-20 for the period of 1975-80. The mean annual age specific incidence of type I (insulin-dependent) diabetes mellitus was 3.8/10(5) for the age group 0-14 yr and 4.2/10(5) for the age group 0-20 yr. ...

journal_title：Diabetes care

authors： Laron ZV,Karp M,Modan M

更新日期：1985-09-01 00:00:00

abstract：OBJECTIVES:Obesity is a common condition in type 2 diabetic patients. Treating obesity may enhance hypoglycemic treatment and contribute to the reduction of long-term microvascular and macrovascular complications. Orlistat reduces cardiovascular risk factors in obese type 2 diabetic patients. The objectives of this stu...

journal_title：Diabetes care

authors： Lamotte M,Annemans L,Lefever A,Nechelput M,Masure J

更新日期：2002-02-01 00:00:00

abstract：:A diabetic woman presented with diabetic ketoacidosis after demonstrating immediate-type hypersensitivity to heterologous insulin. She had had interrupted insulin therapy in the past. Insulin requirements during the course of treatment for the acidosis suggested marked resistance, with 50,000 U of insulin needed in th...

journal_title：Diabetes care

authors： Ross JM,Murali MR,DeLara TC,Cheron RG

更新日期：1984-05-01 00:00:00

abstract：OBJECTIVE:To assess the effects of empagliflozin, a selective sodium-glucose cotransporter 2 (SGLT2) inhibitor, on broad biological systems through proteomics. RESEARCH DESIGN AND METHODS:Aptamer-based proteomics was used to quantify 3,713 proteins in 144 paired plasma samples obtained from 72 participants across the ...

journal_title：Diabetes care

authors： Ferrannini E,Murthy AC,Lee YH,Muscelli E,Weiss S,Ostroff RM,Sattar N,Williams SA,Ganz P

更新日期：2020-09-01 00:00:00

abstract：OBJECTIVE:We assessed the association between different blood lipid measures and risk of fatal/nonfatal coronary heart disease (CHD). RESEARCH DESIGN AND METHODS:We conducted an observational study of patients with type 2 diabetes from the Swedish National Diabetes Register. Baseline LDL cholesterol, non-HDL cholester...

journal_title：Diabetes care

authors： Eliasson B,Cederholm J,Eeg-Olofsson K,Svensson AM,Zethelius B,Gudbjörnsdottir S,National Diabetes Register.

更新日期：2011-09-01 00:00:00

abstract：OBJECTIVE:To investigate the effect of normal aging on the protective responses against hypoglycemia, in view of the fact that type II diabetes is primarily a disease of aging, and its treatment is associated with risk of hypoglycemia with cognitive impairment. RESEARCH DESIGN AND METHODS:Plasma glucose was lowered st...

journal_title：Diabetes care

authors： Matyka K,Evans M,Lomas J,Cranston I,Macdonald I,Amiel SA

更新日期：1997-02-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to investigate whether genetic variants could influence the antidiabetic efficacy of gliclazide in type 2 diabetic patients. RESEARCH DESIGN AND METHODS:A total of 1,268 type 2 diabetic patients whose diabetes was diagnosed within the past 5 years and who had no recent hypoglyce...

journal_title：Diabetes care

authors： Feng Y,Mao G,Ren X,Xing H,Tang G,Li Q,Li X,Sun L,Yang J,Ma W,Wang X,Xu X

更新日期：2008-10-01 00:00:00

abstract：OBJECTIVE:To assess the efficacy of a lifestyle intervention program that can be readily translated into clinical practice for obese patients with type 2 diabetes. RESEARCH DESIGN AND METHODS:The study consisted of a 12-month randomized controlled trial of 147 health plan members with type 2 diabetes and obesity (BMI ...

journal_title：Diabetes care

authors： Wolf AM,Conaway MR,Crowther JQ,Hazen KY,L Nadler J,Oneida B,Bovbjerg VE,Improving Control with Activity and Nutrition (ICAN) Study.

更新日期：2004-07-01 00:00:00