Insulin resistance in the pathogenesis of NIDDM in Pima Indians.

abstract：OBJECTIVE:The intraoral tactile sensitivity (ITS) of diabetic and nondiabetic subjects was compared. The effects of age, ethnicity, sex, and intraoral site were considered. RESEARCH DESIGN AND METHODS:The sample comprised 589 participants of the Oral Health: San Antonio Longitudinal Study of Aging. A total of 107 subj...

journal_title：Diabetes care

authors： Shinkai RS,Hatch JP,Cornell JE,Yeh CK

更新日期：2004-04-01 00:00:00

abstract：OBJECTIVE:To determine the effects of a Dietary Approaches to Stop Hypertension (DASH) eating plan on metabolic risks in patients with the metabolic syndrome. RESEARCH DESIGN AND METHODS:This was a randomized controlled outpatient trial conducted on 116 patients with the metabolic syndrome. Three diets were prescribed...

journal_title：Diabetes care

authors： Azadbakht L,Mirmiran P,Esmaillzadeh A,Azizi T,Azizi F

更新日期：2005-12-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to compare the prevalence of both impaired fasting glucose (IFG) and diabetes between hepatitis C virus (HCV)-infected patients and patients with other liver diseases but anti-HCV-, taking into account the degree of liver damage. RESEARCH DESIGN AND METHODS:A total of 642 consecutiv...

journal_title：Diabetes care

authors： Lecube A,Hernández C,Genescà J,Esteban JI,Jardí R,Simó R

更新日期：2004-05-01 00:00:00

abstract：OBJECTIVE:To examine the effect of pioglitazone on myocardial insulin sensitivity and left ventricular (LV) function in patients with type 2 diabetes (T2D). RESEARCH DESIGN AND METHODS:Twelve subjects with T2D and 12 with normal glucose tolerance received a euglycemic insulin clamp. Myocardial glucose uptake (MGU) and...

journal_title：Diabetes care

authors： Clarke GD,Solis-Herrera C,Molina-Wilkins M,Martinez S,Merovci A,Cersosimo E,Chilton RJ,Iozzo P,Gastaldelli A,Abdul-Ghani M,DeFronzo RA

更新日期：2017-11-01 00:00:00

abstract：:Neutral regular human insulin (Novo) (derived from porcine insulin) and porcine insulin were administered by subcutaneous (s.c.) injection into the anterior abdominal wall in two different groups of six normal male subjects. The insulin dosage was 0.075 IU/kg body wt; diluting medium was used to obtain control values....

journal_title：Diabetes care

authors： Owens DR,Jones MK,Birtwell AJ,Jones IR,Hayes TM,Heding LG

更新日期：1983-03-01 00:00:00

abstract：OBJECTIVE:Strict glycemic control in people with insulin-dependent diabetes mellitus (IDDM) reduces the risk of microvascular complications, but improvements in control are also associated with weight gain. Fears about the mortality risks of obesity may limit the acceptability of tight control. Therefore, we examined m...

journal_title：Diabetes care

authors： Chaturvedi N,Stevens LK,Fuller JH

更新日期：1995-06-01 00:00:00

abstract：OBJECTIVE:Ethnic differences in type 2 diabetes risk between South Asians and white Europeans originate before adult life and are not fully explained by higher adiposity levels in South Asians. Although metabolic sensitivity to adiposity may differ between ethnic groups, this has been little studied in childhood. We ha...

journal_title：Diabetes care

authors： Nightingale CM,Rudnicka AR,Owen CG,Wells JC,Sattar N,Cook DG,Whincup PH

更新日期：2013-06-01 00:00:00

abstract：OBJECTIVE:Improved appetite control, possibly mediated by exaggerated gut peptide responses to eating, may contribute to weight loss after Roux-en-Y gastric bypass (RYGB). This study compared brain responses to food ingestion between post-RYGB (RYGB), normal weight (NW), and obese (Ob) unoperated subjects and explored ...

journal_title：Diabetes care

authors： Hunt KF,Dunn JT,le Roux CW,Reed LJ,Marsden PK,Patel AG,Amiel SA

更新日期：2016-10-01 00:00:00

abstract：OBJECTIVE:To evaluate the temporal patterns of cardiometabolic multimorbidity (CM) and depression in White Caucasians (WCs) and African Americans (AAs) with early-onset type 2 diabetes and their impact on long-term atherosclerotic cardiovascular disease (ASCVD). RESEARCH DESIGN AND METHODS:From U.S. electronic medical...

journal_title：Diabetes care

authors： Dibato JE,Montvida O,Zaccardi F,Sargeant JA,Davies MJ,Khunti K,Paul SK

更新日期：2021-01-01 00:00:00

abstract：OBJECTIVE:The aim was to explore relationships between work-related factors, work-related diabetes distress (WRDD), diabetes distress (measured by Problem Areas in Diabetes [PAID]-5 scale), intentional hyperglycemia at work (IHW), and glycemic control. RESEARCH DESIGN AND METHODS:A cross-sectional survey was conducted...

journal_title：Diabetes care

authors： Hansen UM,Skinner T,Olesen K,Willaing I

更新日期：2019-05-01 00:00:00

abstract：OBJECTIVE:The primary outcome is to evaluate the relationship between diabetes distress and decisional conflict regarding diabetes care in patients with diabetes and two or more comorbidities. Secondary outcomes include the relationships between diabetes distress and quality of life and patient perception of chronic il...

journal_title：Diabetes care

authors： Bruno BA,Choi D,Thorpe KE,Yu CH

更新日期：2019-07-01 00:00:00

abstract：OBJECTIVE:Impaired awareness of hypoglycemia (IAH) and recurrent severe hypoglycemia (RSH) remain problematic for people with type 1 diabetes (T1D), despite major therapeutic advances. We explored beliefs around hypo- and hyperglycemia in adults with T1D with, and without, IAH and RSH. RESEARCH DESIGN AND METHODS:A cr...

journal_title：Diabetes care

authors： Cook AJ,DuBose SN,Foster N,Smith EL,Wu M,Margiotta G,Rickels MR,Speight J,de Zoysa N,Amiel SA

更新日期：2019-10-01 00:00:00

abstract：OBJECTIVE:The Diabetes Control and Complications Trial (DCCT) demonstrated the powerful impact of glycemic control on the early manifestations of microvascular complications. Contemporary prospective data on the evolution of macrovascular and late microvascular complications of type 1 diabetes are limited. The Epidemio...

journal_title：Diabetes care

authors：

更新日期：1999-01-01 00:00:00

abstract：OBJECTIVE:To evaluate effects of vildagliptin and metformin on blood pressure (BP) and heart rate (HR) responses to intraduodenal (ID) glucose in diet-controlled type 2 diabetes. RESEARCH DESIGN AND METHODS:Study A compared vildagliptin (50 mg) and placebo, given 60 min before a 120-min ID glucose infusion at 2 or 4 k...

journal_title：Diabetes care

authors： Wu T,Trahair LG,Little TJ,Bound MJ,Zhang X,Wu H,Sun Z,Horowitz M,Rayner CK,Jones KL

更新日期：2017-05-01 00:00:00

abstract：:Adjustment algorithms for conventional insulin therapy must be tested for safety and efficacy before clinical implementation. We did this by computer simulation. Accordingly, a computer simulator of human intermediary metabolism created 10 randomly chosen diabetic subjects for study. All were well defined with respect...

journal_title：Diabetes care

authors： Albisser AM,Sozzi S,Strack TR

更新日期：1990-04-01 00:00:00

abstract：:Coronary artery disease (CAD) accounts for a large fraction of the morbidity, mortality, and cost of diabetes. Recognizing this, nearly 10 years ago the American Diabetes Association published a consensus recommendation that clinicians consider a risk factor-guided screening approach to early diagnosis of CAD in both ...

journal_title：Diabetes care

authors： Bax JJ,Young LH,Frye RL,Bonow RO,Steinberg HO,Barrett EJ,ADA.

更新日期：2007-10-01 00:00:00

abstract：OBJECTIVE:To examine medical and mental health care expenditures for large numbers of individuals with diabetes enrolled in employment-sponsored insurance plans. RESEARCH DESIGN AND METHODS:Health insurance billing data for approximately 1.3 million individuals enrolled in health insurance plans sponsored by 862 large...

journal_title：Diabetes care

authors： Peele PB,Lave JR,Songer TJ

更新日期：2002-11-01 00:00:00

abstract：:The consensus algorithm for the medical management of type 2 diabetes was published in August 2006 with the expectation that it would be updated, based on the availability of new interventions and new evidence to establish their clinical role. The authors continue to endorse the principles used to develop the algorith...

journal_title：Diabetes care

authors： Nathan DM,Buse JB,Davidson MB,Ferrannini E,Holman RR,Sherwin R,Zinman B,American Diabetes Association.,European Association for Study of Diabetes.

更新日期：2009-01-01 00:00:00

abstract：:OBJECTIVE The American Diabetes Association advocates insulin regimens for youth with type 1 diabetes that involve adjusting insulin dose based on carbohydrate intake and blood glucose level. Implementing these regimens requires knowledge about carbohydrate content of foods and subsequent calculations of insulin dose,...

journal_title：Diabetes care

authors： Koontz MB,Cuttler L,Palmert MR,O'Riordan M,Borawski EA,McConnell J,Kern EO

更新日期：2010-03-01 00:00:00

abstract：OBJECTIVE:Dyslipidemia contributes to the progression of microvascular disease in diabetes. However, different lipid variables may be important at different stages of nephropathy. This study examines the pattern of dyslipidemia associated with the progression of nephropathy in patients with type 1 diabetes. RESEARCH D...

journal_title：Diabetes care

authors： Thomas MC,Rosengård-Bärlund M,Mills V,Rönnback M,Thomas S,Forsblom C,Cooper ME,Taskinen MR,Viberti G,Groop PH

更新日期：2006-02-01 00:00:00

abstract：:Neuropathic foot ulceration is a major medical and economic problem among diabetic patients, and the traditional treatment involves bed rest with complete freedom from weight-bearing. We have investigated the use of walking plaster casts in the management of seven diabetic patients with long-standing, chronic plantar ...

journal_title：Diabetes care

authors： Boulton AJ,Bowker JH,Gadia M,Lemerman R,Caswell K,Skyler JS,Sosenko JM

更新日期：1986-03-01 00:00:00

abstract：OBJECTIVE:To estimate the prevalence of known diabetes in a Swedish county (Skaraborg) and to evaluate capture-recapture methods for validation of the diabetes prevalence. RESEARCH DESIGN AND METHODS:Four sources were used to find known diabetic patients: 1) the Skaraborg Diabetes Registry (SDR), a case-finding invent...

journal_title：Diabetes care

authors： Berger B,Stenström G,Chang YF,Sundkvist G

更新日期：1998-04-01 00:00:00

abstract：OBJECTIVE:To estimate incidence rates of diabetes and associated risk factors among participants of the Strong Heart Study. RESEARCH DESIGN AND METHODS:Of the 4,549 Strong Heart Study participants examined at baseline, 3,638 returned for a similar examination after an average of 4 years. The 1985 World Health Organiza...

journal_title：Diabetes care

authors： Lee ET,Welty TK,Cowan LD,Wang W,Rhoades DA,Devereux R,Go O,Fabsitz R,Howard BV

更新日期：2002-01-01 00:00:00

abstract：OBJECTIVE:Continuous glucose monitoring (CGM) reduces HbA1c and time spent in hypoglycemia in people with type 1 diabetes (T1D) treated with multiple daily insulin injections (MDI) when evaluated over shorter time periods. It is unclear to what extent CGM improves and helps to maintain glucose control, treatment satisf...

journal_title：Diabetes care

authors： Lind M,Ólafsdóttir AF,Hirsch IB,Bolinder J,Dahlqvist S,Pivodic A,Hellman J,Wijkman M,Schwarcz E,Albrektsson H,Heise T,Polonsky W

更新日期：2021-01-01 00:00:00

abstract：OBJECTIVE:We sought to test the hypothesis that a fixed-dose combination of trandolapril/verapamil-SR (T/V) is superior to a fixed-dose combination of losartan/hydrochlorothiazide (L/H) on glucose tolerance in hypertensive patients with impaired glucose tolerance (IGT). RESEARCH DESIGN AND METHODS:A prospective, rando...

journal_title：Diabetes care

authors： Bakris G,Molitch M,Hewkin A,Kipnes M,Sarafidis P,Fakouhi K,Bacher P,Sowers J,STAR Investigators.

更新日期：2006-12-01 00:00:00

abstract：OBJECTIVE:To determine the effect of metformin on the acute metabolic response to submaximal exercise, the effect of exercise on plasma metformin concentrations, and the interaction between metformin and exercise on the subsequent response to a standardized meal. RESEARCH DESIGN AND METHODS:Ten participants with type ...

journal_title：Diabetes care

authors： Boulé NG,Robert C,Bell GJ,Johnson ST,Bell RC,Lewanczuk RZ,Gabr RQ,Brocks DR

更新日期：2011-07-01 00:00:00

abstract：OBJECTIVE:Increased Hb and ferritin have been associated with gestational diabetes mellitus (GDM). This study was performed to determine whether the prevalence of GDM is influenced by iron deficiency anemia. RESEARCH DESIGN AND METHODS:In a retrospective case-control study, 242 women with iron deficiency anemia (Hb<10...

journal_title：Diabetes care

authors： Lao TT,Ho LF

更新日期：2004-03-01 00:00:00

abstract：OBJECTIVE:To verify what information from oral glucose tolerance tests (OGTTs) independently predicts mortality. RESEARCH DESIGN AND METHODS:A total of 1,401 initially nondiabetic participants from the Baltimore Longitudinal Study of Aging aged 17-95 years underwent one or more OGTTs (median 2, range 1-8), with insuli...

journal_title：Diabetes care

authors： Metter EJ,Windham BG,Maggio M,Simonsick EM,Ling SM,Egan JM,Ferrucci L

更新日期：2008-05-01 00:00:00

abstract：OBJECTIVE:Growth deferentiation factor-15 (GDF-15) is involved in inflammation and apoptosis. Expression is induced in the heart in response to ischemia and in atherosclerotic plaques. The aim of this study was to investigate GDF-15 levels in relation to all-cause mortality, cardiovascular mortality and morbidity, decl...

journal_title：Diabetes care

authors： Lajer M,Jorsal A,Tarnow L,Parving HH,Rossing P

更新日期：2010-07-01 00:00:00

abstract：OBJECTIVE:To determine the frequency of IDDM risk-associated HLA-DQ beta alleles in New Zealanders with IDDM and nondiabetic control subjects, and to examine these as susceptibility markers in relation to IDDM incidence. RESEARCH DESIGN AND METHODS:HLA-DQ beta typing was conducted in 55 juvenile-onset IDDM subjects di...

journal_title：Diabetes care

authors： Forbes LV,Brown LJ,Scott RS

更新日期：1993-08-01 00:00:00