Ginseng therapy in non-insulin-dependent diabetic patients.

Abstract:

OBJECTIVE:To investigate the effect of ginseng on newly diagnosed non-insulin-dependent diabetes mellitus (NIDDM) patients. RESEARCH DESIGN AND METHODS:In this double-blind placebo-controlled study, 36 NIDDM patients were treated for 8 weeks with ginseng (100 or 200 mg) or placebo. Efficacy was evaluated with psychophysical tests and measurements of glucose balance, serum lipids, aminoterminalpropeptide (PIIINP) concentration, and body weight. RESULTS:Ginseng therapy elevated mood, improved psychophysical performance, and reduced fasting blood glucose (FBG) and body weight. The 200-mg dose of ginseng improved glycated hemoglobin, serum PIIINP, and physical activity. Placebo reduced body weight and altered the serum lipid profile but did not alter FBG. CONCLUSIONS:Ginseng may be a useful therapeutic adjunct in the management of NIDDM.

journal_name

Diabetes Care

journal_title

Diabetes care

authors

Sotaniemi EA,Haapakoski E,Rautio A

doi

10.2337/diacare.18.10.1373

subject

Has Abstract

pub_date

1995-10-01 00:00:00

pages

1373-5

issue

10

eissn

0149-5992

issn

1935-5548

journal_volume

18

pub_type

临床试验,杂志文章,多中心研究
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    abstract:OBJECTIVE:The purpose of this study was to compare different outcome measures in the audit of management of diabetic foot ulcers RESEARCH DESIGN AND METHODS:Data collected prospectively in a consecutive cohort of patients referred to a specialist multidisciplinary foot care clinic between 1 January 2000 and 31 Decembe...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc06-0306

    authors: Jeffcoate WJ,Chipchase SY,Ince P,Game FL

    更新日期:2006-08-01 00:00:00

  • White matter structural differences in young children with type 1 diabetes: a diffusion tensor imaging study.

    abstract:OBJECTIVE:To detect clinical correlates of cognitive abilities and white matter (WM) microstructural changes using diffusion tensor imaging (DTI) in young children with type 1 diabetes. RESEARCH DESIGN AND METHODS:Children, ages 3 to <10 years, with type 1 diabetes (n = 22) and age- and sex-matched healthy control sub...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc12-0017

    authors: Aye T,Barnea-Goraly N,Ambler C,Hoang S,Schleifer K,Park Y,Drobny J,Wilson DM,Reiss AL,Buckingham BA

    更新日期:2012-11-01 00:00:00

  • Differential Association of Microvascular Attributions With Cardiovascular Disease in Patients With Long Duration of Type 1 Diabetes.

    abstract:OBJECTIVE:Independent association of chronic kidney disease (CKD) and proliferative diabetic retinopathy (PDR) with cardiovascular disease (CVD) has not been established. In the Joslin 50-Year Medalist study, characterizing individuals with type 1 diabetes for 50 years or more, we examined the associations of CKD and P...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc17-2250

    authors: Gordin D,Harjutsalo V,Tinsley L,Fickweiler W,Sun JK,Forsblom C,Amenta PS,Pober D,D'Eon S,Khatri M,Stillman IE,Groop PH,Keenan HA,King GL

    更新日期:2018-04-01 00:00:00

  • Adolescent Type 1 Diabetes Cardio-Renal Intervention Trial (AdDIT): urinary screening and baseline biochemical and cardiovascular assessments.

    abstract:OBJECTIVE:We assessed the association between early increases in albumin excretion and cardiovascular (CV) and renal markers in a large cohort of young people with type 1 diabetes. RESEARCH DESIGN AND METHODS:As part of preliminary screening for a multicenter, randomized controlled trial of statins/ACE inhibitors, we ...

    journal_title:Diabetes care

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.2337/dc13-1634

    authors: Marcovecchio ML,Woodside J,Jones T,Daneman D,Neil A,Prevost T,Dalton RN,Deanfield J,Dunger DB,AdDIT Investigators.

    更新日期:2014-01-01 00:00:00

  • Dose response of inhaled dry-powder insulin and dose equivalence to subcutaneous insulin lispro.

    abstract:OBJECTIVE:To determine the pharmacokinetic (PK) and glucodynamic (GD) dose response of human insulin inhalation powder (HIIP) delivered via AIR particle technology and dose equivalence to subcutaneous (SC) insulin lispro. RESEARCH DESIGN AND METHODS:Twenty healthy, nonsmoking, male or female subjects (aged 29.6 +/- 6....

    journal_title:Diabetes care

    pub_type: 杂志文章,随机对照试验

    doi:10.2337/diacare.28.10.2400

    authors: Rave KM,Nosek L,de la Peña A,Seger M,Ernest CS 2nd,Heinemann L,Batycky RP,Muchmore DB

    更新日期:2005-10-01 00:00:00

  • Dairy consumption and the incidence of hyperglycemia and the metabolic syndrome: results from a french prospective study, Data from the Epidemiological Study on the Insulin Resistance Syndrome (DESIR).

    abstract:OBJECTIVE:In the French Data from the Epidemiological Study on the Insulin Resistance Syndrome (DESIR) cohort, cross-sectional analyses have shown that a higher consumption of dairy products and calcium are associated with a lower prevalence of the metabolic syndrome (MetS). We assess the influence of dairy products on...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc10-1772

    authors: Fumeron F,Lamri A,Abi Khalil C,Jaziri R,Porchay-Baldérelli I,Lantieri O,Vol S,Balkau B,Marre M,Data from the Epidemiological Study on the Insulin Resistance Syndrome (DESIR) Study Group.

    更新日期:2011-04-01 00:00:00

  • Diabetes in America: epidemiology and scope of the problem.

    abstract::Epidemiological studies performed over the past 40 years have shown that the prevalence of diagnosed diabetes has increased dramatically in the U.S. and that a substantial proportion of the population has undiagnosed diabetes, impaired fasting glucose, and impaired glucose tolerance. Diabetes is most prevalent in mino...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.21.3.c11

    authors: Harris MI

    更新日期:1998-12-01 00:00:00

  • Risk Factors for Kidney Disease in Type 1 Diabetes.

    abstract:OBJECTIVE:In type 1 diabetes (T1D), the course of microalbuminuria is unpredictable and timing of glomerular filtration rate (GFR) loss is uncertain. Thus, there is a need to identify the risk factors associated with the development of more advanced stages of kidney disease through large, long-term systematic analysis....

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc18-2062

    authors: Perkins BA,Bebu I,de Boer IH,Molitch M,Tamborlane W,Lorenzi G,Herman W,White NH,Pop-Busui R,Paterson AD,Orchard T,Cowie C,Lachin JM,Diabetes Control and Complications Trial (DCCT)\/Epidemiology of Diabetes Interventions and Com

    更新日期:2019-05-01 00:00:00

  • Type 2 Diabetes in Relation to the Risk of Renal Cell Carcinoma Among Men and Women in Two Large Prospective Cohort Studies.

    abstract:OBJECTIVE:We assessed whether type 2 diabetes is associated with renal cell carcinoma (RCC), independent of key potential confounders, in two large prospective cohorts with biennially updated covariate data. RESEARCH DESIGN AND METHODS:A total of 117,570 women from the Nurses' Health Study (NHS) and 48,866 men from th...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc17-2518

    authors: Graff RE,Sanchez A,Tobias DK,Rodríguez D,Barrisford GW,Blute ML,Li Y,Sun Q,Preston MA,Wilson KM,Cho E

    更新日期:2018-07-01 00:00:00

  • Effect of protein ingestion on the glucose and insulin response to a standardized oral glucose load.

    abstract::Type II diabetic subjects were given 50 g protein, 50 g glucose, or 50 g glucose with 50 g protein as a single meal in random sequence. The plasma glucose and insulin response was determined over the subsequent 5 h. The plasma glucose area above the baseline following a glucose meal was reduced 34% when protein was gi...

    journal_title:Diabetes care

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.2337/diacare.7.5.465

    authors: Nuttall FQ,Mooradian AD,Gannon MC,Billington C,Krezowski P

    更新日期:1984-09-01 00:00:00

  • Discordance in perceptions of barriers to diabetes care between patients and primary care and secondary care.

    abstract:OBJECTIVE:We sought to compare perceived barriers to diabetes care between people with diabetes and different health professional groups. RESEARCH DESIGN AND METHODS:This was a cross-sectional, postal, open-questionnaire survey conducted in the Waikato district, New Zealand. A total of 3,890 individuals with diabetes ...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc06-2338

    authors: Simmons D,Lillis S,Swan J,Haar J

    更新日期:2007-03-01 00:00:00

  • Intensive replacement of basal insulin in patients with type 1 diabetes given rapid-acting insulin analog at mealtime: a 3-month comparison between administration of NPH insulin four times daily and glargine insulin at dinner or bedtime.

    abstract:OBJECTIVE:To establish differences in blood glucose between different regimens of optimized basal insulin substitution in type 1 diabetic patients given lispro insulin at meals, i.e., NPH injected four times a day versus glargine insulin once daily at dinner or at bedtime. RESEARCH DESIGN AND METHODS:A total of 51 pat...

    journal_title:Diabetes care

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.2337/diacare.26.5.1490

    authors: Rossetti P,Pampanelli S,Fanelli C,Porcellati F,Costa E,Torlone E,Scionti L,Bolli GB

    更新日期:2003-05-01 00:00:00

  • Combined use of fasting plasma glucose and HbA1c predicts the progression to diabetes in Chinese subjects.

    abstract:OBJECTIVE:We have previously suggested using the paired values of fasting plasma glucose (FPG) and HbA1c to identify potential diabetic subjects. In this article, we followed up on 208 nondiabetic subjects and examined their rates of progression to diabetes. We analyzed their likelihood of becoming diabetic according t...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.23.12.1770

    authors: Ko GT,Chan JC,Tsang LW,Cockram CS

    更新日期:2000-12-01 00:00:00

  • Increasing the accuracy of oral glucose tolerance testing and extending its application to individuals with normal glucose tolerance for the prediction of type 1 diabetes: the Diabetes Prevention Trial-Type 1.

    abstract:OBJECTIVE:We assessed the extent to which both standard and alternative indexes from 2-h oral glucose tolerance testing predict type 1 diabetes and whether oral glucose tolerance tests (OGTTs) predict type 1 diabetes in individuals with normal glucose tolerance. RESEARCH DESIGN AND METHODS:The prediction of type 1 dia...

    journal_title:Diabetes care

    pub_type: 杂志文章,多中心研究

    doi:10.2337/dc06-1615

    authors: Sosenko JM,Palmer JP,Greenbaum CJ,Mahon J,Cowie C,Krischer JP,Chase HP,White NH,Buckingham B,Herold KC,Cuthbertson D,Skyler JS,Diabetes Prevention Trial-Type 1 Study Group.

    更新日期:2007-01-01 00:00:00

  • Genetic Tools for Coronary Risk Assessment in Type 2 Diabetes: A Cohort Study From the ACCORD Clinical Trial.

    abstract:OBJECTIVE:We evaluated whether the increasing number of genetic loci for coronary artery disease (CAD) identified in the general population could be used to predict the risk of major CAD events (MCE) among participants with type 2 diabetes at high cardiovascular risk. RESEARCH DESIGN AND METHODS:A weighted genetic ris...

    journal_title:Diabetes care

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.2337/dc18-0709

    authors: Morieri ML,Gao H,Pigeyre M,Shah HS,Sjaarda J,Mendonca C,Hastings T,Buranasupkajorn P,Motsinger-Reif AA,Rotroff DM,Sigal RJ,Marcovina SM,Kraft P,Buse JB,Wagner MJ,Gerstein HC,Mychaleckyj JC,Parè G,Doria A

    更新日期:2018-11-01 00:00:00

  • Effects of dapagliflozin, an SGLT2 inhibitor, on HbA(1c), body weight, and hypoglycemia risk in patients with type 2 diabetes inadequately controlled on pioglitazone monotherapy.

    abstract:OBJECTIVE:To examine the safety and efficacy of dapagliflozin, a sodium-glucose cotransporter-2 inhibitor, added on to pioglitazone in type 2 diabetes inadequately controlled on pioglitazone. RESEARCH DESIGN AND METHODS:Treatment-naive patients or those receiving metformin, sulfonylurea, or thiazolidinedione entered a...

    journal_title:Diabetes care

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.2337/dc11-1693

    authors: Rosenstock J,Vico M,Wei L,Salsali A,List JF

    更新日期:2012-07-01 00:00:00

  • Insufficient control of blood pressure and incident diabetes.

    abstract:OBJECTIVE:Incidence of type 2 diabetes might be associated with preexisting hypertension. There is no information on whether incident diabetes is predicted by blood pressure control. We evaluated the hazard of diabetes in relation to blood pressure control in treated hypertensive patients. RESEARCH DESIGN AND METHODS:...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc08-1881

    authors: Izzo R,de Simone G,Chinali M,Iaccarino G,Trimarco V,Rozza F,Giudice R,Trimarco B,De Luca N

    更新日期:2009-05-01 00:00:00

  • The clinical pharmacology of human insulin (Novo) in normal subjects.

    abstract::Neutral regular human insulin (Novo) (derived from porcine insulin) and porcine insulin were administered by subcutaneous (s.c.) injection into the anterior abdominal wall in two different groups of six normal male subjects. The insulin dosage was 0.075 IU/kg body wt; diluting medium was used to obtain control values....

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:

    authors: Owens DR,Jones MK,Birtwell AJ,Jones IR,Hayes TM,Heding LG

    更新日期:1983-03-01 00:00:00

  • Markers of insulin resistance are strong risk factors for retinopathy incidence in type 1 diabetes.

    abstract:OBJECTIVE:To determine the incidence of retinopathy and the relative importance of its risk factors in type 1 diabetes. RESEARCH DESIGN AND METHODS:This is a 7.3-year follow-up of 764 of 1,215 (63%) people with type 1 diabetes across Europe, aged 15-60 years at baseline with no retinopathy (the EURODIAB Prospective Co...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.24.2.284

    authors: Chaturvedi N,Sjoelie AK,Porta M,Aldington SJ,Fuller JH,Songini M,Kohner EM,EURODIAB Prospective Complications Study.

    更新日期:2001-02-01 00:00:00

  • Fetal hemoglobin in diabetic patients.

    abstract:OBJECTIVE:To determine the occurrence of elevated fetal hemoglobin (HbF) among the diabetic population and determine the clinical situation of importance. RESEARCH DESIGN AND METHODS:A cross-sectional study was conducted. HbA1c and HbF were measured with high-performance liquid chromatography in 1,104 consecutive diab...

    journal_title:Diabetes care

    pub_type: 临床试验,杂志文章

    doi:10.2337/diacare.17.8.828

    authors: Koskinen LK,Lahtela JT,Koivula TA

    更新日期:1994-08-01 00:00:00

  • Glycemic control in early IDDM. The Wisconsin Diabetes Registry.

    abstract:OBJECTIVE:A cohort (n = 277) was followed from diabetes diagnosis to evaluate longitudinal glycemic control, urinary C-peptide levels, and certain features of diabetes self-management. RESEARCH DESIGN AND METHODS:Unselected cases with IDDM, who were less than 30 yr of age, were identified at diagnosis from a 28-county...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.15.8.980

    authors: Allen C,Zaccaro DJ,Palta M,Klein R,Duck SC,D'Alessio DJ

    更新日期:1992-08-01 00:00:00

  • Distortion-product otoacoustic emissions and selective sensorineural loss in IDDM.

    abstract:OBJECTIVE:To provide information about possible subclinical damage of the cochlear outer hair cells (OHCs) by means of transiently evoked otoacoustic emissions (TEOAEs) and distortion-product otoacoustic emissions (DPOAEs) in subjects with IDDM. RESEARCH DESIGN AND METHODS:TEOAEs and DPOAEs were recorded in 47 IDDM pa...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.21.8.1317

    authors: Di Nardo W,Ghirlanda G,Paludetti G,Cercone S,Saponara C,Del Ninno M,Di Girolamo S,Magnani P,Di Leo MA

    更新日期:1998-08-01 00:00:00

  • Use of Sodium-Glucose Cotransporter 2 Inhibitors in Patients With Type 1 Diabetes and Rates of Diabetic Ketoacidosis.

    abstract:OBJECTIVE:To estimate real-world off-label use of sodium-glucose cotransporter 2 (SGLT2) inhibitors in patients with type 1 diabetes, estimate rates of diabetic ketoacidosis (DKA), and compare them with DKA rates observed in sotagliflozin clinical trials. RESEARCH DESIGN AND METHODS:We identified initiators of SGLT2 i...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc19-1481

    authors: Hampp C,Swain RS,Horgan C,Dee E,Qiang Y,Dutcher SK,Petrone A,Chen Tilney R,Maro JC,Panozzo CA

    更新日期:2020-01-01 00:00:00

  • Total plasma antioxidant capacity predicts thrombosis-prone status in NIDDM patients.

    abstract:OBJECTIVE:To explore the hypothesis that a relationship exists between free radical activity and abnormalities in hemostasis in NIDDM. RESEARCH DESIGN AND METHODS:The use of the total radical-trapping antioxidant parameter (TRAP) has very recently been proposed to explore the antioxidant property of a plasma and their...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.20.10.1589

    authors: Ceriello A,Bortolotti N,Pirisi M,Crescentini A,Tonutti L,Motz E,Russo A,Giacomello R,Stel G,Taboga C

    更新日期:1997-10-01 00:00:00

  • The epidemiology of diabetes in pregnant Native Canadians. A risk profile.

    abstract:OBJECTIVE:The purpose of this study was to determine the prevalence of diabetes in pregnancy (gestational diabetes mellitus [GDM] and NIDDM) and to identify risk factors in the development of GDM in a native population in northwestern Ontario, Canada. RESEARCH DESIGN AND METHODS:A retrospective analysis of 1,305 singl...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.20.9.1422

    authors: Harris SB,Caulfield LE,Sugamori ME,Whalen EA,Henning B

    更新日期:1997-09-01 00:00:00

  • Concordance for type 1 diabetes in identical twins is affected by insulin genotype.

    abstract:OBJECTIVE:Monozygotic twins are usually discordant (only one twin affected) for type 1 diabetes. Discordance for disease between such twins implies a role for nongenetically determined factors but could also be influenced by a decreased load of diabetes susceptibility genes. The aim of this study was to determine wheth...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.24.5.838

    authors: Metcalfe KA,Hitman GA,Rowe RE,Hawa M,Huang X,Stewart T,Leslie RD

    更新日期:2001-05-01 00:00:00

  • Increased urinary endothelin-1-like immunoreactivity excretion in NIDDM patients with albuminuria.

    abstract:OBJECTIVE:To determine the urinary endothelin-1-like immunoreactivity (ET-1-LI) in non-insulin-dependent diabetes mellitus (NIDDM) patients and to investigate whether urinary ET-1-LI excretion is elevated in patients with albuminuria. RESEARCH DESIGN AND METHODS:Urinary ET-1-LI substance was determined by radioimmunoa...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.17.4.263

    authors: Lee YJ,Shin SJ,Tsai JH

    更新日期:1994-04-01 00:00:00

  • Cerebral and ophthalmic artery hemodynamic responses in diabetes mellitus.

    abstract:OBJECTIVE:To address whether hemodynamic responses in the cerebral arteries and OAs may be altered in patients with diabetic retinopathy. We used TCD to evaluate the effects of changes in BP, posture, and exercise on MCA and OA blood flow velocities. RESEARCH DESIGN AND METHODS:We evaluated 13 patients with BDR, 19 wi...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.16.2.476

    authors: Albert SG,Gomez CR,Russell S,Chaitman BR,Bernbaum M,Kong BA

    更新日期:1993-02-01 00:00:00

  • Additional lunchtime basal insulin during insulin lispro intensive therapy in a randomized, multicenter, crossover study in adults : a real-life design.

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    journal_title:Diabetes care

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.2337/diacare.25.4.712

    authors: Stades AM,Hoekstra JB,van den Tweel I,Erkelens DW,Holleman F,STABILITY Study Group.

    更新日期:2002-04-01 00:00:00

  • Skeletal muscle deoxygenation after the onset of moderate exercise suggests slowed microvascular blood flow kinetics in type 2 diabetes.

    abstract:OBJECTIVE:People with type 2 diabetes have impaired exercise responses even in the absence of cardiovascular complications. One key factor associated with the exercise intolerance is abnormally slowed oxygen uptake (VO2) kinetics during submaximal exercise. The mechanisms of this delayed adaptation during exercise are ...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc07-0843

    authors: Bauer TA,Reusch JE,Levi M,Regensteiner JG

    更新日期:2007-11-01 00:00:00