Time in Range in Relation to All-Cause and Cardiovascular Mortality in Patients With Type 2 Diabetes: A Prospective Cohort Study.

abstract：OBJECTIVE:To examine the significance of individual risk factors on the development of diabetes in subjects who underwent screening for diabetes. RESEARCH DESIGN AND METHODS:A total of 1,649 Chinese subjects underwent screening for diabetes. They were asymptomatic but had known risk factors for diabetes, including a p...

journal_title：Diabetes care

authors： Ko GT,Chan JC,Tsang LW,Yeung VT,Chow CC,Cockram CS

更新日期：2000-09-01 00:00:00

abstract：OBJECTIVE:The mechanisms by which diabetes leads to rapidly progressive atherosclerosis are not fully understood. Adherence of monocytes to the arterial wall is an early event in the development of atherosclerotic lesions. RESEARCH DESIGN AND METHODS:The binding of freshly isolated monocytes from patients with NIDDM, ...

journal_title：Diabetes care

authors： Hoogerbrugge N,Verkerk A,Jacobs ML,Postema PT,Jongkind JF

更新日期：1996-10-01 00:00:00

abstract：OBJECTIVE:To investigate whether the presence of antibody markers at diagnosis could help predict the rapid decrease in residual beta-cell function noted in some, but not all, patients with recent-onset type 1 diabetes. RESEARCH DESIGN AND METHODS:We measured random C-peptide levels (radioimmunoassay); islet cell cyto...

journal_title：Diabetes care

authors： Decochez K,Keymeulen B,Somers G,Dorchy H,De Leeuw IH,Mathieu C,Rottiers R,Winnock F,ver Elst K,Weets I,Kaufman L,Pipeleers DG,Gorus FK,Belgian Diabetes Registry.

更新日期：2000-08-01 00:00:00

abstract：OBJECTIVE:To evaluate whether, in adolescents with type 1 diabetes, the addition of metformin to insulin and standard diabetes management results in 1) higher insulin sensitivity and 2) lower HbA1c, fasting glucose, insulin dosage (units per kilogram per day) and BMI. RESEARCH DESIGN AND METHODS:This was a randomized,...

journal_title：Diabetes care

authors： Hamilton J,Cummings E,Zdravkovic V,Finegood D,Daneman D

更新日期：2003-01-01 00:00:00

abstract：OBJECTIVE:Diabetic nephropathy (DN) is a leading cause of end-stage renal disease (ESRD). Obstructive sleep apnea (OSA) is common in type 2 diabetes and increases oxidative stress. Hence, OSA could promote the development and progression of DN. RESEARCH DESIGN AND METHODS:This was a cohort study in adults with type 2 ...

journal_title：Diabetes care

authors： Tahrani AA,Ali A,Raymond NT,Begum S,Dubb K,Altaf QA,Piya MK,Barnett AH,Stevens MJ

更新日期：2013-11-01 00:00:00

abstract：OBJECTIVE:To determine the prevalence of IGT and diabetes and identify the occurrence of CVD and its risk factors. RESEARCH DESIGN AND METHODS:This study was a population-based, cross-sectional study of 110,660 residents, 25-74 yr of age of DaQing, Hei Long Jiang Province, China. RESULTS:Using 1985 WHO criteria, 577 ...

journal_title：Diabetes care

authors： Pan XR,Hu YH,Li GW,Liu PA,Bennett PH,Howard BV

更新日期：1993-01-01 00:00:00

abstract：OBJECTIVE:To describe market trends for antidiabetic drugs, focusing on newly approved drugs, concomitant use of antidiabetic drugs, and effects of safety concerns and access restrictions on thiazolidinedione use. RESEARCH DESIGN AND METHODS:Nationally projected data on antidiabetic prescriptions for adults dispensed ...

journal_title：Diabetes care

authors： Hampp C,Borders-Hemphill V,Moeny DG,Wysowski DK

更新日期：2014-01-01 00:00:00

abstract：:The availability of insulin analogs has offered insulin replacement strategies that are proposed to more closely mimic normal human physiology. Specifically, there are a considerable number of reports demonstrating that prandial insulin analogs (lispro, aspart, glulisine) have pharmacokinetic and pharmacodynamic profi...

journal_title：Diabetes care

authors： Davidson MB

更新日期：2014-06-01 00:00:00

abstract：:Metformin is and has been considered as first-line therapy for type 2 diabetes for over a quarter of a century. Like other biguanides, metformin can cause a lactic acidosis that is exceptionally rare but fatal. The likelihood of metformin-associated lactic acidosis is substantially higher in patients with kidney impai...

journal_title：Diabetes care

authors： Bakris GL,Molitch ME

更新日期：2016-07-01 00:00:00

abstract：OBJECTIVE:This study was conducted to investigate the association of diabetic peripheral neuropathy (DPN) with both arterial stiffness and intima-media thickness (IMT). RESEARCH DESIGN AND METHODS:We conducted a cross-sectional analysis of 731 subjects with type 2 diabetes. DPN was diagnosed on the basis of neuropathi...

journal_title：Diabetes care

authors： Kim ES,Moon SD,Kim HS,Lim DJ,Cho JH,Kwon HS,Ahn CW,Yoon KH,Kang MI,Cha BY,Son HY

更新日期：2011-06-01 00:00:00

abstract：OBJECTIVE:A large proportion of vulvovaginal candidiasis (VVC) in diabetes is due to non-albicans Candida species such as C. glabrata and C. tropicalis. Observational studies indicate that diabetic patients with C. glabrata VVC respond poorly to azole drugs. We evaluated the response to oral fluconazole and boric acid ...

journal_title：Diabetes care

authors： Ray D,Goswami R,Banerjee U,Dadhwal V,Goswami D,Mandal P,Sreenivas V,Kochupillai N

更新日期：2007-02-01 00:00:00

abstract：OBJECTIVE:Emerging epidemiological evidence suggests that higher magnesium intake may reduce diabetes incidence. We aimed to examine the association between magnesium intake and risk of type 2 diabetes by conducting a meta-analysis of prospective cohort studies. RESEARCH DESIGN AND METHODS:We conducted a PubMed databa...

journal_title：Diabetes care

authors： Dong JY,Xun P,He K,Qin LQ

更新日期：2011-09-01 00:00:00

abstract：OBJECTIVE:To determine the value of measuring serum triglyceride (TG) levels early in pregnancy for predicting late-gestation glucose tolerance and neonatal birth weight ratio (BWR) (birth weight corrected for gestational age). RESEARCH DESIGN AND METHODS:The relationships between morning nonfasting TG measured early ...

journal_title：Diabetes care

authors： Nolan CJ,Riley SF,Sheedy MT,Walstab JE,Beischer NA

更新日期：1995-12-01 00:00:00

abstract：OBJECTIVE:Type 1 diabetes mellitus causes increased carotid intima-media thickness (IMT) in adults. We evaluated IMT in young subjects with type 1 diabetes. RESEARCH DESIGN AND METHODS:Participants with type 1 diabetes (N = 402) were matched to controls (N = 206) by age, sex, and race or ethnicity. Anthropometric and ...

journal_title：Diabetes care

authors： Urbina EM,Dabelea D,D'Agostino RB Jr,Shah AS,Dolan LM,Hamman RF,Daniels SR,Marcovina S,Wadwa RP

更新日期：2013-09-01 00:00:00

abstract：OBJECTIVE:To determine the safety and efficacy of the long-acting insulin analog, insulin glargine, as a component of basal bolus therapy in patients with type 1 diabetes. RESEARCH DESIGN AND METHODS:Patients with type 1 diabetes receiving basal-bolus insulin treatment with NPH human insulin and insulin lispro were ra...

journal_title：Diabetes care

authors： Raskin P,Klaff L,Bergenstal R,Hallé JP,Donley D,Mecca T

更新日期：2000-11-01 00:00:00

abstract：OBJECTIVE:To study determinants of incident hyperglycemia in rural Indian mothers 6 years after delivery. RESEARCH DESIGN AND METHODS:The Pune Maternal Nutrition Study collected information in six villages near Pune on prepregnant characteristics and nutrition, physical activity, and glucose tolerance during pregnancy...

journal_title：Diabetes care

authors： Kulkarni SR,Fall CH,Joshi NV,Lubree HG,Deshpande VU,Pasarkar RV,Bhat DS,Naik SS,Yajnik CS

更新日期：2007-10-01 00:00:00

abstract：OBJECTIVE:The objectives of this study were to compare early predictive marker of the metabolic syndrome with proopiomelanocortin (POMC) methylation status and to determine the association among birth weight, ponderal index, and cord blood methylation status. RESEARCH DESIGN AND METHODS:We collected pregnancy outcome ...

journal_title：Diabetes care

authors： Yoo JY,Lee S,Lee HA,Park H,Park YJ,Ha EH,Kim YJ

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:There is suggestive evidence linking hypoglycemia with cardiovascular disease, but few data have been collected in a community-based setting. Information is lacking on individual cardiovascular outcomes and cause-specific mortality. RESEARCH DESIGN AND METHODS:We conducted a prospective cohort analysis of 1,...

journal_title：Diabetes care

authors： Lee AK,Warren B,Lee CJ,McEvoy JW,Matsushita K,Huang ES,Sharrett AR,Coresh J,Selvin E

更新日期：2018-01-01 00:00:00

abstract：OBJECTIVE:To evaluate whether plasma levels of free fatty acids (FFAs) are independently associated with incidence of type 2 diabetes. RESEARCH DESIGN AND METHODS:A case-cohort design was used to randomly select 580 incident cases of diabetes and 566 noncases from 10,275 African-American and white men and women in the...

journal_title：Diabetes care

authors： Pankow JS,Duncan BB,Schmidt MI,Ballantyne CM,Couper DJ,Hoogeveen RC,Golden SH,Atherosclerosis Risk in Communities Study.

更新日期：2004-01-01 00:00:00

abstract：:OBJECTIVE We evaluated relationships of oral glucose tolerance testing (OGTT)-derived measures of insulin sensitivity and pancreatic β-cell function with indices of diabetes complications in a cross-sectional study of patients with type 2 diabetes who are free of overt cardiovascular or renal disease. RESEARCH DESIGN ...

journal_title：Diabetes care

authors： Mulvey CK,McNeill AM,Girman CJ,Churchill TW,Terembula K,Ferguson JF,Shah R,Mehta NN,Qasim AN,Rickels MR,Reilly MP

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:To compare the efficacy and safety of once-weekly semaglutide 1.0 mg s.c. with exenatide extended release (ER) 2.0 mg s.c. in subjects with type 2 diabetes. RESEARCH DESIGN AND METHODS:In this phase 3a, open-label, parallel-group, randomized controlled trial, 813 subjects with type 2 diabetes taking oral ant...

journal_title：Diabetes care

authors： Ahmann AJ,Capehorn M,Charpentier G,Dotta F,Henkel E,Lingvay I,Holst AG,Annett MP,Aroda VR

更新日期：2018-02-01 00:00:00

abstract：OBJECTIVE:To investigate whether the risk for autoimmune diabetes in adults differs between socioeconomic groups and to compare such risk with that for type 2 diabetes. RESEARCH DESIGN AND METHODS:The inhabitants of the Norwegian county of Nord-Trøndelag were investigated by questionnaires and clinical examinations on...

journal_title：Diabetes care

authors： Olsson L,Ahlbom A,Grill V,Midthjell K,Carlsson S

更新日期：2011-01-01 00:00:00

abstract：OBJECTIVE:To assess the long-term cost-effectiveness of aspirin use among adults aged >or=40 years with newly diagnosed type 2 diabetes. RESEARCH DESIGN AND METHODS:We used a validated cost-effectiveness model of type 2 diabetes to assess the lifetime health and cost consequences of use or nonuse of aspirin. The model...

journal_title：Diabetes care

authors： Li R,Zhang P,Barker LE,Hoerger TJ

更新日期：2010-06-01 00:00:00

abstract：OBJECTIVE:To examine the contribution of nerve-axon reflex-related vasodilation to total acetylcholine-induced vasodilation in the skin of normal and diabetic subjects. RESEARCH DESIGN AND METHODS:The skin microcirculation was evaluated at the forearm level in 69 healthy subjects and 42 nonneuropathic diabetic patient...

journal_title：Diabetes care

authors： Hamdy O,Abou-Elenin K,LoGerfo FW,Horton ES,Veves A

更新日期：2001-02-01 00:00:00

abstract：OBJECTIVE:Dietary protein is an important modulator of glucose metabolism. However, studies regarding the association between dietary protein intake and gestational diabetes mellitus (GDM) risk are sparse. This study was to examine the association. RESEARCH DESIGN AND METHODS:Our study included 21,457 singleton pregna...

journal_title：Diabetes care

authors： Bao W,Bowers K,Tobias DK,Hu FB,Zhang C

更新日期：2013-07-01 00:00:00

abstract：OBJECTIVE:To compare the glycemic profiles of patients with type 1 diabetes treated with either an implantable insulin pump or pancreas or islet transplantation by the means of the continuous glucose monitoring system (CGMS; Minimed, Sylmar, CA). RESEARCH DESIGN AND METHODS:The CGMS enabled recording of subcutaneous g...

journal_title：Diabetes care

authors： Kessler L,Passemard R,Oberholzer J,Benhamou PY,Bucher P,Toso C,Meyer P,Penfornis A,Badet L,Wolf P,Colin C,Morel P,Pinget M,GRAGIL Group.

更新日期：2002-12-01 00:00:00

abstract：OBJECTIVE:Glycemic control using inhaled, dry-powder insulin plus a single injection of long-acting insulin was compared with a conventional regimen in patients with type 2 diabetes, which was previously managed with at least two daily insulin injections. RESEARCH DESIGN AND METHODS:Patients were randomized to 6 month...

journal_title：Diabetes care

authors： Hollander PA,Blonde L,Rowe R,Mehta AE,Milburn JL,Hershon KS,Chiasson JL,Levin SR

更新日期：2004-10-01 00:00:00

abstract：OBJECTIVE:The objective of this study was to determine whether high levels of HDL cholesterol are associated with a lower prevalence of albuminuria RESEARCH DESIGN AND METHODS:We analyzed the lipid profiles of patients with type 1 diabetes of > or = 20 years duration in 42 patients with albuminuria (28 microalbuminuri...

journal_title：Diabetes care

authors： Molitch ME,Rupp D,Carnethon M

更新日期：2006-01-01 00:00:00

abstract：OBJECTIVE:Many patients with early diabetes remain untreated. Our objectives were to identify clinical predictors of 1) worsening glycemic control and 2) medical treatment initiation in response to worsening glycemic control among patients with type 2 diabetes. RESEARCH DESIGN AND METHODS:We identified 5,804 type 2 di...

journal_title：Diabetes care

authors： Pani LN,Nathan DM,Grant RW

更新日期：2008-03-01 00:00:00

abstract：OBJECTIVE:This study examined the long-term consequences for offspring born to mothers with pregestational type 1 diabetes regarding mortality, hospital admissions, and medication. We also examined the association between HbA1c levels during pregnancy and mortality and incidence of hospital admissions. RESEARCH DESIGN...

journal_title：Diabetes care

authors： Knorr S,Stochholm K,Vlachová Z,Bytoft B,Clausen TD,Jensen RB,Juul S,Ovesen P,Damm P,Beck-Nielsen H,Jensen DM,Gravholt CH

更新日期：2015-05-01 00:00:00