Use of Sodium-Glucose Cotransporter 2 Inhibitors in Patients With Type 1 Diabetes and Rates of Diabetic Ketoacidosis.

abstract：OBJECTIVE:Screening involves the presumptive identification of asymptomatic individuals at increased risk for unrecognized disease. We examined changes in screening practices for prediabetes and diabetes since January 2010, when HbA1c was first recommended as an option for screening and diagnosis. RESEARCH DESIGN AND ...

journal_title：Diabetes care

authors： Evron JM,Herman WH,McEwen LN

更新日期：2019-04-01 00:00:00

abstract：OBJECTIVE:This study compared diabetes Treatment As Usual (TAU) with Pathways To Change (PTC), an intervention developed from the Transtheoretical Model of Change (TTM), to determine whether the PTC intervention would result in greater readiness to change, greater increases in self-care, and improved diabetes control. ...

journal_title：Diabetes care

authors： Jones H,Edwards L,Vallis TM,Ruggiero L,Rossi SR,Rossi JS,Greene G,Prochaska JO,Zinman B,Diabetes Stages of Change (DiSC) Study.

更新日期：2003-03-01 00:00:00

abstract：OBJECTIVE:Whether ACE inhibition is useful for type 2 diabetic patients with micro- and macroalbuminuria remains unknown. The Non-Insulin-Dependent Diabetes, Hypertension, Microalbuminuria, Cardiovascular Events and Ramipril (DIABHYCAR) Study was set up to address this issue through a multicenter double-blind parallel ...

journal_title：Diabetes care

authors： Marre M,Lièvre M,Vasmant D,Gallois Y,Hadjadj S,Reglier JC,Chatellier G,Mann J,Viberti GC,Passa P

更新日期：2000-04-01 00:00:00

abstract：OBJECTIVE:The relative roles of insulin resistance and beta-cell dysfunction in the pathogenesis of impaired glucose tolerance (IGT) and type 2 diabetes are debated. First-degree relatives of individuals with type 2 diabetes are at increased risk of developing hyperglycemia. RESEARCH DESIGN AND METHODS:We evaluated th...

journal_title：Diabetes care

authors： Cnop M,Vidal J,Hull RL,Utzschneider KM,Carr DB,Schraw T,Scherer PE,Boyko EJ,Fujimoto WY,Kahn SE

更新日期：2007-03-01 00:00:00

abstract：:OBJECTIVE To examine the efficacy and safety of rimonabant, a selective cannabinoid receptor type-1 antagonist, in patients with type 2 diabetes receiving insulin monotherapy. RESEARCH DESIGN AND METHODS Patients (n = 368; A1C > or =7%) were randomized to 20 mg/day rimonabant or placebo in this 48-week, double-blind, ...

journal_title：Diabetes care

authors： Hollander PA,Amod A,Litwak LE,Chaudhari U,ARPEGGIO Study Group.

更新日期：2010-03-01 00:00:00

abstract：OBJECTIVE:To summarize the frequency of physician adherence to consensus recommendations for prevention of diabetic complications. RESEARCH DESIGN AND METHODS:Survey data from a nationwide stratified probability sample of primary-care physicians were analyzed. Adherence to recommendations were reported by physician sp...

journal_title：Diabetes care

authors： Kenny SJ,Smith PJ,Goldschmid MG,Newman JM,Herman WH

更新日期：1993-11-01 00:00:00

abstract：OBJECTIVE:N-acetylglucosamine/galactosamine (GlycA) and sialic acid (GlycB) moieties of glycosylated serum proteins are nonspecific measures of inflammation, but conclusive data on their relationship with insulin resistance or insulin secretion are missing. Therefore, we aimed to examine the relation of GlycA, GlycB, a...

journal_title：Diabetes care

authors： Lorenzo C,Festa A,Hanley AJ,Rewers MJ,Escalante A,Haffner SM

更新日期：2017-03-01 00:00:00

abstract：:We measured hemoglobin A1 (HbA1) and performed clean-catch urine cultures in 752 patients (411 men and 341 women) with non-insulin-dependent diabetes mellitus (NIDDM) attending an outpatient diabetes clinic. Prevalence of bacteriuria was significantly greater in diabetic women than in controls (9.1 vs. 5.0%, P less th...

journal_title：Diabetes care

authors： Schmitt JK,Fawcett CJ,Gullickson G

更新日期：1986-09-01 00:00:00

abstract：OBJECTIVE:To estimate incidence rates of diabetes and associated risk factors among participants of the Strong Heart Study. RESEARCH DESIGN AND METHODS:Of the 4,549 Strong Heart Study participants examined at baseline, 3,638 returned for a similar examination after an average of 4 years. The 1985 World Health Organiza...

journal_title：Diabetes care

authors： Lee ET,Welty TK,Cowan LD,Wang W,Rhoades DA,Devereux R,Go O,Fabsitz R,Howard BV

更新日期：2002-01-01 00:00:00

abstract：OBJECTIVE:In children with type 1 diabetes (T1D), severe hypoglycemia (SH) is associated with poorer cognition, but the association of SH with cognitive function in late life is unknown. Given the increasing life expectancy in people with T1D, understanding the role of SH in brain health is crucial. RESEARCH DESIGN AN...

journal_title：Diabetes care

authors： Lacy ME,Gilsanz P,Eng C,Beeri MS,Karter AJ,Whitmer RA

更新日期：2020-03-01 00:00:00

abstract：:The association of obesity with hypertension has been amply demonstrated in cross-sectional, longitudinal, and dietary-intervention studies, but the mechanisms remain enigmatic. Both conditions are independently characterized by similar metabolic alterations, i.e., glucose intolerance, dyslipoproteinemia, elevated ser...

journal_title：Diabetes care

authors： Modan M,Halkin H

更新日期：1991-06-01 00:00:00

abstract：:In past studies on the psychological aspects of diabetes mellitus, symptoms of depression have been identified as the most common manifestation among diabetic patients. Other psychological manifestations have been anxiety, hypochondriasis, increased dependence and passivity, and poor self-image. Ten insulin-dependent ...

journal_title：Diabetes care

authors： Dupuis A

更新日期：1980-01-01 00:00:00

abstract：:Cyclosporin and other immunosuppressive agents have been proposed as a preventive treatment against the development of insulin-dependent diabetes mellitus (IDDM) in relatives at increased risk for the disease, based on the understanding that its etiology is an ongoing process of autoimmune beta-cell destruction. We us...

journal_title：Diabetes care

authors： Lipton R,LaPorte RE,Becker DJ,Dorman JS,Orchard TJ,Atchison J,Drash AL

更新日期：1990-07-01 00:00:00

abstract：:Pregnancy induces complex changes in energy metabolism, manifested clinically by insulin resistance, low fasting blood glucose levels, and proneness to ketosis. It is quite unusual for pregnant women who do not have type I diabetes to progress from ketosis to frank ketoacidosis, although this phenomenon is common in l...

journal_title：Diabetes care

authors： Bedalov A,Balasubramanyam A

更新日期：1997-06-01 00:00:00

abstract：OBJECTIVE:The role of general practice and diabetes clinics in the management of diabetes is still a matter of debate. Methodological flaws in previous studies may have led to inaccurate conclusions when comparing the care provided in these different settings. We compared the care provided to type 2 diabetic patients a...

journal_title：Diabetes care

authors： De Berardis G,Pellegrini F,Franciosi M,Belfiglio M,Di Nardo B,Greenfield S,Kaplan SH,Rossi MC,Sacco M,Tognoni G,Valentini M,Nicolucci A,QuED Study.

更新日期：2004-02-01 00:00:00

abstract：OBJECTIVE:To assess the impact of hyperglycemia in different age-groups of patients with acute myocardial infarction (AMI). RESEARCH DESIGN AND METHODS:A total of 2,027 patients with AMI were categorized into one of five age-groups: <50 years (n = 301), ≥50 and <60 (n = 477), ≥60 and <70 (n = 545), ≥70 and <80 (n = 49...

journal_title：Diabetes care

authors： Nicolau JC,Serrano CV Jr,Giraldez RR,Baracioli LM,Moreira HG,Lima F,Franken M,Kalil R,Ramires JA,Giugliano RP

更新日期：2012-01-01 00:00:00

abstract：OBJECTIVE:To examine the association of stage of change with diet and exercise behaviors in response to a lifestyle intervention for Native Hawaiians (NHs). RESEARCH DESIGN AND METHODS:A family ('ohana) support lifestyle intervention was compared with a standard intervention in NHs with or at risk for diabetes in two ...

journal_title：Diabetes care

authors： Mau MK,Glanz K,Severino R,Grove JS,Johnson B,Curb JD

更新日期：2001-10-01 00:00:00

abstract：OBJECTIVE:To create a simple prediction rule that could perform as well as the 2-h postchallenge plasma glucose (PCPG) test to predict those at risk for diabetes. We created a prediction rule in one sample and prospectively validated it for incident diabetes in a separate cohort. RESEARCH DESIGN AND METHODS:A cross-se...

journal_title：Diabetes care

authors： Kanaya AM,Wassel Fyr CL,de Rekeneire N,Shorr RI,Schwartz AV,Goodpaster BH,Newman AB,Harris T,Barrett-Connor E

更新日期：2005-02-01 00:00:00

abstract：OBJECTIVE:To examine the comparative effectiveness of the sodium-glucose cotransporter 2 inhibitor (SGLT2i) empagliflozin and other non-SGLT2i antihyperglycemics on the risk of major adverse kidney events (MAKE) of estimated glomerular filtration rate (eGFR) decline >50%, end-stage kidney disease, or all-cause mortalit...

journal_title：Diabetes care

authors： Xie Y,Bowe B,Gibson AK,McGill JB,Yan Y,Maddukuri G,Al-Aly Z

更新日期：2020-11-01 00:00:00

abstract：OBJECTIVE:Advanced glycation end products (AGEs) are a risk factor for diabetic complications. We have developed an assay method for N-(carboxymethyl)valine (CMV) of the hemoglobin (CMV-Hb), which is an AGE generated from HbA1c. Herein we describe the clinical utility of CMV-Hb measurement for the diagnosis of diabetic...

journal_title：Diabetes care

authors： Uchimura T,Nakano K,Hashiguchi T,Iwamoto H,Miura K,Yoshimura Y,Hanyu N,Hirata K,Imakuma M,Motomiya Y,Maruyama I

更新日期：2001-05-01 00:00:00

abstract：OBJECTIVE:Diabetes surveillance often requires manual medical chart reviews to confirm status and type. This project aimed to create an electronic health record (EHR)-based procedure for improving surveillance efficiency through automation of case identification. RESEARCH DESIGN AND METHODS:Youth (<20 years old) with ...

journal_title：Diabetes care

authors： Wells BJ,Lenoir KM,Wagenknecht LE,Mayer-Davis EJ,Lawrence JM,Dabelea D,Pihoker C,Saydah S,Casanova R,Turley C,Liese AD,Standiford D,Kahn MG,Hamman R,Divers J

更新日期：2020-10-01 00:00:00

abstract：OBJECTIVE:Impaired muscular mitochondrial function is related to common insulin resistance in type 2 diabetes. Mitochondrial diseases frequently lead to diabetes, which is mostly attributed to defective beta-cell mitochondria and secretion. RESEARCH DESIGN AND METHODS:We assessed muscular mitochondrial function and li...

journal_title：Diabetes care

authors： Szendroedi J,Schmid AI,Meyerspeer M,Cervin C,Kacerovsky M,Smekal G,Gräser-Lang S,Groop L,Roden M

更新日期：2009-04-01 00:00:00

abstract：OBJECTIVE:To investigate the effects of metformin on glycemic control, insulin resistance, and risk factors for cardiovascular disease in NIDDM subjects from two ethnic groups (Caucasian and Asian) with different risks of cardiovascular disease. RESEARCH DESIGN AND METHODS:A total of 27 subjects with NIDDM (17 Caucasi...

journal_title：Diabetes care

authors： Nagi DK,Yudkin JS

更新日期：1993-04-01 00:00:00

abstract：OBJECTIVE:In patients with type 2 diabetes and cardiovascular diseases (CVDs), intensive treatment with insulin and/or sulfonylurea (SU) may be associated with excessive increased risk of hypoglycemic episodes. To evaluate the risk of critical arrhythmias related to glycemic variability, we carried out an observational...

journal_title：Diabetes care

authors： Stahn A,Pistrosch F,Ganz X,Teige M,Koehler C,Bornstein S,Hanefeld M

更新日期：2014-02-01 00:00:00

abstract：OBJECTIVE:To assess the effects of empagliflozin, a selective sodium-glucose cotransporter 2 (SGLT2) inhibitor, on broad biological systems through proteomics. RESEARCH DESIGN AND METHODS:Aptamer-based proteomics was used to quantify 3,713 proteins in 144 paired plasma samples obtained from 72 participants across the ...

journal_title：Diabetes care

authors： Ferrannini E,Murthy AC,Lee YH,Muscelli E,Weiss S,Ostroff RM,Sattar N,Williams SA,Ganz P

更新日期：2020-09-01 00:00:00

abstract：OBJECTIVE:Progressive nephropathy represents a substantial source of morbidity and mortality in type 1 diabetes. Increasing albuminuria is a strong predictor of progressive renal dysfunction and heightened cardiovascular risk. Early albuminuria probably reflects vascular endothelial dysfunction, which may be mediated i...

journal_title：Diabetes care

authors： Lin J,Glynn RJ,Rifai N,Manson JE,Ridker PM,Nathan DM,Schaumberg DA

更新日期：2008-12-01 00:00:00

abstract：OBJECTIVE:To examine the evolution of the dysregulated glucagon responses to mixed-meal tolerance tests (MMTTs) in youth with recent-onset type 1 diabetes (T1D). RESEARCH DESIGN AND METHODS:MMTTs were performed in 25 youth (9-18 years of age) with 1.5-12 months disease duration (year 1); 22 subjects were restudied 1 y...

journal_title：Diabetes care

authors： Sherr J,Tsalikian E,Fox L,Buckingham B,Weinzimer S,Tamborlane WV,White NH,Arbelaez AM,Kollman C,Ruedy KJ,Cheng P,Beck RW,Diabetes Research in Children Network.

更新日期：2014-06-01 00:00:00

abstract：OBJECTIVE:The current study aimed to determine in the Diabetes Control and Complications Trial (DCCT)/Epidemiology of Diabetes Interventions and Complications cohort whether or not abnormal levels of markers of inflammation and endothelial dysfunction measured in samples collected at DCCT baseline were able to predict ...

journal_title：Diabetes care

authors： Lopes-Virella MF,Baker NL,Hunt KJ,Cleary PA,Klein R,Virella G,DCCT\/EDIC Research Group.

更新日期：2013-08-01 00:00:00

abstract：OBJECTIVE:To explore the possible link between diabetic nephropathy and the enhanced activity of the polyol pathway, known to occur in IDDM subjects. RESEARCH DESIGN AND METHODS:We studied the effects of the aldose reductase inhibitor tolrestat (200 mg/day) on urinary albumin excretion rate and glomerular filtration r...

journal_title：Diabetes care

authors： Passariello N,Sepe J,Marrazzo G,De Cicco A,Peluso A,Pisano MC,Sgambato S,Tesauro P,D'Onofrio F

更新日期：1993-05-01 00:00:00

abstract：OBJECTIVE:To determine the prevalence of IGT and diabetes and identify the occurrence of CVD and its risk factors. RESEARCH DESIGN AND METHODS:This study was a population-based, cross-sectional study of 110,660 residents, 25-74 yr of age of DaQing, Hei Long Jiang Province, China. RESULTS:Using 1985 WHO criteria, 577 ...

journal_title：Diabetes care

authors： Pan XR,Hu YH,Li GW,Liu PA,Bennett PH,Howard BV

更新日期：1993-01-01 00:00:00