Abstract:
OBJECTIVE:The performance of glycated hemoglobin (HbA1c) and fasting plasma glucose (FPG) was compared in screening for diabetes by an oral glucose tolerance test (OGTT) in patients undergoing coronary angiography (CAG). RESEARCH DESIGN AND METHODS:Patients without known diabetes admitted for CAG were eligible. OGTT and HbA1c were assessed 2-4 weeks after hospital discharge. The performance of HbA1c and FPG was evaluated by using receiver operating characteristic (ROC) analysis. RESULTS:Diabetes was diagnosed in 83 of 400 patients (20.8%). The area under the ROC curve was higher for FPG than for HbA1c (0.81 vs. 0.73, P = 0.032). We proposed a screening algorithm and validated it in another 170 patients. Overall, this algorithm reduced the number of OGTTs by 71.4% (sensitivity 74.4%, specificity 100%). CONCLUSIONS:FPG performed better than HbA1c in screening for diabetes in patients undergoing CAG. A screening algorithm might help to reduce the number of OGTTs.
journal_name
Diabetes Carejournal_title
Diabetes careauthors
Wang JS,Lee IT,Lee WJ,Lin SY,Fu CP,Ting CT,Lee WL,Liang KW,Sheu WHdoi
10.2337/dc12-1434subject
Has Abstractpub_date
2013-05-01 00:00:00pages
1138-40issue
5eissn
0149-5992issn
1935-5548pii
dc12-1434journal_volume
36pub_type
杂志文章相关文献
DIABETES CARE文献大全abstract::OBJECTIVE--To determine the prevalence of non-insulin-dependent diabetes mellitus (NIDDM), impaired glucose tolerance (IGT), and hypertension in a rural community of Bangladesh. RESEARCH DESIGN AND METHODS--A cluster sampling of 1,005 subjects > 15 years of age in the rural community of Dohar was investigated. Capilla...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/diacare.18.4.555
更新日期:1995-04-01 00:00:00
abstract:OBJECTIVE:To prospectively examine the effect of weight loss 1 year after laparoscopic adjustable gastric band surgery on a broad range of health outcomes in 50 diabetic subjects. RESEARCH DESIGN AND METHODS:A total of 50 (17 men, 33 women) of 51 patients with type 2 diabetes, from a total of 500 consecutive patients,...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/diacare.25.2.358
更新日期:2002-02-01 00:00:00
abstract:OBJECTIVE:We have previously shown that 300 kcal from glucose intake induces a significant increase in reactive oxygen species (ROS) generation and nuclear factor-kappaB (NF-kappaB) binding in the circulating mononuclear cells in healthy normal subjects. We hypothesized that the intake of 300 calories as orange juice o...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/dc06-1458
更新日期:2007-06-01 00:00:00
abstract:OBJECTIVE:To describe the relative contributions of neurological and vascular abnormalities to the overall risk of diabetic foot ulceration. RESEARCH DESIGN AND METHODS:A case-control study of diabetic veterans from the Seattle Veterans Affairs Medical Center was conducted using data collected from 46 patients with di...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/diacare.18.2.216
更新日期:1995-02-01 00:00:00
abstract::Use of pure porcine insulin versus partially purified insulin of bovine/porcine origin might be expected to have certain clinical benefits, e.g., a lower incidence of skin reactions, a lower insulin dosage, better diabetes regulation, and greater preservation of endogenous insulin secretion. To test this hypothesis, w...
journal_title:Diabetes care
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.2337/diacare.10.3.337
更新日期:1987-05-01 00:00:00
abstract:OBJECTIVE:To compare the weight losses of black and white patients with NIDDM treated in a year-long behavioral weight loss program. RESEARCH DESIGN AND METHODS:Subjects were randomly assigned to a behavioral program that either used a low-calorie diet throughout or included two 12-week periods of a very-low calorie d...
journal_title:Diabetes care
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.2337/diacare.19.5.409
更新日期:1996-05-01 00:00:00
abstract::OBJECTIVE- We examined the influence of a moderately elevated serum ferritin level at entry to care on the risk of gestational diabetes mellitus (GDM) and a possible mechanism (increased iron stores versus inflammation). RESEARCH DESIGN AND METHODS- In a prospective observational study with 1,456 healthy pregnant wome...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/diacare.2951077
更新日期:2006-05-01 00:00:00
abstract:OBJECTIVE:To promote foot screening of inpatients with diabetes, we simplified sensory testing to lightly touching the tips of the first, third, and fifth toes (the Ipswich Touch Test [IpTT]). RESEARCH DESIGN AND METHODS:Respective performances of the IpTT and 10-g monofilament (MF) were compared with a vibration perc...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/dc11-0156
更新日期:2011-07-01 00:00:00
abstract:OBJECTIVE:The levels of the surrogate markers of cholesterol absorption (cholestanol and plant sterols) and synthesis (cholesterol precursors) in serum have suggested that in adult type 1 diabetes, cholesterol absorption is high and synthesis is low compared with type 2 diabetic or control subjects. Accordingly, these ...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/dc05-2235
更新日期:2006-10-01 00:00:00
abstract:OBJECTIVE:To determine whether clinically significant differences exist in fasting blood glucose (BG) at the forearm, palm, and thigh relative to the fingertip; to assess the impact of prandial status by comparing BG between alternative sites and the fingertip at several time intervals after carbohydrate intake; to ass...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/diacare.26.4.981
更新日期:2003-04-01 00:00:00
abstract:OBJECTIVE:To implement an educational program in 10 Latin American countries and to evaluate its effect on the clinical, biochemical, and therapeutic aspects as well as the economic cost of diabetes. RESEARCH DESIGN AND METHODS:Educators from each participating country were previously trained to implement the educatio...
journal_title:Diabetes care
pub_type: 临床试验,杂志文章,多中心研究
doi:10.2337/diacare.24.6.1001
更新日期:2001-06-01 00:00:00
abstract:OBJECTIVE:To examine the factors that determine the blood pressure response to enalapril and nifedipine monotherapy in the treatment of hypertension associated with non-insulin-dependent diabetes mellitus (NIDDM). RESEARCH DESIGN AND METHODS:After a 6-week placebo baseline period, 102 hypertensive NIDDM patients were ...
journal_title:Diabetes care
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.2337/diacare.18.7.1001
更新日期:1995-07-01 00:00:00
abstract:OBJECTIVE:To evaluate and validate appropriate premeal insulin dose reductions for postprandial exercises of different intensities and durations to minimize the risk of exercise-induced hypoglycemia in type 1 diabetic subjects. RESEARCH DESIGN AND METHODS:Eight male type 1 diabetic patients on a basal-bolus insulin re...
journal_title:Diabetes care
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.2337/diacare.24.4.625
更新日期:2001-04-01 00:00:00
abstract::Our objective was to define glomerular filtration rate (GFR) and renal plasma flow (RPF) in Black Americans with non-insulin-dependent diabetes mellitus (NIDDM). This was a cross-sectional study of 71 Black NIDDM patients with diagnosed diabetes duration from 1 mo to 21 yr. Hyperglycemia was regulated and stabilized b...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/diacare.13.11.1186
更新日期:1990-11-01 00:00:00
abstract:OBJECTIVE:In recent years, a growing number of people with type 1 diabetes gained access to real-time continuous glucose monitoring (rtCGM). Long-term benefits of rtCGM are unclear because of a lack of large studies of long duration. We evaluated whether real-world rtCGM use up to 24 months offered benefits, particular...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/dc20-1531
更新日期:2020-12-01 00:00:00
abstract:OBJECTIVE:Direct medical cost of diabetes in the U.S. has been estimated to be 2.3 times higher relative to individuals without diabetes. This study examines trends in health care expenditures by expenditure category in U.S. adults with diabetes between 2002 and 2011. RESEARCH DESIGN AND METHODS:We analyzed 10 years o...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/dc15-0369
更新日期:2015-10-01 00:00:00
abstract:OBJECTIVE:Treatment guidelines for diabetes have become increasingly stringent as most research shows that more aggressive intervention reduces the risks for complications. Community data on the effect of these interventions are lacking. RESEARCH DESIGN AND METHODS:Changes in the pharmacologic treatment of diabetes, b...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/dc10-0678
更新日期:2010-11-01 00:00:00
abstract:OBJECTIVE:We previously showed that in patients with diabetes mellitus, glycated hemoglobin (HbA1c) monitoring outside international guidance on testing frequency is widespread. Here we examined the relationship between testing frequency and diabetes control to test the hypothesis that retest interval is linked to chan...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/dc14-0297
更新日期:2014-10-01 00:00:00
abstract:OBJECTIVE:To characterize physiologic subtypes of gestational diabetes mellitus (GDM). RESEARCH DESIGN AND METHODS:Insulin sensitivity and secretion were estimated in 809 women at 24-30 weeks' gestation, using oral glucose tolerance test-based indices. In women with GDM (8.3%), defects in insulin sensitivity or secret...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/dc15-2672
更新日期:2016-06-01 00:00:00
abstract::This study describes the pharmacokinetics of three intermediate-acting insulin preparations, NPH porcine insulin, NPH human insulin (recombinant DNA), and "Depot-A" insulin, a mixture of 20% regular and 80% NPH human insulin from Eli Lilly and Company. Metabolic healthy normal weight volunteers were selected for the s...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/diacare.5.2.s43
更新日期:1982-11-01 00:00:00
abstract:OBJECTIVE:Predictors of insulin resistance have hitherto only been examined in cross-sectional studies without information on lifestyle factors. Few researchers have measured insulin sensitivity directly and compared different metabolic and lifestyle predictors in a large population. RESEARCH DESIGN AND METHODS:Our ai...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/dc07-0360
更新日期:2007-11-01 00:00:00
abstract:OBJECTIVE:High levels of dietary fiber, especially soluble fiber, are recommended to lower serum cholesterol levels and improve glycemic control in patients with type 2 diabetes. It is not clear, however, how high levels of fiber affect mineral balance. RESEARCH DESIGN AND METHODS:In a randomized crossover study, 13 p...
journal_title:Diabetes care
pub_type: 杂志文章,随机对照试验
doi:10.2337/dc09-0126
更新日期:2009-06-01 00:00:00
abstract::The scientific literature demonstrates that fat replacers have a reasonable certainty of no harm. Whether they help produce desired health outcomes, i.e., decreased risk of coronary heart disease and certain types of cancer related to excess fat intake, weight reduction, changes in lipid profile, improved glycemic con...
journal_title:Diabetes care
pub_type: 杂志文章,评审
doi:10.2337/diacare.19.11.1294
更新日期:1996-11-01 00:00:00
abstract:OBJECTIVE:The association between changes in triglyceride concentrations over time and diabetes is unknown. We assessed whether two triglyceride determinations obtained 5 years apart can predict incident type 2 diabetes. RESEARCH DESIGN AND METHODS:Triglyceride levels at baseline (time 1) and 5 years later (time 2), f...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/dc08-0825
更新日期:2008-10-01 00:00:00
abstract:OBJECTIVE:The purpose of this study was to assess fertility in women with type 1 diabetes and the risk of congenital malformations in their offspring.
RESEARCH DESIGN AND METHODS:This was a register-based cohort study in Sweden. All 5,978 women hospitalized for type 1 diabetes at age journal_title:Diabetes care pub_type: 杂志文章 doi:10.2337/dc06-2574 更新日期:2007-09-01 00:00:00
abstract:OBJECTIVE:Hyperinsulinemia is often associated with several metabolic abnormalities and increased blood pressure, which are risk factors for cardiovascular disease. It has been hypothesized that insulin resistance may underlie all these features. However, recent data suggest that some links between insulin resistance a...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/diacare.29.02.06.dc05-1478
更新日期:2006-02-01 00:00:00
abstract::The history of the National Diabetes Advisory Board is reviewed, particularly from the perspective of the role of the board in advancing diabetes care. In addition, its potential future activities in the arena of translating research advances, for example, the results of the Diabetes Control and Complications Trial (D...
journal_title:Diabetes care
pub_type: 杂志文章
doi:
更新日期:1994-06-01 00:00:00
abstract:OBJECTIVE:To determine the proportion of patients with gestational diabetes mellitus (GDM) who have serological characteristics typical of IDDM. RESEARCH DESIGN AND METHODS:Islet cell antibodies (ICAs), insulin autoantibodies (IAAs), GAD65, and IA-2 antibodies were measured in 145 pregnant women with GDM, 33 with impa...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/diacare.20.1.81
更新日期:1997-01-01 00:00:00
abstract:OBJECTIVE:Mild demyelination may contribute more to the pathophysiology of nerve fiber injury in diabetic sensorimotor polyneuropathy (DSP) than previously thought. We investigated the clinical and electrodiagnostic classifications of nerve injury in diabetic patients to detect evidence of conduction slowing in DSP. R...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/dc13-0746
更新日期:2013-11-01 00:00:00
abstract:OBJECTIVE:To determine whether adolescents with type 1 diabetes have left ventricular functional changes at rest and during acute exercise and whether these changes are affected by metabolic control and diabetes duration. RESEARCH DESIGN AND METHODS:The study evaluated 53 adolescents with type 1 diabetes and 22 contro...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/dc11-2331
更新日期:2012-10-01 00:00:00