Postural imbalance: an early sign in HIV-1 infected patients.

Abstract:

:We have recorded postural performance in 50 HIV-infected patients in different stages of the disease (Walter Reed (WR) stages I-VI) by means of a force measuring platform. The results were compared with 50 age-matched controls. A significant instability was particularly evident when standing on an unstable foot support. In patients standing with "eyes closed", postural sway was significantly higher in every patient group (WR I-II: P less than 0.02, WR III-V: P less than 0.001, WR VI: P less than 0.001). Patients in stage WR I-II showed no relevant neurological abnormalities. In agreement with other neurophysiological data in the literature we suggest that postural imbalance could be an early sign of central nervous system penetration of HIV. No correlation with electromyographic or cerebrospinal fluid findings could be found.

authors

Trenkwalder C,Straube A,Paulus W,Krafczyk S,Schielke E,Einhäupl KM

doi

10.1007/BF02195975

subject

Has Abstract

pub_date

1992-01-01 00:00:00

pages

267-72

issue

5

eissn

0940-1334

issn

1433-8491

journal_volume

241

pub_type

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