当前位置： SCI文献检索 > EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE期刊下所有文献 > Symptom changes in five dimensions of the Positive and Negative Syndrome Scale in refractory psychosis.

Symptom changes in five dimensions of the Positive and Negative Syndrome Scale in refractory psychosis.

Abstract：

:Refractory psychosis units currently have little information regarding which symptoms profiles should be expected to respond to treatment. In the current study, we provide this information using structural equation modeling of Positive and Negative Syndrome Scale (PANSS) ratings at admission and discharge on a sample of 610 patients admitted to a treatment refractory psychosis program at a Canadian tertiary care unit between 1990 and 2011. The hypothesized five-dimensional structure of the PANSS fit the data well at both admission and discharge, and the latent variable scores are reported as a function of symptom dimension and diagnostic category. The results suggest that, overall, positive symptoms (POS) responded to treatment better than all other symptoms dimensions, but for the schizoaffective and bipolar groups, greater response on POS was observed relative to the schizophrenia and major depression groups. The major depression group showed the most improvement on negative symptoms and emotional distress, and the bipolar group showed the most improvement on disorganization. Schizophrenia was distinct from schizoaffective disorder in showing reduced treatment response on all symptom dimensions. These results can assist refractory psychosis units by providing information on how PANSS symptom dimensions respond to treatment and how this depends on diagnostic category.

journal_name

Eur Arch Psychiatry Clin Neurosci

journal_title

European archives of psychiatry and clinical neuroscience

authors

Woodward TS,Jung K,Smith GN,Hwang H,Barr AM,Procyshyn RM,Flynn SW,van der Gaag M,Honer WG

doi

10.1007/s00406-013-0460-x

subject

Has Abstract

pub_date

2014-12-01 00:00:00

pages

673-82

issue

8

eissn

0940-1334

issn

1433-8491

journal_volume

264

pub_type

杂志文章

相关文献

EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE文献大全
  • Cerebral connectivity and psychotic personality traits. A diffusion tensor imaging study.

    abstract：:This study aims to investigate the relationship between regional connectivity in the brain white matter and the presence of psychotic personality traits, in healthy subjects with psychotic traits. Thirteen healthy controls were administered the MMPI-2, to assess psychotic traits and, according to MMPI results, a dicho...

    journal_title：European archives of psychiatry and clinical neuroscience

    pub_type： 杂志文章

    doi：10.1007/s00406-007-0796-1

    authors： Volpe U,Federspiel A,Mucci A,Dierks T,Frank A,Wahlund LO,Galderisi S,Maj M

    更新日期：2008-08-01 00:00:00

  • The concept of major depression. I. Descriptive comparison of six competing operational definitions including ICD-10 and DSM-III-R.

    abstract：:All operationalized diagnostic systems contain a diagnostic category, which corresponds to the concept of major depression. Yet, these corresponding definitions are not identical. Up to now, no comprehensive comparisons of the competing diagnoses have been published. We will therefore present a series of studies, desc...

    journal_title：European archives of psychiatry and clinical neuroscience

    pub_type： 杂志文章,评审

    doi：10.1007/BF02189537

    authors： Philipp M,Maier W,Delmo CD

    更新日期：1991-01-01 00:00:00

  • Rates and predictors of relapse in first-episode non-affective psychosis: a 3-year longitudinal study in a specialized intervention program (PAFIP).

    abstract：:Relapses may represent a critical hazard in schizophrenia spectrum disorders as they are associated with an increased risk of a clinical and functional deterioration. Preventing relapse after recovering from a first psychotic episode has become a major challenge due to its critical impact on lifelong functionality. Th...

    journal_title：European archives of psychiatry and clinical neuroscience

    pub_type： 杂志文章

    doi：10.1007/s00406-016-0740-3

    authors： Pelayo-Terán JM,Gajardo Galán VG,de la Ortiz-García de la Foz V,Martínez-García O,Tabarés-Seisdedos R,Crespo-Facorro B,Ayesa-Arriola R

    更新日期：2017-06-01 00:00:00

  • Prevention of rehospitalization in schizophrenia: results of an integrated care project in Germany.

    abstract：:The goal of this study was to prevent rehospitalizations and thus to optimize satisfaction with treatment and quality of life in patients suffering by schizophrenia or schizoaffective disorder. A complex intervention with improved cooperation between in- and outpatient services was applied to 46 "high utilizing" patie...

    journal_title：European archives of psychiatry and clinical neuroscience

    pub_type： 临床试验,杂志文章

    doi：10.1007/s00406-009-0056-7

    authors： Schmidt-Kraepelin C,Janssen B,Gaebel W

    更新日期：2009-11-01 00:00:00

  • Pituitary volumes in relatives of bipolar patients: high-risk study.

    abstract：BACKGROUND:Increased, decreased, as well as unchanged pituitary volumes have been reported in bipolar disorders (BD). It is unclear, whether abnormal pituitary volumes increase vulnerability for BD (primary vulnerability marker), or are secondary to burden of illness. To address this question, we performed the first hi...

    journal_title：European archives of psychiatry and clinical neuroscience

    pub_type： 杂志文章

    doi：10.1007/s00406-008-0804-0

    authors： Hajek T,Gunde E,Bernier D,Slaney C,Propper L,Macqueen G,Duffy A,Alda M

    更新日期：2008-09-01 00:00:00

  • Genetic risks of schizophrenia identified in a matched case-control study.

    abstract：:It has been suggested that dopaminergic neurotransmission plays important roles for the psychotic symptoms and probably etiology of schizophrenia. In our recent preliminary study, we demonstrated that the specific allele combinations of dopamine-related functional single nucleotide polymorphisms (SNPs), rs10770141, rs...

    journal_title：European archives of psychiatry and clinical neuroscience

    pub_type： 杂志文章

    doi：10.1007/s00406-020-01158-3

    authors： Oishi K,Niitsu T,Kanahara N,Sato Y,Iwayama Y,Toyota T,Hashimoto T,Sasaki T,Takase M,Shiina A,Yoshikawa T,Iyo M

    更新日期：2020-07-04 00:00:00

  • Obsessional personality features in employed Japanese adults with a lifetime history of depression: assessment by the Munich Personality Test (MPT).

    abstract：BACKGROUND:Although a number of studies have reported on the association between obsessional personality features as measured by the Munich Personality Test (MPT) "Rigidity" scale and depression, there has been no examination of these relationships in a non-clinical sample. METHODS:The dimensional scores on the MPT we...

    journal_title：European archives of psychiatry and clinical neuroscience

    pub_type： 杂志文章

    doi：10.1007/s004060170043

    authors： Sakado K,Sakado M,Seki T,Kuwabara H,Kojima M,Sato T,Someya T

    更新日期：2001-06-01 00:00:00

  • Clinical diagnosis of muscle cramp and muscular cramp syndromes.

    abstract：:The diagnosis of muscle cramp is based on clinical features. Algorithms are presented for the diagnosis of muscle cramp and cramp syndromes. ...

    journal_title：European archives of psychiatry and clinical neuroscience

    pub_type： 杂志文章,评审

    doi：10.1007/BF02191149

    authors： Jansen PH,Joosten EM,Vingerhoets HM

    更新日期：1991-01-01 00:00:00

  • Father-infant interaction patterns as precursors of children's later externalizing behavior problems: a longitudinal study over 11 years.

    abstract：AIM:This study examined the extent to which fathers' and infants' interaction behavior were related to children's externalizing behavior problems at age 8 and 11 years. METHODS:In a prospective longitudinal study of children at risk for later psychopathology, 72 fathers and their 3-month-old children were videotaped a...

    journal_title：European archives of psychiatry and clinical neuroscience

    pub_type： 杂志文章

    doi：10.1007/s00406-006-0642-x

    authors： Trautmann-Villalba P,Gschwendt M,Schmidt MH,Laucht M

    更新日期：2006-09-01 00:00:00

  • Psychiatric comorbidity and functional impairment in a clinically referred sample of adults with attention-deficit/hyperactivity disorder (ADHD).

    abstract：OBJECTIVE:This exploratory study aims to compare lifetime psychiatric axis-I-comorbidity and psychosocial functioning in a clinically referred sample of adult patients with attention-deficit/hyperactivity disorder (ADHD) with a population-based healthy control group and to examine whether patients with ADHD and lifetim...

    journal_title：European archives of psychiatry and clinical neuroscience

    pub_type： 杂志文章

    doi：10.1007/s00406-007-0712-8

    authors： Sobanski E,Brüggemann D,Alm B,Kern S,Deschner M,Schubert T,Philipsen A,Rietschel M

    更新日期：2007-10-01 00:00:00

  • The role of expectancies and emotional load in false auditory perceptions among patients with schizophrenia spectrum disorders.

    abstract：:Cognitive models suggest that top-down and emotional processes increase false perceptions in schizophrenia spectrum disorders (SSD). However, little is still known about the interaction of these processes in false auditory perceptions. The present study aimed at investigating the specific as well as joint impacts of e...

    journal_title：European archives of psychiatry and clinical neuroscience

    pub_type： 杂志文章

    doi：10.1007/s00406-019-01065-2

    authors： Gawęda Ł,Moritz S

    更新日期：2019-09-06 00:00:00

  • Substance P-like immunoreactivity and somatostatin-like immunoreactivity in the ventricular fluid of patients with chronic pain syndromes.

    abstract：:Substance P-like and somatostatin-like immunoreactivities (SPLI and SLI) were determined in ventricular fluid of patients with chronic pain syndromes and in a comparison group with multiple sclerosis, essential tremor, epilepsy and postanoxic myoclonus. Concentrations of SPLI and SLI were non-significantly decreased b...

    journal_title：European archives of psychiatry and clinical neuroscience

    pub_type： 杂志文章

    doi：10.1007/BF02191152

    authors： Jost S,Reuner C,Geiger J,Mohadjer M,Milios E,Cramer H

    更新日期：1991-01-01 00:00:00

  • Reliability of neural food cue-reactivity in participants with obesity undergoing bariatric surgery: a 26-week longitudinal fMRI study.

    abstract：:Obesity is highly prevalent worldwide and results in a high disease burden. The efforts to monitor and predict treatment outcome in participants with obesity using functional magnetic resonance imaging (fMRI) depends on the reliability of the investigated task-fMRI brain activation. To date, no study has investigated ...

    journal_title：European archives of psychiatry and clinical neuroscience

    pub_type： 杂志文章

    doi：10.1007/s00406-020-01218-8

    authors： Bach P,Grosshans M,Koopmann A,Kienle P,Vassilev G,Otto M,Bumb JM,Kiefer F

    更新日期：2020-12-17 00:00:00

  • Altered intrinsic organisation of brain networks implicated in attentional processes in adult attention-deficit/hyperactivity disorder: a resting-state study of attention, default mode and salience network connectivity.

    abstract：:Deficits in task-related attentional engagement in attention-deficit/hyperactivity disorder (ADHD) have been hypothesised to be due to altered interrelationships between attention, default mode and salience networks. We examined the intrinsic connectivity during rest within and between these networks. Six-minute resti...

    journal_title：European archives of psychiatry and clinical neuroscience

    pub_type： 杂志文章

    doi：10.1007/s00406-015-0630-0

    authors： Sidlauskaite J,Sonuga-Barke E,Roeyers H,Wiersema JR

    更新日期：2016-06-01 00:00:00

  • Cannabis use in pregnancy and early life and its consequences: animal models.

    abstract：:Cannabinoid receptors and their endogenous ligands have been detected from the earliest stages of embryonic development. The endocannabinoid system appears to play essential roles in these early stages for neuronal development and cell survival, although its detailed involvement in fundamental developmental processes ...

    journal_title：European archives of psychiatry and clinical neuroscience

    pub_type： 杂志文章,评审

    doi：10.1007/s00406-009-0026-0

    authors： Schneider M

    更新日期：2009-10-01 00:00:00

  • Meta-analyses: a method to maximise the evidence from clinical studies?

    abstract：:Evidence-based medicine (EBM) is becoming the guiding principle for clinical treatment decisions. But evidence remains a loosely defined term. Multiple criteria for evidence criteria have been proposed. Most influential evidence criteria give priority to meta-analyses because they promise an objective procedure to com...

    journal_title：European archives of psychiatry and clinical neuroscience

    pub_type： 杂志文章

    doi：10.1007/s00406-009-0068-3

    authors： Maier W,Möller HJ

    更新日期：2010-02-01 00:00:00

  • Early-onset Alzheimer's disease due to mutations of the presenilin-1 gene on chromosome 14: a 7-year follow-up of a patient with a mutation at codon 139.

    abstract：:Mutations in the presenilin-1 gene (PS-1 gene) on chromosome 14 have recently been identified as a cause of familial early-onset Alzheimer's disease (EOAD). To our knowledge, only two German EOAD patients with mutations in the PS-1 gene have been identified thus far. Herein we report the case of a German EOAD patient ...

    journal_title：European archives of psychiatry and clinical neuroscience

    pub_type： 杂志文章

    doi：10.1007/s004060050028

    authors： Hüll M,Fiebich BL,Dykierek P,Schmidtke K,Nitzsche E,Orszagh M,Deuschl G,Moser E,Schumacher M,Lücking C,Berger M,Bauer J

    更新日期：1998-01-01 00:00:00

  • Thalamocortical connectivity during resting state in schizophrenia.

    abstract：:Schizophrenia has been linked to disturbed connectivity between large-scale brain networks. Altered thalamocortical connectivity might be a major mechanism mediating regionally distributed dysfunction, yet it is only incompletely understood. We analysed functional magnetic resonance imaging data obtained during restin...

    journal_title：European archives of psychiatry and clinical neuroscience

    pub_type： 杂志文章

    doi：10.1007/s00406-013-0417-0

    authors： Klingner CM,Langbein K,Dietzek M,Smesny S,Witte OW,Sauer H,Nenadic I

    更新日期：2014-03-01 00:00:00

  • Lifetime cannabis use and cognition in patients with schizophrenia spectrum disorders and their unaffected siblings.

    abstract：:The relationship between cannabis and cognitive performance is controversial. While both acute administration and long-term cannabis use impair cognitive performance in healthy subjects, several studies have shown improved cognitive outcomes in patients with schizophrenia spectrum disorders who use cannabis. The aim o...

    journal_title：European archives of psychiatry and clinical neuroscience

    pub_type： 杂志文章

    doi：10.1007/s00406-013-0404-5

    authors： Sánchez-Torres AM,Basterra V,Rosa A,Fañanás L,Zarzuela A,Ibáñez B,Peralta V,Cuesta MJ

    更新日期：2013-12-01 00:00:00

  • Optimized voxel brain morphometry: association between brain volumes and the response to atypical antipsychotics.

    abstract：:To date, few studies have addressed the relationship between brain structure alterations and responses to atypical antipsychotics in schizophrenia. To this end, in this study, magnetic resonance imaging (MRI) and voxel-based morphometry (VBM) were used to assess the relationship between the brain volumes of gray (GM) ...

    journal_title：European archives of psychiatry and clinical neuroscience

    pub_type： 杂志文章

    doi：10.1007/s00406-010-0182-2

    authors： Molina V,Martín C,Ballesteros A,de Herrera AG,Hernández-Tamames JA

    更新日期：2011-09-01 00:00:00

  • Risperidone and haloperidol promote survival of stem cells in the rat hippocampus.

    abstract：:Altered neuroplasticity contributes to the pathophysiology of schizophrenia. However, the idea that antipsychotics may act, at least in part, by normalizing neurogenesis has not been consistently supported. Our study seeks to determine whether hippocampal cell proliferation is altered in adult rats pretreated with ket...

    journal_title：European archives of psychiatry and clinical neuroscience

    pub_type： 杂志文章

    doi：10.1007/s00406-009-0033-1

    authors： Keilhoff G,Grecksch G,Bernstein HG,Roskoden T,Becker A

    更新日期：2010-03-01 00:00:00

  • EPA guidance on mental health and economic crises in Europe.

    abstract：:This European Psychiatric Association (EPA) guidance paper is a result of the Working Group on Mental Health Consequences of Economic Crises of the EPA Council of National Psychiatric Associations. Its purpose is to identify the impact on mental health in Europe of the economic downturn and the measures that may be ta...

    journal_title：European archives of psychiatry and clinical neuroscience

    pub_type： 杂志文章,评审

    doi：10.1007/s00406-016-0681-x

    authors： Martin-Carrasco M,Evans-Lacko S,Dom G,Christodoulou NG,Samochowiec J,González-Fraile E,Bienkowski P,Gómez-Beneyto M,Dos Santos MJ,Wasserman D

    更新日期：2016-03-01 00:00:00

  • Diagnosis and six-month stability of negative symptoms in psychotic disorders.

    abstract：:Negative symptoms were examined in 150 primarily first-admission patients diagnosed with schizophrenia, schizoaffective disorder, psychotic depression, psychotic bipolar disorder, and 'other' psychoses. The analysis focused on patients who were rated on the Scale for the Assessment of Negative Symptoms (SANS) within 4...

    journal_title：European archives of psychiatry and clinical neuroscience

    pub_type： 临床试验,杂志文章

    doi：10.1007/BF02274895

    authors： Fennig S,Bromet EJ,Galambos N,Putnam K

    更新日期：1996-01-01 00:00:00

  • Homeless people at disadvantage in mental health services.

    abstract：OBJECTIVE:The aims of this study are threefold: to depict characteristics of homeless at discharge from a psychiatric hospital; to describe the utilisation of inpatient care and treatment measures during hospitalisation; and to analyse to what extent psychiatric disorders and clinical variables contribute to the risk f...

    journal_title：European archives of psychiatry and clinical neuroscience

    pub_type： 杂志文章

    doi：10.1007/s00406-005-0616-4

    authors： Lauber C,Lay B,Rössler W

    更新日期：2006-04-01 00:00:00

  • Classical conditioning in borderline personality disorder: an fMRI study.

    abstract：:Previous research suggests disturbed emotional learning and memory in borderline personality disorder (BPD). Studies investigating the neural correlates of aversive differential delay conditioning in BPD are currently lacking. We aimed to investigate acquisition, within-session extinction, between-session extinction r...

    journal_title：European archives of psychiatry and clinical neuroscience

    pub_type： 杂志文章

    doi：10.1007/s00406-015-0593-1

    authors： Krause-Utz A,Keibel-Mauchnik J,Ebner-Priemer U,Bohus M,Schmahl C

    更新日期：2016-06-01 00:00:00

  • Remitted schizophrenia-spectrum patients with spared working memory show information processing abnormalities.

    abstract：:Working memory and information processing abnormalities are often reported in schizophrenia. The aim of this study was to examine visual backward masking (BM) functions in remitted schizophrenia-spectrum patients with spared working memory functions. Seventy-two patients with DSM-IV schizophrenia-spectrum disorders we...

    journal_title：European archives of psychiatry and clinical neuroscience

    pub_type： 杂志文章

    doi：10.1007/s004060170054

    authors： Kéri S,Szendi I,Kelemen O,Benedek G,Janka Z

    更新日期：2001-01-01 00:00:00

  • Characterization of spontaneous Parkinsonism in drug-naive patients with nonaffective psychotic disorders.

    abstract：:Spontaneous Parkinsonism (SP) in schizophrenia-related disorders is poorly characterized. The objective of this study was to examine the concordance and clinical validity of alternative definitions of SP in patients with nonaffective psychotic disorders. Two-hundred drug-naive patients with nonaffective psychotic diso...

    journal_title：European archives of psychiatry and clinical neuroscience

    pub_type： 杂志文章

    doi：10.1007/s00406-011-0219-1

    authors： Peralta V,Basterra V,Campos MS,de Jalón EG,Moreno-Izco L,Cuesta MJ

    更新日期：2012-03-01 00:00:00

  • The neural correlates of ego-disturbances (passivity phenomena) and formal thought disorder in schizophrenia.

    abstract：:Ego-disturbances (passivity phenomena) and formal thought disorder are two hallmark symptoms of schizophrenia. Formal thought disorder has been highlighted already very early by Eugen Bleuler in his concept of basic symptoms (Grundsymptome). In contrast ego-disturbances (Ich-Störungen) or passivity phenomena have been...

    journal_title：European archives of psychiatry and clinical neuroscience

    pub_type： 杂志文章,评审

    doi：10.1007/s00406-008-5017-z

    authors： Leube D,Whitney C,Kircher T

    更新日期：2008-11-01 00:00:00

  • Dopamine D1 receptor number--a sensitive PET marker for early brain degeneration in Huntington's disease.

    abstract：:D1-dopamine receptor binding in the brain was determined by positron emission tomography (PET) in five patients with Huntington's disease, in one asymptomatic gene carrier and in five control subjects. [11C] SCH 23390 was used as the radioligand. Brain morphology was recorded by MRI. The patients who all had a mild to...

    journal_title：European archives of psychiatry and clinical neuroscience

    pub_type： 杂志文章

    doi：10.1007/BF02191583

    authors： Sedvall G,Karlsson P,Lundin A,Anvret M,Suhara T,Halldin C,Farde L

    更新日期：1994-01-01 00:00:00

  • Episodic course in obsessive-compulsive disorder.

    abstract：:The course of obsessive-compulsive disorder (OCD) is variable, ranging from episodic to chronic. We hypothesised that the former course is more likely to be related to bipolar mood disorders. With the use of a specially constructed OCD questionnaire, we studied 135 patients fulfilling DSM-III-R criteria for OCD with a...

    journal_title：European archives of psychiatry and clinical neuroscience

    pub_type： 杂志文章

    doi：10.1007/s004060050044

    authors： Perugi G,Akiskal HS,Gemignani A,Pfanner C,Presta S,Milanfranchi A,Lensi P,Ravagli S,Maremmani I,Cassano GB

    更新日期：1998-01-01 00:00:00