Serum xylosyltransferase activity in diabetic patients as a possible marker of reduced proteoglycan biosynthesis.

abstract：OBJECTIVE:Several meta-analyses of observational studies suggested that metformin use reduces cancer risk in type 2 diabetes. However, this result was not confirmed by the few available randomized controlled trials (RCTs), and many observational studies on metformin and cancer were potentially afflicted with time-relat...

journal_title：Diabetes care

authors： Kowall B,Rathmann W,Kostev K

更新日期：2015-01-01 00:00:00

abstract：OBJECTIVE:ABCC8 mutations cause neonatal diabetes mellitus that can be transient (TNDM) or, less commonly, permanent (PNDM); ∼90% of individuals can be treated with oral sulfonylureas instead of insulin. Previous studies suggested that people with ABCC8-PNDM require lower sulfonylurea doses and have milder neurological...

journal_title：Diabetes care

authors： Bowman P,Mathews F,Barbetti F,Shepherd MH,Sanchez J,Piccini B,Beltrand J,Letourneau-Freiberg LR,Polak M,Greeley SAW,Rawlins E,Babiker T,Thomas NJ,De Franco E,Ellard S,Flanagan SE,Hattersley AT,Neonatal Diabetes Internat

更新日期：2021-01-01 00:00:00

abstract：:Diabetes is more common in older adults, has a high prevalence in long-term care (LTC) facilities, and is associated with significant disease burden and higher cost. The heterogeneity of this population with regard to comorbidities and overall health status is critical to establishing personalized goals and treatments...

journal_title：Diabetes care

authors： Munshi MN,Florez H,Huang ES,Kalyani RR,Mupanomunda M,Pandya N,Swift CS,Taveira TH,Haas LB

更新日期：2016-02-01 00:00:00

abstract：OBJECTIVE:To determine whether adolescents with type 1 diabetes have left ventricular functional changes at rest and during acute exercise and whether these changes are affected by metabolic control and diabetes duration. RESEARCH DESIGN AND METHODS:The study evaluated 53 adolescents with type 1 diabetes and 22 contro...

journal_title：Diabetes care

authors： Gusso S,Pinto TE,Baldi JC,Robinson E,Cutfield WS,Hofman PL

更新日期：2012-10-01 00:00:00

abstract：OBJECTIVE:To determine maternal parameters with the strongest influence on fetal growth in different periods of pregnancies complicated by an abnormal glucose tolerance test (GTT). RESEARCH DESIGN AND METHODS:Retrospective study of 368 women with gestational diabetes mellitus (GDM; > or = 2 abnormal GTT values, n = 28...

journal_title：Diabetes care

authors： Schaefer-Graf UM,Kjos SL,Kilavuz O,Plagemann A,Brauer M,Dudenhausen JW,Vetter K

更新日期：2003-01-01 00:00:00

abstract：OBJECTIVE:To evaluate the association between self-reported diabetes and the risk of breast cancer (BC) and its interaction with moderate-intensity physical activity in pre- and postmenopausal Mexican women. RESEARCH DESIGN AND METHODS:A population-based case-control study was conducted using 1,000 incident case subje...

journal_title：Diabetes care

authors： Torres-Mejía G,Angeles-Llerenas A,Ortega-Olvera C,Lazcano-Ponce E,Ziv E,Pulido-Rodríguez J,García-Solis Mde J,Murillo-Zamora E,Vázquez-Lara J,Romieu I

更新日期：2012-12-01 00:00:00

abstract：OBJECTIVE:Pancreas size is reduced in patients at type 1 diabetes onset and in autoantibody (AAB)-positive donors without diabetes. We sought to determine whether pancreas volume (PV) imaging could improve understanding of the loss of pancreas size in first-degree relatives (FDRs) of patients with type 1 diabetes. We a...

journal_title：Diabetes care

authors： Campbell-Thompson ML,Filipp SL,Grajo JR,Nambam B,Beegle R,Middlebrooks EH,Gurka MJ,Atkinson MA,Schatz DA,Haller MJ

更新日期：2019-02-01 00:00:00

abstract：OBJECTIVE:To investigate whether peripheral neuropathy (PN), as part of the microangiopathic complex, affects bone mineral density (BMD) of the peripheral or the axial skeleton in patients with type 1 diabetes. RESEARCH DESIGN AND METHODS:Three study groups were examined. Group 1 comprised 21 males with type 1 diabete...

journal_title：Diabetes care

authors： Rix M,Andreassen H,Eskildsen P

更新日期：1999-05-01 00:00:00

abstract：OBJECTIVE:To longitudinally characterize changes in insulin sensitivity in obese women during and after pregnancy. RESEARCH DESIGN AND METHODS:Six glucose-tolerant obese women underwent a 4-h euglycemic-hyperinsulinemic (500-600 pmol/l) clamping during the second (22.5 +/- 2 weeks [mean +/- SD]) and third trimester (3...

journal_title：Diabetes care

authors： Sivan E,Chen X,Homko CJ,Reece EA,Boden G

更新日期：1997-09-01 00:00:00

abstract：OBJECTIVE:The relationship between coronary endothelial function and insulin resistance remains speculative. We sought to determine whether pioglitazone, an insulin-sensitizing peroxisome proliferator-activated receptor (PPAR)-gamma agonist, improves cardiac endothelial function in individuals with type 2 diabetes. RE...

journal_title：Diabetes care

authors： McMahon GT,Plutzky J,Daher E,Bhattacharyya T,Grunberger G,DiCarli MF

更新日期：2005-05-01 00:00:00

abstract：OBJECTIVE:To compare the glycemic profiles of patients with type 1 diabetes treated with either an implantable insulin pump or pancreas or islet transplantation by the means of the continuous glucose monitoring system (CGMS; Minimed, Sylmar, CA). RESEARCH DESIGN AND METHODS:The CGMS enabled recording of subcutaneous g...

journal_title：Diabetes care

authors： Kessler L,Passemard R,Oberholzer J,Benhamou PY,Bucher P,Toso C,Meyer P,Penfornis A,Badet L,Wolf P,Colin C,Morel P,Pinget M,GRAGIL Group.

更新日期：2002-12-01 00:00:00

abstract：OBJECTIVE:A common variant rs236918 in the PCSK7 gene has the strongest association with iron homeostasis and is related to insulin resistance. Dietary carbohydrate (CHO) modulates the genetic effect on insulin resistance. We examined whether 2-year weight-loss diets modify the effect of PCSK7 genetic variants on chang...

journal_title：Diabetes care

authors： Huang T,Huang J,Qi Q,Li Y,Bray GA,Rood J,Sacks FM,Qi L

更新日期：2015-03-01 00:00:00

abstract：OBJECTIVE:To assess the effect of mixing the insulin analog lispro (Humalog) with NPH (Humulin I) before injection on lispro's fast, short action profile. RESEARCH DESIGN AND METHODS:A total of 12 healthy volunteers received subcutaneous abdominal injections of 0.1 U/kg regular insulin and 0.2 U/kg NPH insulin as foll...

journal_title：Diabetes care

authors： Joseph SE,Korzon-Burakowska A,Woodworth JR,Evans M,Hopkins D,Janes JM,Amiel SA

更新日期：1998-12-01 00:00:00

abstract：:It is now possible to virtually normalize ambient blood glucose levels in insulin-dependent diabetic women during pregnancy. Successful programs have been developed that utilize home blood glucose monitoring, physiologic delivery of insulin, and quantitation of caloric intake carefully matched to insulin dosage. The r...

journal_title：Diabetes care

authors： Jovanovic L,Peterson CM

更新日期：1982-05-01 00:00:00

abstract：OBJECTIVE:A large proportion of vulvovaginal candidiasis (VVC) in diabetes is due to non-albicans Candida species such as C. glabrata and C. tropicalis. Observational studies indicate that diabetic patients with C. glabrata VVC respond poorly to azole drugs. We evaluated the response to oral fluconazole and boric acid ...

journal_title：Diabetes care

authors： Ray D,Goswami R,Banerjee U,Dadhwal V,Goswami D,Mandal P,Sreenivas V,Kochupillai N

更新日期：2007-02-01 00:00:00

abstract：OBJECTIVE:Little is known about medial arterial calcification (MAC) other than its association with age, sex, diabetes, and diabetes complications. Familial aggregation of this disorder was studied to determine the importance of potential genetic factors and to assess whether such familial aggregation was independent o...

journal_title：Diabetes care

authors： Narayan KM,Pettitt DJ,Hanson RL,Bennett PH,Fernandes RJ,De Courten M,Rose FA,Knowler WC

更新日期：1996-09-01 00:00:00

abstract：OBJECTIVE:Because readily available glycemic indicators are needed to guide clinical decision-making for intensification of diabetes therapy, our goals were to define the relationship between casual postprandial plasma glucose (cPPG) levels and HbA(1c) in patients with type 2 diabetes and to determine the predictive ch...

journal_title：Diabetes care

authors： El-Kebbi IM,Ziemer DC,Cook CB,Gallina DL,Barnes CS,Phillips LS

更新日期：2004-02-01 00:00:00

abstract：:Diabetes mellitus is a major public health problem and a leading cause of death, disability, and cost in the United States. We review the epidemiology of diabetes and its complications, the costs of diabetes, and discuss intervention strategies to reduce the burden of diabetes in the United States. ...

journal_title：Diabetes care

authors：

更新日期：1985-07-01 00:00:00

abstract：:In past studies on the psychological aspects of diabetes mellitus, symptoms of depression have been identified as the most common manifestation among diabetic patients. Other psychological manifestations have been anxiety, hypochondriasis, increased dependence and passivity, and poor self-image. Ten insulin-dependent ...

journal_title：Diabetes care

authors： Dupuis A

更新日期：1980-01-01 00:00:00

abstract：:Type 1 diabetes (T1D) and celiac disease (CeD) cluster in families and can occur in the same individual. Genetic loci have been associated with susceptibility to both diseases. Our aim was to explore the genetic differences between individuals developing both these diseases (double autoimmunity) versus those with only...

journal_title：Diabetes care

authors： Gutierrez-Achury J,Romanos J,Bakker SF,Kumar V,de Haas EC,Trynka G,Ricaño-Ponce I,Steck A,Type 1 Diabetes Genetics Consortium.,Chen WM,Onengut-Gumuscu S,Simsek S,Diabeter.,Rewers M,Mulder CJ,Liu E,Rich SS,Wijmenga C

更新日期：2015-10-01 00:00:00

abstract：OBJECTIVE:To examine the relationship between plasma IGF-1 and interleukin-6 (IL-6) levels in Caucasian nondiabetic subjects and evaluate the association of IGF-1 and IL-6 with the cardiometabolic risk factors characterizing metabolic syndrome (MetS). RESEARCH DESIGN AND METHODS:The study group consisted of 186 Caucas...

journal_title：Diabetes care

authors： Succurro E,Andreozzi F,Sciacqua A,Hribal ML,Perticone F,Sesti G

更新日期：2008-09-01 00:00:00

abstract：OBJECTIVE:Given the transient nature of exercise-induced improvements in insulin sensitivity, it has been speculated that daily exercise is preferred to maximize the benefits of exercise for glycemic control. The current study investigates the impact of daily exercise versus exercise performed every other day on glycem...

journal_title：Diabetes care

authors： van Dijk JW,Tummers K,Stehouwer CD,Hartgens F,van Loon LJ

更新日期：2012-05-01 00:00:00

abstract：OBJECTIVE:The Pima Indians of Arizona have the highest reported prevalences of obesity and non-insulin-dependent diabetes mellitus (NIDDM). In parallel with abrupt changes in lifestyle, these prevalences in Arizona Pimas have increased to epidemic proportions during the past decades. To assess the possible impact of th...

journal_title：Diabetes care

authors： Ravussin E,Valencia ME,Esparza J,Bennett PH,Schulz LO

更新日期：1994-09-01 00:00:00

abstract：OBJECTIVE:Comparative effectiveness research methods are used to compare the effect of four distinct glucose-control strategies on subsequent myocardial infarction and nephropathy in type 2 diabetes. RESEARCH DESIGN AND METHODS:A total of 58,000 adults with type 2 diabetes and A1C <7% (53 mmol/mol) while taking two or...

journal_title：Diabetes care

authors： Neugebauer R,Fireman B,Roy JA,O'Connor PJ

更新日期：2013-11-01 00:00:00

abstract：OBJECTIVE:The purpose of this paper is to estimate the impact of diabetes on survival among patients with first acute myocardial infarction, using data from the World Health Organization (WHO) Monitoring Trends and Determinants of Cardiovascular Disease (MONICA) Project in Newcastle, New South Wales, Australia. RESEAR...

journal_title：Diabetes care

authors： Chun BY,Dobson AJ,Heller RF

更新日期：1997-05-01 00:00:00

abstract：:Thirty-eight non-insulin-dependent diabetic patients within 130% of desirable body weight were given a 100-g oral glucose tolerance test (OGTT) at diagnosis and after at least 1 mo of dietary treatment with energy and carbohydrate restriction. Thirteen "responders" showed an improvement in fasting blood glucose, gluco...

journal_title：Diabetes care

authors： Sönksen PH,Lowy C,Perkins JR,Lim HS

更新日期：1984-05-01 00:00:00

abstract：OBJECTIVE:Several methods have been proposed to evaluate insulin sensitivity from the data obtained from the oral glucose tolerance test (OGTT). However, the validity of these indices has not been rigorously evaluated by comparing them with the direct measurement of insulin sensitivity obtained with the euglycemic insu...

journal_title：Diabetes care

authors： Matsuda M,DeFronzo RA

更新日期：1999-09-01 00:00:00

abstract：OBJECTIVE:To assess the relationship between subclinical cardiac dysfunction and aerobic exercise capacity (peak VO2) in adults with type 2 diabetes (T2D), a group at high risk of developing heart failure. RESEARCH DESIGN AND METHODS:Cross-sectional study. We prospectively enrolled a multiethnic cohort of asymptomatic...

journal_title：Diabetes care

authors： Gulsin GS,Henson J,Brady EM,Sargeant JA,Wilmot EG,Athithan L,Htike ZZ,Marsh AM,Biglands JD,Kellman P,Khunti K,Webb D,Davies MJ,Yates T,McCann GP

更新日期：2020-09-01 00:00:00

abstract：OBJECTIVE:We examined the association of lactation duration with incident type 2 diabetes among women with a history of gestational diabetes mellitus (GDM). RESEARCH DESIGN AND METHODS:We monitored 4,372 women with a history of GDM participating in the Nurses' Health Study II for incident type 2 diabetes over 25 years...

journal_title：Diabetes care

authors： Ley SH,Chavarro JE,Li M,Bao W,Hinkle SN,Wander PL,Rich-Edwards J,Olsen S,Vaag A,Damm P,Grunnet LG,Mills JL,Hu FB,Zhang C

更新日期：2020-04-01 00:00:00

abstract：OBJECTIVE:This study was performed to evaluate whether an additional dose of NPH insulin at lunchtime might overcome the deleterious effects of waning basal insulinemia on pre-dinner and evening glucose values during insulin lispro intensive therapy with once daily basal insulin at night. RESEARCH DESIGN AND METHODS:T...

journal_title：Diabetes care

authors： Stades AM,Hoekstra JB,van den Tweel I,Erkelens DW,Holleman F,STABILITY Study Group.

更新日期：2002-04-01 00:00:00