Review: treatment of schizophrenia. State of the art.

abstract：:Two sisters with muscular dystrophy of Becker-like clinical features presented. Muscle weakness was most prominent in the pelvic girdle, but in the elder sister the distal muscles of the lower extremities were also affected. The progression was different in the siblings: The older sister showed a more pronounced deter...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Diószeghy P,Molnár M,Mechler F

更新日期：1995-01-01 00:00:00

abstract：:Mutations in the presenilin-1 gene (PS-1 gene) on chromosome 14 have recently been identified as a cause of familial early-onset Alzheimer's disease (EOAD). To our knowledge, only two German EOAD patients with mutations in the PS-1 gene have been identified thus far. Herein we report the case of a German EOAD patient ...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Hüll M,Fiebich BL,Dykierek P,Schmidtke K,Nitzsche E,Orszagh M,Deuschl G,Moser E,Schumacher M,Lücking C,Berger M,Bauer J

更新日期：1998-01-01 00:00:00

abstract：:The alpha 1C subunit of the L-type voltage-gated calcium channel (CACNA1C) gene is one of the best replicated susceptibility loci for bipolar disorder, schizophrenia and major depression. It is involved in learning, memory and brain plasticity. Genetic studies using functional magnetic resonance imaging (fMRI) reporte...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Krug A,Witt SH,Backes H,Dietsche B,Nieratschker V,Shah NJ,Nöthen MM,Rietschel M,Kircher T

更新日期：2014-03-01 00:00:00

abstract：:Visually scored and power spectral analyses (PSA) of polysomnography (PSG) recordings reveal abnormalities in alcohol dependence (AD) and major depressive disorder (MDD), including deficiencies in slow wave activity (SWA) during non-rapid eye movement (NREM) sleep. SWA parameters reflect the integrity of the homeostat...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Brower KJ,Hoffmann R,Conroy DA,Arnedt JT,Armitage R

更新日期：2011-12-01 00:00:00

abstract：OBJECTIVE:The aims of this study are threefold: to depict characteristics of homeless at discharge from a psychiatric hospital; to describe the utilisation of inpatient care and treatment measures during hospitalisation; and to analyse to what extent psychiatric disorders and clinical variables contribute to the risk f...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Lauber C,Lay B,Rössler W

更新日期：2006-04-01 00:00:00

abstract：:The aim of the study was to explore whether the individual burden of ADHD is the same in the elderly as in younger ages even though the symptomatological impact of ADHD seems to remain stable over the lifespan. To assess ADHD symptoms and ADHD-associated problems in daily life, standardised questionnaires were conduct...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Philipp-Wiegmann F,Retz-Junginger P,Retz W,Rösler M

更新日期：2016-06-01 00:00:00

abstract：:This study aims to investigate the relationship between regional connectivity in the brain white matter and the presence of psychotic personality traits, in healthy subjects with psychotic traits. Thirteen healthy controls were administered the MMPI-2, to assess psychotic traits and, according to MMPI results, a dicho...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Volpe U,Federspiel A,Mucci A,Dierks T,Frank A,Wahlund LO,Galderisi S,Maj M

更新日期：2008-08-01 00:00:00

abstract：:Five cases of acute pandysautonomia and one case of acute autonomic and sensory neuropathy are described with special reference to psychiatric symptoms. They originally presented as psychiatric disorders, such as hysterical neurosis, epilepsy, anorexia nervosa and hypochondriacal neurosis. Psychiatric symptoms arise f...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Okada F

更新日期：1990-01-01 00:00:00

abstract：:Despite clues indicating high Bullying at the Work Place (BWP) rates in French hospitals, there has been no quantitative study so far. To determine the prevalence of repeated BWP in a national sample of French young physicians; its risk factors, and the mental health consequences of BWP. The study is a cross-sectional...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Messiaen M,Duba A,Boulangeat C,Boucekine M,Bourbon A,Viprey M,Auquier P,Lançon C,Boyer L,Fond G

更新日期：2020-05-27 00:00:00

abstract：AIM:This study examined the extent to which fathers' and infants' interaction behavior were related to children's externalizing behavior problems at age 8 and 11 years. METHODS:In a prospective longitudinal study of children at risk for later psychopathology, 72 fathers and their 3-month-old children were videotaped a...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Trautmann-Villalba P,Gschwendt M,Schmidt MH,Laucht M

更新日期：2006-09-01 00:00:00

abstract：BACKGROUND:Only few studies have investigated executive impairment in the euthymic phase of unipolar affective disorders, yielding diverging results. The role of impulsivity/orbitofrontal associated executive functioning in remitted depression has not yet been examined. METHODS:Partly remitted male out-patients (n = 1...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Westheide J,Wagner M,Quednow BB,Hoppe C,Cooper-Mahkorn D,Strater B,Maier W,Kuhn KU

更新日期：2007-10-01 00:00:00

abstract：:Oral cenesthopathy is a somatic delusion or hallucination involving the oral area and is categorized as a delusional disorder, somatic type. The pathophysiology of this intractable condition remains obscure. In this study, we clarified the pathophysiology of oral cenesthopathy by evaluating regional brain perfusion. W...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Umezaki Y,Katagiri A,Watanabe M,Takenoshita M,Sakuma T,Sako E,Sato Y,Toriihara A,Uezato A,Shibuya H,Nishikawa T,Motomura H,Toyofuku A

更新日期：2013-06-01 00:00:00

abstract：:Obsessive-compulsive symptoms (OCS) in patients with schizophrenia are a common co-occurring condition, often associated with additional impairments. A subgroup of these patients develops OCS during treatment with second-generation antipsychotics (SGAs), most importantly clozapine and olanzapine. So far, little is kno...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Mier D,Schirmbeck F,Stoessel G,Esslinger C,Rausch F,Englisch S,Eisenacher S,de Haan L,Meyer-Lindenberg A,Kirsch P,Zink M

更新日期：2019-12-01 00:00:00

abstract：:While impairments in executive functions have been well established in major depressive disorder (MDD), specific deficits in proactive control have scarcely been studied so far. Proactive control refers to cognitive processes during anticipation of a behaviorally relevant event that facilitate readiness to react. In t...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Hoffmann A,Ettinger U,Montoro C,Reyes Del Paso GA,Duschek S

更新日期：2019-10-01 00:00:00

abstract：:Family history and psychosocial background factors were studied in married patients with a DSM-III diagnosis of schizoaffective disorder (n = 17, partners n = 16), married patients with diabetes (n = 10, partners n = 10) and married healthy individuals (n = 8, partners n = 8). The two latter groups were comparison con...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Nettelbladt P,Svensson C,Serin U

更新日期：1996-01-01 00:00:00

abstract：:The relationship between lateral ventricular size or its asymmetry and age at the onset of schizophrenia was investigated in 20 schizophrenic patients diagnosed according to DSM-III-R criteria. The ventricle-brain ratio (VBR) was determined using three transaxial slices of magnetic resonance image (MRI) and asymmetry ...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Aso M,Kurachi M,Suzuki M,Yuasa S,Matsui M,Saitoh O

更新日期：1995-01-01 00:00:00

abstract：:Early life maltreatment (ELM) has long-lasting effects on social interaction. When interacting with their own child, women with ELM often report difficulties in parenting and show reduced maternal sensitivity. Sensitive maternal behavior requires the recognition of the child's emotional state depicted in its facial em...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Neukel C,Herpertz SC,Hinid-Attar C,Zietlow AL,Fuchs A,Moehler E,Bermpohl F,Bertsch K

更新日期：2019-03-01 00:00:00

abstract：:The purpose of this article is to encourage research investigating the role of measured gene-environment interaction (G x E) in the etiology of posttraumatic stress disorder (PTSD). PTSD is uniquely suited to the study of G x E as the diagnosis requires exposure to a potentially-traumatic life event. PTSD is also mode...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Koenen KC,Nugent NR,Amstadter AB

更新日期：2008-03-01 00:00:00

abstract：:DTNBP1 is one of the most established susceptibility genes for schizophrenia, and hippocampal volume reduction is one of the major neuropathological findings in this severe disorder. Consistent with these findings, the encoded protein dysbindin-1 has been shown to be diminished in glutamatergic hippocampal neurons in ...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Trost S,Platz B,Usher J,Scherk H,Wobrock T,Ekawardhani S,Meyer J,Reith W,Falkai P,Gruber O

更新日期：2013-02-01 00:00:00

abstract：:Impairments in emotion recognition and psychosocial functioning are a robust phenomenon in schizophrenia and may affect motivational behavior, particularly during socio-emotional interactions. To characterize potential deficits and their interplay, we assessed social motivation covering various facets, such as implici...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Radke S,Pfersmann V,Derntl B

更新日期：2015-10-01 00:00:00

abstract：:The efficacy of aripiprazole therapy and the risk of adverse reactions are influenced by substantial inter-individual variability in aripiprazole metabolizing capacity. In vitro studies assigned the potential role in aripiprazole metabolism to CYP2D6 and CYP3A enzymes; therefore, the association between the steady-sta...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Kiss Á,Menus Á,Tóth K,Déri M,Sirok D,Gabri E,Belic A,Csukly G,Bitter I,Monostory K

更新日期：2020-02-01 00:00:00

abstract：:Compounds targeting serotonin (5-HT) are widely used as antidepressants. However, the role of 5-HT in mediating the effects of electroconvulsive seizure (ECS) therapy remains undefined. Using Tph2-/- mice depleted of brain 5-HT, we studied the effects of ECS on behavior and neurobiology. ECS significantly prolonged th...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Kronenberg G,Petermann M,Dormann C,Bader M,Gass P,Hellweg R,Klempin F

更新日期：2018-12-01 00:00:00

abstract：:Ego-disturbances (passivity phenomena) and formal thought disorder are two hallmark symptoms of schizophrenia. Formal thought disorder has been highlighted already very early by Eugen Bleuler in his concept of basic symptoms (Grundsymptome). In contrast ego-disturbances (Ich-Störungen) or passivity phenomena have been...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Leube D,Whitney C,Kircher T

更新日期：2008-11-01 00:00:00

abstract：:To assess the course of neuropsychological (NP) impairment in schizophrenia, 71 patients with first episode (FE) schizophrenia and 71 healthy controls were given a comprehensive battery of NP tests at index assessment, after a 2-year and after a 5-year follow-up period. By means of the z-score standardization, summary...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Albus M,Hubmann W,Mohr F,Hecht S,Hinterberger-Weber P,Seitz NN,Küchenhoff H

更新日期：2006-10-01 00:00:00

abstract：:This report presents the rationale and design of a multi-center clinical trial that examines the efficacy and safety of antipsychotic combination treatment in acutely ill schizophrenia patients compared to antipsychotic monotherapy. Antipsychotic combination treatment is common in clinical practice worldwide, despite ...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Schmidt-Kraepelin C,Feyerabend S,Engelke C,Riesbeck M,Meisenzahl-Lechner E,Gaebel W,Verde PE,Kolbe H,Correll CU,Leucht S,Heres S,Kluge M,Makiol C,Neff A,Lange C,Englisch S,Zink M,Langguth B,Poeppl T,Reske D,Gouzou

更新日期：2020-02-01 00:00:00

abstract：:This European Psychiatric Association (EPA) guidance paper is a result of the Working Group on Mental Health Consequences of Economic Crises of the EPA Council of National Psychiatric Associations. Its purpose is to identify the impact on mental health in Europe of the economic downturn and the measures that may be ta...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Martin-Carrasco M,Evans-Lacko S,Dom G,Christodoulou NG,Samochowiec J,González-Fraile E,Bienkowski P,Gómez-Beneyto M,Dos Santos MJ,Wasserman D

更新日期：2016-03-01 00:00:00

abstract：:To improve recognition and treatment of depression in primary care it would be advantageous to have criteria for identification of later depression. Only a few studies were performed on primary care samples to examine risk factors for new depressive episodes. These were mostly cross-sectional and did not include psych...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Barkow K,Heun R,Ustün TB,Maier W

更新日期：2001-01-01 00:00:00

abstract：:All operationalized diagnostic systems contain a diagnostic category, which corresponds to the concept of major depression. Yet, these corresponding definitions are not identical. Up to now, no comprehensive comparisons of the competing diagnoses have been published. We will therefore present a series of studies, desc...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Philipp M,Maier W,Delmo CD

更新日期：1991-01-01 00:00:00

abstract：:Posttraumatic stress disorder (PTSD) has been associated with an altered processing of threat-related stimuli. In particular, an attentional bias towards threat cues has been consistently found in behavioral studies. However, it is unclear whether increased attention towards threat cues translates into preferential pr...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Catani C,Adenauer H,Keil J,Aichinger H,Neuner F

更新日期：2009-09-01 00:00:00

abstract：:Attention deficit and hyperactivity disorder (ADHD) is a prevalent childhood disorder that is often maintained throughout the development and persists into adulthood. Established etiology models suggest that deficient inhibition underlies the core ADHD symptoms. While experimental evidence for impaired motor inhibitio...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Jusyte A,Zaretskaya N,Höhnle NM,Bartels A,Schönenberg M

更新日期：2018-06-01 00:00:00