Urinary estriols: are they of value in normoglycemic diabetic pregnancy?

abstract：OBJECTIVE:To investigate the possibility that leptin levels may be predictive of the risk of ischemic heart disease (IHD) through the relationship of leptin to body fat. RESEARCH DESIGN AND METHODS:The Quebec Cardiovascular Study cohort consisted of 2,103 French-Canadian men without IHD in 1985 who were followed until...

journal_title：Diabetes care

authors： Couillard C,Lamarche B,Mauriège P,Cantin B,Dagenais GR,Moorjani S,Lupien PJ,Després JP

更新日期：1998-05-01 00:00:00

abstract：OBJECTIVE:To study determinants of incident hyperglycemia in rural Indian mothers 6 years after delivery. RESEARCH DESIGN AND METHODS:The Pune Maternal Nutrition Study collected information in six villages near Pune on prepregnant characteristics and nutrition, physical activity, and glucose tolerance during pregnancy...

journal_title：Diabetes care

authors： Kulkarni SR,Fall CH,Joshi NV,Lubree HG,Deshpande VU,Pasarkar RV,Bhat DS,Naik SS,Yajnik CS

更新日期：2007-10-01 00:00:00

abstract：OBJECTIVE:To compare the efficacy, safety, and compliance of a nonremovable fiberglass cast boot and off-loading shoes in the treatment of diabetic plantar ulcers. RESEARCH DESIGN AND METHODS:Patients (n = 93) with noninfected, nonischemic plantar ulcers were included in this prospective nonrandomized study. Treatment...

journal_title：Diabetes care

authors： Ha Van G,Siney H,Hartmann-Heurtier A,Jacqueminet S,Greau F,Grimaldi A

更新日期：2003-10-01 00:00:00

abstract：OBJECTIVE:Differences in risk of erectile dysfunction (ED) by characteristics of diabetes among older men are not well understood. We examined the association of type and duration of diabetes with erectile function in men >50 years of age in a large prospective cohort study. RESEARCH DESIGN AND METHODS:Subjects includ...

journal_title：Diabetes care

authors： Bacon CG,Hu FB,Giovannucci E,Glasser DB,Mittleman MA,Rimm EB

更新日期：2002-08-01 00:00:00

abstract：OBJECTIVE:In this prospective, randomized, open trial, we compared the efficacy and safety of aspart insulin given subcutaneously at different time intervals to a standard low-dose intravenous (IV) infusion protocol of regular insulin in patients with uncomplicated diabetic ketoacidosis (DKA). RESEARCH DESIGN AND METH...

journal_title：Diabetes care

authors： Umpierrez GE,Cuervo R,Karabell A,Latif K,Freire AX,Kitabchi AE

更新日期：2004-08-01 00:00:00

abstract：OBJECTIVE:To determine whether food insecurity--the inability to reliably afford safe and nutritious food--is associated with poor glycemic control and whether this association is mediated by difficulty following a healthy diet, diabetes self-efficacy, or emotional distress related to diabetes. RESEARCH DESIGN AND MET...

journal_title：Diabetes care

authors： Seligman HK,Jacobs EA,López A,Tschann J,Fernandez A

更新日期：2012-02-01 00:00:00

abstract：OBJECTIVE:To examine cross-sectional associations of serum vitamin D [25-hydroxyvitamin D, 25(OH)D] concentration with insulin resistance (IR) and beta-cell dysfunction in 712 subjects at risk for type 2 diabetes. RESEARCH DESIGN AND METHODS:Serum 25(OH)D was determined using a chemiluminescence immunoassay. Insulin s...

journal_title：Diabetes care

authors： Kayaniyil S,Vieth R,Retnakaran R,Knight JA,Qi Y,Gerstein HC,Perkins BA,Harris SB,Zinman B,Hanley AJ

更新日期：2010-06-01 00:00:00

abstract：OBJECTIVE:Glycemic control (HbA(1c) [A1C]) is strongly associated with microvascular disease in individuals with diabetes, but its relation to macrovascular disease and atherosclerosis is less clear. This study examines the relationship between A1C, carotid intima-media thickness (IMT), and traditional cardiovascular r...

journal_title：Diabetes care

authors： Selvin E,Coresh J,Golden SH,Boland LL,Brancati FL,Steffes MW,Atherosclerosis risk in communities study.

更新日期：2005-08-01 00:00:00

abstract：OBJECTIVE:We examined the association of lactation duration with incident type 2 diabetes among women with a history of gestational diabetes mellitus (GDM). RESEARCH DESIGN AND METHODS:We monitored 4,372 women with a history of GDM participating in the Nurses' Health Study II for incident type 2 diabetes over 25 years...

journal_title：Diabetes care

authors： Ley SH,Chavarro JE,Li M,Bao W,Hinkle SN,Wander PL,Rich-Edwards J,Olsen S,Vaag A,Damm P,Grunnet LG,Mills JL,Hu FB,Zhang C

更新日期：2020-04-01 00:00:00

abstract：OBJECTIVE:To validate fasting indices of insulin sensitivity and secretion in a diverse pediatric population against gold standard estimates from euglycemic and hyperglycemic clamps. RESEARCH DESIGN AND METHODS:A total of 31 children (mean BMI 25.1 +/- 4.9 kg/m(2), mean age 8.7 +/- 1.4 years, 15 girls and 16 boys, 12 ...

journal_title：Diabetes care

authors： Uwaifo GI,Fallon EM,Chin J,Elberg J,Parikh SJ,Yanovski JA

更新日期：2002-11-01 00:00:00

abstract：:This review focuses on recent advances in molecular biology as they pertain to the insulin gene and diabetes mellitus. The structure of the human insulin gene is examined, and factors related to its normal functioning in the beta cells of the pancreas are explored. DNA polymorphisms near the insulin locus and their re...

journal_title：Diabetes care

authors： Permutt MA,Chirgwin J,Rotwein P,Giddings S

更新日期：1984-07-01 00:00:00

abstract：OBJECTIVE:Alterations of pancreatic β-cell cholesterol content may contribute to β-cell dysfunction. Two important determinants of intracellular cholesterol content are the ATP-binding cassette (ABC) transporters A1 (ABCA1) and -G1 (ABCG1). Whether genetic variation in ABCA1 and ABCG1 predicts risk of type 2 diabetes i...

journal_title：Diabetes care

authors： Schou J,Tybjærg-Hansen A,Møller HJ,Nordestgaard BG,Frikke-Schmidt R

更新日期：2012-12-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to prospectively assess the relation between red meat intake and incidence of type 2 diabetes. RESEARCH DESIGN AND METHODS:Over an average of 8.8 years, we evaluated 37,309 participants in the Women's Health Study aged >/=45 years who were free of cardiovascular disease, cancer, and...

journal_title：Diabetes care

authors： Song Y,Manson JE,Buring JE,Liu S

更新日期：2004-09-01 00:00:00

abstract：OBJECTIVE:Acarbose inhibits alpha-glucosidases of the small intestine and thus delays glucose release from complex carbohydrates. Therefore, its efficacy and acceptability as a first-line drug in non-insulin-dependent diabetes mellitus (NIDDM) insufficiently treated with diet alone was tested in a randomized double-bli...

journal_title：Diabetes care

authors： Hanefeld M,Fischer S,Schulze J,Spengler M,Wargenau M,Schollberg K,Fücker K

更新日期：1991-08-01 00:00:00

abstract：:Unexpected plasma glucose responses to different mixed meals fed to normal and diabetic volunteers have recently been reported. We have therefore examined in normal volunteers the effect of mixing carbohydrate foods of different glycemic indices (GIs) without the addition of fat and protein. The observed GI of the mix...

journal_title：Diabetes care

authors： Wolever TM,Nuttall FQ,Lee R,Wong GS,Josse RG,Csima A,Jenkins DJ

更新日期：1985-09-01 00:00:00

abstract：OBJECTIVE:To date no clinical trials have evaluated the role of dietary patterns on the incidence of microvascular diabetes complications. We hypothesized that a nutritional intervention based on the Mediterranean diet (MedDiet) would have greater protective effect on diabetic retinopathy and nephropathy than a low-fat...

journal_title：Diabetes care

authors： Díaz-López A,Babio N,Martínez-González MA,Corella D,Amor AJ,Fitó M,Estruch R,Arós F,Gómez-Gracia E,Fiol M,Lapetra J,Serra-Majem L,Basora J,Basterra-Gortari FJ,Zanon-Moreno V,Muñoz MÁ,Salas-Salvadó J,PREDIMED Study Inves

更新日期：2015-11-01 00:00:00

abstract：:Two-thirds of all deaths in developed countries are caused by the major noncommunicable diseases, e.g., cardiovascular disease, cancer, and non-insulin-dependent diabetes mellitus (NIDDM). There is increasing evidence that these diseases are a consequence of life-style change, and they have a number of risk factors in...

journal_title：Diabetes care

authors： Zimmet PZ

更新日期：1988-03-01 00:00:00

abstract：OBJECTIVE:Preclinical data suggest that linagliptin, a dipeptidyl peptidase-4 inhibitor, may lower urinary albumin excretion. The ability of linagliptin to lower albuminuria on top of renin-angiotensin-aldosterone system (RAAS) inhibition in humans was analyzed by pooling data from four similarly designed, 24-week, ran...

journal_title：Diabetes care

authors： Groop PH,Cooper ME,Perkovic V,Emser A,Woerle HJ,von Eynatten M

更新日期：2013-11-01 00:00:00

abstract：OBJECTIVE:To determine the association between triglyceride levels and lower-extremity amputation (LEA) risk in a large diabetic cohort. RESEARCH DESIGN AND METHODS:This is a 10-year survey follow-up study (from 1995-2006) of 28,701 diabetic patients with a baseline triglyceride measure. All patients were fully insure...

journal_title：Diabetes care

authors： Callaghan BC,Feldman E,Liu J,Kerber K,Pop-Busui R,Moffet H,Karter AJ

更新日期：2011-03-01 00:00:00

abstract：OBJECTIVE:Microalbuminuria can reflect the progress of microvascular complications and may be predictive of macrovascular disease in type 2 diabetes. The effect of intensive glycemic control on microalbuminuria in patients in the U.S. who have had type 2 diabetes for several years has not previously been evaluated. RE...

journal_title：Diabetes care

authors： Levin SR,Coburn JW,Abraira C,Henderson WG,Colwell JA,Emanuele NV,Nuttall FQ,Sawin CT,Comstock JP,Silbert CK

更新日期：2000-10-01 00:00:00

abstract：OBJECTIVE:Advanced glycation end products (AGEs) are a risk factor for diabetic complications. We have developed an assay method for N-(carboxymethyl)valine (CMV) of the hemoglobin (CMV-Hb), which is an AGE generated from HbA1c. Herein we describe the clinical utility of CMV-Hb measurement for the diagnosis of diabetic...

journal_title：Diabetes care

authors： Uchimura T,Nakano K,Hashiguchi T,Iwamoto H,Miura K,Yoshimura Y,Hanyu N,Hirata K,Imakuma M,Motomiya Y,Maruyama I

更新日期：2001-05-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to examine medication adherence and other self-management practices as potential determinants of higher glycemic risk among black relative to white patients. RESEARCH DESIGN AND METHODS:We used a retrospective, longitudinal repeated-measures design to model the contribution of m...

journal_title：Diabetes care

authors： Adams AS,Trinacty CM,Zhang F,Kleinman K,Grant RW,Meigs JB,Soumerai SB,Ross-Degnan D

更新日期：2008-05-01 00:00:00

abstract：OBJECTIVE:The risk of myocardial infarction (MI) in patients with diabetes is greater than for patients without diabetes. Consequently, prophylactic treatment is recommended for patients with diabetes and risk factors for ischemic heart disease. We aimed to estimate the risk of adverse cardiac events in patients with a...

journal_title：Diabetes care

authors： Olesen KKW,Madsen M,Egholm G,Thim T,Jensen LO,Raungaard B,Bøtker HE,Sørensen HT,Maeng M

更新日期：2017-08-01 00:00:00

abstract：OBJECTIVE:To determine the value of measuring serum triglyceride (TG) levels early in pregnancy for predicting late-gestation glucose tolerance and neonatal birth weight ratio (BWR) (birth weight corrected for gestational age). RESEARCH DESIGN AND METHODS:The relationships between morning nonfasting TG measured early ...

journal_title：Diabetes care

authors： Nolan CJ,Riley SF,Sheedy MT,Walstab JE,Beischer NA

更新日期：1995-12-01 00:00:00

abstract：OBJECTIVE:To provide evidence-based options on how to intensify basal insulin, we explored head-to-head prandial interventions in overweight patients with type 2 diabetes inadequately controlled on basal insulin glargine with or without 1-3 oral antidiabetic agents (OADs). RESEARCH DESIGN AND METHODS:Patients were ran...

journal_title：Diabetes care

authors： Rosenstock J,Guerci B,Hanefeld M,Gentile S,Aronson R,Tinahones FJ,Roy-Duval C,Souhami E,Wardecki M,Ye J,Perfetti R,Heller S,GetGoal Duo-2 Trial Investigators.

更新日期：2016-08-01 00:00:00

abstract：OBJECTIVE:To identify the clinical and genetic factors that explain why the rate of diabetes progression is highly variable between individuals following diagnosis of type 2 diabetes. RESEARCH DESIGN AND METHODS:We studied 5,250 patients with type 2 diabetes using comprehensive electronic medical records in Tayside, S...

journal_title：Diabetes care

authors： Zhou K,Donnelly LA,Morris AD,Franks PW,Jennison C,Palmer CN,Pearson ER

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:We evaluated the prevalence of endothelial dysfunction as measured by flow-mediated dilatation (FMD) of the brachial artery and carotid intima-media thickness (c-IMT) in relationship to vascular inflammatory biomarkers in preadolescent children with type 1 diabetes. RESEARCH DESIGN AND METHODS:We studied 21 ...

journal_title：Diabetes care

authors： Babar GS,Zidan H,Widlansky ME,Das E,Hoffmann RG,Daoud M,Alemzadeh R

更新日期：2011-03-01 00:00:00

abstract：OBJECTIVE:We aimed to determine the effect of elevated BMI over time on the progression to type 1 diabetes in youth. RESEARCH DESIGN AND METHODS:We studied 1,117 children in the TrialNet Pathway to Prevention cohort (autoantibody-positive relatives of patients with type 1 diabetes). Longitudinally accumulated BMI abov...

journal_title：Diabetes care

authors： Ferrara CT,Geyer SM,Liu YF,Evans-Molina C,Libman IM,Besser R,Becker DJ,Rodriguez H,Moran A,Gitelman SE,Redondo MJ,Type 1 Diabetes TrialNet Study Group.

更新日期：2017-05-01 00:00:00

abstract：:OBJECTIVE To assess the relationship between albuminuria, including elevation within the normal range, and decline in glomerular filtration rate (GFR) in diabetic patients. RESEARCH DESIGN AND METHODS A total of 5,449 Japanese diabetic patients were categorized according to sex and urinary albumin-to-creatinine ratio ...

journal_title：Diabetes care

authors： Babazono T,Nyumura I,Toya K,Hayashi T,Ohta M,Suzuki K,Kiuchi Y,Iwamoto Y

更新日期：2009-08-01 00:00:00

abstract：OBJECTIVE:To know the nutritional pattern of people with diabetes in Spain and that pattern's relationship with targets of metabolic control. RESEARCH DESIGN AND METHODS:The Diabetes Nutrition and Complications Trial (DNCT) is a prospective multicenter study designed to determine the nutritional behavior of diabetic p...

journal_title：Diabetes care

authors：

更新日期：1997-07-01 00:00:00