Rapid progression of albumin excretion is an independent predictor of cardiovascular mortality in patients with type 2 diabetes and microalbuminuria.

abstract：OBJECTIVE:To characterize renal impairment associated with diabetes in older adults by serum markers of glomerular filtration rate and microalbuminuria tests. RESEARCH DESIGN AND METHODS:The study population consisted of 187 diabetic and 1,073 nondiabetic subjects (age range 64-100 years) participating in a cross-sect...

journal_title：Diabetes care

authors： Wasén E,Isoaho R,Mattila K,Vahlberg T,Kivelä SL,Irjala K

更新日期：2004-11-01 00:00:00

abstract：OBJECTIVE:To characterize the insulin sensitivity of overweight and obese 5- to 10-year-old (Tanner stage 1-3) African-American children screened for participation in a diabetes prevention study and to identify the association of insulin sensitivity with obesity, hyperlipidemia, and hypertension. RESEARCH DESIGN AND M...

journal_title：Diabetes care

authors： Young-Hyman D,Schlundt DG,Herman L,De Luca F,Counts D

更新日期：2001-08-01 00:00:00

abstract：OBJECTIVE:To investigate the effect of treatment with the glucagon-like peptide 1 receptor agonist exenatide on weight loss and metabolic parameters in obese nondiabetic women. RESEARCH DESIGN AND METHODS:Forty-one obese women (aged 48 ± 11 years and BMI 33.1 ± 4.1 kg/m(2)) participated in a 35-week randomized, double...

journal_title：Diabetes care

authors： Dushay J,Gao C,Gopalakrishnan GS,Crawley M,Mitten EK,Wilker E,Mullington J,Maratos-Flier E

更新日期：2012-01-01 00:00:00

abstract：OBJECTIVE:To examine the contribution of nerve-axon reflex-related vasodilation to total acetylcholine-induced vasodilation in the skin of normal and diabetic subjects. RESEARCH DESIGN AND METHODS:The skin microcirculation was evaluated at the forearm level in 69 healthy subjects and 42 nonneuropathic diabetic patient...

journal_title：Diabetes care

authors： Hamdy O,Abou-Elenin K,LoGerfo FW,Horton ES,Veves A

更新日期：2001-02-01 00:00:00

abstract：OBJECTIVE:The International Diabetes Mellitus Practice Study is a 5-year survey documenting changes in diabetes treatment practice in developing regions. RESEARCH DESIGN AND METHODS:Logistic regression analysis was used to identify factors for achieving A1C <7% in 11,799 patients (1,898 type 1 diabetic and 9,901 type ...

journal_title：Diabetes care

authors： Chan JC,Gagliardino JJ,Baik SH,Chantelot JM,Ferreira SR,Hancu N,Ilkova H,Ramachandran A,Aschner P,IDMPS Investigators.

更新日期：2009-02-01 00:00:00

abstract：OBJECTIVE:To compare a simple meal plan emphasizing healthy food choices with a traditional exchange-based meal plan in reducing HbA(1c) levels in urban African Americans with type 2 diabetes. RESEARCH DESIGN AND METHODS:A total of 648 patients with type 2 diabetes were randomized to receive instruction in either a he...

journal_title：Diabetes care

authors： Ziemer DC,Berkowitz KJ,Panayioto RM,El-Kebbi IM,Musey VC,Anderson LA,Wanko NS,Fowke ML,Brazier CW,Dunbar VG,Slocum W,Bacha GM,Gallina DL,Cook CB,Phillips LS

更新日期：2003-06-01 00:00:00

abstract：OBJECTIVE:To evaluate the effectiveness of a telephone-delivered behavioral weight loss and physical activity intervention targeting Australian primary care patients with type 2 diabetes. RESEARCH DESIGN AND METHODS:Pragmatic randomized controlled trial of telephone counseling (n = 151) versus usual care (n = 151). Re...

journal_title：Diabetes care

authors： Eakin EG,Winkler EA,Dunstan DW,Healy GN,Owen N,Marshall AM,Graves N,Reeves MM

更新日期：2014-08-01 00:00:00

abstract：OBJECTIVE:To examine the safety and efficacy of dapagliflozin, a sodium-glucose cotransporter-2 inhibitor, added on to pioglitazone in type 2 diabetes inadequately controlled on pioglitazone. RESEARCH DESIGN AND METHODS:Treatment-naive patients or those receiving metformin, sulfonylurea, or thiazolidinedione entered a...

journal_title：Diabetes care

authors： Rosenstock J,Vico M,Wei L,Salsali A,List JF

更新日期：2012-07-01 00:00:00

abstract：OBJECTIVE:We sought to ascertain quality-of-life measures and utility values associated with visual acuity in type 2 diabetes. RESEARCH DESIGN AND METHODS:The Medical Outcome Study Short Form with 36 items (SF-36) was administered to 4,051 individuals with type 2 diabetes who were enrolled in the Lipids in Diabetes St...

journal_title：Diabetes care

authors： Clarke PM,Simon J,Cull CA,Holman RR

更新日期：2006-07-01 00:00:00

abstract：OBJECTIVE:The objective of this study was to examine the associations between the severity of hepatic steatosis and dyslipidemia in type 2 diabetes, including circulating apolipoprotein B100 (apoB) concentrations and lipoprotein particle size and numbers. RESEARCH DESIGN AND METHODS:Computed tomography imaging was use...

journal_title：Diabetes care

authors： Toledo FG,Sniderman AD,Kelley DE

更新日期：2006-08-01 00:00:00

abstract：OBJECTIVE:We examined the associations of symptoms of sleep-disordered breathing (SDB), which was defined as loud snoring, stopping breathing for a while during sleep, and daytime sleepiness, and insomnia with glucose metabolism and incident type 2 diabetes in older adults. RESEARCH DESIGN AND METHODS:Between 1989 and...

journal_title：Diabetes care

authors： Strand LB,Carnethon M,Biggs ML,Djoussé L,Kaplan RC,Siscovick DS,Robbins JA,Redline S,Patel SR,Janszky I,Mukamal KJ

更新日期：2015-11-01 00:00:00

abstract：:Coronary artery disease (CAD) accounts for a large fraction of the morbidity, mortality, and cost of diabetes. Recognizing this, nearly 10 years ago the American Diabetes Association published a consensus recommendation that clinicians consider a risk factor-guided screening approach to early diagnosis of CAD in both ...

journal_title：Diabetes care

authors： Bax JJ,Young LH,Frye RL,Bonow RO,Steinberg HO,Barrett EJ,ADA.

更新日期：2007-10-01 00:00:00

abstract：OBJECTIVE:We aimed at analyzing the frequency, clinical characteristics, and trends associated with the occurrence of diabetic ketoacidosis (DKA) at the onset of type 1 diabetes on the basis of long-term follow-up data. RESEARCH DESIGN AND METHODS:A total of 106 pediatric diabetes centers in Germany and Austria partic...

journal_title：Diabetes care

authors： Neu A,Hofer SE,Karges B,Oeverink R,Rosenbauer J,Holl RW,DPV Initiative and the German BMBF Competency Network for Diabetes Mellitus.

更新日期：2009-09-01 00:00:00

abstract：OBJECTIVE:To assess the impact of hyperglycemia in different age-groups of patients with acute myocardial infarction (AMI). RESEARCH DESIGN AND METHODS:A total of 2,027 patients with AMI were categorized into one of five age-groups: <50 years (n = 301), ≥50 and <60 (n = 477), ≥60 and <70 (n = 545), ≥70 and <80 (n = 49...

journal_title：Diabetes care

authors： Nicolau JC,Serrano CV Jr,Giraldez RR,Baracioli LM,Moreira HG,Lima F,Franken M,Kalil R,Ramires JA,Giugliano RP

更新日期：2012-01-01 00:00:00

abstract：OBJECTIVE:Inflammatory activity is increased in type 1 diabetes and may predispose to vascular disease. Its origin is not clear. We therefore investigated determinants of inflammation in type 1 diabetes. RESEARCH DESIGN AND METHODS:We performed a nested case-control study from the EURODIAB Prospective Complications St...

journal_title：Diabetes care

authors： Schram MT,Chaturvedi N,Schalkwijk C,Giorgino F,Ebeling P,Fuller JH,Stehouwer CD,EURODIAB Prospective Complications Study.

更新日期：2003-07-01 00:00:00

abstract：:The economic burden of diabetes in the U.S. is now more than 90 billion dollars per year (113-115). In the diabetes community, there is a feeling that aggressive measures to detect diabetes in earlier stages may be warranted. Regardless of whether evidence is convincing that there are benefits from early detection of ...

journal_title：Diabetes care

authors： Engelgau MM,Aubert RE,Thompson TJ,Herman WH

更新日期：1995-12-01 00:00:00

abstract：OBJECTIVE:To determine whether women with pregestational diabetes obtained long-term benefits from an intensive diabetes management program during pregnancy. RESEARCH DESIGN AND METHODS:Women with pregestational diabetes who had attended an intensive diabetes management program in pregnancy between 1991 and 1999 were ...

journal_title：Diabetes care

authors： Feig DS,Cleave B,Tomlinson G

更新日期：2006-03-01 00:00:00

abstract：OBJECTIVE:We prospectively investigated in hypertensive patients with type 2 diabetes if bedtime treatment with ≥1 hypertension medications exerts better blood pressure control and cardiovascular risk reduction than conventional therapy, in which all medications are ingested in the morning. RESEARCH DESIGN AND METHODS...

journal_title：Diabetes care

authors： Hermida RC,Ayala DE,Mojón A,Fernández JR

更新日期：2011-06-01 00:00:00

abstract：:NIDDM in Pima Indians is characterized by obesity, abnormal insulin secretion, insulin resistance, and excess hepatic glucose output. Cross-sectional studies, and, as yet incomplete longitudinal studies of nondiabetic and diabetic Pima Indians suggest that the natural history of the disease begins with insulin resista...

journal_title：Diabetes care

authors： Bogardus C

更新日期：1993-01-01 00:00:00

abstract：OBJECTIVES:Obesity is a common condition in type 2 diabetic patients. Treating obesity may enhance hypoglycemic treatment and contribute to the reduction of long-term microvascular and macrovascular complications. Orlistat reduces cardiovascular risk factors in obese type 2 diabetic patients. The objectives of this stu...

journal_title：Diabetes care

authors： Lamotte M,Annemans L,Lefever A,Nechelput M,Masure J

更新日期：2002-02-01 00:00:00

abstract：:Urinary C-peptide (UCP) is a noninvasive measure of integrated insulin production, and the usefulness of 24-h collections has been previously reported. Only small numbers of subjects have been studied using shorter urine collections. To see how well 4-h urine collections for C-peptide (UCP) correlate with serum immuno...

journal_title：Diabetes care

authors： Hoogwerf BJ,Barbosa JJ,Bantle JP,Laine D,Goetz FC

更新日期：1983-09-01 00:00:00

abstract：OBJECTIVE:To examine glycemic control for the prevention of retinopathy in early diagnosed Japanese NIDDM patients. RESEARCH DESIGN AND METHODS:There were 137 patients with NIDDM but without retinopathy who first visited our facility from 1983-1985. Their age at diagnosis ranged from 30-65 years, with a disease durati...

journal_title：Diabetes care

authors： Nakagami T,Kawahara R,Hori S,Omori Y

更新日期：1997-04-01 00:00:00

abstract：:Cyclosporin and other immunosuppressive agents have been proposed as a preventive treatment against the development of insulin-dependent diabetes mellitus (IDDM) in relatives at increased risk for the disease, based on the understanding that its etiology is an ongoing process of autoimmune beta-cell destruction. We us...

journal_title：Diabetes care

authors： Lipton R,LaPorte RE,Becker DJ,Dorman JS,Orchard TJ,Atchison J,Drash AL

更新日期：1990-07-01 00:00:00

abstract：:Fifty-one insulin-dependent diabetic patients, 26 children and 25 adults, participated in an open uncontrolled study of the safety and efficacy of human insulin (Novo). The patients, who had previously been treated exclusively with porcine insulin, were followed in two outpatient clinics during a 3-mo study period. Du...

journal_title：Diabetes care

authors： Lyngsøe J,Vestermark S

更新日期：1983-03-01 00:00:00

abstract：OBJECTIVE:Previous studies demonstrate that the metabolic syndrome is associated with distal symmetric polyneuropathy (DSP). We aimed to determine the magnitude of this effect and the precise components involved. RESEARCH DESIGN AND METHODS:We determined the symptomatic DSP prevalence in the Health, Aging, and Body Co...

journal_title：Diabetes care

authors： Callaghan BC,Xia R,Banerjee M,de Rekeneire N,Harris TB,Newman AB,Satterfield S,Schwartz AV,Vinik AI,Feldman EL,Strotmeyer ES,Health ABC Study.

更新日期：2016-05-01 00:00:00

abstract：OBJECTIVE:To investigate the metabolic effects of metformin, as compared with placebo, in type 2 diabetic patients intensively treated with insulin. RESEARCH DESIGN AND METHODS:Metformin improves glycemic control in poorly controlled type 2 diabetic patients. Its effect in type 2 diabetic patients who are intensively ...

journal_title：Diabetes care

authors： Wulffelé MG,Kooy A,Lehert P,Bets D,Ogterop JC,Borger van der Burg B,Donker AJ,Stehouwer CD

更新日期：2002-12-01 00:00:00

abstract：OBJECTIVE:Both food insecurity (limited food access owing to cost) and living in areas with low physical access to nutritious foods are public health concerns, but their relative contribution to diabetes management is poorly understood. RESEARCH DESIGN AND METHODS:This was a prospective cohort study. A random sample o...

journal_title：Diabetes care

authors： Berkowitz SA,Karter AJ,Corbie-Smith G,Seligman HK,Ackroyd SA,Barnard LS,Atlas SJ,Wexler DJ

更新日期：2018-06-01 00:00:00

abstract：OBJECTIVE:To compare A1C and fasting glucose for the diagnosis of diabetes among U.S. adults. RESEARCH DESIGN AND METHODS:This study included 6,890 adults (> or =20 years of age) from the 1999-2006 National Health and Nutrition Examination Survey without a self-reported history of diabetes who had fasted > or =9 h. A1...

journal_title：Diabetes care

authors： Carson AP,Reynolds K,Fonseca VA,Muntner P

更新日期：2010-01-01 00:00:00

abstract：OBJECTIVE:Determine the serum levels of endogenous secretory receptor for advanced glycation end products (esRAGEs) in patients with type 2 diabetes and mild cognitive impairment (MCI) and in control patients with type 2 diabetes but no MCI, and examine the relationship of esRAGE and MCI with other clinical factors. R...

journal_title：Diabetes care

authors： Chen G,Cai L,Chen B,Liang J,Lin F,Li L,Lin L,Yao J,Wen J,Huang H

更新日期：2011-12-01 00:00:00

abstract：OBJECTIVE:Abnormally elevated proinsulin secretion has been reported in type 2 and early type 1 diabetes when significant C-peptide is present. We questioned whether individuals with long-standing type 1 diabetes and low or absent C-peptide secretory capacity retained the ability to make proinsulin. RESEARCH DESIGN AN...

journal_title：Diabetes care

authors： Sims EK,Bahnson HT,Nyalwidhe J,Haataja L,Davis AK,Speake C,DiMeglio LA,Blum J,Morris MA,Mirmira RG,Nadler J,Mastracci TL,Marcovina S,Qian WJ,Yi L,Swensen AC,Yip-Schneider M,Schmidt CM,Considine RV,Arvan P,Greenbau

更新日期：2019-02-01 00:00:00