Multisystemic therapy for adolescents with poorly controlled type 1 diabetes: reduced diabetic ketoacidosis admissions and related costs over 24 months.

abstract：OBJECTIVE:The goal was to assess the 1-year efficacy and safety of the addition of pioglitazone or metformin to existing sulfonylurea (SU) therapy in patients with inadequately controlled type 2 diabetes. RESEARCH DESIGN AND METHODS:In this multicenter, double-blind study, patients were randomized to receive either pi...

journal_title：Diabetes care

authors： Hanefeld M,Brunetti P,Schernthaner GH,Matthews DR,Charbonnel BH,QUARTET Study Group.

更新日期：2004-01-01 00:00:00

abstract：OBJECTIVE:Poorer glycemic control in type 1 diabetes may alter N-glycosylation patterns on circulating glycoproteins, and these alterations may be linked with diabetic kidney disease (DKD). We investigated associations between N-glycans and glycemic control and renal function in type 1 diabetes. RESEARCH DESIGN AND ME...

journal_title：Diabetes care

authors： Bermingham ML,Colombo M,McGurnaghan SJ,Blackbourn LAK,Vučković F,Pučić Baković M,Trbojević-Akmačić I,Lauc G,Agakov F,Agakova AS,Hayward C,Klarić L,Palmer CNA,Petrie JR,Chalmers J,Collier A,Green F,Lindsay RS,Macrury S

更新日期：2018-01-01 00:00:00

abstract：OBJECTIVE:To examine the relationships between plasma 25-hydroxyvitamin D [25(OH)D] and in vivo insulin sensitivity and β-cell function relative to insulin sensitivity, disposition index (DI), in black and white youth. RESEARCH DESIGN AND METHODS:Plasma 25(OH)D concentrations were analyzed in banked specimens in healt...

journal_title：Diabetes care

authors： Rajakumar K,de las Heras J,Lee S,Holick MF,Arslanian SA

更新日期：2012-03-01 00:00:00

abstract：OBJECTIVE:To evaluate the utility of GAD antibodies (GADAs) and islet antigen-2 antibodies (IA-2As) in prediction of type 1 diabetes over 27 years in the general population and to assess the 6-year rates of seroconversion. RESEARCH DESIGN AND METHODS:A total of 3,475 nondiabetic subjects aged 3-18 years were sampled i...

journal_title：Diabetes care

authors： Knip M,Korhonen S,Kulmala P,Veijola R,Reunanen A,Raitakari OT,Viikari J,Akerblom HK

更新日期：2010-06-01 00:00:00

abstract：OBJECTIVE:Bariatric surgery may induce remission of type 2 diabetes in obese patients. However, estimates of remission rates reported in the literature range from 25 to 81%, contributing to the uncertainty patients and physicians both face as they assess treatment options. This analysis attempts to reconcile the seemin...

journal_title：Diabetes care

authors： Isaman DJ,Rothberg AE,Herman WH

更新日期：2016-12-01 00:00:00

abstract：OBJECTIVE:To verify what information from oral glucose tolerance tests (OGTTs) independently predicts mortality. RESEARCH DESIGN AND METHODS:A total of 1,401 initially nondiabetic participants from the Baltimore Longitudinal Study of Aging aged 17-95 years underwent one or more OGTTs (median 2, range 1-8), with insuli...

journal_title：Diabetes care

authors： Metter EJ,Windham BG,Maggio M,Simonsick EM,Ling SM,Egan JM,Ferrucci L

更新日期：2008-05-01 00:00:00

abstract：OBJECTIVE:To determine the proportion of patients with gestational diabetes mellitus (GDM) who have serological characteristics typical of IDDM. RESEARCH DESIGN AND METHODS:Islet cell antibodies (ICAs), insulin autoantibodies (IAAs), GAD65, and IA-2 antibodies were measured in 145 pregnant women with GDM, 33 with impa...

journal_title：Diabetes care

authors： Dozio N,Beretta A,Belloni C,Castiglioni M,Rosa S,Bosi E,Bonifacio E

更新日期：1997-01-01 00:00:00

abstract：OBJECTIVE:To evaluate the effect of the erythromycin derivative EM523L on gastric emptying and postprandial insulin requirement in insulin-dependent diabetic patients with severe gastroparesis. RESEARCH DESIGN AND METHODS:In six IDDM patients with severe gastroparesis (two men and four women, mean age 44.5 years [rang...

journal_title：Diabetes care

authors： Ishii M,Nakamura T,Kasai F,Baba T,Takebe K

更新日期：1997-07-01 00:00:00

abstract：OBJECTIVE:To determine the prevalence of type 2 diabetes and impaired fasting glycemia (IFG) in a tribal population of Bangladesh. RESEARCH DESIGN AND METHODS:A cluster sampling of 1,287 tribal subjects of age > or =20 years was investigated. They live in a hilly area of Khagrachari in the far northeast of Bangladesh....

journal_title：Diabetes care

authors： Abu Sayeed M,Mahtab H,Akter Khanam P,Abul Ahsan K,Banu A,Rashid AN,Azad Khan AK

更新日期：2004-05-01 00:00:00

abstract：OBJECTIVE:To compare the weight losses of black and white patients with NIDDM treated in a year-long behavioral weight loss program. RESEARCH DESIGN AND METHODS:Subjects were randomly assigned to a behavioral program that either used a low-calorie diet throughout or included two 12-week periods of a very-low calorie d...

journal_title：Diabetes care

authors： Wing RR,Anglin K

更新日期：1996-05-01 00:00:00

abstract：:OBJECTIVE To determine if glucose and C-peptide values obtained as part of the Hyperglycemia and Adverse Pregnancy Outcome (HAPO) study could be used to estimate insulin sensitivity during late pregnancy. RESEARCH DESIGN AND METHODS A total of 78 women enrolled in the HAPO study were recruited for this ancillary study...

journal_title：Diabetes care

authors： Radaelli T,Farrell KA,Huston-Presley L,Amini SB,Kirwan JP,McIntyre HD,Catalano PM

更新日期：2010-03-01 00:00:00

abstract：OBJECTIVE:This study examined the long-term consequences for offspring born to mothers with pregestational type 1 diabetes regarding mortality, hospital admissions, and medication. We also examined the association between HbA1c levels during pregnancy and mortality and incidence of hospital admissions. RESEARCH DESIGN...

journal_title：Diabetes care

authors： Knorr S,Stochholm K,Vlachová Z,Bytoft B,Clausen TD,Jensen RB,Juul S,Ovesen P,Damm P,Beck-Nielsen H,Jensen DM,Gravholt CH

更新日期：2015-05-01 00:00:00

abstract：OBJECTIVE:Previous studies have provided inconclusive results on the role of uric acid (UA) in risk prediction. Here we aimed to improve the power and precision of the predictive value of UA for the risk of decline in kidney function, cardiovascular events (CVEs), and mortality in patients with type 1 diabetes (T1D). ...

journal_title：Diabetes care

authors： Pilemann-Lyberg S,Hansen TW,Tofte N,Winther SA,Theilade S,Ahluwalia TS,Rossing P

更新日期：2019-06-01 00:00:00

abstract：OBJECTIVE:Sustained excess BMI increases the risk of type 1 diabetes (T1D) in autoantibody-positive relatives without diabetes of patients. We tested whether elevated BMI also accelerates the progression of islet autoimmunity before T1D diagnosis. RESEARCH DESIGN AND METHODS:We studied 706 single autoantibody-positive...

journal_title：Diabetes care

authors： Ferrara-Cook C,Geyer SM,Evans-Molina C,Libman IM,Becker DJ,Gitelman SE,Redondo MJ,Type 1 Diabetes TrialNet Study Group.

更新日期：2020-03-01 00:00:00

abstract：OBJECTIVE:Inflammatory processes have been implicated in the pathogenesis of painful neuropathy in rodents, but the relationship between inflammatory biomarkers and painful distal sensorimotor polyneuropathy (DSPN) has not been assessed in population-based studies. Therefore, we investigated whether circulating levels ...

journal_title：Diabetes care

authors： Herder C,Bongaerts BW,Rathmann W,Heier M,Kowall B,Koenig W,Thorand B,Roden M,Meisinger C,Ziegler D

更新日期：2015-01-01 00:00:00

abstract：OBJECTIVE:To examine whether cardiovascular autonomic neuropathy (CAN) is an independent risk factor of cardiovascular disease (CVD) events during DCCT/EDIC. RESEARCH DESIGN AND METHODS:Standardized cardiovascular autonomic reflex tests (R-R response to paced breathing, Valsalva maneuver, postural changes in blood pre...

journal_title：Diabetes care

authors： Pop-Busui R,Braffett BH,Zinman B,Martin C,White NH,Herman WH,Genuth S,Gubitosi-Klug R,DCCT\/EDIC Research Group.

更新日期：2017-01-01 00:00:00

abstract：OBJECTIVE:The Pima Indians of Arizona have the highest reported prevalences of obesity and non-insulin-dependent diabetes mellitus (NIDDM). In parallel with abrupt changes in lifestyle, these prevalences in Arizona Pimas have increased to epidemic proportions during the past decades. To assess the possible impact of th...

journal_title：Diabetes care

authors： Ravussin E,Valencia ME,Esparza J,Bennett PH,Schulz LO

更新日期：1994-09-01 00:00:00

abstract：OBJECTIVE:To assess the relationship between cigarette smoking and mortality among women with type 2 diabetes in the Nurses' Health Study cohort. RESEARCH DESIGN AND METHODS:The Nurses' Health Study, a prospective cohort of U.S. female registered nurses, included 7,401 women with type 2 diabetes diagnosed at baseline ...

journal_title：Diabetes care

authors： Al-Delaimy WK,Willett WC,Manson JE,Speizer FE,Hu FB

更新日期：2001-12-01 00:00:00

abstract：OBJECTIVE:To test the utility of homeostasis model assessment (HOMA) in predicting insulin sensitivity [x10(- 4) min(-1)/(microIU/ml)] in children and to develop and compare two new prediction equations for insulin sensitivity in children using demographic and anthropometric measures in the presence or absence of fasti...

journal_title：Diabetes care

authors： Huang TT,Johnson MS,Goran MI

更新日期：2002-07-01 00:00:00

abstract：OBJECTIVE:Ruboxistaurin selectively inhibits protein kinase C-beta and ameliorates kidney disease in animal models of diabetes. The purpose of this study was to evaluate the effects of ruboxistaurin on diabetic nephropathy in humans. RESEARCH DESIGN AND METHODS:A randomized, double-blind, placebo-controlled, multicent...

journal_title：Diabetes care

authors： Tuttle KR,Bakris GL,Toto RD,McGill JB,Hu K,Anderson PW

更新日期：2005-11-01 00:00:00

abstract：OBJECTIVE:To assess if low (1.25 mg) and/or standard (5 mg) doses of the ACE inhibitor ramipril could prevent progression of microalbuminuria (incipient diabetic nephropathy) in normotensive type 1 diabetic patients. RESEARCH DESIGN AND METHODS:This study, using a multicenter randomized placebo-controlled double-blind...

journal_title：Diabetes care

authors： O'Hare P,Bilbous R,Mitchell T,O' Callaghan CJ,Viberti GC,Ace-Inhibitor Trial to Lower Albuminuria in Normotensive Insulin-Dependent Subjects Study Group.

更新日期：2000-12-01 00:00:00

abstract：OBJECTIVE:Independent association of chronic kidney disease (CKD) and proliferative diabetic retinopathy (PDR) with cardiovascular disease (CVD) has not been established. In the Joslin 50-Year Medalist study, characterizing individuals with type 1 diabetes for 50 years or more, we examined the associations of CKD and P...

journal_title：Diabetes care

authors： Gordin D,Harjutsalo V,Tinsley L,Fickweiler W,Sun JK,Forsblom C,Amenta PS,Pober D,D'Eon S,Khatri M,Stillman IE,Groop PH,Keenan HA,King GL

更新日期：2018-04-01 00:00:00

abstract：OBJECTIVE:To determine the effect of a high-protein (HP) diet compared with a low-protein (LP) diet on weight loss, resting energy expenditure (REE), and the thermic effect of food (TEF) in subjects with type 2 diabetes during moderate energy restriction. RESEARCH DESIGN AND METHODS:In this study, 26 obese subjects wi...

journal_title：Diabetes care

authors： Luscombe ND,Clifton PM,Noakes M,Parker B,Wittert G

更新日期：2002-04-01 00:00:00

abstract：OBJECTIVE:While there is growing evidence on the effectiveness of structured care for diabetic patients in trial settings, standard population level evaluations may misestimate intervention benefits due to patient selection. In order to account for potential biases in measuring intervention benefits, we tested the impa...

journal_title：Diabetes care

authors： Chevreul K,Brunn M,Cadier B,Nolte E,Durand-Zaleski I

更新日期：2014-07-01 00:00:00

abstract：OBJECTIVE:To investigate the effects of metformin on glycemic control, insulin resistance, and risk factors for cardiovascular disease in NIDDM subjects from two ethnic groups (Caucasian and Asian) with different risks of cardiovascular disease. RESEARCH DESIGN AND METHODS:A total of 27 subjects with NIDDM (17 Caucasi...

journal_title：Diabetes care

authors： Nagi DK,Yudkin JS

更新日期：1993-04-01 00:00:00

abstract：OBJECTIVE:To determine 1) whether participants in the Spanish Diabetes Self-Management Program (SDSMP), when compared at 6 months to randomized control subjects, would demonstrate improvements in health status, health behaviors, and self-efficacy; and 2) whether SDSMP participants receiving monthly automated telephone ...

journal_title：Diabetes care

authors： Lorig K,Ritter PL,Villa F,Piette JD

更新日期：2008-03-01 00:00:00

abstract：OBJECTIVE:Oxidative stress has been shown to be increased in the postprandial period in patients with diabetes and has been implicated in the pathogenesis of micro- and macrovascular complications. The aim of this post hoc analysis was to assess the effects of pramlintide, an amylin analog shown to reduce postprandial ...

journal_title：Diabetes care

authors： Ceriello A,Piconi L,Quagliaro L,Wang Y,Schnabel CA,Ruggles JA,Gloster MA,Maggs DG,Weyer C

更新日期：2005-03-01 00:00:00

abstract：OBJECTIVE:This multicenter open-label clinical trial compared the efficacy and safety of repaglinide/troglitazone combination therapy, repaglinide monotherapy, and troglitazone monotherapy in type 2 diabetes that had been inadequately controlled by sulfonylureas, acarbose, or metformin alone. RESEARCH DESIGN AND METHO...

journal_title：Diabetes care

authors： Raskin P,Jovanovic L,Berger S,Schwartz S,Woo V,Ratner R

更新日期：2000-07-01 00:00:00

abstract：OBJECTIVE:To examine β-cell function across a spectrum of glycemia among Asian Indians, a population experiencing type 2 diabetes development at young ages despite low BMI. RESEARCH DESIGN AND METHODS:One-thousand two-hundred sixty-four individuals without known diabetes in the Diabetes Community Lifestyle Improvement...

journal_title：Diabetes care

authors： Staimez LR,Weber MB,Ranjani H,Ali MK,Echouffo-Tcheugui JB,Phillips LS,Mohan V,Narayan KM

更新日期：2013-09-01 00:00:00

abstract：OBJECTIVE:In the LixiLan-G trial, switching to iGlarLixi, a once-daily titratable fixed-ratio combination of insulin glargine 100 units/mL and the glucagon-like peptide 1 receptor agonist (GLP-1 RA) lixisenatide, improved glucose control in type 2 diabetes uncontrolled with GLP-1 RAs over 26 weeks versus continuing pri...

journal_title：Diabetes care

authors： Blonde L,Rosenstock J,Frias J,Birkenfeld AL,Niemoeller E,Souhami E,Ji C,Del Prato S,Aroda VR

更新日期：2021-01-19 00:00:00