The clinical pharmacology of human insulin (Novo) in normal subjects.

abstract：OBJECTIVE:The performance of glycated hemoglobin (HbA1c) and fasting plasma glucose (FPG) was compared in screening for diabetes by an oral glucose tolerance test (OGTT) in patients undergoing coronary angiography (CAG). RESEARCH DESIGN AND METHODS:Patients without known diabetes admitted for CAG were eligible. OGTT a...

journal_title：Diabetes care

authors： Wang JS,Lee IT,Lee WJ,Lin SY,Fu CP,Ting CT,Lee WL,Liang KW,Sheu WH

更新日期：2013-05-01 00:00:00

abstract：OBJECTIVE:In cross-sectional studies of subjects with IDDM, the relationship between suboptimal pubertal growth, glycemic control, and abnormal insulin-like growth factor I (IGF-I) levels has proved difficult to define. The objective of this study was to examine these relationships in a longitudinal prospective study. ...

journal_title：Diabetes care

authors： Ahmed ML,Connors MH,Drayer NM,Jones JS,Dunger DB

更新日期：1998-05-01 00:00:00

abstract：OBJECTIVE:Recently, the Nateglinide and Valsartan in Impaired Glucose Tolerance Outcomes Research Trial demonstrated that treatment with the angiotensin receptor blocker (ARB) valsartan for 5 years resulted in a relative reduction of 14% in the incidence of type 2 diabetes in subjects with impaired glucose metabolism (...

journal_title：Diabetes care

authors： van der Zijl NJ,Moors CC,Goossens GH,Hermans MM,Blaak EE,Diamant M

更新日期：2011-04-01 00:00:00

abstract：OBJECTIVE:Bimodality in the distribution of glucose has been used to define the cut point for the diagnosis of diabetes. Previous studies on bimodality have primarily been in populations with a high prevalence of type 2 diabetes, including one study in a white Caucasian population. All studies included participants wit...

journal_title：Diabetes care

authors： Vistisen D,Colagiuri S,Borch-Johnsen K,DETECT-2 Collaboration.

更新日期：2009-03-01 00:00:00

abstract：OBJECTIVE:To test the effect of an automated system providing real-time estimates of HbA(1c), glucose variability, and risk for hypoglycemia. RESEARCH DESIGN AND METHODS:For 1 year, 120 adults with type 1 diabetes (69 female/51 male, age = 39.1 [14.3] years, duration of diabetes 20.3 [12.9] years, HbA(1c) = 8.0 [1.5])...

journal_title：Diabetes care

authors： Kovatchev BP,Mendosa P,Anderson S,Hawley JS,Ritterband LM,Gonder-Frederick L

更新日期：2011-02-01 00:00:00

abstract：:Enzymatic electrodes are described for the specific and sensitive determination of glucose in blood. The probes are based on the conversion of B-D-glucose by glucose oxidase chemically attached to the surface of a Pt electrode. The peroxide liberated is sensed by measurement of the current generated at +0.7 volts vs. ...

journal_title：Diabetes care

authors： Guilbault GG

更新日期：1982-05-01 00:00:00

abstract：:A rapid paper-strip test for the semiquantitating 3-hydroxybutyrate (3-OHBA) has been developed. The color develops within 5 min after applying the serum to the paper strip, and the purple color was read either visually or by reflectance meter. This can detect 3-OHBA levels as low as 0.1 mmol/L up to 2.0 mmol/L. The m...

journal_title：Diabetes care

authors： Harano Y,Suzuki M,Kojima H,Kashiwagi A,Hidaka H,Shigeta Y

更新日期：1984-09-01 00:00:00

abstract：:Glycosylated serum protein (GSP) and glycosylated hemoglobin (GHb) were measured in 263 insulin-dependent and 41 non-insulin-dependent diabetic subjects. Both indices provided useful information in type II diabetes, but were extremely poor in judging control in type I diabetes. In both groups, there was poor correlati...

journal_title：Diabetes care

authors： Mehl TD,Wenzel SE,Russell B,Gardner D,Merimee TJ

更新日期：1983-01-01 00:00:00

abstract：:A small and inexpensive computer was programmed to assist patients in making decisions regarding insulin delivery using constant subcutaneous infusion systems. Insulin dosage was based on gender, pre- and postprandial blood glucose, between-meal blood glucose, patient weight, time of day, and when appropriate, the car...

journal_title：Diabetes care

authors： Chanoch LH,Jovanovic L,Peterson CM

更新日期：1985-03-01 00:00:00

abstract：OBJECTIVE:To assess the acceptability of specially designed socks to provide satisfactory pressure relief in the insensitive, high-risk, diabetic foot. We have conducted a longitudinal multicenter patient evaluation study to assess the acceptability of such hosiery in neuropathic diabetic patients. RESEARCH DESIGN AND...

journal_title：Diabetes care

authors： Murray HJ,Veves A,Young MJ,Richie DH,Boulton AJ

更新日期：1993-08-01 00:00:00

abstract：OBJECTIVE:This study examined associations between BMI and mortality in individuals with normoglycemia, impaired fasting glucose (IFG), newly diagnosed diabetes, and prevalent diabetes and identified BMI ranges associated with the lowest mortality in each group. RESEARCH DESIGN AND METHODS:A total of 12,815,006 adults...

journal_title：Diabetes care

authors： Lee EY,Lee YH,Yi SW,Shin SA,Yi JJ

更新日期：2017-08-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to estimate how much at-risk individuals are willing to pay for type 2 diabetes primary prevention programs. RESEARCH DESIGN AND METHODS:An Internet-based, choice-format conjoint survey was presented to individuals at elevated risk for type 2 diabetes. Hypothetical diabetes risk...

journal_title：Diabetes care

authors： Johnson FR,Manjunath R,Mansfield CA,Clayton LJ,Hoerger TJ,Zhang P

更新日期：2006-06-01 00:00:00

abstract：OBJECTIVE:To investigate the relationship between lifestyle counseling in primary care settings and clinical outcomes in patients with diabetes. RESEARCH DESIGN AND METHODS:We retrospectively studied hyperglycemic adults with diabetes treated at primary care practices between 2000 and 2014. We analyzed the relationshi...

journal_title：Diabetes care

authors： Zhang H,Goldberg SI,Hosomura N,Shubina M,Simonson DC,Testa MA,Turchin A

更新日期：2019-09-01 00:00:00

abstract：:Seventeen diabetic subjects requiring insulin and who exhibited glycemic stability over a 9-12-mo control period received 5 g of pectin with each meal and at bedtime for 3 mo. Hemoglobin A1c (HbA1c) and glycosylated serum protein were measured in each patient on multiple occasions to assess glycemic control. No clear-...

journal_title：Diabetes care

authors： Gardner DF,Schwartz L,Krista M,Merimee TJ

更新日期：1984-03-01 00:00:00

abstract：OBJECTIVE:Stress hyperglycemia has been associated with increased mortality in patients with myocardial infarction (MI). We examined the association between plasma glucose levels, circulating inflammatory markers, T-cell activation, and functional cardiac outcome in patients with first MI. RESEARCH DESIGN AND METHODS:...

journal_title：Diabetes care

authors： Marfella R,Siniscalchi M,Esposito K,Sellitto A,De Fanis U,Romano C,Portoghese M,Siciliano S,Nappo F,Sasso FC,Mininni N,Cacciapuoti F,Lucivero G,Giunta R,Verza M,Giugliano D

更新日期：2003-11-01 00:00:00

abstract：:To evaluate the development of autonomic neuropathy, 23 patients with a moderate (group A) and 18 patients with a long (group B) duration of diabetes and without symptoms of autonomic neuropathy were re-investigated 6 yr after the initial studies. Autonomic nerve function was evaluated from heart reactions to deep bre...

journal_title：Diabetes care

authors： Sundkvist G,Lilja B

更新日期：1985-03-01 00:00:00

abstract：OBJECTIVE:To estimate the prevalence of severe diabetic complications. RESEARCH DESIGN AND METHODS:We surveyed the data systems of the IHS and local care providers to identify all AI/AN people with any of three diabetic complications: retinopathy needing one or more laser treatments, ESRD needing dialysis, and one or ...

journal_title：Diabetes care

authors： Freeman WL,Hosey GM

更新日期：1993-01-01 00:00:00

abstract：OBJECTIVE:To evaluate and validate appropriate premeal insulin dose reductions for postprandial exercises of different intensities and durations to minimize the risk of exercise-induced hypoglycemia in type 1 diabetic subjects. RESEARCH DESIGN AND METHODS:Eight male type 1 diabetic patients on a basal-bolus insulin re...

journal_title：Diabetes care

authors： Rabasa-Lhoret R,Bourque J,Ducros F,Chiasson JL

更新日期：2001-04-01 00:00:00

abstract：OBJECTIVE:High triglyceride (TG) levels and low HDL cholesterol (HDL-C) levels are risk factors for cardiovascular disease. It is unclear whether this relationship depends on glycemic dysregulation, sex, or LDL cholesterol (LDL-C) level. RESEARCH DESIGN AND METHODS:We studied 3,216 participants (40% men, 41% with diab...

journal_title：Diabetes care

authors： Lee JS,Chang PY,Zhang Y,Kizer JR,Best LG,Howard BV

更新日期：2017-04-01 00:00:00

abstract：OBJECTIVE:To determine the rheological properties of polymorphonuclear leukocytes (PMN) from non-insulin-dependent diabetes mellitus (NIDDM) patients. RESEARCH DESIGN AND METHODS:The deformability of PMN from 33 NIDDM subjects, 13 with impaired glucose tolerance (IGT), and 22 with normal glucose tolerance (NGT) was st...

journal_title：Diabetes care

authors： Pécsvarády Z,Fisher TC,Darwin CH,Fabók A,Maqueda TS,Saad MF,Meiselman HJ

更新日期：1994-01-01 00:00:00

abstract：OBJECTIVE:To determine if nephropathy in NIDDM is associated with cellular markers for hypertension. RESEARCH DESIGN AND METHODS:We compared 11 patients with clinical diabetic nephropathy with 15 control subjects with no diabetic nephropathy. The patients were white and had had NIDDM for > or = 9 yr and serum creatini...

journal_title：Diabetes care

authors： Herman WH,Prior DE,Yassine MD,Weder AB

更新日期：1993-05-01 00:00:00

abstract：OBJECTIVE:Success after islet transplantation can be defined in terms of insulin independence, C-peptide secretion, or glycemic control. These measures are interdependent and all need to be considered in evaluating beta-cell function after islet transplantation. For the current study, a composite beta-score was develop...

journal_title：Diabetes care

authors： Ryan EA,Paty BW,Senior PA,Lakey JR,Bigam D,Shapiro AM

更新日期：2005-02-01 00:00:00

abstract：OBJECTIVE:We examined the effects of metformin on diabetes prevention and the subgroups that benefited most over 15 years in the Diabetes Prevention Program (DPP) and its follow-up, the Diabetes Prevention Program Outcomes Study (DPPOS). RESEARCH DESIGN AND METHODS:During the DPP (1996-2001), adults at high risk of de...

journal_title：Diabetes care

authors： Diabetes Prevention Program Research Group.

更新日期：2019-04-01 00:00:00

abstract：OBJECTIVE:To compare the diagnostic properties of a nonmydriatic 200° ultra-widefield scanning laser ophthalmoscope (SLO) versus mydriatic Early Treatment of Diabetic Retinopathy Study (ETDRS) 7-field photography for diabetic retinopathy (DR) screening. RESEARCH DESIGN AND METHODS:A consecutive series of 212 eyes of 1...

journal_title：Diabetes care

authors： Kernt M,Hadi I,Pinter F,Seidensticker F,Hirneiss C,Haritoglou C,Kampik A,Ulbig MW,Neubauer AS

更新日期：2012-12-01 00:00:00

abstract：:OBJECTIVE--To determine the prevalence of non-insulin-dependent diabetes mellitus (NIDDM), impaired glucose tolerance (IGT), and hypertension in a rural community of Bangladesh. RESEARCH DESIGN AND METHODS--A cluster sampling of 1,005 subjects > 15 years of age in the rural community of Dohar was investigated. Capilla...

journal_title：Diabetes care

authors： Abu Sayeed M,Banu A,Khan AR,Hussain MZ

更新日期：1995-04-01 00:00:00

abstract：:There is increasing evidence that an ongoing cytokine-induced acute-phase response (sometimes called low-grade inflammation, but part of a widespread activation of the innate immune system) is closely involved in the pathogenesis of type 2 diabetes and associated complications such as dyslipidemia and atherosclerosis....

journal_title：Diabetes care

authors： Pickup JC

更新日期：2004-03-01 00:00:00

abstract：OBJECTIVE:To describe the clinical and immunologic characteristics of fulminant type 1 diabetes, a novel subtype of type 1 diabetes, we conducted a nationwide survey. RESEARCH DESIGN AND METHODS:History and laboratory data, including islet-related autoantibodies, were examined in 222 patients with fulminant and nonful...

journal_title：Diabetes care

authors： Imagawa A,Hanafusa T,Uchigata Y,Kanatsuka A,Kawasaki E,Kobayashi T,Shimada A,Shimizu I,Toyoda T,Maruyama T,Makino H

更新日期：2003-08-01 00:00:00

abstract：OBJECTIVE:To determine the usefulness of measuring hemoglobin A(1c) (A1C), alone or combined with the fasting glucose test, compared with the oral glucose tolerance test (OGTT) for the reassessment of the carbohydrate metabolism status in postpartum women with a history of gestational diabetes mellitus (GDM). RESEARCH...

journal_title：Diabetes care

authors： Picón MJ,Murri M,Muñoz A,Fernández-García JC,Gomez-Huelgas R,Tinahones FJ

更新日期：2012-08-01 00:00:00

abstract：OBJECTIVE:To study the effect of vitamin E supplementation on platelet hyperaggregability in type 1 diabetic patients. RESEARCH DESIGN AND METHODS:Written informed consent according to the Institutional Review Board on Human Experimentation guidelines was obtained from diabetic patients (n = 29) and their age-matched ...

journal_title：Diabetes care

authors： Jain SK,Krueger KS,McVie R,Jaramillo JJ,Palmer M,Smith T

更新日期：1998-09-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to compare the University of Texas (UT) and Site, Ischemia, Neuropathy, Bacterial Infection, and Depth (SINBAD) foot ulcer scores in predicting ulcer outcome within a routine diabetes foot clinic. RESEARCH DESIGN AND METHODS:From 2006 to 2018, data were collected from all patients a...

journal_title：Diabetes care

authors： Leese GP,Soto-Pedre E,Schofield C

更新日期：2021-02-01 00:00:00