Depressive symptoms and glycemic control in adolescents with type 1 diabetes: mediational role of blood glucose monitoring.

Abstract:

OBJECTIVE:To determine whether the association between depressive symptoms and glycemic control is mediated by blood glucose monitoring (BGM). RESEARCH DESIGN AND METHODS:A total of 276 adolescents with type 1 diabetes (mean age +/- SD, 15.6 +/- 1.4 years) completed a measure of depressive symptoms. Sociodemographic and family characteristics were obtained from caregivers. BGM frequency and glycemic control were obtained at a clinic visit. RESULTS:Separate regression analyses revealed that depressive symptoms were associated with lower BGM frequency (B = -0.03; P = 0.04) and higher A1C (B = 0.03; P = 0.05) and that lower BGM frequency was associated with higher A1C (B = -0.39; P < 0.001). With depressive symptoms and BGM frequency included together, only BGM frequency was associated with A1C and depressive symptoms became nonsignificant (B = 0.02; P = 0.19). The Sobel test was significant (Z = 1.96; P < 0.05) and showed that 38% of the depression-A1C link can be explained by BGM. CONCLUSIONS:BGM is a mediator between depressive symptoms and glycemic control in adolescents with type 1 diabetes.

journal_name

Diabetes Care

journal_title

Diabetes care

authors

McGrady ME,Laffel L,Drotar D,Repaske D,Hood KK

doi

10.2337/dc08-2111

subject

Has Abstract

pub_date

2009-05-01 00:00:00

pages

804-6

issue

5

eissn

0149-5992

issn

1935-5548

pii

dc08-2111

journal_volume

32

pub_type

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