Effects of a home-based walking intervention on mobility and quality of life in people with diabetes and peripheral arterial disease: a randomized controlled trial.

abstract：OBJECTIVE:Independent association of chronic kidney disease (CKD) and proliferative diabetic retinopathy (PDR) with cardiovascular disease (CVD) has not been established. In the Joslin 50-Year Medalist study, characterizing individuals with type 1 diabetes for 50 years or more, we examined the associations of CKD and P...

journal_title：Diabetes care

authors： Gordin D,Harjutsalo V,Tinsley L,Fickweiler W,Sun JK,Forsblom C,Amenta PS,Pober D,D'Eon S,Khatri M,Stillman IE,Groop PH,Keenan HA,King GL

更新日期：2018-04-01 00:00:00

abstract：OBJECTIVE:This study evaluated the ability of the Building, Relating, Assessing, and Validating Outcomes (BRAVO) risk engine to accurately project cardiovascular outcomes in three major clinical trials-BI 10773 (Empagliflozin) Cardiovascular Outcome Event Trial in Type 2 Diabetes Mellitus Patients (EMPA-REG OUTCOME), C...

journal_title：Diabetes care

authors： Shao H,Shi L,Fonseca VA

更新日期：2020-07-01 00:00:00

abstract：OBJECTIVE:In type 1 diabetes (T1D), the course of microalbuminuria is unpredictable and timing of glomerular filtration rate (GFR) loss is uncertain. Thus, there is a need to identify the risk factors associated with the development of more advanced stages of kidney disease through large, long-term systematic analysis....

journal_title：Diabetes care

authors： Perkins BA,Bebu I,de Boer IH,Molitch M,Tamborlane W,Lorenzi G,Herman W,White NH,Pop-Busui R,Paterson AD,Orchard T,Cowie C,Lachin JM,Diabetes Control and Complications Trial (DCCT)\/Epidemiology of Diabetes Interventions and Com

更新日期：2019-05-01 00:00:00

abstract：OBJECTIVE:Growth deferentiation factor-15 (GDF-15) is involved in inflammation and apoptosis. Expression is induced in the heart in response to ischemia and in atherosclerotic plaques. The aim of this study was to investigate GDF-15 levels in relation to all-cause mortality, cardiovascular mortality and morbidity, decl...

journal_title：Diabetes care

authors： Lajer M,Jorsal A,Tarnow L,Parving HH,Rossing P

更新日期：2010-07-01 00:00:00

abstract：OBJECTIVE:To study the effects of mental stress on the absorption kinetics of insulin and on glucose homeostasis and lipolysis in insulin-dependent diabetes mellitus (IDDM). RESEARCH DESIGN AND METHODS:Nine IDDM patients were exposed to the Stroop color word conflict test (CWT) during 40 min after injection of 125I-la...

journal_title：Diabetes care

authors： Fernqvist-Forbes E,Linde B

更新日期：1991-11-01 00:00:00

abstract：OBJECTIVE:To evaluate the feasibility of day and night closed-loop insulin delivery in adults with type 1 diabetes under free-living conditions. RESEARCH DESIGN AND METHODS:Seventeen adults with type 1 diabetes on insulin pump therapy (means ± SD age 34 ± 9 years, HbA1c 7.6 ± 0.8%, and duration of diabetes 19 ± 9 year...

journal_title：Diabetes care

authors： Leelarathna L,Dellweg S,Mader JK,Allen JM,Benesch C,Doll W,Ellmerer M,Hartnell S,Heinemann L,Kojzar H,Michalewski L,Nodale M,Thabit H,Wilinska ME,Pieber TR,Arnolds S,Evans ML,Hovorka R,AP@home Consortium.

更新日期：2014-07-01 00:00:00

abstract：OBJECTIVE:We aimed to determine optimal blood pressure (BP) thresholds for minimizing coronary artery disease (CAD) risk in people with childhood-onset type 1 diabetes. RESEARCH DESIGN AND METHODS:The Pittsburgh Epidemiology of Diabetes Complications (EDC) Study participants without known CAD at baseline (n = 605) wer...

journal_title：Diabetes care

authors： Guo J,Brooks MM,Muldoon MF,Naimi AI,Orchard TJ,Costacou T

更新日期：2019-09-01 00:00:00

abstract：OBJECTIVE:To compare platelet plasminogen activator inhibitor 1 (PAI-1) release in type II diabetic patients and healthy control subjects. RESEARCH DESIGN AND METHODS:We studied a group of 27 diabetic patients and a group of 16 nondiabetic control subjects. Whole-blood platelet aggregation, defined as a decrease in pl...

journal_title：Diabetes care

authors： Jokl R,Klein RL,Lopes-Virella MF,Colwell JA

更新日期：1995-08-01 00:00:00

abstract：OBJECTIVE:The levels of the surrogate markers of cholesterol absorption (cholestanol and plant sterols) and synthesis (cholesterol precursors) in serum have suggested that in adult type 1 diabetes, cholesterol absorption is high and synthesis is low compared with type 2 diabetic or control subjects. Accordingly, these ...

journal_title：Diabetes care

authors： Järvisalo M,Raitakari O,Gylling H,Miettinen TA

更新日期：2006-10-01 00:00:00

abstract：OBJECTIVE:Although the Diabetes Prevention Program (DPP) and the Finnish Diabetes Prevention Study (FDPS) demonstrated that weight loss from lifestyle change reduces type 2 diabetes incidence in patients with prediabetes, the translation into community settings has been difficult. The objective of this study is to repo...

journal_title：Diabetes care

authors： Katula JA,Vitolins MZ,Rosenberger EL,Blackwell CS,Morgan TM,Lawlor MS,Goff DC Jr

更新日期：2011-07-01 00:00:00

abstract：OBJECTIVE:The role of fibrosis in early progressive renal decline in type 2 diabetes is unknown. Circulating WFDC2 (WAP four-disulfide core domain protein 2) and matrix metalloproteinase 7 (MMP-7; Matrilysin) are postulated to be biomarkers of renal fibrosis. This study examined an association of circulating levels of ...

journal_title：Diabetes care

authors： Ihara K,Skupien J,Kobayashi H,Md Dom ZI,Wilson JM,O'Neil K,Badger HS,Bowsman LM,Satake E,Breyer MD,Duffin KL,Krolewski AS

更新日期：2020-11-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to compare the University of Texas (UT) and Site, Ischemia, Neuropathy, Bacterial Infection, and Depth (SINBAD) foot ulcer scores in predicting ulcer outcome within a routine diabetes foot clinic. RESEARCH DESIGN AND METHODS:From 2006 to 2018, data were collected from all patients a...

journal_title：Diabetes care

authors： Leese GP,Soto-Pedre E,Schofield C

更新日期：2021-02-01 00:00:00

abstract：OBJECTIVE:In observational studies, low vitamin D levels are associated with type 2 diabetes (T2D), impaired glucose metabolism, insulin sensitivity, and insulin secretion. We evaluated the efficacy of vitamin D supplementation on insulin sensitivity and insulin secretion in subjects with T2D and low vitamin D (25-hydr...

journal_title：Diabetes care

authors： Gulseth HL,Wium C,Angel K,Eriksen EF,Birkeland KI

更新日期：2017-07-01 00:00:00

abstract：OBJECTIVE:It is known that continuous glucose monitoring (CGM) systems can lower mean glucose compared with episodic self-monitoring of blood glucose. Implantable CGM systems may provide additional benefits. RESEARCH DESIGN AND METHODS:We studied the Eversense (Senseonics Inc.) implantable CGM sensor in 71 participant...

journal_title：Diabetes care

authors： Kropff J,Choudhary P,Neupane S,Barnard K,Bain SC,Kapitza C,Forst T,Link M,Dehennis A,DeVries JH

更新日期：2017-01-01 00:00:00

abstract：OBJECTIVE:Transient neonatal diabetes mellitus 1 (TNDM1) is the most common cause of diabetes presenting at birth. Approximately 5% of the cases are due to recessive ZFP57 mutations, causing hypomethylation at the TNDM locus and other imprinted loci (HIL). This has consequences for patient care because it has impact on...

journal_title：Diabetes care

authors： Boonen SE,Mackay DJ,Hahnemann JM,Docherty L,Grønskov K,Lehmann A,Larsen LG,Haemers AP,Kockaerts Y,Dooms L,Vu DC,Ngoc CT,Nguyen PB,Kordonouri O,Sundberg F,Dayanikli P,Puthi V,Acerini C,Massoud AF,Tümer Z,Temple IK

更新日期：2013-03-01 00:00:00

abstract：OBJECTIVE:Therapies with metformin, sulfonylureas, or insulin improve glycemic control in the short term but do not prevent progressive islet beta-cell failure or long-term deterioration in glycemia. Our goal was to evaluate, in patients recently diagnosed with type 2 diabetes (<3 years), the long-term efficacy of mono...

journal_title：Diabetes care

authors： Viberti G,Kahn SE,Greene DA,Herman WH,Zinman B,Holman RR,Haffner SM,Levy D,Lachin JM,Berry RA,Heise MA,Jones NP,Freed MI

更新日期：2002-10-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to identify predictors of the onset of disturbed eating behavior (DEB) in adolescent girls with type 1 diabetes. RESEARCH DESIGN AND METHODS:In this prospective study, participants completed the Children's Eating Disorder Examination interview and self-report measures at baselin...

journal_title：Diabetes care

authors： Olmsted MP,Colton PA,Daneman D,Rydall AC,Rodin GM

更新日期：2008-10-01 00:00:00

abstract：:Coronary heart disease is the leading cause of death among patients with non-insulin-dependent diabetes mellitus (NIDDM). NIDDM patients have a high frequency of dyslipidemia, which along with obesity, hypertension, and hyperglycemia may contribute significantly to accelerated coronary atherosclerosis. Because risk fa...

journal_title：Diabetes care

authors： Garg A,Grundy SM

更新日期：1990-02-01 00:00:00

abstract：OBJECTIVE:Strict glycemic control in people with insulin-dependent diabetes mellitus (IDDM) reduces the risk of microvascular complications, but improvements in control are also associated with weight gain. Fears about the mortality risks of obesity may limit the acceptability of tight control. Therefore, we examined m...

journal_title：Diabetes care

authors： Chaturvedi N,Stevens LK,Fuller JH

更新日期：1995-06-01 00:00:00

abstract：OBJECTIVE:To determine on a large scale the multiple medical and nonmedical factors that influence glycemic control in the general population of children with diabetes, we performed a nationwide French cross-sectional study. RESEARCH DESIGN AND METHODS:We enrolled 2,579 patients aged 1-19 years with type 1 diabetes of...

journal_title：Diabetes care

authors： Rosilio M,Cotton JB,Wieliczko MC,Gendrault B,Carel JC,Couvaras O,Ser N,Gillet P,Soskin S,Garandeau P,Stuckens C,Le Luyer B,Jos J,Bony-Trifunovic H,Bertrand AM,Leturcq F,Lafuma A,French Pediatric Diabetes Group,Bougnèr

更新日期：1998-07-01 00:00:00

abstract：OBJECTIVE:The prevalence of type 2 diabetes is rising rapidly in low-income and middle-income countries (LMICs), but the factors driving this rapid increase are not well understood. Adult height, in particular shorter height, has been suggested to contribute to the pathophysiology and epidemiology of diabetes and may i...

journal_title：Diabetes care

authors： Teufel F,Geldsetzer P,Manne-Goehler J,Karlsson O,Koncz V,Deckert A,Theilmann M,Marcus ME,Ebert C,Seiglie JA,Agoudavi K,Andall-Brereton G,Gathecha G,Gurung MS,Guwatudde D,Houehanou C,Hwalla N,Kagaruki GB,Karki KB,Lab

更新日期：2020-10-01 00:00:00

abstract：OBJECTIVE:To test the hypothesis that intra-abdominal fat plays a primary role over general adiposity for metabolic abnormalities and atherosclerosis. RESEARCH DESIGN AND METHODS:We cross-sectionally studied 849 Japanese men aged 50.3 +/- 8.5 years (range 20-78) with BMI 23.5 +/- 2.9 kg/m(2). Intimal-medial thickness ...

journal_title：Diabetes care

authors： Takami R,Takeda N,Hayashi M,Sasaki A,Kawachi S,Yoshino K,Takami K,Nakashima K,Akai A,Yamakita N,Yasuda K

更新日期：2001-07-01 00:00:00

abstract：:The concept of gestational diabetes goes back at least to 1946. Over the years, sophistication has increased regarding the pathophysiology of this condition. However, there is not universal agreement on how to diagnose gestational diabetes. The most widely used diagnostic criteria in the U.S. were validated by their p...

journal_title：Diabetes care

authors： Coustan DR,Carpenter MW

更新日期：1998-08-01 00:00:00

abstract：OBJECTIVE:To investigate the effect of normal aging on the protective responses against hypoglycemia, in view of the fact that type II diabetes is primarily a disease of aging, and its treatment is associated with risk of hypoglycemia with cognitive impairment. RESEARCH DESIGN AND METHODS:Plasma glucose was lowered st...

journal_title：Diabetes care

authors： Matyka K,Evans M,Lomas J,Cranston I,Macdonald I,Amiel SA

更新日期：1997-02-01 00:00:00

abstract：OBJECTIVE:Regular physical activity (PA) reduces the risk of developing type 2 diabetes, and different subtypes of dysglycemia have shown different associations with PA. To better understand the associations of PA and glucose homeostasis, we examined the association of objectively measured PA energy expenditure (PAEE) ...

journal_title：Diabetes care

authors： Hansen AL,Carstensen B,Helge JW,Johansen NB,Gram B,Christiansen JS,Brage S,Lauritzen T,Jørgensen ME,Aadahl M,Witte DR,ADDITION-Denmark Steering Committee.

更新日期：2013-10-01 00:00:00

abstract：OBJECTIVE:To review the published literature and perform a meta-analysis summarizing the evidence in support of an inverse association between type 1 diabetes and the atopic disorders: asthma, eczema, and allergic rhinitis in children. RESEARCH DESIGN AND METHODS:MEDLINE, Web of Science, and PubMed were searched to id...

journal_title：Diabetes care

authors： Cardwell CR,Shields MD,Carson DJ,Patterson CC

更新日期：2003-09-01 00:00:00

abstract：:Intensive insulin therapy is best defined as a comprehensive system of diabetes management with the patient and management team as partners. The system is directed at improvement of glycemia and patient well-being. Glycemic targets should be individually defined. Frequent self-monitoring of blood glucose, probably at ...

journal_title：Diabetes care

authors： Hirsch IB,Farkas-Hirsch R,Skyler JS

更新日期：1990-12-01 00:00:00

abstract：:The affinity of human (recombinant DNA) insulin and porcine insulin to preformed IgG-insulin antibodies of insulin-treated diabetic individuals was studied in 29 insulin-treated diabetic patients. The binding of 125I-human insulin and 125I-porcine insulin with antibodies was similar in the group of patients without in...

journal_title：Diabetes care

authors： Schernthaner G

更新日期：1982-11-01 00:00:00

abstract：OBJECTIVE:Physical activity is integral to the management of type 2 diabetes. Unfortunately, the majority of adults with type 2 diabetes do not regularly engage in physical activity. The purpose of this study was to assess physical activity behavior and its correlates (i.e., physical activity knowledge, barriers, and p...

journal_title：Diabetes care

authors： Hays LM,Clark DO

更新日期：1999-05-01 00:00:00

abstract：OBJECTIVE:To test the effect of an automated system providing real-time estimates of HbA(1c), glucose variability, and risk for hypoglycemia. RESEARCH DESIGN AND METHODS:For 1 year, 120 adults with type 1 diabetes (69 female/51 male, age = 39.1 [14.3] years, duration of diabetes 20.3 [12.9] years, HbA(1c) = 8.0 [1.5])...

journal_title：Diabetes care

authors： Kovatchev BP,Mendosa P,Anderson S,Hawley JS,Ritterband LM,Gonder-Frederick L

更新日期：2011-02-01 00:00:00