Serum lipids and the progression of nephropathy in type 1 diabetes.

abstract：OBJECTIVE:To compare the glycemic profiles of patients with type 1 diabetes treated with either an implantable insulin pump or pancreas or islet transplantation by the means of the continuous glucose monitoring system (CGMS; Minimed, Sylmar, CA). RESEARCH DESIGN AND METHODS:The CGMS enabled recording of subcutaneous g...

journal_title：Diabetes care

authors： Kessler L,Passemard R,Oberholzer J,Benhamou PY,Bucher P,Toso C,Meyer P,Penfornis A,Badet L,Wolf P,Colin C,Morel P,Pinget M,GRAGIL Group.

更新日期：2002-12-01 00:00:00

abstract：OBJECTIVE:Evidence that midregional fragment of pro-A-type natriuretic peptide (MR-proANP) is a marker of mortality in patients with type 2 diabetes is limited. Therefore, we aimed to investigate the capabilities of MR-proANP in predicting mortality. We also investigated whether MR-proANP influences the relationship be...

journal_title：Diabetes care

authors： van Hateren KJ,Landman GW,Kleefstra N,Groenier KH,Struck J,Navis GJ,Bakker SJ,Houweling ST,van der Meer K,Bilo HJ

更新日期：2013-05-01 00:00:00

abstract：:Fifty-one insulin-dependent diabetic patients, 26 children and 25 adults, participated in an open uncontrolled study of the safety and efficacy of human insulin (Novo). The patients, who had previously been treated exclusively with porcine insulin, were followed in two outpatient clinics during a 3-mo study period. Du...

journal_title：Diabetes care

authors： Lyngsøe J,Vestermark S

更新日期：1983-03-01 00:00:00

abstract：OBJECTIVE:The current standard for hospital glucose management is point-of-care (POC) testing. We conducted a randomized controlled trial of real-time continuous glucose monitoring (RT-CGM) compared with POC in a non-intensive care unit (ICU) hospital setting. RESEARCH DESIGN AND METHODS:A total of 110 adults with typ...

journal_title：Diabetes care

authors： Fortmann AL,Spierling Bagsic SR,Talavera L,Garcia IM,Sandoval H,Hottinger A,Philis-Tsimikas A

更新日期：2020-11-01 00:00:00

abstract：OBJECTIVE:To evaluate the utility of a semipermeable polymeric membrane dressing for the treatment of chronic diabetic foot ulcers. RESEARCH DESIGN AND METHODS:Nineteen subjects with either insulin-dependent diabetes mellitus (IDDM) or non-insulin-dependent diabetes mellitus (NIDDM) and foot ulcers were randomly assig...

journal_title：Diabetes care

authors： Blackman JD,Senseng D,Quinn L,Mazzone T

更新日期：1994-04-01 00:00:00

abstract：:Compared with control subjects, non-insulin-dependent diabetes mellitus (NIDDM) subjects had both quantitative and qualitative abnormalities in blood insulin and glucose concentrations. The purpose of this study was to determine whether and to what extent normally observed multiphasic patterns of insulin and glucose r...

journal_title：Diabetes care

authors： Calles-Escandon J,Jaspan J,Robbins DC

更新日期：1989-11-01 00:00:00

abstract：OBJECTIVE:Individuals with type 2 diabetes have high risk of late-life cognitive impairment, yet little is known about strategies to modify risk. Targeting insulin resistance and vascular complications-both associated with cognitive decline-may be a productive approach. We investigated whether dietary fat, which modula...

journal_title：Diabetes care

authors： Devore EE,Stampfer MJ,Breteler MM,Rosner B,Kang JH,Okereke O,Hu FB,Grodstein F

更新日期：2009-04-01 00:00:00

abstract：:The results of uncontrolled trials in immunomodulation of insulin-dependent diabetes mellitus (IDDM) led to randomized controlled trials in Canada and Europe. In the Canadian open study, the rate of clinical remissions (target control of glycemia maintained with less than or equal to 0.15 U.kg-1.day-1 insulin) was une...

journal_title：Diabetes care

authors： Dupré J,Stiller CR,Gent M,Donner A,von Graffenried B,Heinrichs D,Jenner M,Keown P,Mahon J,Martell R

更新日期：1988-11-01 00:00:00

abstract：OBJECTIVE:To compare A1C and fasting glucose for the diagnosis of diabetes among U.S. adults. RESEARCH DESIGN AND METHODS:This study included 6,890 adults (> or =20 years of age) from the 1999-2006 National Health and Nutrition Examination Survey without a self-reported history of diabetes who had fasted > or =9 h. A1...

journal_title：Diabetes care

authors： Carson AP,Reynolds K,Fonseca VA,Muntner P

更新日期：2010-01-01 00:00:00

abstract：OBJECTIVE:To assess the relationship between the insertion (I)/deletion (D) polymorphism of the ACE gene and arterial distensibility in patients with type 2 diabetes and healthy control subjects. RESEARCH DESIGN AND METHODS:Aortic and carotid arterial distensibility were evaluated by measuring aortic pulse-wave veloci...

journal_title：Diabetes care

authors： Taniwaki H,Kawagishi T,Emoto M,Shoji T,Hosoi M,Kogawa K,Nishizawa Y,Morii H

更新日期：1999-11-01 00:00:00

abstract：:Type 1 diabetes (T1D) and celiac disease (CeD) cluster in families and can occur in the same individual. Genetic loci have been associated with susceptibility to both diseases. Our aim was to explore the genetic differences between individuals developing both these diseases (double autoimmunity) versus those with only...

journal_title：Diabetes care

authors： Gutierrez-Achury J,Romanos J,Bakker SF,Kumar V,de Haas EC,Trynka G,Ricaño-Ponce I,Steck A,Type 1 Diabetes Genetics Consortium.,Chen WM,Onengut-Gumuscu S,Simsek S,Diabeter.,Rewers M,Mulder CJ,Liu E,Rich SS,Wijmenga C

更新日期：2015-10-01 00:00:00

abstract：:Adjustment algorithms for conventional insulin therapy must be tested for safety and efficacy before clinical implementation. We did this by computer simulation. Accordingly, a computer simulator of human intermediary metabolism created 10 randomly chosen diabetic subjects for study. All were well defined with respect...

journal_title：Diabetes care

authors： Albisser AM,Sozzi S,Strack TR

更新日期：1990-04-01 00:00:00

abstract：OBJECTIVE:To validate fasting indices of insulin sensitivity and secretion in a diverse pediatric population against gold standard estimates from euglycemic and hyperglycemic clamps. RESEARCH DESIGN AND METHODS:A total of 31 children (mean BMI 25.1 +/- 4.9 kg/m(2), mean age 8.7 +/- 1.4 years, 15 girls and 16 boys, 12 ...

journal_title：Diabetes care

authors： Uwaifo GI,Fallon EM,Chin J,Elberg J,Parikh SJ,Yanovski JA

更新日期：2002-11-01 00:00:00

abstract：:Specialists in childhood diabetes in North America were queried about the need for residential facilities for their patients with recurrent hospitalizations and school deficits due to family coping problems. Of 132 respondents, 115 indicated a need for 5-12% of their patients, a total of 530, close to the estimate of ...

journal_title：Diabetes care

authors： Rosenbloom AL

更新日期：1982-09-01 00:00:00

abstract：:Whereas self-monitoring of blood glucose (SMBG) is the recommended source of information on which to make self-care decisions, patients frequently use estimates of their own blood glucose (BG). This study evaluated whether patients with insulin-dependent diabetes mellitus (IDDM) could learn to improve accuracy of BG e...

journal_title：Diabetes care

authors： Cox DJ,Gonder-Frederick LA,Lee JH,Julian DM,Carter WR,Clarke WL

更新日期：1989-05-01 00:00:00

abstract：OBJECTIVE:To evaluate the association between the use of ACE inhibitors and hospital admission for severe hypoglycemia and to explore the effects of potential confounding variables on this relationship. RESEARCH DESIGN AND METHODS:The association between the use of ACE inhibitors and the incidence of hypoglycemia is c...

journal_title：Diabetes care

authors： Morris AD,Boyle DI,McMahon AD,Pearce H,Evans JM,Newton RW,Jung RT,MacDonald TM

更新日期：1997-09-01 00:00:00

abstract：OBJECTIVE:To examine the factors that determine the blood pressure response to enalapril and nifedipine monotherapy in the treatment of hypertension associated with non-insulin-dependent diabetes mellitus (NIDDM). RESEARCH DESIGN AND METHODS:After a 6-week placebo baseline period, 102 hypertensive NIDDM patients were ...

journal_title：Diabetes care

authors： Chan JC,Nicholls MG,Cheung CK,Law LK,Swaminathan R,Cockram CS

更新日期：1995-07-01 00:00:00

abstract：OBJECTIVE:Large prospective studies have demonstrated that optimum glycemic control is not routinely achieved in clinical practice. Barriers to optimal insulin therapy include hypoglycemia, weight gain, and suboptimal initiation and dose titration. This study compared two treatment algorithms for insulin glargine initi...

journal_title：Diabetes care

authors： Davies M,Storms F,Shutler S,Bianchi-Biscay M,Gomis R,ATLANTUS Study Group.

更新日期：2005-06-01 00:00:00

abstract：OBJECTIVE:To test the hypothesis that microalbuminuria may show an independent statistical association with diabetic neuropathy. RESEARCH DESIGN AND METHODS:An observational study of a prospectively identified cohort was conducted at the University Medical Center. The cohort consisted of 78 consecutive diabetic patien...

journal_title：Diabetes care

authors： Bell DS,Ketchum CH,Robinson CA,Wagenknecht LE,Williams BT

更新日期：1992-04-01 00:00:00

abstract：:In past studies on the psychological aspects of diabetes mellitus, symptoms of depression have been identified as the most common manifestation among diabetic patients. Other psychological manifestations have been anxiety, hypochondriasis, increased dependence and passivity, and poor self-image. Ten insulin-dependent ...

journal_title：Diabetes care

authors： Dupuis A

更新日期：1980-01-01 00:00:00

abstract：OBJECTIVE:Focusing health interventions in places with suboptimal glycemic control can help direct resources to neighborhoods with poor diabetes-related outcomes, but finding these areas can be difficult. Our objective was to use indirect measures versus a gold standard, population-based A1C registry to identify areas ...

journal_title：Diabetes care

authors： Lee DC,Jiang Q,Tabaei BP,Elbel B,Koziatek CA,Konty KJ,Wu WY

更新日期：2018-07-01 00:00:00

abstract：OBJECTIVE:To evaluate the relationship of impaired glucose tolerance (IGT) at baseline to coronary heart disease (CHD) incidence, and cardiovascular disease (CVD) and total mortality at follow-up, and to analyze whether the relationship is independent of the subsequent development of diabetes during follow-up. RESEARC...

journal_title：Diabetes care

authors： Qiao Q,Jousilahti P,Eriksson J,Tuomilehto J

更新日期：2003-10-01 00:00:00

abstract：OBJECTIVE:The impact of major affective disorders on the effectiveness of diabetes prevention programs at promoting health behaviors has not been established. We investigated whether depression modifies the effectiveness of two pragmatic diabetes prevention programs at promoting increased physical activity. RESEARCH D...

journal_title：Diabetes care

authors： Yates T,Gray LJ,Henson J,Edwardson CL,Khunti K,Davies MJ

更新日期：2019-10-01 00:00:00

abstract：OBJECTIVE:To assess the level of serum lipoprotein(a) [Lp(a)] in nonobese and obese NIDDM subjects with android body distribution. RESEARCH DESIGN AND METHODS:Serum Lp(a) levels were measured in 30 long-standing NIDDM patients (duration of diabetes 12.5 +/- 3 years, mean +/- SD), with 15 of the patients being obese of...

journal_title：Diabetes care

authors： Wassef N,Sidhom G,Zakareya el-K,Mohamed el-K

更新日期：1997-11-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to increase the cross-state comparability of diabetes mortality statistics related in the U.S. and Mexico. RESEARCH DESIGN AND METHODS:We used multinomial logistic regression to estimate the effects of individual and community factors on a death for which diabetes was recorded as on...

journal_title：Diabetes care

authors： Murray CJ,Dias RH,Kulkarni SC,Lozano R,Stevens GA,Ezzati M

更新日期：2008-03-01 00:00:00

abstract：OBJECTIVE:Success after islet transplantation can be defined in terms of insulin independence, C-peptide secretion, or glycemic control. These measures are interdependent and all need to be considered in evaluating beta-cell function after islet transplantation. For the current study, a composite beta-score was develop...

journal_title：Diabetes care

authors： Ryan EA,Paty BW,Senior PA,Lakey JR,Bigam D,Shapiro AM

更新日期：2005-02-01 00:00:00

abstract：OBJECTIVE:HbA1c is strongly related to the development of diabetes complications, but it is still controversial which HbA1c level to strive for in the treatment of type 1 diabetes. The aim of the current study was to evaluate HbA1c, followed from diagnosis, as a predictor of severe microvascular complications and to fo...

journal_title：Diabetes care

authors： Nordwall M,Abrahamsson M,Dhir M,Fredrikson M,Ludvigsson J,Arnqvist HJ

更新日期：2015-02-01 00:00:00

abstract：OBJECTIVE:To determine whether the severity of retinopathy is higher in a group of NIDDM patients with sBP greater than or equal to 140 mmHg compared with NIDDM patients with sBP less than 140 mmHg. RESEARCH DESIGN AND METHODS:Ophthalmoscopy and FAG were conducted among a group of NIDDM patients with either a sBP abov...

journal_title：Diabetes care

authors： Cignarelli M,De Cicco ML,Damato A,Paternostro A,Pagliarini S,Santoro S,Cardia L,De Pergola G,Giorgino R

更新日期：1992-08-01 00:00:00

abstract：OBJECTIVE:Proteoglycan metabolism is altered in diabetic patients. The xylosyltransferases (XTs) are the initial and rate-limiting enzymes in the biosynthesis of the glycosaminoglycan chains in proteoglycans. Here, we analyzed whether the changed proteoglycan metabolism leads to altered serum XT levels in diabetic pati...

journal_title：Diabetes care

authors： Götting C,Kuhn J,Kleesiek K

更新日期：2008-10-01 00:00:00

abstract：OBJECTIVE:To quantify the incremental survival benefit of the pancreas allograft in simultaneous pancreas-kidney (SPK) transplant recipients. RESEARCH DESIGN AND METHODS:Data from the national transplant database from 2000 to 2007 were analyzed. SPK recipients who had functioning allografts to 1-year post transplant (...

journal_title：Diabetes care

authors： Salvalaggio PR,Dzebisashvili N,Pinsky B,Schnitzler MA,Burroughs TE,Graff R,Axelrod DA,Brennan DC,Lentine KL

更新日期：2009-04-01 00:00:00