Inflammation and progressive nephropathy in type 1 diabetes in the diabetes control and complications trial.

abstract：OBJECTIVE:The aim of this study was to determine whether the use of meal bolus alarms would result in fewer missed meal boluses per week in youth with type 1 diabetes using continuous subcutaneous insulin infusion (CSII) therapy. RESEARCH DESIGN AND METHODS:This was a randomized trial of 48 youth using CSII, who were ...

journal_title：Diabetes care

authors： Chase HP,Horner B,McFann K,Yetzer H,Gaston J,Banion C,Fiallo-Scharer R,Slover R,Klingensmith G

更新日期：2006-05-01 00:00:00

abstract：OBJECTIVE:To determine the proportion of adults with diabetes in the U.S. who have received diabetes patient education and to assess factors that determine whether patients receive this education. RESEARCH DESIGN AND METHODS:A questionnaire on diabetes was administered to a representative sample of 2,405 diabetic indi...

journal_title：Diabetes care

authors： Coonrod BA,Betschart J,Harris MI

更新日期：1994-08-01 00:00:00

abstract：OBJECTIVE:The intraoral tactile sensitivity (ITS) of diabetic and nondiabetic subjects was compared. The effects of age, ethnicity, sex, and intraoral site were considered. RESEARCH DESIGN AND METHODS:The sample comprised 589 participants of the Oral Health: San Antonio Longitudinal Study of Aging. A total of 107 subj...

journal_title：Diabetes care

authors： Shinkai RS,Hatch JP,Cornell JE,Yeh CK

更新日期：2004-04-01 00:00:00

abstract：OBJECTIVE:A 1-year randomized prospective study was conducted to investigate the efficacy of feedback from split-sample testing as part of a capillary blood glucose quality assurance program. RESEARCH DESIGN AND METHODS:A total of 124 nurses were randomized to either group A (quarterly comparisons with feedback) or gr...

journal_title：Diabetes care

authors： Jones HE,Cleave B,Zinman B,Szalai JP,Nichol HL,Hoffman BR

更新日期：1996-02-01 00:00:00

abstract：OBJECTIVE:To determine whether increasing doses (amounts) of beta-glucan present in an extruded breakfast cereal affect the glycemic and insulinemic responses in eight NIDDM subjects, compared with the same responses after a continental breakfast (bread, milk, cheese, ham). RESEARCH DESIGN AND METHODS:Breakfast cereal...

journal_title：Diabetes care

authors： Tappy L,Gügolz E,Würsch P

更新日期：1996-08-01 00:00:00

abstract：OBJECTIVE:This double-blind, placebo-controlled, randomized, multicenter, parallel-group study compared the efficacy, safety, and tolerability of Technosphere insulin with Technosphere powder as placebo in insulin-naive type 2 diabetic patients whose diabetes was suboptimally controlled with oral antidiabetic agents. ...

journal_title：Diabetes care

authors： Rosenstock J,Bergenstal R,Defronzo RA,Hirsch IB,Klonoff D,Boss AH,Kramer D,Petrucci R,Yu W,Levy B,0008 Study Group.

更新日期：2008-11-01 00:00:00

abstract：OBJECTIVE:Strict glycemic control in people with insulin-dependent diabetes mellitus (IDDM) reduces the risk of microvascular complications, but improvements in control are also associated with weight gain. Fears about the mortality risks of obesity may limit the acceptability of tight control. Therefore, we examined m...

journal_title：Diabetes care

authors： Chaturvedi N,Stevens LK,Fuller JH

更新日期：1995-06-01 00:00:00

abstract：OBJECTIVE:Glycemic control using inhaled, dry-powder insulin plus a single injection of long-acting insulin was compared with a conventional regimen in patients with type 2 diabetes, which was previously managed with at least two daily insulin injections. RESEARCH DESIGN AND METHODS:Patients were randomized to 6 month...

journal_title：Diabetes care

authors： Hollander PA,Blonde L,Rowe R,Mehta AE,Milburn JL,Hershon KS,Chiasson JL,Levin SR

更新日期：2004-10-01 00:00:00

abstract：OBJECTIVE:Defects in insulin secretion and insulin action are the major abnormalities in the development of type 2 diabetes. In middle-aged subjects, elevated plasma proinsulin has been found to predict type 2 diabetes. Therefore, our aim was to study the longitudinal relationships between baseline determinations of in...

journal_title：Diabetes care

authors： Zethelius B,Hales CN,Lithell HO,Berne C

更新日期：2004-06-01 00:00:00

abstract：OBJECTIVE:In diabetes, the persistence of hyperglycemia has been reported to cause increased production of oxygen free radicals through glucose autooxidation and nonenzymatic glycation. The aim of this study was to determine whether oxidative cellular damage occurs at the clinical onset of diabetes and in later stages ...

journal_title：Diabetes care

authors： Domínguez C,Ruiz E,Gussinye M,Carrascosa A

更新日期：1998-10-01 00:00:00

abstract：OBJECTIVE:Type 1 diabetes mellitus causes increased carotid intima-media thickness (IMT) in adults. We evaluated IMT in young subjects with type 1 diabetes. RESEARCH DESIGN AND METHODS:Participants with type 1 diabetes (N = 402) were matched to controls (N = 206) by age, sex, and race or ethnicity. Anthropometric and ...

journal_title：Diabetes care

authors： Urbina EM,Dabelea D,D'Agostino RB Jr,Shah AS,Dolan LM,Hamman RF,Daniels SR,Marcovina S,Wadwa RP

更新日期：2013-09-01 00:00:00

abstract：OBJECTIVE:To provide a description of the clinical characteristics that distinguish individuals who withhold insulin for weight control from those who do not. Some individuals with insulin-dependent diabetes mellitus (IDDM) control their weight by withholding insulin and purging excessive calories. This process places ...

journal_title：Diabetes care

authors： Biggs MM,Basco MR,Patterson G,Raskin P

更新日期：1994-10-01 00:00:00

abstract：OBJECTIVE:To assess the association of hypoglycemic treatment regimens with cardiovascular adverse events and mortality in a large population of type 2 diabetic patients at increased cardiovascular risk. RESEARCH DESIGN AND METHODS:This analysis included 8,192 overweight patients with type 2 diabetes from the Sibutram...

journal_title：Diabetes care

authors： Ghotbi AA,Køber L,Finer N,James WP,Sharma AM,Caterson I,Coutinho W,Van Gaal LF,Torp-Pedersen C,Andersson C

更新日期：2013-11-01 00:00:00

abstract：OBJECTIVE:To provide reliable data on the incidence of insulin-dependent diabetes mellitus (IDDM) in children (< 15 years of age) in Avellaneda, Argentina. RESEARCH DESIGN AND METHODS:A registry was established in Avellaneda, Argentina. The first registry was started in 1989, retrospective data collection was updated ...

journal_title：Diabetes care

authors： Sereday MS,Martí ML,Damiano MM,Moser ME

更新日期：1994-09-01 00:00:00

abstract：OBJECTIVE:To assess the prevalence of diabetes and prediabetes and the associated risk factors in two Asian Indian populations living in different environments. RESEARCH DESIGN AND METHODS:We performed cross-sectional analyses, using representative samples of 2,305 Asian Indians aged 40-84 years living in Chennai, Ind...

journal_title：Diabetes care

authors： Gujral UP,Narayan KM,Pradeepa RG,Deepa M,Ali MK,Anjana RM,Kandula NR,Mohan V,Kanaya AM

更新日期：2015-07-01 00:00:00

abstract：OBJECTIVE:To determine whether using the chronic care model (CCM) in an underserved community leads to improved clinical and behavioral outcomes for people with diabetes. RESEARCH DESIGN AND METHODS:This multilevel, cluster-design, randomized controlled trial examined the effectiveness of a CCM-based intervention in a...

journal_title：Diabetes care

authors： Piatt GA,Orchard TJ,Emerson S,Simmons D,Songer TJ,Brooks MM,Korytkowski M,Siminerio LM,Ahmad U,Zgibor JC

更新日期：2006-04-01 00:00:00

abstract：:One-third of men with obesity or type 2 diabetes have subnormal free testosterone concentrations. The lower free testosterone concentrations are observed in obese men at all ages, including adolescents at completion of puberty. The gonadotropin concentrations in these males are inappropriately normal; thus, these pati...

journal_title：Diabetes care

authors： Dhindsa S,Ghanim H,Batra M,Dandona P

更新日期：2018-07-01 00:00:00

abstract：OBJECTIVE:In adults with diabetes, in vivo platelet activation is a marker for atherosclerosis and cardiovascular disease (CVD). This pilot study investigated whether adolescents with diabetes had evidence of increased in vivo platelet activation. RESEARCH DESIGN AND METHODS:In vivo platelet activation was compared in...

journal_title：Diabetes care

authors： Israels SJ,McNicol A,Dean HJ,Cognasse F,Sellers EA

更新日期：2014-08-01 00:00:00

abstract：OBJECTIVE:Participants in ADVANCE were drawn from many countries. We examined whether the effects of intensive glycemic control on major outcomes in ADVANCE differ between participants from Asia, established market economies (EMEs), and eastern Europe. RESEARCH DESIGN AND METHODS:ADVANCE was a clinical trial of 11,140...

journal_title：Diabetes care

authors： Woodward M,Patel A,Zoungas S,Liu L,Pan C,Poulter N,Januszewicz A,Tandon N,Joshi P,Heller S,Neal B,Chalmers J

更新日期：2011-12-01 00:00:00

abstract：OBJECTIVE:To determine whether adolescents with type 1 diabetes have left ventricular functional changes at rest and during acute exercise and whether these changes are affected by metabolic control and diabetes duration. RESEARCH DESIGN AND METHODS:The study evaluated 53 adolescents with type 1 diabetes and 22 contro...

journal_title：Diabetes care

authors： Gusso S,Pinto TE,Baldi JC,Robinson E,Cutfield WS,Hofman PL

更新日期：2012-10-01 00:00:00

abstract：OBJECTIVE:To determine whether overweight Latino children with impaired fasting glucose (IFG) (> or = 100 mg/dl) have increased insulin resistance or decreased beta-cell function compared with those with normal fasting glucose (NFG). RESEARCH DESIGN AND METHODS:We studied 207 healthy overweight Latino children, aged 8...

journal_title：Diabetes care

authors： Weigensberg MJ,Ball GD,Shaibi GQ,Cruz ML,Goran MI

更新日期：2005-10-01 00:00:00

abstract：OBJECTIVE:This study investigated whether glucose readings from a sensor sampling in interstitial fluid differ substantially from blood glucose (BG) values measured at the same time. RESEARCH DESIGN AND METHODS:We have evaluated the relationship between BG and glucose extracted from interstitial fluid using the GlucoW...

journal_title：Diabetes care

authors： Kulcu E,Tamada JA,Reach G,Potts RO,Lesho MJ

更新日期：2003-08-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to study the association between a parental history of type 2 diabetes and the metabolic profile as well as the presence of the metabolic syndrome and diabetes complications in patients with type 1 diabetes. RESEARCH DESIGN AND METHODS:This was a cross-sectional study design in ...

journal_title：Diabetes care

authors： Thorn LM,Forsblom C,Wadén J,Söderlund J,Rosengård-Bärlund M,Saraheimo M,Heikkilä O,Hietala K,Pettersson-Fernholm K,Ilonen J,Groop PH,FinnDiane Study Group.

更新日期：2009-01-01 00:00:00

abstract：OBJECTIVE:To determine whether impairments in neurocognitive functioning are detectable at type 1 diabetes diagnosis and associated with subsequent glycemic control. RESEARCH DESIGN AND METHODS:Children/adolescents (N = 147) aged 5-18 years completed neuropsychological testing during their inpatient hospitalization fo...

journal_title：Diabetes care

authors： Schwartz DD,Axelrad ME,Anderson BJ

更新日期：2014-09-01 00:00:00

abstract：OBJECTIVE:Stress hyperglycemia increases the risk of mortality and poor outcomes in patients with acute myocardial infarction (AMI). We aimed to assess effects of intravenous nicorandil administered before reperfusion on AMI patients with stress hyperglycemia. RESEARCH DESIGN AND METHODS:This study consisted of 158 co...

journal_title：Diabetes care

authors： Ishii H,Ichimiya S,Kanashiro M,Amano T,Matsubara T,Murohara T

更新日期：2006-02-01 00:00:00

abstract：OBJECTIVE:Success after islet transplantation can be defined in terms of insulin independence, C-peptide secretion, or glycemic control. These measures are interdependent and all need to be considered in evaluating beta-cell function after islet transplantation. For the current study, a composite beta-score was develop...

journal_title：Diabetes care

authors： Ryan EA,Paty BW,Senior PA,Lakey JR,Bigam D,Shapiro AM

更新日期：2005-02-01 00:00:00

abstract：:Heart rate variability (HRV) during deep breathing was studied with a neonatal heart monitor in 143 control subjects and 218 patients with diabetes (102 with IDDM and 116 with NIDDM). In the control group HRV decreased after age 20 by 4-5 beats per decade (from 29.7 +/- 5.8 beats at age 20-29 to 11.8 +/- 5.4 beats at ...

journal_title：Diabetes care

authors： Masaoka S,Lev-Ran A,Hill LR,Vakil G,Hon EH

更新日期：1985-01-01 00:00:00

abstract：OBJECTIVE:There is considerable interest in identifying biomarkers that predict high risk for the development of macrovascular complications in patients with diabetes. Therefore, the longitudinal association between subclinical atherosclerosis as measured by internal carotid artery intima-media thickness (IMT) and acut...

journal_title：Diabetes care

authors： Hunt KJ,Baker NL,Cleary PA,Klein R,Virella G,Lopes-Virella MF,DCCT\/EDIC Group of Investigators.

更新日期：2015-07-01 00:00:00

abstract：OBJECTIVE:Gestational diabetes mellitus (GDM) may cause obesity in the offspring. The objective was to assess the effect of treatment for mild GDM on the BMI of 4- to 5-year-old children. RESEARCH DESIGN AND METHODS:Participants were 199 mothers who participated in a randomized controlled trial of the treatment of mil...

journal_title：Diabetes care

authors： Gillman MW,Oakey H,Baghurst PA,Volkmer RE,Robinson JS,Crowther CA

更新日期：2010-05-01 00:00:00

abstract：OBJECTIVE:Gestational diabetes mellitus has been associated with offspring cardiac congenital malformations, ventricular hypertrophy, and diastolic dysfunction in large observational cohort studies and experimental animal models. We assessed the associations of maternal random glucose concentrations across the full ran...

journal_title：Diabetes care

authors： Wahab RJ,Jaddoe VWV,Roest AAW,Toemen L,Gaillard R

更新日期：2020-09-01 00:00:00