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Incidence and prevalence of unrecognized myocardial infarction in people with diabetes: a substudy of the Rosiglitazone Evaluated for Cardiac Outcomes and Regulation of Glycemia in Diabetes (RECORD) study.

Abstract：

OBJECTIVE:To examine the prevalence and incidence of unrecognized myocardial infarction in a contemporary population with type 2 diabetes. RESEARCH DESIGN AND METHODS:We performed a retrospective analysis of the electrocardiograms (ECGs) recorded at baseline and after 2 years for the first 1,004 type 2 diabetic individuals to be randomized in the Rosiglitazone Evaluated for Cardiac Outcomes and Regulation of Glycemia in Diabetes (RECORD) study. RESULTS:ECGs suitable for analysis were obtained from 669 participants. The prevalence of unrecognized Q-wave myocardial infarction at baseline was 1.9% (n = 13). The incidence of unrecognized Q-wave myocardial infarction at the end of 2 years of follow-up was 1.5/1,000-person-years (n = 2). One-third (13 of 39) of prevalent and one-quarter (2 of 8) of incident myocardial infarctions were unrecognized. CONCLUSIONS:Although the prevalence and incidence of myocardial infarction was low, unrecognized Q-wave myocardial infarctions made up a substantial proportion of all events.

journal_name

Diabetes Care

journal_title

Diabetes care

authors

MacDonald MR,Petrie MC,Home PD,Komajda M,Jones NP,Beck-Nielsen H,Gomis R,Hanefeld M,Pocock SJ,Curtis PS,McMurray JJ

doi

10.2337/dc10-2398

subject

Has Abstract

pub_date

2011-06-01 00:00:00

pages

1394-6

issue

6

eissn

0149-5992

issn

1935-5548

pii

dc10-2398

journal_volume

34

pub_type

杂志文章,多中心研究,随机对照试验

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