Back to basics in diagnosing diabetic polyneuropathy with the tuning fork!

abstract：OBJECTIVE:Obesity is associated with alterations in corticolimbic-striatal brain regions involved in food motivation and reward. Stress and the presence of food cues may each motivate eating and engage corticolimibic-striatal neurocircuitry. It is unknown how these factors interact to influence brain responses and whet...

journal_title：Diabetes care

authors： Jastreboff AM,Sinha R,Lacadie C,Small DM,Sherwin RS,Potenza MN

更新日期：2013-02-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to evaluate the effects of a combination weight loss program using intermittent low-calorie diets, energy-controlled meal replacement products, and sibutramine on weight loss, diabetes control, and cardiovascular risk factors in overweight or obese subjects with type 2 diabetes. ...

journal_title：Diabetes care

authors： Redmon JB,Raatz SK,Reck KP,Swanson JE,Kwong CA,Fan Q,Thomas W,Bantle JP

更新日期：2003-09-01 00:00:00

abstract：OBJECTIVE:To compare a simple meal plan emphasizing healthy food choices with a traditional exchange-based meal plan in reducing HbA(1c) levels in urban African Americans with type 2 diabetes. RESEARCH DESIGN AND METHODS:A total of 648 patients with type 2 diabetes were randomized to receive instruction in either a he...

journal_title：Diabetes care

authors： Ziemer DC,Berkowitz KJ,Panayioto RM,El-Kebbi IM,Musey VC,Anderson LA,Wanko NS,Fowke ML,Brazier CW,Dunbar VG,Slocum W,Bacha GM,Gallina DL,Cook CB,Phillips LS

更新日期：2003-06-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to investigate the presence and correlates of clinically relevant cognitive impairment in middle-aged adults with childhood-onset type 1 diabetes (T1D). RESEARCH DESIGN AND METHODS:During 2010-2013, 97 adults diagnosed with T1D and aged <18 years (age and duration 49 ± 7 and 41 ± 6 ...

journal_title：Diabetes care

authors： Nunley KA,Rosano C,Ryan CM,Jennings JR,Aizenstein HJ,Zgibor JC,Costacou T,Boudreau RM,Miller R,Orchard TJ,Saxton JA

更新日期：2015-09-01 00:00:00

abstract：OBJECTIVE:To evaluate whether there is a difference in the association between nonalcoholic fatty liver disease (NAFLD) and incident diabetes based on the presence of impaired fasting glucose. RESEARCH DESIGN AND METHODS:A total of 7,849 individuals (5,409 men and 2,440 women) without diabetes, who underwent comprehen...

journal_title：Diabetes care

authors： Bae JC,Rhee EJ,Lee WY,Park SE,Park CY,Oh KW,Park SW,Kim SW

更新日期：2011-03-01 00:00:00

abstract：OBJECTIVE:To examine ankle-brachial index (ABI) abnormalities in patients with type 2 diabetes and coronary artery disease (CAD). RESEARCH DESIGN AND METHODS:An ABI was obtained in 2,240 patients in the Bypass Angioplasty Revascularization Investigation 2 Diabetes (BARI 2D) Trial. ABIs were classified as: normal, 0.91...

journal_title：Diabetes care

authors： Singh PP,Abbott JD,Lombardero MS,Sutton-Tyrrell K,Woodhead G,Venkitachalam L,Tsapatsaris NP,Piemonte TC,Lago RM,Rutter MK,Nesto RW,Bypass Angioplasty Revascularization Investigation 2 Diabetes Study Group.

更新日期：2011-02-01 00:00:00

abstract：OBJECTIVE:To clarify the contribution of the Asp905Tyr polymorphism of the muscle-specific glycogen-targeting subunit of protein phosphatase 1 (PP1G) to insulin resistance and related diseases. RESEARCH DESIGN AND METHODS:We investigated the Asp905Tyr polymorphism of the PPP1R3 gene, which encodes the muscle-specific ...

journal_title：Diabetes care

authors： Shen GQ,Ikegami H,Kawaguchi Y,Fujisawa T,Hamada Y,Ueda H,Shintani M,Nojima K,Kawabata Y,Yamada K,Babaya N,Ogihara T

更新日期：1998-07-01 00:00:00

abstract：OBJECTIVE:To compare the efficacy and safety of two doses of once-weekly dulaglutide, a glucagon-like peptide 1 receptor agonist, to sitagliptin in uncontrolled, metformin-treated patients with type 2 diabetes. The primary objective was to compare (for noninferiority and then superiority) dulaglutide 1.5 mg versus sita...

journal_title：Diabetes care

authors： Nauck M,Weinstock RS,Umpierrez GE,Guerci B,Skrivanek Z,Milicevic Z

更新日期：2014-08-01 00:00:00

abstract：OBJECTIVE:Uncertainty remains regarding the predictive value of various glycemic measures as they relate to the risk of diabetes and its complications. Using the cutoffs recommended by the American Diabetes Association's 2010 criteria, we determined the associations of fasting plasma glucose (FPG), 2-h postload glucose...

journal_title：Diabetes care

authors： Lu J,He J,Li M,Tang X,Hu R,Shi L,Su Q,Peng K,Xu M,Xu Y,Chen Y,Yu X,Yan L,Wang T,Zhao Z,Qin G,Wan Q,Chen G,Dai M,Zhang D,Gao Z,Wang G,Shen F,Luo Z,Qin Y,Chen L,Huo Y,Li Q,Ye Z,Zhang Y,Du R,Che

更新日期：2019-08-01 00:00:00

abstract：OBJECTIVE:To examine the safety and efficacy of dapagliflozin, a sodium-glucose cotransporter-2 inhibitor, added on to pioglitazone in type 2 diabetes inadequately controlled on pioglitazone. RESEARCH DESIGN AND METHODS:Treatment-naive patients or those receiving metformin, sulfonylurea, or thiazolidinedione entered a...

journal_title：Diabetes care

authors： Rosenstock J,Vico M,Wei L,Salsali A,List JF

更新日期：2012-07-01 00:00:00

abstract：OBJECTIVE:To investigate whether dietary phylloquinone and menaquinones intakes are related to risk of type 2 diabetes. RESEARCH DESIGN AND METHODS:We used data from a prospective cohort study in 38,094 Dutch men and women, aged 20-70 years. Dietary phylloquinone and menaquinones intakes were assessed using a validate...

journal_title：Diabetes care

authors： Beulens JW,van der A DL,Grobbee DE,Sluijs I,Spijkerman AM,van der Schouw YT

更新日期：2010-08-01 00:00:00

abstract：OBJECTIVE:Intensive lifestyle intervention significantly reduced diabetes incidence among the participants in the Finnish Diabetes Prevention Study. We investigated whether and to what extent risk factors for type 2 diabetes and other baseline characteristics of the study participants modified the effectiveness of the ...

journal_title：Diabetes care

authors： Lindström J,Peltonen M,Eriksson JG,Aunola S,Hämäläinen H,Ilanne-Parikka P,Keinänen-Kiukaanniemi S,Uusitupa M,Tuomilehto J,Finnish Diabetes Prevention Study (DPS) Group.

更新日期：2008-05-01 00:00:00

abstract：OBJECTIVE:There is a well-documented gap between diabetes care guidelines and the services received by patients in most health care settings. This report presents 12-month follow-up results from a computer-assisted, patient-centered intervention to improve the level of recommended services patients received from a vari...

journal_title：Diabetes care

authors： Glasgow RE,Nutting PA,King DK,Nelson CC,Cutter G,Gaglio B,Rahm AK,Whitesides H

更新日期：2005-01-01 00:00:00

abstract：OBJECTIVE:High triglyceride (TG) levels and low HDL cholesterol (HDL-C) levels are risk factors for cardiovascular disease. It is unclear whether this relationship depends on glycemic dysregulation, sex, or LDL cholesterol (LDL-C) level. RESEARCH DESIGN AND METHODS:We studied 3,216 participants (40% men, 41% with diab...

journal_title：Diabetes care

authors： Lee JS,Chang PY,Zhang Y,Kizer JR,Best LG,Howard BV

更新日期：2017-04-01 00:00:00

abstract：OBJECTIVE:In 2010, the American Heart Association defined seven metrics (smoking, BMI, physical activity, diet, total cholesterol, blood pressure, and fasting plasma glucose) for ideal cardiovascular health (ICH). Subsequent studies have shown that the prevalence of achieving these metrics is very low in the general po...

journal_title：Diabetes care

authors： Alman AC,Maahs DM,Rewers MJ,Snell-Bergeon JK

更新日期：2014-02-01 00:00:00

abstract：OBJECTIVE:To test the utility of homeostasis model assessment (HOMA) in predicting insulin sensitivity [x10(- 4) min(-1)/(microIU/ml)] in children and to develop and compare two new prediction equations for insulin sensitivity in children using demographic and anthropometric measures in the presence or absence of fasti...

journal_title：Diabetes care

authors： Huang TT,Johnson MS,Goran MI

更新日期：2002-07-01 00:00:00

abstract：OBJECTIVE:Stress hyperglycemia increases the risk of mortality and poor outcomes in patients with acute myocardial infarction (AMI). We aimed to assess effects of intravenous nicorandil administered before reperfusion on AMI patients with stress hyperglycemia. RESEARCH DESIGN AND METHODS:This study consisted of 158 co...

journal_title：Diabetes care

authors： Ishii H,Ichimiya S,Kanashiro M,Amano T,Matsubara T,Murohara T

更新日期：2006-02-01 00:00:00

abstract：OBJECTIVE:This study aimed to assess the direct cost incurred by diabetic subjects who were in different income groups in urban and rural India, as well as to examine the changing trends of costs in the urban setting from 1998 to 2005. RESEARCH DESIGN AND METHODS:A total of 556 diabetic subjects from various urban and...

journal_title：Diabetes care

authors： Ramachandran A,Ramachandran S,Snehalatha C,Augustine C,Murugesan N,Viswanathan V,Kapur A,Williams R

更新日期：2007-02-01 00:00:00

abstract：OBJECTIVE:To determine the pharmacokinetic (PK) and glucodynamic (GD) dose response of human insulin inhalation powder (HIIP) delivered via AIR particle technology and dose equivalence to subcutaneous (SC) insulin lispro. RESEARCH DESIGN AND METHODS:Twenty healthy, nonsmoking, male or female subjects (aged 29.6 +/- 6....

journal_title：Diabetes care

authors： Rave KM,Nosek L,de la Peña A,Seger M,Ernest CS 2nd,Heinemann L,Batycky RP,Muchmore DB

更新日期：2005-10-01 00:00:00

abstract：OBJECTIVE:To determine contributions of trunk and extremity adiposity to cardiometabolic risk factors (blood pressure, fasting blood glucose, HDL cholesterol, and triglycerides) among white and African American adults. RESEARCH DESIGN AND METHODS:The sample consisted of 1,129 white women, 779 African American women, 1...

journal_title：Diabetes care

authors： Hu G,Bouchard C,Bray GA,Greenway FL,Johnson WD,Newton RL Jr,Ravussin E,Ryan DH,Katzmarzyk PT

更新日期：2011-06-01 00:00:00

abstract：OBJECTIVE:Ipragliflozin, a sodium-glucose cotransporter 2 inhibitor, stimulates glycosuria and lowers glycemia in patients with type 2 diabetes (T2DM). The objective of this study was to assess the pharmacodynamics of ipragliflozin in T2DM patients with impaired renal function. RESEARCH DESIGN AND METHODS:Glycosuria w...

journal_title：Diabetes care

authors： Ferrannini E,Veltkamp SA,Smulders RA,Kadokura T

更新日期：2013-05-01 00:00:00

abstract：OBJECTIVE:To provide an overview of the Department of Veterans Affairs (VA) research activities, highlighting diabetes-related research. RESEARCH DESIGN AND METHODS:Diabetes is an important component of the VA research portfolio. All four VA research services support aspects of diabetes research. VA diabetes research ...

journal_title：Diabetes care

authors： Reiber GE,Boyko EJ

更新日期：2004-05-01 00:00:00

abstract：OBJECTIVE:Patients with diabetes have a higher case fatality rate in myocardial infarction (MI) or stroke than those without diabetes: that is, MI and stroke are more often fatal if diabetes is present. We investigated whether the risk of MI or stroke being fatal in type 2 diabetes can be estimated using information av...

journal_title：Diabetes care

authors： Stevens RJ,Coleman RL,Adler AI,Stratton IM,Matthews DR,Holman RR

更新日期：2004-01-01 00:00:00

abstract：OBJECTIVE:Whether ACE inhibition is useful for type 2 diabetic patients with micro- and macroalbuminuria remains unknown. The Non-Insulin-Dependent Diabetes, Hypertension, Microalbuminuria, Cardiovascular Events and Ramipril (DIABHYCAR) Study was set up to address this issue through a multicenter double-blind parallel ...

journal_title：Diabetes care

authors： Marre M,Lièvre M,Vasmant D,Gallois Y,Hadjadj S,Reglier JC,Chatellier G,Mann J,Viberti GC,Passa P

更新日期：2000-04-01 00:00:00

abstract：OBJECTIVE:To determine insulin-dependent diabetes mellitus (IDDM) incidence rates for the first time in Seoul, Korea, from 1985 to 1988. RESEARCH DESIGN AND METHODS:A mail survey was conducted among all hospitals, a total of 136, with > 80 beds in the Seoul area. Of these, (15.4%) hospitals reported patients with newl...

journal_title：Diabetes care

authors： Ko KW,Yang SW,Cho NH

更新日期：1994-12-01 00:00:00

abstract：OBJECTIVE:We evaluated the prevalence of endothelial dysfunction as measured by flow-mediated dilatation (FMD) of the brachial artery and carotid intima-media thickness (c-IMT) in relationship to vascular inflammatory biomarkers in preadolescent children with type 1 diabetes. RESEARCH DESIGN AND METHODS:We studied 21 ...

journal_title：Diabetes care

authors： Babar GS,Zidan H,Widlansky ME,Das E,Hoffmann RG,Daoud M,Alemzadeh R

更新日期：2011-03-01 00:00:00

abstract：OBJECTIVE:Physical activity is a cornerstone of treatment for diabetes, yet people with diabetes perform less moderate and vigorous physical activity (MVPA) than people without diabetes. In contrast, whether differences in walking activity exist has been understudied. Diabetes-specific barriers to physical activity are...

journal_title：Diabetes care

authors： Huebschmann AG,Crane LA,Belansky ES,Scarbro S,Marshall JA,Regensteiner JG

更新日期：2011-08-01 00:00:00

abstract：OBJECTIVE:To examine patients' views of the acceptability of and satisfaction with telephone care center support provided to improve blood glucose control in type 2 diabetes. RESEARCH DESIGN AND METHODS:The Pro-Active Call-Center Treatment Support (PACCTS) Trial randomized patients from 47 general practices in a depri...

journal_title：Diabetes care

authors： Long AF,Gambling T,Young RJ,Taylor J,Mason JM,PACCTS Team.

更新日期：2005-02-01 00:00:00

abstract：:This review focuses on recent advances in molecular biology as they pertain to the insulin gene and diabetes mellitus. The structure of the human insulin gene is examined, and factors related to its normal functioning in the beta cells of the pancreas are explored. DNA polymorphisms near the insulin locus and their re...

journal_title：Diabetes care

authors： Permutt MA,Chirgwin J,Rotwein P,Giddings S

更新日期：1984-07-01 00:00:00

abstract：OBJECTIVE:To examine the prevalence and incidence of unrecognized myocardial infarction in a contemporary population with type 2 diabetes. RESEARCH DESIGN AND METHODS:We performed a retrospective analysis of the electrocardiograms (ECGs) recorded at baseline and after 2 years for the first 1,004 type 2 diabetic indivi...

journal_title：Diabetes care

authors： MacDonald MR,Petrie MC,Home PD,Komajda M,Jones NP,Beck-Nielsen H,Gomis R,Hanefeld M,Pocock SJ,Curtis PS,McMurray JJ

更新日期：2011-06-01 00:00:00