Glycemic control and complications in type II diabetes. Design of a feasibility trial. VA CS Group (CSDM)

abstract：:Because recent knowledge indicates that the distribution of fat deposits in men may be a better predictor of cardiovascular disease than the degree of obesity alone, some risk factors for atherosclerosis were evaluated in 51 middle-aged men with non-insulin-dependent diabetes mellitus. Abdominal adiposity (waist/hip r...

journal_title：Diabetes care

authors： Van Gaal L,Rillaerts E,Creten W,De Leeuw I

更新日期：1988-02-01 00:00:00

abstract：OBJECTIVE:The sulfonylurea (SU) glyburide may cause severe and prolonged episodes of hypoglycemia. We aimed at investigating the impact of glyburide on glucose counterregulatory hormones during stepwise hypoglycemic clamp studies. RESEARCH DESIGN AND METHODS:We performed stepwise hypoglycemic clamp studies in 16 healt...

journal_title：Diabetes care

authors： ter Braak EW,Appelman AM,van der Tweel I,Erkelens DW,van Haeften TW

更新日期：2002-01-01 00:00:00

abstract：OBJECTIVE:The International Diabetes Mellitus Practice Study is a 5-year survey documenting changes in diabetes treatment practice in developing regions. RESEARCH DESIGN AND METHODS:Logistic regression analysis was used to identify factors for achieving A1C <7% in 11,799 patients (1,898 type 1 diabetic and 9,901 type ...

journal_title：Diabetes care

authors： Chan JC,Gagliardino JJ,Baik SH,Chantelot JM,Ferreira SR,Hancu N,Ilkova H,Ramachandran A,Aschner P,IDMPS Investigators.

更新日期：2009-02-01 00:00:00

abstract：OBJECTIVE:Diabetes is one of the most common chronic diseases and a leading cause of morbidity and mortality in the U.S. Although our ability to treat diabetes and its associated complications has significantly improved, presentation with uncontrolled diabetes leading to ketoacidosis remains a significant problem. RES...

journal_title：Diabetes care

authors： Desai D,Mehta D,Mathias P,Menon G,Schubart UK

更新日期：2018-08-01 00:00:00

abstract：OBJECTIVE:To determine the effect of metformin on the acute metabolic response to submaximal exercise, the effect of exercise on plasma metformin concentrations, and the interaction between metformin and exercise on the subsequent response to a standardized meal. RESEARCH DESIGN AND METHODS:Ten participants with type ...

journal_title：Diabetes care

authors： Boulé NG,Robert C,Bell GJ,Johnson ST,Bell RC,Lewanczuk RZ,Gabr RQ,Brocks DR

更新日期：2011-07-01 00:00:00

abstract：OBJECTIVE:Repaglinide is a newly developed oral blood glucose-lowering agent that exerts its effect by stimulating insulin secretion. This multicenter study was designed to compare the efficacy and safety of this drug with glyburide in a 1-year randomized double-blind study of outpatients with type 2 diabetes. RESEARC...

journal_title：Diabetes care

authors： Wolffenbuttel BH,Landgraf R

更新日期：1999-03-01 00:00:00

abstract：OBJECTIVE:N-acetylglucosamine/galactosamine (GlycA) and sialic acid (GlycB) moieties of glycosylated serum proteins are nonspecific measures of inflammation, but conclusive data on their relationship with insulin resistance or insulin secretion are missing. Therefore, we aimed to examine the relation of GlycA, GlycB, a...

journal_title：Diabetes care

authors： Lorenzo C,Festa A,Hanley AJ,Rewers MJ,Escalante A,Haffner SM

更新日期：2017-03-01 00:00:00

abstract：:The acute effect of sulfonylurea drugs during long-term treatment was evaluated in two separate studies. In the first study, the levels of plasma glucose, insulin, and C-peptide were measured after intake of 10 mg glyburide alone or together with a standardized mixed meal in 10 non-insulin-dependent diabetes mellitus ...

journal_title：Diabetes care

authors： Faber OK,Beck-Nielsen H,Binder C,Butzer P,Damsgaard EM,Froland F,Hjollund E,Lindskov HO,Melander A,Pedersen O

更新日期：1990-08-01 00:00:00

abstract：OBJECTIVE:Differences in risk of erectile dysfunction (ED) by characteristics of diabetes among older men are not well understood. We examined the association of type and duration of diabetes with erectile function in men >50 years of age in a large prospective cohort study. RESEARCH DESIGN AND METHODS:Subjects includ...

journal_title：Diabetes care

authors： Bacon CG,Hu FB,Giovannucci E,Glasser DB,Mittleman MA,Rimm EB

更新日期：2002-08-01 00:00:00

abstract：OBJECTIVE:To identify the clinical and genetic factors that explain why the rate of diabetes progression is highly variable between individuals following diagnosis of type 2 diabetes. RESEARCH DESIGN AND METHODS:We studied 5,250 patients with type 2 diabetes using comprehensive electronic medical records in Tayside, S...

journal_title：Diabetes care

authors： Zhou K,Donnelly LA,Morris AD,Franks PW,Jennison C,Palmer CN,Pearson ER

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:Previous reviews of the effect of oral antidiabetic (OAD) agents on A1C levels summarized studies with varying designs and methodological approaches. Using predetermined methodological criteria, we evaluated the effect of OAD agents on A1C levels. RESEARCH DESIGN AND METHODS:The Excerpta Medica (EMBASE), the...

journal_title：Diabetes care

authors： Sherifali D,Nerenberg K,Pullenayegum E,Cheng JE,Gerstein HC

更新日期：2010-08-01 00:00:00

abstract：OBJECTIVE:To assess long-term metabolic and immunological follow-up of microencapsulated human islet allografts in nonimmunosuppressed patients with type 1 diabetes (T1DM). RESEARCH DESIGN AND METHODS:Four nonimmunosuppressed patients, with long-standing T1DM, received intraperitoneal transplant (TX) of microencapsula...

journal_title：Diabetes care

authors： Basta G,Montanucci P,Luca G,Boselli C,Noya G,Barbaro B,Qi M,Kinzer KP,Oberholzer J,Calafiore R

更新日期：2011-11-01 00:00:00

abstract：OBJECTIVE:A combined analysis of whether islet cell autoantibodies (ICAs) are cross-reactive with mouse pancreas, with glutamate decarboxylase (GAD) antibodies, and with 64K antibodies was performed in a large sample of recently diagnosed type I diabetic patients. The disappearance rates of these different autoantibodi...

journal_title：Diabetes care

authors： Chaillous L,Delamaire M,Martignat L,Maugendre D,Marre M,Mathieu E,Limal JM,Charbonnel B,Allannic H,Saï P

更新日期：1994-10-01 00:00:00

abstract：OBJECTIVE:There is enough evidence that physical activity is an effective therapeutic tool in the management of type 2 diabetes. The present study was designed to validate a counseling strategy that could be used by physicians in their daily outpatient practice to promote the adoption and maintenance of physical activi...

journal_title：Diabetes care

authors： Di Loreto C,Fanelli C,Lucidi P,Murdolo G,De Cicco A,Parlanti N,Santeusanio F,Brunetti P,De Feo P

更新日期：2003-02-01 00:00:00

abstract：OBJECTIVE:To determine the prevalence of macroalbuminuria and to describe the clinical and renal pathological changes associated with macroalbuminuria in a population of Canadian First Nation children and adolescents with type 2 diabetes. RESEARCH DESIGN AND METHODS:We conducted a retrospective chart review at a singl...

journal_title：Diabetes care

authors： Sellers EA,Blydt-Hansen TD,Dean HJ,Gibson IW,Birk PE,Ogborn M

更新日期：2009-05-01 00:00:00

abstract：OBJECTIVE:To determine the proportion of patients with gestational diabetes mellitus (GDM) who have serological characteristics typical of IDDM. RESEARCH DESIGN AND METHODS:Islet cell antibodies (ICAs), insulin autoantibodies (IAAs), GAD65, and IA-2 antibodies were measured in 145 pregnant women with GDM, 33 with impa...

journal_title：Diabetes care

authors： Dozio N,Beretta A,Belloni C,Castiglioni M,Rosa S,Bosi E,Bonifacio E

更新日期：1997-01-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to estimate how much at-risk individuals are willing to pay for type 2 diabetes primary prevention programs. RESEARCH DESIGN AND METHODS:An Internet-based, choice-format conjoint survey was presented to individuals at elevated risk for type 2 diabetes. Hypothetical diabetes risk...

journal_title：Diabetes care

authors： Johnson FR,Manjunath R,Mansfield CA,Clayton LJ,Hoerger TJ,Zhang P

更新日期：2006-06-01 00:00:00

abstract：OBJECTIVE:To examine racial variation in the poor control of GHb, a GHb value >9.5%, or GHb not tested in 1999 among Medicare beneficiaries aged 65-75 years enrolled in managed care plans. RESEARCH DESIGN AND METHODS:The National Committee on Quality Assurance provides person-level data regarding diabetes care service...

journal_title：Diabetes care

authors： McBean AM,Huang Z,Virnig BA,Lurie N,Musgrave D

更新日期：2003-12-01 00:00:00

abstract：:Type 2 diabetes is a chronic disease with disabling micro- and macrovascular complications that lead to excessive morbidity and premature mortality. It affects hundreds of millions of people and imposes an undue economic burden on populations across the world. Although insulin resistance and insulin secretory defects ...

journal_title：Diabetes care

authors： Mudaliar S,Polidori D,Zambrowicz B,Henry RR

更新日期：2015-12-01 00:00:00

abstract：OBJECTIVE:The prevalence of systemic hypertension is increased in patients with diabetes. In this prospective, randomized, crossover clinical trial, we assessed antihypertensive effects of chronic intermittent intravenous insulin therapy (CIIIT) on insulin-dependent diabetes mellitus (IDDM) subjects with hypertension a...

journal_title：Diabetes care

authors： Aoki TT,Grecu EO,Prendergast JJ,Arcangeli MA,Meisenheimer R

更新日期：1995-09-01 00:00:00

abstract：OBJECTIVE:To evaluate glucose-based community screening for diabetes with regard to detection rate. RESEARCH DESIGN AND METHODS:A retrospective analysis of a community-screening questionnaire data base that included a screening for blood glucose. Referred subjects had fasting glucose levels > 6.4 mM (115 mg/dl) or pos...

journal_title：Diabetes care

authors： Newman WP,Nelson R,Scheer K

更新日期：1994-05-01 00:00:00

abstract：OBJECTIVE:To characterize physiologic subtypes of gestational diabetes mellitus (GDM). RESEARCH DESIGN AND METHODS:Insulin sensitivity and secretion were estimated in 809 women at 24-30 weeks' gestation, using oral glucose tolerance test-based indices. In women with GDM (8.3%), defects in insulin sensitivity or secret...

journal_title：Diabetes care

authors： Powe CE,Allard C,Battista MC,Doyon M,Bouchard L,Ecker JL,Perron P,Florez JC,Thadhani R,Hivert MF

更新日期：2016-06-01 00:00:00

abstract：OBJECTIVE:To determine whether, after adjustment for glycemia and other selected covariates, hemoglobin A1c (HbA1c) differed among adults from six Hispanic/Latino heritage groups (Central American, Cuban, Dominican, Mexican, Puerto Rican, and South American) and between Hispanic/Latino and non-Hispanic white adults wit...

journal_title：Diabetes care

authors： Avilés-Santa ML,Hsu LL,Arredondo M,Menke A,Werner E,Thyagarajan B,Heiss G,Teng Y,Schneiderman N,Giachello AL,Gallo LC,Talavera GA,Cowie CC

更新日期：2016-06-01 00:00:00

abstract：:It had been suggested that long-term lowering of blood glucose by sulfonylureas in non-insulin-dependent (NIDD) diabetes is not due to a sustained increase in insulin secretion. We have re-examined this question. Thirteen nonobese NIDD patients not controlled on diet alone were studied prospectively on treatment with ...

journal_title：Diabetes care

authors： Elkeles RS,Heding LG,Paisey RB

更新日期：1982-07-01 00:00:00

abstract：OBJECTIVE:People with diabetes have an increased risk of coronary artery disease (CAD). An unanswered question is what portion of CAD can be attributed to insulin resistance, related metabolic variables, and other known CAD risk factors. RESEARCH DESIGN AND METHODS:The Archimedes model was used to estimate the proport...

journal_title：Diabetes care

authors： Eddy D,Schlessinger L,Kahn R,Peskin B,Schiebinger R

更新日期：2009-02-01 00:00:00

abstract：:Biosynthetic human insulin (BHI) and purified pork insulin (PPI) were compared for binding properties and stimulatory effect on 2-deoxyglucose transport in isolated rat fat cells. No difference between these types of insulin could be demonstrated. ...

journal_title：Diabetes care

authors： Wieringa T,van Putten JP,Van Dijk-Besling M,Krans HM

更新日期：1981-03-01 00:00:00

abstract：:A higher prevalence of stroke is found in the patient with both diagnosed and undiagnosed diabetes and glucose intolerance. Because of local cerebral acidosis caused by ischemia and hyperglycemia, morbidity and mortality from a stroke are increased. Most studies show that individuals with admission serum glucose > 120...

journal_title：Diabetes care

authors： Bell DS

更新日期：1994-03-01 00:00:00

abstract：OBJECTIVE:Patients with diabetes have a higher case fatality rate in myocardial infarction (MI) or stroke than those without diabetes: that is, MI and stroke are more often fatal if diabetes is present. We investigated whether the risk of MI or stroke being fatal in type 2 diabetes can be estimated using information av...

journal_title：Diabetes care

authors： Stevens RJ,Coleman RL,Adler AI,Stratton IM,Matthews DR,Holman RR

更新日期：2004-01-01 00:00:00

abstract：OBJECTIVE:Diabetes Prevention Program (DPP) participants randomized to the intensive lifestyle intervention (ILS) had significantly reduced risk of diabetes compared with placebo participants. We explored the contribution of changes in weight, diet, and physical activity on the risk of developing diabetes among ILS par...

journal_title：Diabetes care

authors： Hamman RF,Wing RR,Edelstein SL,Lachin JM,Bray GA,Delahanty L,Hoskin M,Kriska AM,Mayer-Davis EJ,Pi-Sunyer X,Regensteiner J,Venditti B,Wylie-Rosett J

更新日期：2006-09-01 00:00:00

abstract：OBJECTIVE:To determine whether an educational intervention for medical house staff improves blood glucose (BG) in hospitalized patients. RESEARCH DESIGN AND METHODS:All 116 medicine residents at an academic medical center were assigned to online or classroom training on inpatient dysglycemia in fall 2008. Both groups ...

journal_title：Diabetes care

authors： Tamler R,Green DE,Skamagas M,Breen TL,Looker HC,Babyatsky M,Leroith D

更新日期：2011-08-01 00:00:00