Insulin withholding for weight control in women with diabetes.

Abstract:

OBJECTIVE:To provide a description of the clinical characteristics that distinguish individuals who withhold insulin for weight control from those who do not. Some individuals with insulin-dependent diabetes mellitus (IDDM) control their weight by withholding insulin and purging excessive calories. This process places patients at risk for developing severe hyperglycemia, diabetic ketoacidosis, and increases the risk of long-term complications of diabetes. RESEARCH DESIGN AND METHODS:Forty-two women with IDDM, ages 16-40, were interviewed and divided into two groups: insulin withholders (IWs) and non-insulin withholders (non-IWs). These groups were compared on physiological, behavioral, psychological, and psychiatric variables. RESULTS:Compared with non-IWs, patients who withheld insulin to control their weight exhibited poorer glycemic control, reported more negative attitudes toward diabetes, were more likely to have pathological scores on the Eating Disorder Inventory 2, and were more likely to report current or past symptoms of anorexia or bulimia nervosa. IWs were also more likely to report lying to physicians about their degree of compliance with their diabetes regimens. CONCLUSIONS:The results of this study indicated that IWs exhibit more symptoms associated with the spectrum of eating disorders than non-IWs. This study showed that insulin withholding for weight control not only exists, but is associated with some maladaptive symptoms and behaviors that need to be addressed by diabetes treatment teams.

journal_name

Diabetes Care

journal_title

Diabetes care

authors

Biggs MM,Basco MR,Patterson G,Raskin P

doi

10.2337/diacare.17.10.1186

subject

Has Abstract

pub_date

1994-10-01 00:00:00

pages

1186-9

issue

10

eissn

0149-5992

issn

1935-5548

journal_volume

17

pub_type

杂志文章
  • The midregional fragment of pro-A-type natriuretic peptide, blood pressure, and mortality in a prospective cohort study of patients with type 2 diabetes (ZODIAC-25).

    abstract:OBJECTIVE:Evidence that midregional fragment of pro-A-type natriuretic peptide (MR-proANP) is a marker of mortality in patients with type 2 diabetes is limited. Therefore, we aimed to investigate the capabilities of MR-proANP in predicting mortality. We also investigated whether MR-proANP influences the relationship be...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc12-0428

    authors: van Hateren KJ,Landman GW,Kleefstra N,Groenier KH,Struck J,Navis GJ,Bakker SJ,Houweling ST,van der Meer K,Bilo HJ

    更新日期:2013-05-01 00:00:00

  • Trends in health care expenditure in U.S. adults with diabetes: 2002-2011.

    abstract:OBJECTIVE:Direct medical cost of diabetes in the U.S. has been estimated to be 2.3 times higher relative to individuals without diabetes. This study examines trends in health care expenditures by expenditure category in U.S. adults with diabetes between 2002 and 2011. RESEARCH DESIGN AND METHODS:We analyzed 10 years o...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc15-0369

    authors: Ozieh MN,Bishu KG,Dismuke CE,Egede LE

    更新日期:2015-10-01 00:00:00

  • N-Glycan Profile and Kidney Disease in Type 1 Diabetes.

    abstract:OBJECTIVE:Poorer glycemic control in type 1 diabetes may alter N-glycosylation patterns on circulating glycoproteins, and these alterations may be linked with diabetic kidney disease (DKD). We investigated associations between N-glycans and glycemic control and renal function in type 1 diabetes. RESEARCH DESIGN AND ME...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc17-1042

    authors: Bermingham ML,Colombo M,McGurnaghan SJ,Blackbourn LAK,Vučković F,Pučić Baković M,Trbojević-Akmačić I,Lauc G,Agakov F,Agakova AS,Hayward C,Klarić L,Palmer CNA,Petrie JR,Chalmers J,Collier A,Green F,Lindsay RS,Macrury S

    更新日期:2018-01-01 00:00:00

  • Distortion-product otoacoustic emissions and selective sensorineural loss in IDDM.

    abstract:OBJECTIVE:To provide information about possible subclinical damage of the cochlear outer hair cells (OHCs) by means of transiently evoked otoacoustic emissions (TEOAEs) and distortion-product otoacoustic emissions (DPOAEs) in subjects with IDDM. RESEARCH DESIGN AND METHODS:TEOAEs and DPOAEs were recorded in 47 IDDM pa...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.21.8.1317

    authors: Di Nardo W,Ghirlanda G,Paludetti G,Cercone S,Saponara C,Del Ninno M,Di Girolamo S,Magnani P,Di Leo MA

    更新日期:1998-08-01 00:00:00

  • Guidelines for premeal insulin dose reduction for postprandial exercise of different intensities and durations in type 1 diabetic subjects treated intensively with a basal-bolus insulin regimen (ultralente-lispro).

    abstract:OBJECTIVE:To evaluate and validate appropriate premeal insulin dose reductions for postprandial exercises of different intensities and durations to minimize the risk of exercise-induced hypoglycemia in type 1 diabetic subjects. RESEARCH DESIGN AND METHODS:Eight male type 1 diabetic patients on a basal-bolus insulin re...

    journal_title:Diabetes care

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.2337/diacare.24.4.625

    authors: Rabasa-Lhoret R,Bourque J,Ducros F,Chiasson JL

    更新日期:2001-04-01 00:00:00

  • Impact of specific glucose-control strategies on microvascular and macrovascular outcomes in 58,000 adults with type 2 diabetes.

    abstract:OBJECTIVE:Comparative effectiveness research methods are used to compare the effect of four distinct glucose-control strategies on subsequent myocardial infarction and nephropathy in type 2 diabetes. RESEARCH DESIGN AND METHODS:A total of 58,000 adults with type 2 diabetes and A1C <7% (53 mmol/mol) while taking two or...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc12-2675

    authors: Neugebauer R,Fireman B,Roy JA,O'Connor PJ

    更新日期:2013-11-01 00:00:00

  • One-year results of a community-based translation of the Diabetes Prevention Program: Healthy-Living Partnerships to Prevent Diabetes (HELP PD) Project.

    abstract:OBJECTIVE:Although the Diabetes Prevention Program (DPP) and the Finnish Diabetes Prevention Study (FDPS) demonstrated that weight loss from lifestyle change reduces type 2 diabetes incidence in patients with prediabetes, the translation into community settings has been difficult. The objective of this study is to repo...

    journal_title:Diabetes care

    pub_type: 杂志文章,随机对照试验

    doi:10.2337/dc10-2115

    authors: Katula JA,Vitolins MZ,Rosenberger EL,Blackwell CS,Morgan TM,Lawlor MS,Goff DC Jr

    更新日期:2011-07-01 00:00:00

  • Trends in the prevalence of preexisting diabetes and gestational diabetes mellitus among a racially/ethnically diverse population of pregnant women, 1999-2005.

    abstract:OBJECTIVE:The purpose of this study was to assess changes in the prevalence of preexisting diabetes (diabetes antedating pregnancy) and gestational diabetes mellitus (GDM) from 1999 through 2005. RESEARCH DESIGN AND METHODS:In this retrospective study of 175,249 women aged 13-58 years with 209,287 singleton deliveries...

    journal_title:Diabetes care

    pub_type: 杂志文章,多中心研究

    doi:10.2337/dc07-2345

    authors: Lawrence JM,Contreras R,Chen W,Sacks DA

    更新日期:2008-05-01 00:00:00

  • Changes in A1C levels are significantly associated with changes in levels of the cardiovascular risk biomarker hs-CRP: results from the SteP study.

    abstract:OBJECTIVE:The effect of therapeutic strategies on cardiovascular (CV) disease can be evaluated by monitoring changes in CV risk biomarkers. This study investigated the effect of a structured self-monitoring of blood glucose (SMBG) protocol and the resulting improvements in glycemic control on changes in high-sensitivit...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc12-1711

    authors: Schnell O,Amann-Zalan I,Jelsovsky Z,Moritz A,Bermejo JL,Parkin CG,Schweitzer MA,Fisher L,Polonsky WH

    更新日期:2013-07-01 00:00:00

  • The validation of a diabetes patient knowledge test.

    abstract::Diabetes knowledge tests, used in conjunction with measures of patient attitudes and behaviors, can provide a useful basis for assessing educational needs and designing appropriate instructional experiences. Accurate decisions require instruments that measure patient knowledge of diabetes and its management with high ...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.6.6.591

    authors: Hess GE,Davis WK

    更新日期:1983-11-01 00:00:00

  • An Observational Study of the Equivalence of Age and Duration of Diabetes to Glycemic Control Relative to the Risk of Complications in the Combined Cohorts of the DCCT/EDIC Study.

    abstract:OBJECTIVE:This epidemiological analysis of the pooled Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) cohort describes the equivalence of a 1-percentage point increase in HbA1c (such as from 7% to 8%) and years of additional age or duration of type 1 diabete...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc20-0226

    authors: Bebu I,Braffett BH,Schade D,Sivitz W,Malone JI,Pop-Busui R,Lorenzi GM,Lee P,Trapani VR,Wallia A,Herman WH,Lachin JM,DCCT\/EDIC Research Group.

    更新日期:2020-10-01 00:00:00

  • A quantitative scale of acanthosis nigricans.

    abstract:OBJECTIVE:To develop and validate a scale for acanthosis nigricans (AN). RESEARCH DESIGN AND METHODS:Subjects were participants from the San Antonio Family Diabetes Study and the San Antonio Family Heart Study. A total of 406 subjects were independently examined for AN by at least two observers. Five locations were ex...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.22.10.1655

    authors: Burke JP,Hale DE,Hazuda HP,Stern MP

    更新日期:1999-10-01 00:00:00

  • Insulin-resistant diabetes with insulin receptor autoantibodies in a male patient without acanghosis nigricans.

    abstract::A 51-yr-old, nonobese, male patient presented with hyperglycemia and a recent 40-pound weight loss. Severe insulin resistance was documented in studies in which high amounts of insulin were infused using the Biostator GCIIS. Diabetic control was finally achieved with subcutaneous injections of 470 U of insulin per day...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.2.3.275

    authors: Baldwin D Jr,Winston E,Hoshizaki RJ,Garland JT,Baldwin D Sr,Holcomb HH,Flier JS,Rubenstein A

    更新日期:1979-05-01 00:00:00

  • Health-related quality of life and treatment satisfaction in Dutch patients with type 2 diabetes.

    abstract:OBJECTIVE:To estimate the health-related quality of life (HRQOL) and treatment satisfaction for patients with type 2 diabetes in the Netherlands and to examine which patient characteristics are associated with quality of life and treatment satisfaction. RESEARCH DESIGN AND METHODS:For a sample of 1,348 type 2 diabetes...

    journal_title:Diabetes care

    pub_type: 杂志文章,多中心研究

    doi:10.2337/diacare.25.3.458

    authors: Redekop WK,Koopmanschap MA,Stolk RP,Rutten GE,Wolffenbuttel BH,Niessen LW

    更新日期:2002-03-01 00:00:00

  • Exercise therapy in type 2 diabetes: is daily exercise required to optimize glycemic control?

    abstract:OBJECTIVE:Given the transient nature of exercise-induced improvements in insulin sensitivity, it has been speculated that daily exercise is preferred to maximize the benefits of exercise for glycemic control. The current study investigates the impact of daily exercise versus exercise performed every other day on glycem...

    journal_title:Diabetes care

    pub_type: 杂志文章,随机对照试验

    doi:10.2337/dc11-2112

    authors: van Dijk JW,Tummers K,Stehouwer CD,Hartgens F,van Loon LJ

    更新日期:2012-05-01 00:00:00

  • Alcohol consumption and the incidence of type 2 diabetes: a 20-year follow-up of the Finnish twin cohort study.

    abstract:OBJECTIVE:The aim of this study was to investigate alcohol consumption in relation to the incidence of type 2 diabetes. RESEARCH DESIGN AND METHODS:The study population consisted of 22778 twins of the Finnish Twin Cohort. This cohort was compiled in 1975 and includes all same-sexed twins born in Finland before 1958. I...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.26.10.2785

    authors: Carlsson S,Hammar N,Grill V,Kaprio J

    更新日期:2003-10-01 00:00:00

  • Accumulation of gene polymorphisms related to plaque disruption and thrombosis is associated with cerebral infarction in subjects with type 2 diabetes.

    abstract:OBJECTIVE:It is believed that disruption of vulnerable atherosclerotic plaque and subsequent thrombus formation play critical roles in the pathogenesis of cerebral infarction. We simultaneously determined four relatively common genetic variants related to plaque rupture or subsequent local thrombus formation and evalua...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc09-1518

    authors: Katakami N,Takahara M,Kaneto H,Shimizu I,Ohno K,Ishibashi F,Osonoi T,Kashiwagi A,Kawamori R,Shimomura I,Matsuhisa M,Yamasaki Y

    更新日期:2010-02-01 00:00:00

  • Urinary estriols: are they of value in normoglycemic diabetic pregnancy?

    abstract::The purpose of the study was to assess the value of 24-h urinary estriols in the management of diabetic pregnancies. Twenty-seven pregnant diabetic patients (White's class B through R) received insulin dosages twice daily as a combination of NPH and regular insulin. Laboratory and home monitored blood glucose was main...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.5.3.316

    authors: Fern PE,Grunert GM,Lewis SB

    更新日期:1982-05-01 00:00:00

  • High incidence of childhood-onset IDDM in Kuwait. Kuwait Study Group of Diabetes in Childhood.

    abstract:OBJECTIVE:To determine the incidence of insulin-dependent diabetes mellitus (IDDM) in children aged 0-14 years in Kuwait, as part of the World Health Organization Multinational Collaborative Study (DIAMOND), and to determine if the incidence rates have increased. RESEARCH DESIGN AND METHODS:All cases of IDDM diagnosed...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.18.7.923

    authors: Shaltout AA,Qabazard MA,Abdella NA,LaPorte RE,al Arouj M,Ben Nekhi A,Moussa MA,al Khawari MA

    更新日期:1995-07-01 00:00:00

  • The Prognostic Significance of Diabetes and Microvascular Complications in Patients With Heart Failure With Preserved Ejection Fraction.

    abstract:OBJECTIVE:This study examined the prognostic significance of diabetes and microvascular complications in patients with heart failure with preserved ejection fraction (HFpEF). RESEARCH DESIGN AND METHODS:This analysis included 3,385 patients (mean age 69 ± 9.6 years; 49% male; 89% white) with HFpEF from the Treatment o...

    journal_title:Diabetes care

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.2337/dc17-0755

    authors: Sandesara PB,O'Neal WT,Kelli HM,Samman-Tahhan A,Hammadah M,Quyyumi AA,Sperling LS

    更新日期:2018-01-01 00:00:00

  • Troponin T and pro-B-type natriuretic Peptide in fetuses of type 1 diabetic mothers.

    abstract:OBJECTIVE:Cardiomyopathy is noted in up to 40% of infants of diabetic mothers, and the exact mechanisms are unknown. The aim of this study was to determine whether fetal serum markers of cardiac function differ between normal and type 1 diabetic pregnancies and to examine the relationship between these markers and feta...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc09-0552

    authors: Russell NE,Higgins MF,Amaruso M,Foley M,McAuliffe FM

    更新日期:2009-11-01 00:00:00

  • Abnormal nerve conduction in impotent patients with diabetes mellitus.

    abstract::The etiology of impotence in the diabetic population has not been clearly defined. To assess this problem, 24 impotent diabetic subjects, 21 nonimpotent diabetic subjects, and 10 subjects with psychogenic impotence were compared with nocturnal monitoring of penile tumescence and rigidity, penile arterial blood flow, a...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.12.7.449

    authors: Daniels JS

    更新日期:1989-07-01 00:00:00

  • Lipid testing among patients with diabetes who receive diabetes care from primary care physicians.

    abstract:OBJECTIVE:To identify factors related to lipid testing among patients with diabetes who receive diabetes care from primary care physicians. RESEARCH DESIGN AND METHODS:North Carolina Medicare claims were used to identify individuals with diabetes who received diabetes care from primary care physicians. Lipid testing w...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.26.5.1369

    authors: Massing MW,Henley NS,Carter-Edwards L,Schenck AP,Simpson RJ Jr

    更新日期:2003-05-01 00:00:00

  • A health economic model to assess the long-term effects and cost-effectiveness of orlistat in obese type 2 diabetic patients.

    abstract:OBJECTIVES:Obesity is a common condition in type 2 diabetic patients. Treating obesity may enhance hypoglycemic treatment and contribute to the reduction of long-term microvascular and macrovascular complications. Orlistat reduces cardiovascular risk factors in obese type 2 diabetic patients. The objectives of this stu...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.25.2.303

    authors: Lamotte M,Annemans L,Lefever A,Nechelput M,Masure J

    更新日期:2002-02-01 00:00:00

  • Back to basics in diagnosing diabetic polyneuropathy with the tuning fork!

    abstract:OBJECTIVE:Several national and international scoring systems are used to diagnose diabetic polyneuropathy (PNP). The variety in these scores and the lack of data on validity and predictive value has led to a comparison and validation of the scores with clinical standards for PNP to determine the most powerful measureme...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.28.9.2201

    authors: Meijer JW,Smit AJ,Lefrandt JD,van der Hoeven JH,Hoogenberg K,Links TP

    更新日期:2005-09-01 00:00:00

  • Effect of moderate improvement in metabolic control on magnesium and lipid concentrations in patients with type 1 diabetes.

    abstract:OBJECTIVE:To evaluate the effect of clinically obtainable improvements in metabolic control in patients with type 1 diabetes on biochemical cardiovascular risk factors. RESEARCH DESIGN AND METHODS:Blood and 24-h urinary samples were obtained from 49 patients with type 1 diabetes before and after a run-in period and af...

    journal_title:Diabetes care

    pub_type: 临床试验,杂志文章

    doi:10.2337/diacare.22.4.546

    authors: Djurhuus MS,Henriksen JE,Klitgaard NA,Blaabjerg O,Thye-Rønn P,Altura BM,Altura BT,Beck-Nielsen H

    更新日期:1999-04-01 00:00:00

  • Insulin gene mutations as cause of diabetes in children negative for five type 1 diabetes autoantibodies.

    abstract:OBJECTIVE:Heterozygous, gain-of-function mutations of the insulin gene can cause permanent diabetes with onset ranging from the neonatal period through adulthood. The aim of our study was to screen for the insulin gene in patients who had been clinically classified as type 1 diabetic but who tested negative for type 1 ...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc08-0783

    authors: Bonfanti R,Colombo C,Nocerino V,Massa O,Lampasona V,Iafusco D,Viscardi M,Chiumello G,Meschi F,Barbetti F

    更新日期:2009-01-01 00:00:00

  • Efficacy of metabolic and psychological screening for mood disorders among children with type 1 diabetes.

    abstract:OBJECTIVE:To compare the diagnostic accuracy and time expenditure of screening models based on glycated hemoglobin (HbA(1c)) level and psychometric measures for mood disorder (MD) among children with type 1 diabetes. RESEARCH DESIGN AND METHODS:With semistructured clinical interviews (Schedule for Affective Disorders ...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc12-0160

    authors: Butwicka A,Fendler W,Zalepa A,Szadkowska A,Mianowska B,Gmitrowicz A,Młynarski W

    更新日期:2012-11-01 00:00:00

  • Motor vehicle accidents and IDDM.

    abstract::A case-control study examining the 1-yr motor vehicle accident experiences of 158 insulin-dependent diabetes mellitus (IDDM) cases and 158 nondiabetic siblings was undertaken to evaluate the risk of motor vehicle accidents among drivers with IDDM. In multivariate analyses the overall accident risk of the cases and con...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.11.9.701

    authors: Songer TJ,LaPorte RE,Dorman JS,Orchard TJ,Cruickshanks KJ,Becker DJ,Drash AL

    更新日期:1988-10-01 00:00:00

  • Randomized effectiveness trial of a computer-assisted intervention to improve diabetes care.

    abstract:OBJECTIVE:There is a well-documented gap between diabetes care guidelines and the services received by patients in most health care settings. This report presents 12-month follow-up results from a computer-assisted, patient-centered intervention to improve the level of recommended services patients received from a vari...

    journal_title:Diabetes care

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.2337/diacare.28.1.33

    authors: Glasgow RE,Nutting PA,King DK,Nelson CC,Cutter G,Gaglio B,Rahm AK,Whitesides H

    更新日期:2005-01-01 00:00:00