Inhibition of pancreatic glucagon responses to arginine by human insulin (recombinant DNA) and purified porcine insulin in normal and diabetic subjects.

abstract：OBJECTIVE:To determine the frequency of IDDM risk-associated HLA-DQ beta alleles in New Zealanders with IDDM and nondiabetic control subjects, and to examine these as susceptibility markers in relation to IDDM incidence. RESEARCH DESIGN AND METHODS:HLA-DQ beta typing was conducted in 55 juvenile-onset IDDM subjects di...

journal_title：Diabetes care

authors： Forbes LV,Brown LJ,Scott RS

更新日期：1993-08-01 00:00:00

abstract：OBJECTIVE:To relate deterioration in kidney function to some potential cardiovascular risk factors in type II diabetic patients. RESEARCH DESIGN AND METHODS:Twenty-four normoalbuminuric and 13 microalbuminuric patients completed a 3.4-yr prospective observational study. Glomerular filtration rate, urinary albumin excr...

journal_title：Diabetes care

authors： Nielsen S,Schmitz A,Rehling M,Mogensen CE

更新日期：1993-11-01 00:00:00

abstract：:OBJECTIVE Using the clamp technique, youths with a clinical diagnosis of type 2 diabetes (CDx-type 2 diabetes) and positive pancreatic autoantibodies (Ab(+)) were shown to have severe impairment in insulin secretion and less insulin resistance than their peers with negative antibodies (Ab(-)). In this study, we invest...

journal_title：Diabetes care

authors： Tfayli H,Bacha F,Gungor N,Arslanian S

更新日期：2010-03-01 00:00:00

abstract：OBJECTIVE:The objectives of this study were to compare early predictive marker of the metabolic syndrome with proopiomelanocortin (POMC) methylation status and to determine the association among birth weight, ponderal index, and cord blood methylation status. RESEARCH DESIGN AND METHODS:We collected pregnancy outcome ...

journal_title：Diabetes care

authors： Yoo JY,Lee S,Lee HA,Park H,Park YJ,Ha EH,Kim YJ

更新日期：2014-01-01 00:00:00

abstract：:The goal of this study was to evaluate a program of resistance weight training on cardiovascular risk factors, blood glucose management, and overall strength in diabetic subjects. A randomized crossover design was performed on eight male type I (insulin-dependent) diabetic subjects (mean +/- SD age 31 +/- 3.5 yr, heig...

journal_title：Diabetes care

authors： Durak EP,Jovanovic-Peterson L,Peterson CM

更新日期：1990-10-01 00:00:00

abstract：OBJECTIVE:The objective of this analysis was to evaluate the impact of several classes of oral antihyperglycemic therapy relative to sulfonylurea monotherapy on all-cause mortality among a cohort of patients with diabetes from the Veterans Health Administration (VHA). RESEARCH DESIGN AND METHODS:A retrospective cohort...

journal_title：Diabetes care

authors： Kahler KH,Rajan M,Rhoads GG,Safford MM,Demissie K,Lu SE,Pogach LM

更新日期：2007-07-01 00:00:00

abstract：OBJECTIVE:Despite being a safe, effective therapy for lowering cardiovascular risk, only 20% of diabetic patients were using aspirin in the early 1990s. This study examines current physician practices and the use of aspirin therapy by individuals with diabetes. RESEARCH DESIGN AND METHODS:A random sample of diabetic p...

journal_title：Diabetes care

authors： Krein SL,Vijan S,Pogach LM,Hogan MM,Kerr EA

更新日期：2002-06-01 00:00:00

abstract：OBJECTIVE:To summarize the efficacy of metformin in reducing BMI and cardiometabolic risk in obese children and adolescents without diabetes. RESEARCH DESIGN AND METHODS:We performed a systematic review and meta-analysis of randomized controlled trials (RCTs). Double-blind RCTs of > or =6 months duration in obese subj...

journal_title：Diabetes care

authors： Park MH,Kinra S,Ward KJ,White B,Viner RM

更新日期：2009-09-01 00:00:00

abstract：OBJECTIVE:Because a pseudonormal pattern of ventricular filling has never been considered in studies that reported a prevalence of left ventricular diastolic dysfunction (LVDD) between 20 and 40%, our aim was to more completely evaluate the prevalence of LVDD in subjects with diabetes. RESEARCH DESIGN AND METHODS:We s...

journal_title：Diabetes care

authors： Poirier P,Bogaty P,Garneau C,Marois L,Dumesnil JG

更新日期：2001-01-01 00:00:00

abstract：OBJECTIVE:Stress hyperglycemia has been associated with increased mortality in patients with myocardial infarction (MI). We examined the association between plasma glucose levels, circulating inflammatory markers, T-cell activation, and functional cardiac outcome in patients with first MI. RESEARCH DESIGN AND METHODS:...

journal_title：Diabetes care

authors： Marfella R,Siniscalchi M,Esposito K,Sellitto A,De Fanis U,Romano C,Portoghese M,Siciliano S,Nappo F,Sasso FC,Mininni N,Cacciapuoti F,Lucivero G,Giunta R,Verza M,Giugliano D

更新日期：2003-11-01 00:00:00

abstract：:Sixty-two subjects having either insulin-dependent or non-insulin-dependent diabetes completed a randomized, double-blind study comparing effects of aspartame or a placebo on blood glucose control. Twenty-nine subjects consumed 2.7 g aspartame per day for 18 wk, given as aspartame-containing capsules with meals, while...

journal_title：Diabetes care

authors： Nehrling JK,Kobe P,McLane MP,Olson RE,Kamath S,Horwitz DL

更新日期：1985-09-01 00:00:00

abstract：:To assess the possible value of the use of high-purity pork insulin (HPPI) in the United States, the serum insulin (I), pancreatic polypeptide (PP), glucagon (G), and somatostatin (SRIF) antibody binding characteristics have been determined in 90 conventional insulin-treated diabetic subjects and related to their degr...

journal_title：Diabetes care

authors： Asplin CM,Hollander P,Pecoraro RE,Brodsky J,Palmer JP

更新日期：1981-05-01 00:00:00

abstract：OBJECTIVE:Blood pressure ranges associated with cardiovascular disease (CVD) events in advanced type 2 diabetes are not clear. Our objective was to determine whether baseline and follow-up (On-Study) systolic blood pressure (SBP), diastolic blood pressure (DBP), and SBP combined with DBP predict CVD events in the Veter...

journal_title：Diabetes care

authors： Anderson RJ,Bahn GD,Moritz TE,Kaufman D,Abraira C,Duckworth W,VADT Study Group.

更新日期：2011-01-01 00:00:00

abstract：OBJECTIVE:To quantify age-related variability of insulin needs during day and night closed-loop insulin delivery. RESEARCH DESIGN AND METHODS:We retrospectively analyzed data from hybrid closed-loop studies involving young children (1-6 years old, n = 20), children (7-12 years, n = 21), adolescents (13-17 years, n = 1...

journal_title：Diabetes care

authors： Dovc K,Boughton C,Tauschmann M,Thabit H,Bally L,Allen JM,Acerini CL,Arnolds S,de Beaufort C,Bergenstal RM,Campbell F,Criego A,Dunger DB,Elleri D,Evans ML,Fröhlich-Reiterer E,Hofer S,Kapellen T,Leelarathna L,Pieber T

更新日期：2019-07-01 00:00:00

abstract：:Compared with control subjects, non-insulin-dependent diabetes mellitus (NIDDM) subjects had both quantitative and qualitative abnormalities in blood insulin and glucose concentrations. The purpose of this study was to determine whether and to what extent normally observed multiphasic patterns of insulin and glucose r...

journal_title：Diabetes care

authors： Calles-Escandon J,Jaspan J,Robbins DC

更新日期：1989-11-01 00:00:00

abstract：OBJECTIVE:Antioxidant trials have not demonstrated efficacy in slowing cardiovascular disease but could not rule out benefit for specific patient subgroups. Antioxidant therapy reduces LDL oxidizability in haptoglobin 1 allele homozygotes (Hp 1-1), but not in individuals with the haptoglobin 2 allele (Hp 2-1 or Hp 2-2)...

journal_title：Diabetes care

authors： Levy AP,Friedenberg P,Lotan R,Ouyang P,Tripputi M,Higginson L,Cobb FR,Tardif JC,Bittner V,Howard BV

更新日期：2004-04-01 00:00:00

abstract：OBJECTIVE:To examine mortality rates and causes of death among subjects diagnosed with type 1 diabetes aged

journal_title：Diabetes care

authors： Feltbower RG,Bodansky HJ,Patterson CC,Parslow RC,Stephenson CR,Reynolds C,McKinney PA

更新日期：2008-05-01 00:00:00

abstract：OBJECTIVE:The goal of this study was to determine whether the haptoglobin (Hp) genotype was predictive of restenosis and major adverse cardiac events (MACEs) after percutaneous transluminal coronary angioplasty (PTCA) in individuals with diabetes. RESEARCH DESIGN AND METHODS:A consecutive series of 935 diabetic patien...

journal_title：Diabetes care

authors： Roguin A,Koch W,Kastrati A,Aronson D,Schomig A,Levy AP

更新日期：2003-09-01 00:00:00

abstract：OBJECTIVE:To compare the prevalence of lumbar spondylolytic spondylolisthesis (LSS) in nondiabetic and diabetic subjects. RESEARCH DESIGN AND METHODS:A cross-sectional study of 1,147 randomly selected nondiabetic subjects and 892 non-insulin-dependent diabetes mellitus (NIDDM) patients, 45-64 years of age. LSS was dia...

journal_title：Diabetes care

authors： Virta L,Rönnemaa T,Laakso M

更新日期：1994-06-01 00:00:00

abstract：OBJECTIVE:To estimate the health-related quality of life (HRQOL) and treatment satisfaction for patients with type 2 diabetes in the Netherlands and to examine which patient characteristics are associated with quality of life and treatment satisfaction. RESEARCH DESIGN AND METHODS:For a sample of 1,348 type 2 diabetes...

journal_title：Diabetes care

authors： Redekop WK,Koopmanschap MA,Stolk RP,Rutten GE,Wolffenbuttel BH,Niessen LW

更新日期：2002-03-01 00:00:00

abstract：OBJECTIVE:To evaluate the brain's responses to painful visceral and somatic stimuli in diabetic patients with gastrointestinal symptoms. RESEARCH DESIGN AND METHODS:The sensitivity to electrical esophageal and median nerve stimulations was assessed in 15 healthy volunteers and 14 type 1 diabetic patients with autonomi...

journal_title：Diabetes care

authors： Frøkjaer JB,Søfteland E,Graversen C,Dimcevski G,Egsgaard LL,Arendt-Nielsen L,Drewes AM

更新日期：2009-07-01 00:00:00

abstract：OBJECTIVE:To assess the impact of bariatric surgery (BS) on incident microvascular complications of diabetes-related foot disease (DFD), sight-threatening diabetic retinopathy (STDR), and chronic kidney disease (CKD) in patients with type 2 diabetes and obesity. RESEARCH DESIGN AND METHODS:A retrospective matched, con...

journal_title：Diabetes care

authors： Singh P,Adderley N,Subramanian A,Gokhale K,Singhal R,Toulis KA,Bellary S,Nirantharakumar K,Tahrani AA

更新日期：2021-01-01 00:00:00

abstract：:OBJECTIVE- We examined the influence of a moderately elevated serum ferritin level at entry to care on the risk of gestational diabetes mellitus (GDM) and a possible mechanism (increased iron stores versus inflammation). RESEARCH DESIGN AND METHODS- In a prospective observational study with 1,456 healthy pregnant wome...

journal_title：Diabetes care

authors： Chen X,Scholl TO,Stein TP

更新日期：2006-05-01 00:00:00

abstract：OBJECTIVE:Glycated hemoglobin (HbA1c) is positively associated with cardiovascular disease (CVD), although evidence is primarily observational. Mendelian randomization studies have only examined its relation with subtypes of CVD. We examined the relation of HbA1c with CVD and its subtypes in the UK Biobank using Mendel...

journal_title：Diabetes care

authors： Au Yeung SL,Luo S,Schooling CM

更新日期：2018-09-01 00:00:00

abstract：OBJECTIVE:In patients with type 2 diabetes, microalbuminuria is associated with an increase in predominantly cardiovascular mortality. Considerable interindividual variability in the rate of progression of microalbuminuria exists. The prognostic significance of rate of progression of microalbuminuria with regard to car...

journal_title：Diabetes care

authors： Spoelstra-de Man AM,Brouwer CB,Stehouwer CD,Smulders YM

更新日期：2001-12-01 00:00:00

abstract：OBJECTIVE:To compare lifestyle factors, cardiovascular risk factors, and coronary artery calcium (CAC) and abdominal aortic calcium (AAC) levels in Hispanic and non-Hispanic white (NHW) individuals with type 2 diabetes. RESEARCH DESIGN AND METHODS:We recently demonstrated in a small group of nonreferred, healthy, nond...

journal_title：Diabetes care

authors： Reaven PD,Sacks J,Investigators for the Veterans Affairs Cooperative Study of Glycemic Control and Complications in Diabetes Mellitus Type 2.

更新日期：2004-05-01 00:00:00

abstract：:The results of uncontrolled trials in immunomodulation of insulin-dependent diabetes mellitus (IDDM) led to randomized controlled trials in Canada and Europe. In the Canadian open study, the rate of clinical remissions (target control of glycemia maintained with less than or equal to 0.15 U.kg-1.day-1 insulin) was une...

journal_title：Diabetes care

authors： Dupré J,Stiller CR,Gent M,Donner A,von Graffenried B,Heinrichs D,Jenner M,Keown P,Mahon J,Martell R

更新日期：1988-11-01 00:00:00

abstract：:The risk of severe hypoglycemia associated with the particular therapeutic approach of two University hospitals was assessed in 96% of all patients with insulin-dependent diabetes mellitus (IDDM) who had been admitted during a period of almost 3 yr to the diabetic wards of two hospitals and who participated in a struc...

journal_title：Diabetes care

authors： Mühlhauser I,Berger M,Sonnenberg G,Koch J,Jörgens V,Schernthaner G,Scholz V,Pädagogin D

更新日期：1985-05-01 00:00:00

abstract：OBJECTIVE:To examine the relationships between plasma 25-hydroxyvitamin D [25(OH)D] and in vivo insulin sensitivity and β-cell function relative to insulin sensitivity, disposition index (DI), in black and white youth. RESEARCH DESIGN AND METHODS:Plasma 25(OH)D concentrations were analyzed in banked specimens in healt...

journal_title：Diabetes care

authors： Rajakumar K,de las Heras J,Lee S,Holick MF,Arslanian SA

更新日期：2012-03-01 00:00:00

abstract：OBJECTIVE:Cardiomyopathy is noted in up to 40% of infants of diabetic mothers, and the exact mechanisms are unknown. The aim of this study was to determine whether fetal serum markers of cardiac function differ between normal and type 1 diabetic pregnancies and to examine the relationship between these markers and feta...

journal_title：Diabetes care

authors： Russell NE,Higgins MF,Amaruso M,Foley M,McAuliffe FM

更新日期：2009-11-01 00:00:00