Abstract:
OBJECTIVE:The purpose of this study was to assess fertility in women with type 1 diabetes and the risk of congenital malformations in their offspring.
RESEARCH DESIGN AND METHODS:This was a register-based cohort study in Sweden. All 5,978 women hospitalized for type 1 diabetes at age journal_name journal_title authors doi subject pub_date pages issue eissn issn pii journal_volume pub_type
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DIABETES CARE文献大全abstract::This study describes the pharmacokinetics of three intermediate-acting insulin preparations, NPH porcine insulin, NPH human insulin (recombinant DNA), and "Depot-A" insulin, a mixture of 20% regular and 80% NPH human insulin from Eli Lilly and Company. Metabolic healthy normal weight volunteers were selected for the s...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/diacare.5.2.s43
更新日期:1982-11-01 00:00:00
abstract:OBJECTIVE:Severe hyperglycemia and hypoglycemia ("severe dysglycemia") are serious complications of type 1 diabetes (T1D). Depression has been associated with severe dysglycemia in type 2 diabetes but has not been thoroughly examined specifically in T1D. We evaluated bidirectional associations between depression and se...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/dc17-1566
更新日期:2018-03-01 00:00:00
abstract:OBJECTIVE:To evaluate racial differences and factors associated with worse glycemic control in well-functioning older individuals with type 2 diabetes. Our hypothesis was that glycemic control would be worse among black than white diabetic individuals but that this association would be explained by differences in sever...
journal_title:Diabetes care
pub_type: 杂志文章,多中心研究
doi:10.2337/diacare.26.7.1986
更新日期:2003-07-01 00:00:00
abstract::The goal of this study was to evaluate a program of resistance weight training on cardiovascular risk factors, blood glucose management, and overall strength in diabetic subjects. A randomized crossover design was performed on eight male type I (insulin-dependent) diabetic subjects (mean +/- SD age 31 +/- 3.5 yr, heig...
journal_title:Diabetes care
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.2337/diacare.13.10.1039
更新日期:1990-10-01 00:00:00
abstract:OBJECTIVE:To examine patients' views of the acceptability of and satisfaction with telephone care center support provided to improve blood glucose control in type 2 diabetes. RESEARCH DESIGN AND METHODS:The Pro-Active Call-Center Treatment Support (PACCTS) Trial randomized patients from 47 general practices in a depri...
journal_title:Diabetes care
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.2337/diacare.28.2.283
更新日期:2005-02-01 00:00:00
abstract:OBJECTIVE:Type 2 diabetes is a heterogeneous disease in which both beta-cell dysfunction and insulin resistance are pathogenetic factors. Disproportionate hyperproinsulinemia (elevated proinsulin/insulin) is another abnormality in type 2 diabetes whose mechanism is unknown. Increased demand due to obesity and/or insuli...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/diacare.22.4.609
更新日期:1999-04-01 00:00:00
abstract:OBJECTIVE:This study evaluated the ability of the Building, Relating, Assessing, and Validating Outcomes (BRAVO) risk engine to accurately project cardiovascular outcomes in three major clinical trials-BI 10773 (Empagliflozin) Cardiovascular Outcome Event Trial in Type 2 Diabetes Mellitus Patients (EMPA-REG OUTCOME), C...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/dc20-0227
更新日期:2020-07-01 00:00:00
abstract:OBJECTIVE:To characterize metabolic effects of troglitazone in type 2 diabetic, obese, and lean subjects, and examine the effects of troglitazone 2-3 weeks after discontinuation. RESEARCH DESIGN AND METHODS:Nine type 2 diabetic, nine obese, and nine lean subjects underwent baseline metabolic studies including an 8-h m...
journal_title:Diabetes care
pub_type: 临床试验,杂志文章
doi:10.2337/diacare.23.1.64
更新日期:2000-01-01 00:00:00
abstract:OBJECTIVE:We evaluated the safety and efficacy of day-and-night fully closed-loop insulin therapy using faster (Faster-CL) compared with standard insulin aspart (Standard-CL) in young adults with type 1 diabetes. RESEARCH DESIGN AND METHODS:In a double-blind, randomized, crossover trial, 20 participants with type 1 di...
journal_title:Diabetes care
pub_type: 杂志文章,随机对照试验
doi:10.2337/dc19-0895
更新日期:2020-01-01 00:00:00
abstract::Malfunction of portable continuous subcutaneous insulin infusion (CSII) systems may result in either ketoacidosis or serious hypoglycemia. To determine the types and frequencies of infusion system failure and the resulting clinical consequences, we recorded their occurrences in a 1-yr prospective study of 127 patients...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/diacare.9.4.351
更新日期:1986-07-01 00:00:00
abstract:OBJECTIVE:Serine-threonine kinase STK11 catalyzes the AMP-activated protein kinase complex. We tested the hypothesis that a gene variant in STK11 contributes to variation in insulin sensitivity and metformin efficacy. RESEARCH DESIGN AND METHODS:We studied the effects of a single nucleotide polymorphism (SNP) (rs81116...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/dc09-1750
更新日期:2010-07-01 00:00:00
abstract:OBJECTIVE:This study evaluated the feasibility, safety, and efficacy of day-and-night hybrid closed-loop insulin delivery in adolescents with type 1 diabetes under free-living conditions. RESEARCH DESIGN AND METHODS:In an open-label randomized crossover study, 12 suboptimally controlled adolescents on insulin pump the...
journal_title:Diabetes care
pub_type: 杂志文章,随机对照试验
doi:10.2337/dc16-1094
更新日期:2016-11-01 00:00:00
abstract:OBJECTIVE:To determine the incidence of insulin-dependent diabetes mellitus (IDDM) in children aged 0-14 years in Kuwait, as part of the World Health Organization Multinational Collaborative Study (DIAMOND), and to determine if the incidence rates have increased. RESEARCH DESIGN AND METHODS:All cases of IDDM diagnosed...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/diacare.18.7.923
更新日期:1995-07-01 00:00:00
abstract:OBJECTIVE:The primary outcome is to evaluate the relationship between diabetes distress and decisional conflict regarding diabetes care in patients with diabetes and two or more comorbidities. Secondary outcomes include the relationships between diabetes distress and quality of life and patient perception of chronic il...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/dc18-1256
更新日期:2019-07-01 00:00:00
abstract::OBJECTIVE- We examined the influence of a moderately elevated serum ferritin level at entry to care on the risk of gestational diabetes mellitus (GDM) and a possible mechanism (increased iron stores versus inflammation). RESEARCH DESIGN AND METHODS- In a prospective observational study with 1,456 healthy pregnant wome...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/diacare.2951077
更新日期:2006-05-01 00:00:00
abstract:OBJECTIVE:Preclinical data suggest that linagliptin, a dipeptidyl peptidase-4 inhibitor, may lower urinary albumin excretion. The ability of linagliptin to lower albuminuria on top of renin-angiotensin-aldosterone system (RAAS) inhibition in humans was analyzed by pooling data from four similarly designed, 24-week, ran...
journal_title:Diabetes care
pub_type: 杂志文章,随机对照试验
doi:10.2337/dc13-0323
更新日期:2013-11-01 00:00:00
abstract:OBJECTIVE:Diabetes is the leading cause of nontraumatic lower-limb amputations in the U.S., but no research has prospectively examined associations between limb-specific measurements and amputation risk among patients without foot ulcer. We investigated amputation risk by limb in relation to the same limb- and person-l...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/dc17-2210
更新日期:2018-04-01 00:00:00
abstract:OBJECTIVE:Therapies with metformin, sulfonylureas, or insulin improve glycemic control in the short term but do not prevent progressive islet beta-cell failure or long-term deterioration in glycemia. Our goal was to evaluate, in patients recently diagnosed with type 2 diabetes (<3 years), the long-term efficacy of mono...
journal_title:Diabetes care
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.2337/diacare.25.10.1737
更新日期:2002-10-01 00:00:00
abstract:OBJECTIVE:It has proved difficult to separate the role of the diabetic state as distinct from its complications in causing the elevation in erythrocyte sodium-lithium (Na-Li) countertransport activity that has been observed in diabetes. The present study sought to isolate the impact of diabetes on the countertransporte...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/diacare.19.1.32
更新日期:1996-01-01 00:00:00
abstract:OBJECTIVE:To examine medical and mental health care expenditures for large numbers of individuals with diabetes enrolled in employment-sponsored insurance plans. RESEARCH DESIGN AND METHODS:Health insurance billing data for approximately 1.3 million individuals enrolled in health insurance plans sponsored by 862 large...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/diacare.25.11.1964
更新日期:2002-11-01 00:00:00
abstract:OBJECTIVE:The decline in C-peptide in the 5 years after diagnosis of type 1 diabetes has been well studied, but little is known about the longer-term trajectory. We aimed to examine the association between log-transformed C-peptide levels and the duration of diabetes up to 40 years after diagnosis. RESEARCH DESIGN AND...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/dc18-0465
更新日期:2018-07-01 00:00:00
abstract:OBJECTIVE:Dietary recommendations are focused mainly on relative dietary fat and carbohydrate content in relation to diabetes risk. Meanwhile, high-protein diets may contribute to disturbance of glucose metabolism, but evidence from prospective studies is scarce. We examined the association among dietary total, vegetab...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/dc09-1321
更新日期:2010-01-01 00:00:00
abstract:OBJECTIVE:To determine contributions of trunk and extremity adiposity to cardiometabolic risk factors (blood pressure, fasting blood glucose, HDL cholesterol, and triglycerides) among white and African American adults. RESEARCH DESIGN AND METHODS:The sample consisted of 1,129 white women, 779 African American women, 1...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/dc10-2019
更新日期:2011-06-01 00:00:00
abstract:OBJECTIVE:The purpose of this study was to evaluate the effects of a combination weight loss program using intermittent low-calorie diets, energy-controlled meal replacement products, and sibutramine on weight loss, diabetes control, and cardiovascular risk factors in overweight or obese subjects with type 2 diabetes. ...
journal_title:Diabetes care
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.2337/diacare.26.9.2505
更新日期:2003-09-01 00:00:00
abstract:OBJECTIVE:To characterize renal impairment associated with diabetes in older adults by serum markers of glomerular filtration rate and microalbuminuria tests. RESEARCH DESIGN AND METHODS:The study population consisted of 187 diabetic and 1,073 nondiabetic subjects (age range 64-100 years) participating in a cross-sect...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/diacare.27.11.2648
更新日期:2004-11-01 00:00:00
abstract:OBJECTIVE:To determine if nephropathy in NIDDM is associated with cellular markers for hypertension. RESEARCH DESIGN AND METHODS:We compared 11 patients with clinical diabetic nephropathy with 15 control subjects with no diabetic nephropathy. The patients were white and had had NIDDM for > or = 9 yr and serum creatini...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/diacare.16.5.815
更新日期:1993-05-01 00:00:00
abstract:OBJECTIVE:The specific aims of the present study were to report on the level of personal beliefs and social and environmental barriers across different regimen areas and patient subgroups and on the relationship of personal models and perceived barriers to the level of self-management. RESEARCH DESIGN AND METHODS:This...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/diacare.20.4.556
更新日期:1997-04-01 00:00:00
abstract::Thirty-eight non-insulin-dependent diabetic patients within 130% of desirable body weight were given a 100-g oral glucose tolerance test (OGTT) at diagnosis and after at least 1 mo of dietary treatment with energy and carbohydrate restriction. Thirteen "responders" showed an improvement in fasting blood glucose, gluco...
journal_title:Diabetes care
pub_type: 临床试验,杂志文章
doi:
更新日期:1984-05-01 00:00:00
abstract:OBJECTIVE:Low plasma testosterone levels are associated with hyperinsulinemia and glucose intolerance in men. However, it is unclear whether these abnormalities are related to the concomitant alteration in regional adipose tissue (AT) accumulation associated with reduced androgen levels. RESEARCH DESIGN AND METHODS:We...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/diacare.18.3.292
更新日期:1995-03-01 00:00:00
abstract:OBJECTIVE:To examine the acute glucose-lowering effects of aerobic exercise in children and adolescents with type 1 diabetes. RESEARCH DESIGN AND METHODS:Fifty children and adolescents with type 1 diabetes (ages 10 to <18 years) were studied during exercise. The 75-min exercise session consisted of four 15-min periods...
journal_title:Diabetes care
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.2337/diacare.29.1.20
更新日期:2006-01-01 00:00:00