Polymorphism of the brain-derived neurotrophic factor and dynamics of the seizure threshold of electroconvulsive therapy.

abstract：:Cannabinoid 1 receptor and glutamatergic dysfunction have both been implicated in the pathophysiology of schizophrenia. However, it remains unclear if cannabinoid 1 receptor alterations shown in drug-naïve/free patients with first episode psychosis may be linked to glutamatergic alterations in the illness. We aimed to...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Borgan F,Veronese M,Reis Marques T,Lythgoe DJ,Howes O

更新日期：2020-09-28 00:00:00

abstract：:Gamma oscillations are key in coordinating brain activity and seem to be altered in schizophrenia. In previous work, we studied the spatial distribution of a noise power measure (scalp-recorded electroencephalographic activity unlocked to stimuli) and found higher magnitudes in the gamma band related to symptoms and c...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Suazo V,Lubeiro A,Jurado-Barba R,Moreno-Ortega M,Dompablo M,Morales-Muñoz I,Rodriguez-Jimenez R,Palomo T,Molina V

更新日期：2016-12-01 00:00:00

abstract：:Mutations in the presenilin-1 gene (PS-1 gene) on chromosome 14 have recently been identified as a cause of familial early-onset Alzheimer's disease (EOAD). To our knowledge, only two German EOAD patients with mutations in the PS-1 gene have been identified thus far. Herein we report the case of a German EOAD patient ...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Hüll M,Fiebich BL,Dykierek P,Schmidtke K,Nitzsche E,Orszagh M,Deuschl G,Moser E,Schumacher M,Lücking C,Berger M,Bauer J

更新日期：1998-01-01 00:00:00

abstract：:Abnormalities in fronto-limbic-striatal white matter (WM) have been reported in bipolar disorder (BD), but results have been inconsistent across studies. Furthermore, there have been no detailed investigations as to whether acute mood states contribute to microstructural changes in WM tracts. In order to compare fiber...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Zanetti MV,Jackowski MP,Versace A,Almeida JR,Hassel S,Duran FL,Busatto GF,Kupfer DJ,Phillips ML

更新日期：2009-09-01 00:00:00

abstract：:Changes in the surface morphology of the orbitofrontal cortex (OFC), such as a fewer orbital sulci and altered sulcogyral pattern of the 'H-shaped' orbital sulcus, have been reported in schizophrenia, possibly reflecting abnormal neurodevelopment during gestation. However, whether high-risk subjects for developing psy...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Nakamura M,Takahashi T,Takayanagi Y,Sasabayashi D,Katagiri N,Sakuma A,Obara C,Koike S,Yamasue H,Furuichi A,Kido M,Nishikawa Y,Noguchi K,Matsumoto K,Mizuno M,Kasai K,Suzuki M

更新日期：2019-06-01 00:00:00

abstract：:Clinical and neurobiological findings have reported the involvement of endocannabinoid signaling in the pathophysiology of schizophrenia. This system modulates dopaminergic and glutamatergic neurotransmission that is associated with positive, negative, and cognitive symptoms of schizophrenia. Despite neurotransmitter ...

journal_title：European archives of psychiatry and clinical neuroscience

authors： de Almeida V,Martins-de-Souza D

更新日期：2018-10-01 00:00:00

abstract：OBJECTIVE:Interpersonal psychotherapy (IPT) is a time-limited psychotherapy for major depression. The aim of this study is to summarize findings from controlled trials of the efficacy of IPT in the treatment of depressive spectrum disorders (DSD) using a meta-analytic approach. METHODS:Studies of randomized clinical t...

journal_title：European archives of psychiatry and clinical neuroscience

authors： de Mello MF,de Jesus Mari J,Bacaltchuk J,Verdeli H,Neugebauer R

更新日期：2005-04-01 00:00:00

abstract：:This report presents the rationale and design of a multi-center clinical trial that examines the efficacy and safety of antipsychotic combination treatment in acutely ill schizophrenia patients compared to antipsychotic monotherapy. Antipsychotic combination treatment is common in clinical practice worldwide, despite ...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Schmidt-Kraepelin C,Feyerabend S,Engelke C,Riesbeck M,Meisenzahl-Lechner E,Gaebel W,Verde PE,Kolbe H,Correll CU,Leucht S,Heres S,Kluge M,Makiol C,Neff A,Lange C,Englisch S,Zink M,Langguth B,Poeppl T,Reske D,Gouzou

更新日期：2020-02-01 00:00:00

abstract：:The Neuregulin (NRG1) gene has been associated with schizophrenia, but its functional implications are largely unknown. Our aim was to assess differential brain activation between patients carrying an at-risk allele on the Neuregulin 1 gene and patients without this genetic risk. Neural signal changes between 14 first...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Kircher T,Thienel R,Wagner M,Reske M,Habel U,Kellermann T,Frommann I,Schwab S,Wölwer W,von Wilmsdorf M,Braus DF,Schmitt A,Rapp A,Stöcker T,Shah NJ,Henn FA,Sauer H,Gaebel W,Maier W,Schneider F

更新日期：2009-03-01 00:00:00

abstract：:We have recorded postural performance in 50 HIV-infected patients in different stages of the disease (Walter Reed (WR) stages I-VI) by means of a force measuring platform. The results were compared with 50 age-matched controls. A significant instability was particularly evident when standing on an unstable foot suppor...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Trenkwalder C,Straube A,Paulus W,Krafczyk S,Schielke E,Einhäupl KM

更新日期：1992-01-01 00:00:00

abstract：:Evidence-based medicine (EBM) is becoming the guiding principle for clinical treatment decisions. But evidence remains a loosely defined term. Multiple criteria for evidence criteria have been proposed. Most influential evidence criteria give priority to meta-analyses because they promise an objective procedure to com...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Maier W,Möller HJ

更新日期：2010-02-01 00:00:00

abstract：:Research on emotional expression in adult schizophrenia patients has indicated an impairment of the patients' facial expressions during social interaction. However, it is unclear whether schizophrenia adolescent-onset patients show comparable disturbances in facial expression. Our aim was to analyze facial emotions in...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Lotzin A,Haack-Dees B,Resch F,Romer G,Ramsauer B

更新日期：2013-09-01 00:00:00

abstract：:The purpose of this article is to encourage research investigating the role of measured gene-environment interaction (G x E) in the etiology of posttraumatic stress disorder (PTSD). PTSD is uniquely suited to the study of G x E as the diagnosis requires exposure to a potentially-traumatic life event. PTSD is also mode...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Koenen KC,Nugent NR,Amstadter AB

更新日期：2008-03-01 00:00:00

abstract：:Some studies suggest seasonality of suicide attempts in females, but not in males. The reasons for this gender difference remain unclear. Only few studies addressed the question whether gender differences in seasonality of suicide attempts reflect gender differences in the choice of method for suicide attempts, with i...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Mergl R,Havers I,Althaus D,Rihmer Z,Schmidtke A,Lehfeld H,Niklewski G,Hegerl U

更新日期：2010-08-01 00:00:00

abstract：:The transcription nuclear factor-erythroid factor 2-related factor 2 (Nrf2) plays a key role in inflammation that is involved in depression. We previously reported that Nrf2 knock-out (KO) mice exhibit depression-like phenotypes through systemic inflammation. (R)-ketamine, an enantiomer of ketamine, has rapid-acting a...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Qu Y,Shan J,Wang S,Chang L,Pu Y,Wang X,Tan Y,Yamamoto M,Hashimoto K

更新日期：2020-11-12 00:00:00

abstract：:Although classical and atypical antipsychotics may have different neurotoxic effects, their underlying mechanisms remain to be elucidated, especially regarding neuroglial function. In the present study, we compared the atypical antipsychotic risperidone (0.01-10 μM) with the typical antipsychotic haloperidol (0.01-10 ...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Quincozes-Santos A,Bobermin LD,Tonial RP,Bambini-Junior V,Riesgo R,Gottfried C

更新日期：2010-09-01 00:00:00

abstract：:To date, few studies have addressed the relationship between brain structure alterations and responses to atypical antipsychotics in schizophrenia. To this end, in this study, magnetic resonance imaging (MRI) and voxel-based morphometry (VBM) were used to assess the relationship between the brain volumes of gray (GM) ...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Molina V,Martín C,Ballesteros A,de Herrera AG,Hernández-Tamames JA

更新日期：2011-09-01 00:00:00

abstract：:We studied 259 female inpatients with bipolar spectrum disorders, of whom 26 (10%) were schizoaffective. Of the remaining 233, 61 (27%) met our conservatively set criteria for index mixed episodes (simultaneous presence of depressive and manic syndromes). These patients with rigorously defined mixed states were, in tu...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Dell'Osso L,Akiskal HS,Freer P,Barberi M,Placidi GF,Cassano GB

更新日期：1993-01-01 00:00:00

abstract：:Our previous study has found that a long duration of untreated prodromal symptoms (DUPrS) does not increase the conversion risk to psychosis in individuals with attenuated psychosis syndrome (APS). However, whether a long DUPrS will lead to other poor outcomes remains unknown. The purpose of this study was to analyse ...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Zhang T,Xu L,Tang Y,Cui H,Tang X,Wei Y,Wang Y,Hu Q,Qian Z,Liu X,Li C,Wang J

更新日期：2019-12-01 00:00:00

abstract：:Schizophrenia is a severe neuropsychiatric disease that is associated with neurobiological alterations in multiple brain regions and peripheral organs. Negative symptoms and cognitive deficits are present in about half of patients and are difficult to treat, leading to an unfavorable functional outcome. To investigate...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Maurus I,Hasan A,Röh A,Takahashi S,Rauchmann B,Keeser D,Malchow B,Schmitt A,Falkai P

更新日期：2019-08-01 00:00:00

abstract：OBJECTIVES:The present study aims to assess the factor structure of the DSM-IV Premenstrual Dysphoric Disorder (PMDD) symptoms and its relationship with depressive symptoms. METHODS:We evaluated retrospectively PMDD symptoms in 513 female college students, through a self-reporting questionnaire based on DSM-IV criteri...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Teng CT,Filho AH,Artes R,Gorenstein C,Andrade LH,Wang YP

更新日期：2005-02-01 00:00:00

abstract：:Although cognitive behavioral therapy (CBT) is highly effective in the treatment of anxiety disorders, many patients still do not benefit. This study investigates whether a history of traumatic event experience is negatively associated with outcomes of CBT for panic disorder. The moderating role of the monoamine oxida...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Trautmann S,Richter J,Muehlhan M,Höfler M,Wittchen HU,Domschke K,Ströhle A,Hamm AO,Weber H,Kircher T,Arolt V,Gerlach AL,Alpers GW,Fydrich T,Lang T,Reif A

更新日期：2019-03-01 00:00:00

abstract：:DTNBP1 is one of the most established susceptibility genes for schizophrenia, and hippocampal volume reduction is one of the major neuropathological findings in this severe disorder. Consistent with these findings, the encoded protein dysbindin-1 has been shown to be diminished in glutamatergic hippocampal neurons in ...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Trost S,Platz B,Usher J,Scherk H,Wobrock T,Ekawardhani S,Meyer J,Reith W,Falkai P,Gruber O

更新日期：2013-02-01 00:00:00

abstract：OBJECTIVE:We tested Kraepelin's dichotomy model by studying the separability of schizophrenia and depression on the basis of symptoms and illness course. MATERIALS AND METHODS:Matched untreated patients with schizophrenia and depression (n = 130 each) and 130 "healthy" controls were assessed from onset to first admiss...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Häfner H,an der Heiden W,Maurer K

更新日期：2008-06-01 00:00:00

abstract：:Cerebrospinal fluid acetylcholinesterase (CSF AChE) was determined for elderly delirious patients during the acute stage and after a 1- and 4-year follow-up periods, and the AChE levels were compared with age-equivalent controls. The AChE levels measured during the index admission correlated with the length of life af...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Koponen HJ,Sirviö J,Lepola U,Leinonen E,Riekkinen PJ

更新日期：1994-01-01 00:00:00

abstract：:This 4-6-year prospective follow-up study compared reactive depressives with (n = 48) and without suicide attempts before index admission (n = 24). Both groups showed a favourable course and outcome concerning psychiatric diagnoses (DSM-III), psychopathology, social integration, and social functioning as well as displ...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Bronisch T,Hecht H

更新日期：1992-01-01 00:00:00

abstract：:Eating disorders and, in particular, anorexia nervosa (AN) have morbidity and mortality rates that are among the highest of any mental disorders and are associated with significant functional impairment. More than 25 years ago, several researchers hypothesised that the prerequisite for the development of AN was a fami...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Herpertz-Dahlmann B,Seitz J,Konrad K

更新日期：2011-11-01 00:00:00

abstract：:The objective of this study is to determine whether cannabis influences BDNF levels in patients with psychosis (FEP) and healthy volunteers (HV) to help understand the role of BDNF in psychosis. We assessed the association between BDNF and cannabis in a cohort of FEP antipsychotic-naïve patients and HV, whilst control...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Toll A,Bergé D,Burling K,Scoriels L,Treen D,Monserrat C,Marmol F,Duran X,Jones PB,Pérez-Solà V,Fernandez-Egea E,Mané A

更新日期：2020-10-01 00:00:00

abstract：:The novel coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The escalating number of SARS-CoV-2-infected individuals has conferred the viral spread with the status of global pandemic. However, there are no prophylactic or therapeutic drugs available on the m...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Hashimoto K

更新日期：2021-01-05 00:00:00

abstract：:The description of the heterogeneous phenomenological, pathophysiological, and etiological nature of schizophrenia is under way; however, the relationships between heterogeneity levels are still unclear. We performed a robust cross-sectional study, including a systematic neuropsychological battery, assessment of clini...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Szendi I,Racsmány M,Cimmer C,Csifcsák G,Kovács ZA,Szekeres G,Galsi G,Tóth F,Nagy A,Garab EA,Boda K,Gulyás G,Kiss JG,Dombi J,Pléh C,Janka Z

更新日期：2010-04-01 00:00:00