Mortality and morbidity associated with body weight in people with IDDM. The WHO Multinational Study of Vascular Disease in Diabetes.

abstract：OBJECTIVE:The decline in C-peptide in the 5 years after diagnosis of type 1 diabetes has been well studied, but little is known about the longer-term trajectory. We aimed to examine the association between log-transformed C-peptide levels and the duration of diabetes up to 40 years after diagnosis. RESEARCH DESIGN AND...

journal_title：Diabetes care

authors： Shields BM,McDonald TJ,Oram R,Hill A,Hudson M,Leete P,Pearson ER,Richardson SJ,Morgan NG,Hattersley AT,TIGI Consortium.

更新日期：2018-07-01 00:00:00

abstract：:Metformin is and has been considered as first-line therapy for type 2 diabetes for over a quarter of a century. Like other biguanides, metformin can cause a lactic acidosis that is exceptionally rare but fatal. The likelihood of metformin-associated lactic acidosis is substantially higher in patients with kidney impai...

journal_title：Diabetes care

authors： Bakris GL,Molitch ME

更新日期：2016-07-01 00:00:00

abstract：OBJECTIVE:To evaluate the impact of systematic patient evaluation and patient and provider feedback on the processes and intermediate outcomes of diabetes care in Independent Practice Association model internal medicine practices. RESEARCH DESIGN AND METHODS:Nine practices providing care to managed care patients were ...

journal_title：Diabetes care

authors： Ilag LL,Martin CL,Tabaei BP,Isaman DJ,Burke R,Greene DA,Herman WH

更新日期：2003-10-01 00:00:00

abstract：OBJECTIVE:Available basal insulin formulations do not provide a constant and reliable 24-h insulin supply. We compared the efficacy and safety of glargine (a long-acting insulin analog) and NPH insulins in insulin-naive type 2 diabetic patients treated with oral antidiabetic agents. RESEARCH DESIGN AND METHODS:There w...

journal_title：Diabetes care

authors： Yki-Järvinen H,Dressler A,Ziemen M,HOE 901\/300s Study Group.

更新日期：2000-08-01 00:00:00

abstract：OBJECTIVE:To assess the effects of empagliflozin, a selective sodium-glucose cotransporter 2 (SGLT2) inhibitor, on broad biological systems through proteomics. RESEARCH DESIGN AND METHODS:Aptamer-based proteomics was used to quantify 3,713 proteins in 144 paired plasma samples obtained from 72 participants across the ...

journal_title：Diabetes care

authors： Ferrannini E,Murthy AC,Lee YH,Muscelli E,Weiss S,Ostroff RM,Sattar N,Williams SA,Ganz P

更新日期：2020-09-01 00:00:00

abstract：OBJECTIVE:Intensive lifestyle intervention significantly reduced diabetes incidence among the participants in the Finnish Diabetes Prevention Study. We investigated whether and to what extent risk factors for type 2 diabetes and other baseline characteristics of the study participants modified the effectiveness of the ...

journal_title：Diabetes care

authors： Lindström J,Peltonen M,Eriksson JG,Aunola S,Hämäläinen H,Ilanne-Parikka P,Keinänen-Kiukaanniemi S,Uusitupa M,Tuomilehto J,Finnish Diabetes Prevention Study (DPS) Group.

更新日期：2008-05-01 00:00:00

abstract：:OBJECTIVE--To assess the relationship between family history and different types of obesity and change in obesity in a longitudinal population study. RESEARCH DESIGN AND METHODS--A longitudinal population study of 1462 randomly selected women (38-60 yr old) was conducted in Göteborg, Sweden, in 1968-69. The women were...

journal_title：Diabetes care

authors： Lapidus L,Bengtsson C,Lissner L,Smith U

更新日期：1992-11-01 00:00:00

abstract：OBJECTIVE:To assess the efficacy and safety of initial combination therapy with sitagliptin and metformin in patients with type 2 diabetes and inadequate glycemic control on diet and exercise. RESEARCH DESIGN AND METHODS:In a 24-week, randomized, double-blind, placebo-controlled, parallel-group study, 1,091 patients w...

journal_title：Diabetes care

authors： Goldstein BJ,Feinglos MN,Lunceford JK,Johnson J,Williams-Herman DE,Sitagliptin 036 Study Group.

更新日期：2007-08-01 00:00:00

abstract：:Enzymatic electrodes are described for the specific and sensitive determination of glucose in blood. The probes are based on the conversion of B-D-glucose by glucose oxidase chemically attached to the surface of a Pt electrode. The peroxide liberated is sensed by measurement of the current generated at +0.7 volts vs. ...

journal_title：Diabetes care

authors： Guilbault GG

更新日期：1982-05-01 00:00:00

abstract：OBJECTIVE:Women with preexisting (type 1 or type 2) diabetes experience an increased risk of serious adverse pregnancy outcomes. It is not known, however, how these risks change between the first and second pregnancy and whether there is an increased risk of recurrence. This study describes the absolute risks and recur...

journal_title：Diabetes care

authors： Tennant PW,Bilous RW,Prathapan S,Bell R

更新日期：2015-04-01 00:00:00

abstract：OBJECTIVE:Congenital generalized lipodystrophy (CGL) is an autosomal recessive genetic disorder characterized by almost complete absence of adipose tissue, muscular appearance, and severe insulin resistance since birth. We investigated whether insulin resistance in CGL patients is associated with abnormal muscle morpho...

journal_title：Diabetes care

authors： Garg A,Stray-Gundersen J,Parsons D,Bertocci LA

更新日期：2000-10-01 00:00:00

abstract：:We examined the clinical and epidemiologic characteristics of diabetic subjects ascertained from five different sources (hospital, private practice, specialist practice, nursing home, and prevalence survey) in a medium-sized upstate New York community. Patients were categorized using the National Diabetes Data Group c...

journal_title：Diabetes care

authors： Rothenberg RB,Olsen CL,Schnure JJ,Gerber TM,Cohen J,Curtis GB,Jesserer J,Roach J,Wirth C

更新日期：1985-09-01 00:00:00

abstract：OBJECTIVE:To determine the prevalence of IGT and diabetes and identify the occurrence of CVD and its risk factors. RESEARCH DESIGN AND METHODS:This study was a population-based, cross-sectional study of 110,660 residents, 25-74 yr of age of DaQing, Hei Long Jiang Province, China. RESULTS:Using 1985 WHO criteria, 577 ...

journal_title：Diabetes care

authors： Pan XR,Hu YH,Li GW,Liu PA,Bennett PH,Howard BV

更新日期：1993-01-01 00:00:00

abstract：OBJECTIVE:To test the utility of homeostasis model assessment (HOMA) in predicting insulin sensitivity [x10(- 4) min(-1)/(microIU/ml)] in children and to develop and compare two new prediction equations for insulin sensitivity in children using demographic and anthropometric measures in the presence or absence of fasti...

journal_title：Diabetes care

authors： Huang TT,Johnson MS,Goran MI

更新日期：2002-07-01 00:00:00

abstract：OBJECTIVE:To explore the relationship between the genetic polymorphisms of PPARgamma (Pro12Ala, C1431T, and C-2821T) and the risk of ischemic stroke and to investigate whether these genetic polymorphisms of PPARgamma would modify the risk of ischemic stroke among patients with hypertension or diabetes. RESEARCH DESIGN...

journal_title：Diabetes care

authors： Hsieh FI,Lo WC,Lin HJ,Hsieh YC,Lien LM,Bai CH,Tseng HP,Chiou HY

更新日期：2009-11-01 00:00:00

abstract：OBJECTIVE:The purpose of the 1992 Singapore National Health Survey was to determine the current distribution of major noncommunicable diseases and their risk factors, including the prevalence of diabetes and dyslipidemia, in Singapore. RESEARCH DESIGN AND METHODS:A combination of disproportionate stratified sampling a...

journal_title：Diabetes care

authors： Tan CE,Emmanuel SC,Tan BY,Jacob E

更新日期：1999-02-01 00:00:00

abstract：OBJECTIVE:The role of fibrosis in early progressive renal decline in type 2 diabetes is unknown. Circulating WFDC2 (WAP four-disulfide core domain protein 2) and matrix metalloproteinase 7 (MMP-7; Matrilysin) are postulated to be biomarkers of renal fibrosis. This study examined an association of circulating levels of ...

journal_title：Diabetes care

authors： Ihara K,Skupien J,Kobayashi H,Md Dom ZI,Wilson JM,O'Neil K,Badger HS,Bowsman LM,Satake E,Breyer MD,Duffin KL,Krolewski AS

更新日期：2020-11-01 00:00:00

abstract：OBJECTIVE:The present study was designed to assess the effect of magnesium plus zinc, vitamins C plus E, and a combination of these micronutrients on nephropathy indexes in type 2 diabetic patients. RESEARCH DESIGN AND METHODS:In a randomized, double-blind, placebo-controlled clinical trial, 69 type 2 diabetic patient...

journal_title：Diabetes care

authors： Farvid MS,Jalali M,Siassi F,Hosseini M

更新日期：2005-10-01 00:00:00

abstract：OBJECTIVE:To determine the effect of diabetes on thyroid hormone and thyroxine-binding globulin (TBG) concentrations during puberty. RESEARCH DESIGN AND METHODS:Total thyroxine (TT4), free thyroxine (FT4), and TBG levels of 171 thyroid microsomal antibody-negative subjects with normal thyroid-stimulating hormone (TSH)...

journal_title：Diabetes care

authors： Connors MH,Dunger DB,Chapel H,Jefferson I,Jowett TP,Edwards PR

更新日期：1996-03-01 00:00:00

abstract：OBJECTIVE:This study compared diabetes Treatment As Usual (TAU) with Pathways To Change (PTC), an intervention developed from the Transtheoretical Model of Change (TTM), to determine whether the PTC intervention would result in greater readiness to change, greater increases in self-care, and improved diabetes control. ...

journal_title：Diabetes care

authors： Jones H,Edwards L,Vallis TM,Ruggiero L,Rossi SR,Rossi JS,Greene G,Prochaska JO,Zinman B,Diabetes Stages of Change (DiSC) Study.

更新日期：2003-03-01 00:00:00

abstract：OBJECTIVE:To determine whether overweight Latino children with impaired fasting glucose (IFG) (> or = 100 mg/dl) have increased insulin resistance or decreased beta-cell function compared with those with normal fasting glucose (NFG). RESEARCH DESIGN AND METHODS:We studied 207 healthy overweight Latino children, aged 8...

journal_title：Diabetes care

authors： Weigensberg MJ,Ball GD,Shaibi GQ,Cruz ML,Goran MI

更新日期：2005-10-01 00:00:00

abstract：OBJECTIVE:Inflammatory processes have been implicated in the pathogenesis of painful neuropathy in rodents, but the relationship between inflammatory biomarkers and painful distal sensorimotor polyneuropathy (DSPN) has not been assessed in population-based studies. Therefore, we investigated whether circulating levels ...

journal_title：Diabetes care

authors： Herder C,Bongaerts BW,Rathmann W,Heier M,Kowall B,Koenig W,Thorand B,Roden M,Meisinger C,Ziegler D

更新日期：2015-01-01 00:00:00

abstract：OBJECTIVE:Low vitamin D status is common among healthy black and white adolescents residing at southern U.S. latitudes with a year-round sunny climate. Thus we aimed to study the relationships between circulating 25-hydroxyvitamin D [25(OH)D] and cardiometabolic risk factors in this population. RESEARCH DESIGN AND MET...

journal_title：Diabetes care

authors： Parikh S,Guo DH,Pollock NK,Petty K,Bhagatwala J,Gutin B,Houk C,Zhu H,Dong Y

更新日期：2012-05-01 00:00:00

abstract：OBJECTIVE:Diabetes is associated with oxidative stress and increased mortality, but a possible correlation between leukocyte-endothelium interactions, oxidative stress, and silent myocardial ischemia (SMI) is yet to be confirmed. RESEARCH DESIGN AND METHODS:Mitochondrial dysfunction and interactions between leukocytes...

journal_title：Diabetes care

authors： Hernandez-Mijares A,Rocha M,Rovira-Llopis S,Bañuls C,Bellod L,de Pablo C,Alvarez A,Roldan-Torres I,Sola-Izquierdo E,Victor VM

更新日期：2013-06-01 00:00:00

abstract：OBJECTIVE:To determine the pharmacokinetic (PK) and glucodynamic (GD) dose response of human insulin inhalation powder (HIIP) delivered via AIR particle technology and dose equivalence to subcutaneous (SC) insulin lispro. RESEARCH DESIGN AND METHODS:Twenty healthy, nonsmoking, male or female subjects (aged 29.6 +/- 6....

journal_title：Diabetes care

authors： Rave KM,Nosek L,de la Peña A,Seger M,Ernest CS 2nd,Heinemann L,Batycky RP,Muchmore DB

更新日期：2005-10-01 00:00:00

abstract：OBJECTIVE:Preclinical data suggest that linagliptin, a dipeptidyl peptidase-4 inhibitor, may lower urinary albumin excretion. The ability of linagliptin to lower albuminuria on top of renin-angiotensin-aldosterone system (RAAS) inhibition in humans was analyzed by pooling data from four similarly designed, 24-week, ran...

journal_title：Diabetes care

authors： Groop PH,Cooper ME,Perkovic V,Emser A,Woerle HJ,von Eynatten M

更新日期：2013-11-01 00:00:00

abstract：OBJECTIVE:To estimate the prevalence of known diabetes in a Swedish county (Skaraborg) and to evaluate capture-recapture methods for validation of the diabetes prevalence. RESEARCH DESIGN AND METHODS:Four sources were used to find known diabetic patients: 1) the Skaraborg Diabetes Registry (SDR), a case-finding invent...

journal_title：Diabetes care

authors： Berger B,Stenström G,Chang YF,Sundkvist G

更新日期：1998-04-01 00:00:00

abstract：OBJECTIVE:To compare lifestyle factors, cardiovascular risk factors, and coronary artery calcium (CAC) and abdominal aortic calcium (AAC) levels in Hispanic and non-Hispanic white (NHW) individuals with type 2 diabetes. RESEARCH DESIGN AND METHODS:We recently demonstrated in a small group of nonreferred, healthy, nond...

journal_title：Diabetes care

authors： Reaven PD,Sacks J,Investigators for the Veterans Affairs Cooperative Study of Glycemic Control and Complications in Diabetes Mellitus Type 2.

更新日期：2004-05-01 00:00:00

abstract：OBJECTIVE:Our aim was to analyze the performance of two scores developed for predicting diabetes in nontransplant populations for identifying kidney transplant recipients with a higher new-onset diabetes mellitus after transplantation (NODAT) risk beyond the first year after transplantation. RESEARCH DESIGN AND METHOD...

journal_title：Diabetes care

authors： Rodrigo E,Santos L,Piñera C,Millán JC,Quintela ME,Toyos C,Allende N,Gómez-Alamillo C,Arias M

更新日期：2012-03-01 00:00:00

abstract：:Morphologic characteristics of insulin precipitates were examined by both scanning and transmission electron microscopy. Insulin precipitate obtained after 1 wk of in vivo storage in an implanted dog reservoir was compared with insulin precipitate produced in vitro by isoelectric precipitation, acid-freeze-heat precip...

journal_title：Diabetes care

authors： Schade DS,Eaton RP,DeLongo J,Saland LC,Ladman AJ,Carlson GA

更新日期：1982-01-01 00:00:00