The Impact of Glycated Hemoglobin (HbA1c) on Cardiovascular Disease Risk: A Mendelian Randomization Study Using UK Biobank.

abstract：OBJECTIVE:In type 1 diabetes (T1D), the course of microalbuminuria is unpredictable and timing of glomerular filtration rate (GFR) loss is uncertain. Thus, there is a need to identify the risk factors associated with the development of more advanced stages of kidney disease through large, long-term systematic analysis....

journal_title：Diabetes care

authors： Perkins BA,Bebu I,de Boer IH,Molitch M,Tamborlane W,Lorenzi G,Herman W,White NH,Pop-Busui R,Paterson AD,Orchard T,Cowie C,Lachin JM,Diabetes Control and Complications Trial (DCCT)\/Epidemiology of Diabetes Interventions and Com

更新日期：2019-05-01 00:00:00

abstract：OBJECTIVE:To establish quantitative characteristics of lifestyle counseling documentation associated with improved glycemic control in patients with diabetes. RESEARCH DESIGN AND METHODS:We retrospectively studied 10,870 hyperglycemic (HbA1c ≥7.0% [53 mmol/mol]) adults with diabetes followed at primary care practices ...

journal_title：Diabetes care

authors： Hosomura N,Goldberg SI,Shubina M,Zhang M,Turchin A

更新日期：2015-07-01 00:00:00

abstract：OBJECTIVE:To evaluate the efficacy and safety of lixisenatide versus placebo on glycemic control in older patients with type 2 diabetes uncontrolled on their current antidiabetic treatment. RESEARCH DESIGN AND METHODS:In this phase III, double-blind, randomized, placebo-controlled, two-arm, parallel-group, multicenter...

journal_title：Diabetes care

authors： Meneilly GS,Roy-Duval C,Alawi H,Dailey G,Bellido D,Trescoli C,Manrique Hurtado H,Guo H,Pilorget V,Perfetti R,Simpson H,GetGoal-O Trial Investigators.

更新日期：2017-04-01 00:00:00

abstract：OBJECTIVE:The relative roles of insulin resistance and beta-cell dysfunction in the pathogenesis of impaired glucose tolerance (IGT) and type 2 diabetes are debated. First-degree relatives of individuals with type 2 diabetes are at increased risk of developing hyperglycemia. RESEARCH DESIGN AND METHODS:We evaluated th...

journal_title：Diabetes care

authors： Cnop M,Vidal J,Hull RL,Utzschneider KM,Carr DB,Schraw T,Scherer PE,Boyko EJ,Fujimoto WY,Kahn SE

更新日期：2007-03-01 00:00:00

abstract：:Unexpected plasma glucose responses to different mixed meals fed to normal and diabetic volunteers have recently been reported. We have therefore examined in normal volunteers the effect of mixing carbohydrate foods of different glycemic indices (GIs) without the addition of fat and protein. The observed GI of the mix...

journal_title：Diabetes care

authors： Wolever TM,Nuttall FQ,Lee R,Wong GS,Josse RG,Csima A,Jenkins DJ

更新日期：1985-09-01 00:00:00

abstract：OBJECTIVE:To determine whether the association between depressive symptoms and glycemic control is mediated by blood glucose monitoring (BGM). RESEARCH DESIGN AND METHODS:A total of 276 adolescents with type 1 diabetes (mean age +/- SD, 15.6 +/- 1.4 years) completed a measure of depressive symptoms. Sociodemographic a...

journal_title：Diabetes care

authors： McGrady ME,Laffel L,Drotar D,Repaske D,Hood KK

更新日期：2009-05-01 00:00:00

abstract：OBJECTIVE:To review the current knowledge about nonpharmacologic approaches in the prevention and early treatment of type 2 diabetes. RESEARCH DESIGN AND METHODS:This study reviewed the research reports dealing with nonpharmacologic interventions aimed at preventing type 2 diabetes with early lifestyle interventions. ...

journal_title：Diabetes care

authors： Tuomilehto J

更新日期：2009-11-01 00:00:00

abstract：:Our objective was to define glomerular filtration rate (GFR) and renal plasma flow (RPF) in Black Americans with non-insulin-dependent diabetes mellitus (NIDDM). This was a cross-sectional study of 71 Black NIDDM patients with diagnosed diabetes duration from 1 mo to 21 yr. Hyperglycemia was regulated and stabilized b...

journal_title：Diabetes care

authors： Lebovitz HE,Palmisano J

更新日期：1990-11-01 00:00:00

abstract：OBJECTIVE:We aimed at analyzing the frequency, clinical characteristics, and trends associated with the occurrence of diabetic ketoacidosis (DKA) at the onset of type 1 diabetes on the basis of long-term follow-up data. RESEARCH DESIGN AND METHODS:A total of 106 pediatric diabetes centers in Germany and Austria partic...

journal_title：Diabetes care

authors： Neu A,Hofer SE,Karges B,Oeverink R,Rosenbauer J,Holl RW,DPV Initiative and the German BMBF Competency Network for Diabetes Mellitus.

更新日期：2009-09-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to compare measurements of glucose obtained via iontophoretic extraction with the GlucoWatch automatic glucose biographer (Cygnus, Inc., Redwood City, CA) with capillary blood glucose values that were determined 1) in a controlled outpatient clinic setting and 2) in a home settin...

journal_title：Diabetes care

authors： Garg SK,Potts RO,Ackerman NR,Fermi SJ,Tamada JA,Chase HP

更新日期：1999-10-01 00:00:00

abstract：OBJECTIVE:To investigate the effect of parenteral insulin therapy on endogenous insulin secretion in the Diabetes Prevention Trial-Type 1 (DPT-1). RESEARCH DESIGN AND METHODS:In the parenteral insulin arm of DPT-1, subjects without diabetes at high risk of future type 1 diabetes randomized to active treatment received...

journal_title：Diabetes care

authors： Hao W,Greenbaum CJ,Krischer JP,Cuthbertson D,Marks JB,Palmer JP

更新日期：2015-05-01 00:00:00

abstract：OBJECTIVE:Glycemic control using inhaled, dry-powder insulin plus a single injection of long-acting insulin was compared with a conventional regimen in patients with type 2 diabetes, which was previously managed with at least two daily insulin injections. RESEARCH DESIGN AND METHODS:Patients were randomized to 6 month...

journal_title：Diabetes care

authors： Hollander PA,Blonde L,Rowe R,Mehta AE,Milburn JL,Hershon KS,Chiasson JL,Levin SR

更新日期：2004-10-01 00:00:00

abstract：OBJECTIVE:We sought to ascertain quality-of-life measures and utility values associated with visual acuity in type 2 diabetes. RESEARCH DESIGN AND METHODS:The Medical Outcome Study Short Form with 36 items (SF-36) was administered to 4,051 individuals with type 2 diabetes who were enrolled in the Lipids in Diabetes St...

journal_title：Diabetes care

authors： Clarke PM,Simon J,Cull CA,Holman RR

更新日期：2006-07-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to compare the University of Texas (UT) and Site, Ischemia, Neuropathy, Bacterial Infection, and Depth (SINBAD) foot ulcer scores in predicting ulcer outcome within a routine diabetes foot clinic. RESEARCH DESIGN AND METHODS:From 2006 to 2018, data were collected from all patients a...

journal_title：Diabetes care

authors： Leese GP,Soto-Pedre E,Schofield C

更新日期：2021-02-01 00:00:00

abstract：OBJECTIVE:To assess the prognostic role of ambulatory 24-h pulse pressure (PP) on various vascular events in relatively young type 2 diabetic subjects under 60 years of age. RESEARCH DESIGN AND METHODS:In this prospective study, 237 type 2 diabetic subjects without any history of vascular complications were analyzed. ...

journal_title：Diabetes care

authors： Nakano S,Konishi K,Furuya K,Uehara K,Nishizawa M,Nakagawa A,Kigoshi T,Uchida K

更新日期：2005-01-01 00:00:00

abstract：OBJECTIVE:Determine the serum levels of endogenous secretory receptor for advanced glycation end products (esRAGEs) in patients with type 2 diabetes and mild cognitive impairment (MCI) and in control patients with type 2 diabetes but no MCI, and examine the relationship of esRAGE and MCI with other clinical factors. R...

journal_title：Diabetes care

authors： Chen G,Cai L,Chen B,Liang J,Lin F,Li L,Lin L,Yao J,Wen J,Huang H

更新日期：2011-12-01 00:00:00

abstract：OBJECTIVE:We examined the joint effects of insomnia and objective short sleep duration, the combination of which is associated with higher morbidity, on diabetes risk. RESEARCH DESIGN AND METHODS:A total of 1,741 men and women randomly selected from Central Pennsylvania were studied in the sleep laboratory. Insomnia w...

journal_title：Diabetes care

authors： Vgontzas AN,Liao D,Pejovic S,Calhoun S,Karataraki M,Bixler EO

更新日期：2009-11-01 00:00:00

abstract：OBJECTIVE:To determine the prevalence of diabetes in Tohono O'odham pregnancies, and to assess the efficacy of early prenatal diabetes screening in populations with high rates of diabetes. RESEARCH DESIGN AND METHODS:All Tohono O'odham women receiving prenatal care at the Sells Service Unit who delivered a viable baby...

journal_title：Diabetes care

authors： Livingston RC,Bachman-Carter K,Frank C,Mason WB

更新日期：1993-01-01 00:00:00

abstract：OBJECTIVE:To compare platelet plasminogen activator inhibitor 1 (PAI-1) release in type II diabetic patients and healthy control subjects. RESEARCH DESIGN AND METHODS:We studied a group of 27 diabetic patients and a group of 16 nondiabetic control subjects. Whole-blood platelet aggregation, defined as a decrease in pl...

journal_title：Diabetes care

authors： Jokl R,Klein RL,Lopes-Virella MF,Colwell JA

更新日期：1995-08-01 00:00:00

abstract：OBJECTIVE:To compare A1C and fasting glucose for the diagnosis of diabetes among U.S. adults. RESEARCH DESIGN AND METHODS:This study included 6,890 adults (> or =20 years of age) from the 1999-2006 National Health and Nutrition Examination Survey without a self-reported history of diabetes who had fasted > or =9 h. A1...

journal_title：Diabetes care

authors： Carson AP,Reynolds K,Fonseca VA,Muntner P

更新日期：2010-01-01 00:00:00

abstract：OBJECTIVE:Many non-European ethnic groups have an increased risk for diabetes; however, the published literature demonstrates considerable uncertainty about the rates of diabetes complications among minority populations. The objective of this study was to determine the risks of cardiovascular complications and of morta...

journal_title：Diabetes care

authors： Shah BR,Victor JC,Chiu M,Tu JV,Anand SS,Austin PC,Manuel DG,Hux JE

更新日期：2013-09-01 00:00:00

abstract：OBJECTIVES:Obesity is a common condition in type 2 diabetic patients. Treating obesity may enhance hypoglycemic treatment and contribute to the reduction of long-term microvascular and macrovascular complications. Orlistat reduces cardiovascular risk factors in obese type 2 diabetic patients. The objectives of this stu...

journal_title：Diabetes care

authors： Lamotte M,Annemans L,Lefever A,Nechelput M,Masure J

更新日期：2002-02-01 00:00:00

abstract：OBJECTIVE:We investigated whether islet autoantibody profile, HLA-DQ genotype, and age influenced a 20-year progression to diabetes from first autoantibody positivity (autoAb+) in first-degree relatives of patients with type 1 diabetes. RESEARCH DESIGN AND METHODS:Persistently islet autoAb+ siblings and offspring (n =...

journal_title：Diabetes care

authors： Gorus FK,Balti EV,Messaaoui A,Demeester S,Van Dalem A,Costa O,Dorchy H,Mathieu C,Van Gaal L,Keymeulen B,Pipeleers DG,Weets I,Belgian Diabetes Registry.

更新日期：2017-08-01 00:00:00

abstract：OBJECTIVE:The monosaccharides resulting from the digestion of ingested carbohydrates are glucose, fructose, and galactose. Of these three monosaccharides, only ingested glucose resulted in a large increase in the plasma glucose concentration. Fructose (Metabolism 41:510-517, 1992) and galactose (Metabolism 42:1560-1567...

journal_title：Diabetes care

authors： Gannon MC,Nuttall FQ,Westphal SA,Fang S,Ercan-Fang N

更新日期：1998-10-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to assess changes in the prevalence of preexisting diabetes (diabetes antedating pregnancy) and gestational diabetes mellitus (GDM) from 1999 through 2005. RESEARCH DESIGN AND METHODS:In this retrospective study of 175,249 women aged 13-58 years with 209,287 singleton deliveries...

journal_title：Diabetes care

authors： Lawrence JM,Contreras R,Chen W,Sacks DA

更新日期：2008-05-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to assess fertility in women with type 1 diabetes and the risk of congenital malformations in their offspring. RESEARCH DESIGN AND METHODS:This was a register-based cohort study in Sweden. All 5,978 women hospitalized for type 1 diabetes at age

journal_title：Diabetes care

authors： Jonasson JM,Brismar K,Sparén P,Lambe M,Nyrén O,Ostenson CG,Ye W

更新日期：2007-09-01 00:00:00

abstract：OBJECTIVE:Women with diabetes have a high incidence and complication rate of urinary tract infections (UTIs). Our aims were to compare current treatment strategies with respect to recurrence rates in women with diabetes with those without diabetes. RESEARCH DESIGN AND METHODS:We used a Dutch registration database cont...

journal_title：Diabetes care

authors： Schneeberger C,Stolk RP,Devries JH,Schneeberger PM,Herings RM,Geerlings SE

更新日期：2008-07-01 00:00:00

abstract：OBJECTIVE:To investigate the efficacy and safety of prandial Technosphere inhaled insulin (TI), an inhaled insulin with a distinct time action profile, in insulin-naïve type 2 diabetes (T2D) inadequately controlled on oral antidiabetes agents (OADs). RESEARCH DESIGN AND METHODS:Subjects with T2D with HbA1c levels ≥7.5...

journal_title：Diabetes care

authors： Rosenstock J,Franco D,Korpachev V,Shumel B,Ma Y,Baughman R,Amin N,McGill JB,Affinity 2 Study Group.

更新日期：2015-12-01 00:00:00

abstract：:The etiology of impotence in the diabetic population has not been clearly defined. To assess this problem, 24 impotent diabetic subjects, 21 nonimpotent diabetic subjects, and 10 subjects with psychogenic impotence were compared with nocturnal monitoring of penile tumescence and rigidity, penile arterial blood flow, a...

journal_title：Diabetes care

authors： Daniels JS

更新日期：1989-07-01 00:00:00

abstract：OBJECTIVE:Hypoxia plays a major pathogenic role in diabetic nephropathy (DN). We have investigated in this study the effect of hypoxia-inducible factor 1 α subunit (HIF1A) genetic polymorphisms on the development of DN. RESEARCH DESIGN AND METHODS:In 1,165 American type 1 diabetic patients with and without DN selected...

journal_title：Diabetes care

authors： Gu HF,Zheng X,Abu Seman N,Gu T,Botusan IR,Sunkari VG,Lokman EF,Brismar K,Catrina SB

更新日期：2013-02-01 00:00:00