Trends in health care expenditure in U.S. adults with diabetes: 2002-2011.

abstract：OBJECTIVE:To assess the efficacy and safety of initial combination therapy with sitagliptin and metformin in patients with type 2 diabetes and inadequate glycemic control on diet and exercise. RESEARCH DESIGN AND METHODS:In a 24-week, randomized, double-blind, placebo-controlled, parallel-group study, 1,091 patients w...

journal_title：Diabetes care

authors： Goldstein BJ,Feinglos MN,Lunceford JK,Johnson J,Williams-Herman DE,Sitagliptin 036 Study Group.

更新日期：2007-08-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to determine whether a strategy of aggressive cardiovascular risk management reduced the mortality associated with diabetic foot ulceration. RESEARCH DESIGN AND METHODS:After an initial audit of outcomes demonstrating a high mortality rate in 404 diabetic foot ulcer patients wit...

journal_title：Diabetes care

authors： Young MJ,McCardle JE,Randall LE,Barclay JI

更新日期：2008-11-01 00:00:00

abstract：OBJECTIVE:To estimate the within-person variability (SDi) for the overnight urinary albumin excretion rate (AER) in diabetic patients with persistent microalbuminuria. RESEARCH DESIGN AND METHODS:Thirteen normotensive diabetic patients in stable medical control, with normal renal function and without any associated ca...

journal_title：Diabetes care

authors： Phillipou G,Phillips PJ

更新日期：1994-05-01 00:00:00

abstract：OBJECTIVE:To examine whether the association between gestational diabetes mellitus (GDM) and BMI category varies by racial/ethnic group. RESEARCH DESIGN AND METHODS:In a cohort of 123,040 women without recognized pregravid diabetes who delivered babies between 1995 and 2006 at Kaiser Permanente of Northern California,...

journal_title：Diabetes care

authors： Hedderson M,Ehrlich S,Sridhar S,Darbinian J,Moore S,Ferrara A

更新日期：2012-07-01 00:00:00

abstract：OBJECTIVE:To investigate the influence of the insertion/deletion polymorphism of the ACE gene on the progression of early diabetic glomerulopathy in patients with and without antihypertensive treatment (AHT). RESEARCH DESIGN AND METHODS:There were 30 microalbuminuric patients with >5 years of type 1 diabetes who had r...

journal_title：Diabetes care

authors： Rudberg S,Rasmussen LM,Bangstad HJ,Osterby R

更新日期：2000-04-01 00:00:00

abstract：:The readability of written instructional materials for diabetic patients is an important consideration in their use. We assessed the readability of six commonly used patient teaching guides on diabetic self-care. In addition, two pamphlets developed by our program for diabetic patients with fifth to tenth grade readin...

journal_title：Diabetes care

authors： Leichter SB,Nieman JA,Moore RW,Collins P,Rhodes A

更新日期：1981-11-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to determine whether the use of meal bolus alarms would result in fewer missed meal boluses per week in youth with type 1 diabetes using continuous subcutaneous insulin infusion (CSII) therapy. RESEARCH DESIGN AND METHODS:This was a randomized trial of 48 youth using CSII, who were ...

journal_title：Diabetes care

authors： Chase HP,Horner B,McFann K,Yetzer H,Gaston J,Banion C,Fiallo-Scharer R,Slover R,Klingensmith G

更新日期：2006-05-01 00:00:00

abstract：OBJECTIVE:To assess the impact of bariatric surgery (BS) on incident microvascular complications of diabetes-related foot disease (DFD), sight-threatening diabetic retinopathy (STDR), and chronic kidney disease (CKD) in patients with type 2 diabetes and obesity. RESEARCH DESIGN AND METHODS:A retrospective matched, con...

journal_title：Diabetes care

authors： Singh P,Adderley N,Subramanian A,Gokhale K,Singhal R,Toulis KA,Bellary S,Nirantharakumar K,Tahrani AA

更新日期：2021-01-01 00:00:00

abstract：:A higher prevalence of stroke is found in the patient with both diagnosed and undiagnosed diabetes and glucose intolerance. Because of local cerebral acidosis caused by ischemia and hyperglycemia, morbidity and mortality from a stroke are increased. Most studies show that individuals with admission serum glucose > 120...

journal_title：Diabetes care

authors： Bell DS

更新日期：1994-03-01 00:00:00

abstract：OBJECTIVE:Glycemic control using inhaled, dry-powder insulin plus a single injection of long-acting insulin was compared with a conventional regimen in patients with type 2 diabetes, which was previously managed with at least two daily insulin injections. RESEARCH DESIGN AND METHODS:Patients were randomized to 6 month...

journal_title：Diabetes care

authors： Hollander PA,Blonde L,Rowe R,Mehta AE,Milburn JL,Hershon KS,Chiasson JL,Levin SR

更新日期：2004-10-01 00:00:00

abstract：:In seven type II (non-insulin-dependent) diabetic patients, given either 50 g glucose or a mixed meal potentially containing 61 g glucose as starch and sucrose, the postmeal plasma glucose area integrated over 4 h was less after the mixed meal. The insulin area was considerably greater (2.1-fold). The greater increase...

journal_title：Diabetes care

authors： Nuttall FQ,Gannon MC

更新日期：1988-01-01 00:00:00

abstract：:An implantable glucose sensor is being developed that is based on the use of a high-area platinum electrode. The sensor is operated in a controlled potential mode, in which the potential of the platinum working electrode versus an unpolarized reference electrode is periodically varied according to a preselected voltag...

journal_title：Diabetes care

authors： Lerner H,Soeldner JS,Colton CK,Giner J

更新日期：1982-05-01 00:00:00

abstract：OBJECTIVE:Acute hypoglycemia impairs cognitive function in several domains. Executive cognitive function governs organization of thoughts, prioritization of tasks, and time management. This study examined the effect of acute hypoglycemia on executive function in adults with and without diabetes. RESEARCH DESIGN AND ME...

journal_title：Diabetes care

authors： Graveling AJ,Deary IJ,Frier BM

更新日期：2013-10-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to compare an in vivo test of whole-body glycolysis, the deuterated-glucose disposal test (2H-GDT), with insulin sensitivity measured by the euglycemic-hyperinsulinemic glucose clamp and the steady-state plasma glucose (SSPG) test. RESEARCH DESIGN AND METHODS:The 2H-GDT consists...

journal_title：Diabetes care

authors： Beysen C,Murphy EJ,McLaughlin T,Riiff T,Lamendola C,Turner HC,Awada M,Turner SM,Reaven G,Hellerstein MK

更新日期：2007-05-01 00:00:00

abstract：OBJECTIVE:To determine whether ACE inhibitors (ACEi) and angiotensin receptor blockers (ARB) protect against lower-respiratory tract infections complicating type 2 diabetes. RESEARCH DESIGN AND METHODS:Of 1,732 participants with diabetes recruited to the longitudinal observational Fremantle Diabetes Study Phase II (FD...

journal_title：Diabetes care

authors： Davis TME,Davis WA

更新日期：2020-09-01 00:00:00

abstract：OBJECTIVE:To assess the success and baseline predictors of maintaining glycemic control for up to 5 years of therapy using basal insulin glargine or standard glycemic care in people with dysglycemia treated with zero or one oral glucose-lowering agents. RESEARCH DESIGN AND METHODS:Data from 12,537 participants in the ...

journal_title：Diabetes care

authors： ORIGIN Trial Investigators.

更新日期：2013-10-01 00:00:00

abstract：OBJECTIVE:To describe the extent to which hyperglycemia, hypertension, and dyslipidemia are currently detected, treated, and controlled in U.S. veterans with diabetes with and without ischemic heart disease (IHD). RESEARCH DESIGN AND METHODS:A cohort of 3,769 veterans who self-reported diabetes and who received all he...

journal_title：Diabetes care

authors： Smith NL,Chen L,Au DH,McDonell M,Fihn SD

更新日期：2004-05-01 00:00:00

abstract：OBJECTIVE:We aimed to determine the effect of elevated BMI over time on the progression to type 1 diabetes in youth. RESEARCH DESIGN AND METHODS:We studied 1,117 children in the TrialNet Pathway to Prevention cohort (autoantibody-positive relatives of patients with type 1 diabetes). Longitudinally accumulated BMI abov...

journal_title：Diabetes care

authors： Ferrara CT,Geyer SM,Liu YF,Evans-Molina C,Libman IM,Besser R,Becker DJ,Rodriguez H,Moran A,Gitelman SE,Redondo MJ,Type 1 Diabetes TrialNet Study Group.

更新日期：2017-05-01 00:00:00

abstract：OBJECTIVE:There is growing evidence linking time in range (TIR), an emerging metric for assessing glycemic control, to diabetes-related outcomes. We aimed to investigate the association between TIR and mortality in patients with type 2 diabetes. RESEARCH DESIGN AND METHODS:A total of 6,225 adult patients with type 2 d...

journal_title：Diabetes care

authors： Lu J,Wang C,Shen Y,Chen L,Zhang L,Cai J,Lu W,Zhu W,Hu G,Xia T,Zhou J

更新日期：2021-02-01 00:00:00

abstract：OBJECTIVE:To compare the effect of morning and bedtime NPH insulin combined with daytime sulfonylurea on glycemic control in non-insulin-dependent diabetes mellitus (NIDDM) patients no longer responding to treatment with sulfonylureas alone. RESEARCH DESIGN AND METHODS:Twenty-four NIDDM patients who fulfilled these cr...

journal_title：Diabetes care

authors： Groop LC,Widén E,Ekstrand A,Saloranta C,Franssila-Kallunki A,Schalin-Jäntti C,Eriksson JG

更新日期：1992-07-01 00:00:00

abstract：OBJECTIVE:Previous studies demonstrate that the metabolic syndrome is associated with distal symmetric polyneuropathy (DSP). We aimed to determine the magnitude of this effect and the precise components involved. RESEARCH DESIGN AND METHODS:We determined the symptomatic DSP prevalence in the Health, Aging, and Body Co...

journal_title：Diabetes care

authors： Callaghan BC,Xia R,Banerjee M,de Rekeneire N,Harris TB,Newman AB,Satterfield S,Schwartz AV,Vinik AI,Feldman EL,Strotmeyer ES,Health ABC Study.

更新日期：2016-05-01 00:00:00

abstract：OBJECTIVE:To examine counterregulatory responses during spontaneous nocturnal hypoglycemia in prepubertal children with type 1 diabetes. RESEARCH DESIGN AND METHODS:A total of 29 prepubertal patients with type 1 diabetes underwent two overnight profiles. Data were analyzed from 16 children (median [range] 8.7 [5.9-12....

journal_title：Diabetes care

authors： Matyka KA,Crowne EC,Havel PJ,Macdonald IA,Matthews D,Dunger DB

更新日期：1999-07-01 00:00:00

abstract：OBJECTIVE:To provide an overview of the Department of Veterans Affairs (VA) research activities, highlighting diabetes-related research. RESEARCH DESIGN AND METHODS:Diabetes is an important component of the VA research portfolio. All four VA research services support aspects of diabetes research. VA diabetes research ...

journal_title：Diabetes care

authors： Reiber GE,Boyko EJ

更新日期：2004-05-01 00:00:00

abstract：:OBJECTIVE Using the clamp technique, youths with a clinical diagnosis of type 2 diabetes (CDx-type 2 diabetes) and positive pancreatic autoantibodies (Ab(+)) were shown to have severe impairment in insulin secretion and less insulin resistance than their peers with negative antibodies (Ab(-)). In this study, we invest...

journal_title：Diabetes care

authors： Tfayli H,Bacha F,Gungor N,Arslanian S

更新日期：2010-03-01 00:00:00

abstract：OBJECTIVE:Little is known about medial arterial calcification (MAC) other than its association with age, sex, diabetes, and diabetes complications. Familial aggregation of this disorder was studied to determine the importance of potential genetic factors and to assess whether such familial aggregation was independent o...

journal_title：Diabetes care

authors： Narayan KM,Pettitt DJ,Hanson RL,Bennett PH,Fernandes RJ,De Courten M,Rose FA,Knowler WC

更新日期：1996-09-01 00:00:00

abstract：OBJECTIVE:Diabetes has been associated with chronic neurodegeneration. We performed a systematic review and meta-analysis to assess the relationship between pre-existing diabetes and Parkinson's disease (PD). RESEARCH DESIGN AND METHODS:Original articles in English published up to 10 May 2011 were searched for in elec...

journal_title：Diabetes care

authors： Cereda E,Barichella M,Pedrolli C,Klersy C,Cassani E,Caccialanza R,Pezzoli G

更新日期：2011-12-01 00:00:00

abstract：OBJECTIVE:The sympathetic nervous system and thiazolidinediones control lipid metabolism and have been implicated in body weight regulation. This study was conducted to determine whether the simultaneous activation of these two signaling systems might synergize to exert beneficial effects on the expression of key genes...

journal_title：Diabetes care

authors： Bogacka I,Gettys TW,de Jonge L,Nguyen T,Smith JM,Xie H,Greenway F,Smith SR

更新日期：2007-05-01 00:00:00

abstract：OBJECTIVE:To describe the clinical experience and the pharmacokinetics of U-500 regular insulin in severely insulin-resistant obese type 2 diabetic patients. RESEARCH DESIGN AND METHODS:Patients requiring >200 units of insulin with A1C levels >8.0% were switched to U-500 regular insulin. For the pharmacokinetic study,...

journal_title：Diabetes care

authors： Davidson MB,Navar MD,Echeverry D,Duran P

更新日期：2010-02-01 00:00:00

abstract：:OBJECTIVE Mortality rates have declined substantially over the past decades in the general population, but the situation among diabetic subjects is less clear. The aim of this study was to analyze mortality trends in diabetic and nondiabetic subjects during 1972-2004. RESEARCH DESIGN AND METHODS Since 1972, all patien...

journal_title：Diabetes care

authors： Jansson SP,Andersson DK,Svärdsudd K

更新日期：2010-03-01 00:00:00

abstract：OBJECTIVE:Oxidative stress has been shown to be increased in the postprandial period in patients with diabetes and has been implicated in the pathogenesis of micro- and macrovascular complications. The aim of this post hoc analysis was to assess the effects of pramlintide, an amylin analog shown to reduce postprandial ...

journal_title：Diabetes care

authors： Ceriello A,Piconi L,Quagliaro L,Wang Y,Schnabel CA,Ruggles JA,Gloster MA,Maggs DG,Weyer C

更新日期：2005-03-01 00:00:00