Episodic course in obsessive-compulsive disorder.

abstract：:The ability of humans to predict and explain other people's behaviour by attributing independent mental states such as desires and beliefs to them, is considered to be due to our ability to construct a "Theory of Mind". Recently, several neuroimaging studies have implicated the medial frontal lobes as playing a critic...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Mazza M,Costagliola C,Di Michele V,Magliani V,Pollice R,Ricci A,Di Giovanbattista E,Roncone R,Casacchia M,Galzio RJ

更新日期：2007-02-01 00:00:00

abstract：:Evidence-based medicine (EBM) is becoming the guiding principle for clinical treatment decisions. But evidence remains a loosely defined term. Multiple criteria for evidence criteria have been proposed. Most influential evidence criteria give priority to meta-analyses because they promise an objective procedure to com...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Maier W,Möller HJ

更新日期：2010-02-01 00:00:00

abstract：:Smooth-pursuit eye-tracking performance was examined in 100 schizophrenic patients and various control groups under both attention-enhancing and attention-distracting conditions. The level of attentional demand was varied by introducing a secondary reaction time task that directed attention either toward or away from ...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Schlenker R,Cohen R,Berg P,Hubman W,Mohr F,Watzl H,Werther P

更新日期：1994-01-01 00:00:00

abstract：OBJECTIVE:The goal of this study was to identify adverse effects of the atypical neuroleptic clozapine on liver function and lipid metabolism. METHODS:Data which included serum levels of clozapine and its hepatic metabolite N-desmethyl clozapine were collected from medical records of patients treated with clozapine an...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Wiltfang J,Schenk-Daprá B,Stiens G,Bleich S,Bandelow B,Müller P,Niedmann PD,Armstrong VW,Rüther E

更新日期：2001-12-01 00:00:00

abstract：:During a course of electroconvulsive therapy (ECT), the level of currency necessary to induce an epileptic seizure in a patient may either remain relatively stable or-more often-may require repeated upward adjustment over time due to a constantly increasing seizure threshold. We aimed to determine whether a common pol...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Stephani C,Shoukier M,Ahmed R,Wolff-Menzler C

更新日期：2017-12-01 00:00:00

abstract：:Suicide is a tremendous threat to global public health, and a large number of people who committed suicide suffered the pain of mental diseases, especially major depressive disorder (MDD). Previous study showed that ketamine could reduce suicidal ideation (SI), potentially by improving the impaired working memory (WM)...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Chen X,Wang M,Hu Y,Zhan Y,Zhou Y,Zheng W,Liu W,Wang C,Zhong X,Li H,Lan X,Ning Y,Zhang B

更新日期：2021-01-01 00:00:00

abstract：:The hippocampus seems to be affected in MDD, and brain-derived neurotrophic factor (BDNF) has positive effects on neurogenesis within the hippocampus. Although there are inconsistencies among study results, a smaller hippocampal volume in depressed patients is thought to be related to the pathophysiology of the diseas...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Eker C,Kitis O,Taneli F,Eker OD,Ozan E,Yucel K,Coburn K,Gonul AS

更新日期：2010-10-01 00:00:00

abstract：:This paper reports on psychiatric case identification by the application of the Structured Clinical Interview for DSM-III-R (SCID) in a sample of 198 Greek migrants repatriated from western europe in a northwestern province of Greece. The current (1 month) prevalence of psychiatric morbidity, based on the total number...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Bilanakis N,Madianos MG,Liakos A

更新日期：1995-01-01 00:00:00

abstract：:Alzheimer's disease (AD) is characterized neuropathologically by the presence of amyloid plaques, neuritic plaques, and neurofibrillary tangles (NFTs). These lesions occur not only in demented individuals with AD but also in non-demented persons. In non-demented individuals, amyloid and neuritic plaques are usually ac...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Thal DR,von Arnim C,Griffin WS,Yamaguchi H,Mrak RE,Attems J,Upadhaya AR

更新日期：2013-11-01 00:00:00

abstract：:Scientific progress fostered in DSM and ICD over the past quarter of century has significantly increased awareness of the limitation of categorical definitions of mental illness. Disorders highly merge into another with no natural boundary in between. The addition of continuous, "dimensional" measures into the various...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Okasha A

更新日期：2009-11-01 00:00:00

abstract：:Visually scored and power spectral analyses (PSA) of polysomnography (PSG) recordings reveal abnormalities in alcohol dependence (AD) and major depressive disorder (MDD), including deficiencies in slow wave activity (SWA) during non-rapid eye movement (NREM) sleep. SWA parameters reflect the integrity of the homeostat...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Brower KJ,Hoffmann R,Conroy DA,Arnedt JT,Armitage R

更新日期：2011-12-01 00:00:00

abstract：:Impaired perceptual inference has been suggested to be at the core of positive symptoms in schizophrenia. Apparent motion (AM) is a visual illusion in which perceptual inference gives rise to the experience of a single object moving back and forth when two spatially separated objects are flashed in alternation. Here, ...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Sanders LL,de Millas W,Heinz A,Kathmann N,Sterzer P

更新日期：2013-04-01 00:00:00

abstract：:The purpose of this study was to investigate the relationship between specific symptom severity and D2/3 receptor availability in extrastriatal regions in outpatients with schizophrenia to shed light on the role of extrastriatal dopaminergic neurotransmission in the pathophysiology of symptoms of schizophrenia. Sixtee...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Joo YH,Kim JH,Son YD,Kim HK,Shin YJ,Lee SY,Kim JH

更新日期：2018-09-01 00:00:00

abstract：:Previous research suggests disturbed emotional learning and memory in borderline personality disorder (BPD). Studies investigating the neural correlates of aversive differential delay conditioning in BPD are currently lacking. We aimed to investigate acquisition, within-session extinction, between-session extinction r...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Krause-Utz A,Keibel-Mauchnik J,Ebner-Priemer U,Bohus M,Schmahl C

更新日期：2016-06-01 00:00:00

abstract：:Astrocytes are the most numerous cell type within the central nervous system. Early during development they act as guiding structures for migratory neurons; later they are not only the main source for nutrients and growth factors in the brain, but they are also communication partners of neighboring neurons. For this p...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Kirchhoff F,Dringen R,Giaume C

更新日期：2001-08-01 00:00:00

abstract：:The relationship between lateral ventricular size or its asymmetry and age at the onset of schizophrenia was investigated in 20 schizophrenic patients diagnosed according to DSM-III-R criteria. The ventricle-brain ratio (VBR) was determined using three transaxial slices of magnetic resonance image (MRI) and asymmetry ...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Aso M,Kurachi M,Suzuki M,Yuasa S,Matsui M,Saitoh O

更新日期：1995-01-01 00:00:00

abstract：:Germany turned towards community-based mental health care in the mid seventies, during a general climate of social and political reform. The continuing deinstitutionalisation process and the implementation of community mental health services was considerably affected by the reunification of East and West Germany in 19...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Salize HJ,Rössler W,Becker T

更新日期：2007-03-01 00:00:00

abstract：:Relapses may represent a critical hazard in schizophrenia spectrum disorders as they are associated with an increased risk of a clinical and functional deterioration. Preventing relapse after recovering from a first psychotic episode has become a major challenge due to its critical impact on lifelong functionality. Th...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Pelayo-Terán JM,Gajardo Galán VG,de la Ortiz-García de la Foz V,Martínez-García O,Tabarés-Seisdedos R,Crespo-Facorro B,Ayesa-Arriola R

更新日期：2017-06-01 00:00:00

abstract：:This 4-6-year prospective follow-up study compared reactive depressives with (n = 48) and without suicide attempts before index admission (n = 24). Both groups showed a favourable course and outcome concerning psychiatric diagnoses (DSM-III), psychopathology, social integration, and social functioning as well as displ...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Bronisch T,Hecht H

更新日期：1992-01-01 00:00:00

abstract：:Despite the lack of clinical data about the role of the endocannabinoid system (ECS) in affective disorders, preclinical work suggests that the ECS is relevant in both with regard to the etiology of depression as well as the mediation of antidepressant effects. We measured the intraindividual levels of the endocannabi...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Kranaster L,Hoyer C,Aksay SS,Bumb JM,Leweke FM,Janke C,Thiel M,Lutz B,Bindila L,Sartorius A

更新日期：2017-12-01 00:00:00

abstract：:Obsessive-compulsive symptoms (OCS) in patients with schizophrenia are a common co-occurring condition, often associated with additional impairments. A subgroup of these patients develops OCS during treatment with second-generation antipsychotics (SGAs), most importantly clozapine and olanzapine. So far, little is kno...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Mier D,Schirmbeck F,Stoessel G,Esslinger C,Rausch F,Englisch S,Eisenacher S,de Haan L,Meyer-Lindenberg A,Kirsch P,Zink M

更新日期：2019-12-01 00:00:00

abstract：:In a retrospective matched-pairs study the efficacy of azathioprine treatment was compared with no treatment over a period of at least 10 years. Of 277 patients with clinically definite multiple sclerosis seen during the years 1973 and 1974, 42 pairs were selected by similarity in disability score, sex, age and diseas...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Kappos L,Heun R,Mertens HG

更新日期：1990-01-01 00:00:00

abstract：:Deficits in task-related attentional engagement in attention-deficit/hyperactivity disorder (ADHD) have been hypothesised to be due to altered interrelationships between attention, default mode and salience networks. We examined the intrinsic connectivity during rest within and between these networks. Six-minute resti...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Sidlauskaite J,Sonuga-Barke E,Roeyers H,Wiersema JR

更新日期：2016-06-01 00:00:00

abstract：:Despite clues indicating high Bullying at the Work Place (BWP) rates in French hospitals, there has been no quantitative study so far. To determine the prevalence of repeated BWP in a national sample of French young physicians; its risk factors, and the mental health consequences of BWP. The study is a cross-sectional...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Messiaen M,Duba A,Boulangeat C,Boucekine M,Bourbon A,Viprey M,Auquier P,Lançon C,Boyer L,Fond G

更新日期：2020-05-27 00:00:00

abstract：:The impact of obsessive-compulsive symptoms on functioning in schizophrenia is still debated. This study investigated the relationship between OC symptoms and functioning along a severity gradient of obsessive-compulsive dimension. Sixty patients affected by schizophrenia completed the SCID-IV, the Positive and Negati...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Tonna M,Ottoni R,Paglia F,Ossola P,De Panfilis C,Marchesi C

更新日期：2016-02-01 00:00:00

abstract：:This report presents the rationale and design of a multi-center clinical trial that examines the efficacy and safety of antipsychotic combination treatment in acutely ill schizophrenia patients compared to antipsychotic monotherapy. Antipsychotic combination treatment is common in clinical practice worldwide, despite ...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Schmidt-Kraepelin C,Feyerabend S,Engelke C,Riesbeck M,Meisenzahl-Lechner E,Gaebel W,Verde PE,Kolbe H,Correll CU,Leucht S,Heres S,Kluge M,Makiol C,Neff A,Lange C,Englisch S,Zink M,Langguth B,Poeppl T,Reske D,Gouzou

更新日期：2020-02-01 00:00:00

abstract：:Besides the ventral tegmental area and the nucleus accumbens as the most investigated brain reward structures, several reports about the relation between volume and activity of the amygdala and drug-seeking behavior have emphasized the central role of the amygdala in the etiology of addiction. Considering its proposed...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Zill P,Vielsmeier V,Büttner A,Eisenmenger W,Siedler F,Scheffer B,Möller HJ,Bondy B

更新日期：2011-03-01 00:00:00

abstract：:Mutations in the presenilin-1 gene (PS-1 gene) on chromosome 14 have recently been identified as a cause of familial early-onset Alzheimer's disease (EOAD). To our knowledge, only two German EOAD patients with mutations in the PS-1 gene have been identified thus far. Herein we report the case of a German EOAD patient ...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Hüll M,Fiebich BL,Dykierek P,Schmidtke K,Nitzsche E,Orszagh M,Deuschl G,Moser E,Schumacher M,Lücking C,Berger M,Bauer J

更新日期：1998-01-01 00:00:00

abstract：:As a result of the multifactorial etiopathology of schizophrenia, a treatment strategy combining drug therapy with psychosocial measures is indicated. Depending on the stage of the disease and on the individual condition of the patient, the accent is set alternatively more on one approach or on the other. However, und...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Möller HJ

更新日期：1996-01-01 00:00:00

abstract：:Early life maltreatment (ELM) has long-lasting effects on social interaction. When interacting with their own child, women with ELM often report difficulties in parenting and show reduced maternal sensitivity. Sensitive maternal behavior requires the recognition of the child's emotional state depicted in its facial em...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Neukel C,Herpertz SC,Hinid-Attar C,Zietlow AL,Fuchs A,Moehler E,Bermpohl F,Bertsch K

更新日期：2019-03-01 00:00:00