Variability of urinary albumin excretion in patients with microalbuminuria.

abstract：OBJECTIVE:A combined analysis of whether islet cell autoantibodies (ICAs) are cross-reactive with mouse pancreas, with glutamate decarboxylase (GAD) antibodies, and with 64K antibodies was performed in a large sample of recently diagnosed type I diabetic patients. The disappearance rates of these different autoantibodi...

journal_title：Diabetes care

authors： Chaillous L,Delamaire M,Martignat L,Maugendre D,Marre M,Mathieu E,Limal JM,Charbonnel B,Allannic H,Saï P

更新日期：1994-10-01 00:00:00

abstract：:The risk of severe hypoglycemia associated with the particular therapeutic approach of two University hospitals was assessed in 96% of all patients with insulin-dependent diabetes mellitus (IDDM) who had been admitted during a period of almost 3 yr to the diabetic wards of two hospitals and who participated in a struc...

journal_title：Diabetes care

authors： Mühlhauser I,Berger M,Sonnenberg G,Koch J,Jörgens V,Schernthaner G,Scholz V,Pädagogin D

更新日期：1985-05-01 00:00:00

abstract：OBJECTIVE:Several national and international scoring systems are used to diagnose diabetic polyneuropathy (PNP). The variety in these scores and the lack of data on validity and predictive value has led to a comparison and validation of the scores with clinical standards for PNP to determine the most powerful measureme...

journal_title：Diabetes care

authors： Meijer JW,Smit AJ,Lefrandt JD,van der Hoeven JH,Hoogenberg K,Links TP

更新日期：2005-09-01 00:00:00

abstract：OBJECTIVE:The effect of therapeutic strategies on cardiovascular (CV) disease can be evaluated by monitoring changes in CV risk biomarkers. This study investigated the effect of a structured self-monitoring of blood glucose (SMBG) protocol and the resulting improvements in glycemic control on changes in high-sensitivit...

journal_title：Diabetes care

authors： Schnell O,Amann-Zalan I,Jelsovsky Z,Moritz A,Bermejo JL,Parkin CG,Schweitzer MA,Fisher L,Polonsky WH

更新日期：2013-07-01 00:00:00

abstract：OBJECTIVE:This study analyzed the lifetime health care expenditures and life years lost associated with diabetes in the U.S. RESEARCH DESIGN AND METHODS:Data from the National Health Interview Survey (NHIS), the Medical Expenditure Panel Survey from 1997 to 2000, and the NHIS Linked Mortality Public-use Files with a m...

journal_title：Diabetes care

authors： Leung MY,Pollack LM,Colditz GA,Chang SH

更新日期：2015-03-01 00:00:00

abstract：:Glycosylated serum protein (GSP) and glycosylated hemoglobin (GHb) were measured in 263 insulin-dependent and 41 non-insulin-dependent diabetic subjects. Both indices provided useful information in type II diabetes, but were extremely poor in judging control in type I diabetes. In both groups, there was poor correlati...

journal_title：Diabetes care

authors： Mehl TD,Wenzel SE,Russell B,Gardner D,Merimee TJ

更新日期：1983-01-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to assess changes in the prevalence of preexisting diabetes (diabetes antedating pregnancy) and gestational diabetes mellitus (GDM) from 1999 through 2005. RESEARCH DESIGN AND METHODS:In this retrospective study of 175,249 women aged 13-58 years with 209,287 singleton deliveries...

journal_title：Diabetes care

authors： Lawrence JM,Contreras R,Chen W,Sacks DA

更新日期：2008-05-01 00:00:00

abstract：OBJECTIVE:To determine the pharmacokinetic (PK) and glucodynamic (GD) dose response of human insulin inhalation powder (HIIP) delivered via AIR particle technology and dose equivalence to subcutaneous (SC) insulin lispro. RESEARCH DESIGN AND METHODS:Twenty healthy, nonsmoking, male or female subjects (aged 29.6 +/- 6....

journal_title：Diabetes care

authors： Rave KM,Nosek L,de la Peña A,Seger M,Ernest CS 2nd,Heinemann L,Batycky RP,Muchmore DB

更新日期：2005-10-01 00:00:00

abstract：OBJECTIVE:Continuous glucose monitoring (CGM) reduces HbA1c and time spent in hypoglycemia in people with type 1 diabetes (T1D) treated with multiple daily insulin injections (MDI) when evaluated over shorter time periods. It is unclear to what extent CGM improves and helps to maintain glucose control, treatment satisf...

journal_title：Diabetes care

authors： Lind M,Ólafsdóttir AF,Hirsch IB,Bolinder J,Dahlqvist S,Pivodic A,Hellman J,Wijkman M,Schwarcz E,Albrektsson H,Heise T,Polonsky W

更新日期：2021-01-01 00:00:00

abstract：:Regulation of gene transcription is a major action of insulin. Most of the greater than 20 examples of this effect involve the stimulation of transcription, but a few involve an inhibition. The inhibition of transcription of the phosphoenolpyruvate carboxykinase (PEPCK) gene has been studied in detail. Most of this ef...

journal_title：Diabetes care

authors： O'Brien RM,Granner DK

更新日期：1990-03-01 00:00:00

abstract：OBJECTIVE:Longitudinal changes in GAD antibody (Ab) and ICA512/IA-2 (ICA512) Ab were examined in relation to age at the onset of diabetes and autoimmunity against the thyroid gland. RESEARCH DESIGN AND METHODS:GADAb, ICA512Ab, and antithyroid autoantibody were examined at onset in 40 juvenile-onset IDDM patients (17 m...

journal_title：Diabetes care

authors： Yokota I,Matsuda J,Naito E,Ito M,Shima K,Kuroda Y

更新日期：1998-01-01 00:00:00

abstract：OBJECTIVE:Type 1 diabetes has been associated with factors related to welfare and social class. During the past decade, Lithuania has experienced a transition period, leading to dramatic changes in the socioeconomic structure of the society. RESEARCH DESIGN AND METHODS:Incidence in the group aged 0-39 years by urban-r...

journal_title：Diabetes care

authors： Pundziute-Lyckå A,Urbonaite B,Ostrauskas R,Zalinkevicius R,Dahlquist GG

更新日期：2003-03-01 00:00:00

abstract：OBJECTIVE:To investigate the possibility that leptin levels may be predictive of the risk of ischemic heart disease (IHD) through the relationship of leptin to body fat. RESEARCH DESIGN AND METHODS:The Quebec Cardiovascular Study cohort consisted of 2,103 French-Canadian men without IHD in 1985 who were followed until...

journal_title：Diabetes care

authors： Couillard C,Lamarche B,Mauriège P,Cantin B,Dagenais GR,Moorjani S,Lupien PJ,Després JP

更新日期：1998-05-01 00:00:00

abstract：OBJECTIVE:To summarize the efficacy of metformin in reducing BMI and cardiometabolic risk in obese children and adolescents without diabetes. RESEARCH DESIGN AND METHODS:We performed a systematic review and meta-analysis of randomized controlled trials (RCTs). Double-blind RCTs of > or =6 months duration in obese subj...

journal_title：Diabetes care

authors： Park MH,Kinra S,Ward KJ,White B,Viner RM

更新日期：2009-09-01 00:00:00

abstract：OBJECTIVE:Preclinical data suggest that linagliptin, a dipeptidyl peptidase-4 inhibitor, may lower urinary albumin excretion. The ability of linagliptin to lower albuminuria on top of renin-angiotensin-aldosterone system (RAAS) inhibition in humans was analyzed by pooling data from four similarly designed, 24-week, ran...

journal_title：Diabetes care

authors： Groop PH,Cooper ME,Perkovic V,Emser A,Woerle HJ,von Eynatten M

更新日期：2013-11-01 00:00:00

abstract：OBJECTIVE:Cost-effectiveness analyses have reported that intensive glucose control is not cost-effective in older patients with new-onset diabetes. However, these analyses have had limited data on patient preferences concerning diabetic health states. We examined how the cost- effectiveness of intensive glucose control...

journal_title：Diabetes care

authors： Huang ES,Shook M,Jin L,Chin MH,Meltzer DO

更新日期：2006-02-01 00:00:00

abstract：:Chemical test strips for estimating blood glucose have been shown to be reliable, rapid, and convenient when properly used. This study compares a new product, the Ames Visidex (Miles Laboratories, Elkhart, Indiana), and an established product, the Bio-Dynamics Chemstrip bG (Boehringer-Mannheim, Indianapolis, Indiana) ...

journal_title：Diabetes care

authors： Frindik JP,Kassner DA,Pirkle DA,Kemp SF,Hoff C

更新日期：1983-11-01 00:00:00

abstract：:Twenty-eight patients with type I diabetes mellitus, legally blind as a result of proliferative retinopathy, were recruited into a program designed to teach and evaluate tactile methods for self-monitoring of blood glucose (SMBG). Vision ranged from "blind" to "able to read large print." Techniques with wipe-off strip...

journal_title：Diabetes care

authors： Prior JC,Alojado NC,Hunt JA,Begg IS

更新日期：1984-07-01 00:00:00

abstract：:OBJECTIVE--To assess kidney function and AER in patients with PD. RESEARCH DESIGN AND METHODS--Thirty-three patients with PD (age 52 +/- 7 yr, duration of disease 11 +/- 6 yr, BMI 24 +/- 3 kg/m2) and 33 patients with IDDM were matched for sex, BMI, and duration of disease. GFR and RPF were determined by single injecti...

journal_title：Diabetes care

authors： Tiengo A,Briani G,Scaldaferri E,Riva F,Jori E,Sgnaolin E,Fenato R,D'Ambrosio M,Fioretto P,Nosadini R

更新日期：1992-11-01 00:00:00

abstract：OBJECTIVE:Early puberty is associated with increased risk of subsequent cardiovascular disease. Low sex hormone-binding globulin (SHBG) levels are a feature of early puberty and of conditions associated with increased cardiovascular risk. The aim of the present study was to evaluate SHBG as a predictor of glucose metab...

journal_title：Diabetes care

authors： Sørensen K,Aksglaede L,Munch-Andersen T,Aachmann-Andersen NJ,Petersen JH,Hilsted L,Helge JW,Juul A

更新日期：2009-05-01 00:00:00

abstract：OBJECTIVE:To compare the effects of repaglinide, glipizide, and glibenclamide on insulin secretion and postprandial glucose after a single standard 500-kcal test meal. RESEARCH DESIGN AND METHODS:A total of 12 type 2 diabetic patients with early diabetes (mean HbA(1c) of 6.1%) and 12 matched control subjects were enro...

journal_title：Diabetes care

authors： Cozma LS,Luzio SD,Dunseath GJ,Langendorg KW,Pieber T,Owens DR

更新日期：2002-08-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to compare the University of Texas (UT) and Site, Ischemia, Neuropathy, Bacterial Infection, and Depth (SINBAD) foot ulcer scores in predicting ulcer outcome within a routine diabetes foot clinic. RESEARCH DESIGN AND METHODS:From 2006 to 2018, data were collected from all patients a...

journal_title：Diabetes care

authors： Leese GP,Soto-Pedre E,Schofield C

更新日期：2021-02-01 00:00:00

abstract：OBJECTIVE:To assess the association of 1-h plasma glucose (1hPG) and inflammation with normal glucose tolerance (NGT) and pre-diabetes. RESEARCH DESIGN AND METHODS:A cohort of 1,062 subjects was enrolled. After oral glucose load (oral glucose tolerance test), we compared subjects with NGT and pre-diabetes above and be...

journal_title：Diabetes care

authors： Bardini G,Dicembrini I,Cresci B,Rotella CM

更新日期：2010-02-01 00:00:00

abstract：:The American Diabetes Association (ADA) "Standards of Medical Care in Diabetes" includes the ADA's current clinical practice recommendations and is intended to provide the components of diabetes care, general treatment goals and guidelines, and tools to evaluate quality of care. Members of the ADA Professional Practic...

journal_title：Diabetes care

authors： American Diabetes Association.

更新日期：2021-01-01 00:00:00

abstract：OBJECTIVE:In children with type 1 diabetes (T1D), severe hypoglycemia (SH) is associated with poorer cognition, but the association of SH with cognitive function in late life is unknown. Given the increasing life expectancy in people with T1D, understanding the role of SH in brain health is crucial. RESEARCH DESIGN AN...

journal_title：Diabetes care

authors： Lacy ME,Gilsanz P,Eng C,Beeri MS,Karter AJ,Whitmer RA

更新日期：2020-03-01 00:00:00

abstract：OBJECTIVE:We have demonstrated high heritability of insulin secretion measured as acute insulin response to glucose times insulin sensitivity (disposition index). Furthermore, we showed that obese normoglycemic family members of a type 2 diabetic proband failed to compensate for the insulin resistance of obesity by inc...

journal_title：Diabetes care

authors： Elbein SC,Sun J,Scroggin E,Teng K,Hasstedt SJ

更新日期：2001-03-01 00:00:00

abstract：OBJECTIVE:To evaluate statin use in the U.S. before and after the 2015 American Diabetes Association position statement, which expanded statin therapy recommendations to include all adults 40-75 years old with diabetes. RESEARCH DESIGN AND METHODS:The National Health and Nutrition Examination Survey (NHANES) was used ...

journal_title：Diabetes care

authors： Leino AD,Dorsch MP,Lester CA

更新日期：2020-12-01 00:00:00

abstract：OBJECTIVE:Wound healing is known to require a well-organized balance of numerous factors, e.g., cytokines, matrix metalloproteinases (MMPs), and their inhibitors, as well as direct cell-cell communication (connexins). Disruption of this balance may lead to the formation of chronic wounds such as diabetic foot ulcers. T...

journal_title：Diabetes care

authors： Brandner JM,Zacheja S,Houdek P,Moll I,Lobmann R

更新日期：2008-01-01 00:00:00

abstract：OBJECTIVE:To determine the fatty acid composition of serum phospholipid, triglyceride, and cholesterol ester fractions and to analyze the lipid profile of microalbuminuric type 2 diabetic patients. RESEARCH DESIGN AND METHODS:A case-control study was conducted with 72 patients: 37 were normoalbuminuric (urinary albumi...

journal_title：Diabetes care

authors： Perassolo MS,Almeida JC,Prá RL,Mello VD,Maia AL,Moulin CC,Camargo JL,Zelmanovitz T,Azevedo MJ,Gross JL

更新日期：2003-03-01 00:00:00

abstract：OBJECTIVE:Hyperglycemia is a common condition in hospitalized patients. The aim of this study was to investigate the relationships between glycemia upon admission and mortality in a heterogeneous group of adult patients. RESEARCH DESIGN AND METHODS:The 3-year records released from a general hospital were associated wi...

journal_title：Diabetes care

authors： Bruno A,Gregori D,Caropreso A,Lazzarato F,Petrinco M,Pagano E

更新日期：2008-11-01 00:00:00