Brain serotonin critically contributes to the biological effects of electroconvulsive seizures.

abstract：:The Trial Criteria in Schizophrenia Working Group was convened in November 2007 to define consensus criteria for clinical trials in patients suffering from acute schizophrenia with special focus on placebo-controlled trials and withdrawal conditions. Clinical trials involving patients give rise to ethical and medico-l...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Riedel M,Leucht S,Rüther E,Schmauß M,Möller HJ

更新日期：2012-03-01 00:00:00

abstract：AIM:This study examined the extent to which fathers' and infants' interaction behavior were related to children's externalizing behavior problems at age 8 and 11 years. METHODS:In a prospective longitudinal study of children at risk for later psychopathology, 72 fathers and their 3-month-old children were videotaped a...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Trautmann-Villalba P,Gschwendt M,Schmidt MH,Laucht M

更新日期：2006-09-01 00:00:00

abstract：:Our previous study has found that a long duration of untreated prodromal symptoms (DUPrS) does not increase the conversion risk to psychosis in individuals with attenuated psychosis syndrome (APS). However, whether a long DUPrS will lead to other poor outcomes remains unknown. The purpose of this study was to analyse ...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Zhang T,Xu L,Tang Y,Cui H,Tang X,Wei Y,Wang Y,Hu Q,Qian Z,Liu X,Li C,Wang J

更新日期：2019-12-01 00:00:00

abstract：:Obstetric complications play a role in the pathophysiology of schizophrenia. However, the biological consequences during neurodevelopment until adulthood are unknown. Microarrays have been used for expression profiling in four brain regions of a rat model of neonatal hypoxia as a common factor of obstetric complicatio...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Sommer JU,Schmitt A,Heck M,Schaeffer EL,Fendt M,Zink M,Nieselt K,Symons S,Petroianu G,Lex A,Herrera-Marschitz M,Spanagel R,Falkai P,Gebicke-Haerter PJ

更新日期：2010-11-01 00:00:00

abstract：:The course of obsessive-compulsive disorder (OCD) is variable, ranging from episodic to chronic. We hypothesised that the former course is more likely to be related to bipolar mood disorders. With the use of a specially constructed OCD questionnaire, we studied 135 patients fulfilling DSM-III-R criteria for OCD with a...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Perugi G,Akiskal HS,Gemignani A,Pfanner C,Presta S,Milanfranchi A,Lensi P,Ravagli S,Maremmani I,Cassano GB

更新日期：1998-01-01 00:00:00

abstract：:Abnormalities in fronto-limbic-striatal white matter (WM) have been reported in bipolar disorder (BD), but results have been inconsistent across studies. Furthermore, there have been no detailed investigations as to whether acute mood states contribute to microstructural changes in WM tracts. In order to compare fiber...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Zanetti MV,Jackowski MP,Versace A,Almeida JR,Hassel S,Duran FL,Busatto GF,Kupfer DJ,Phillips ML

更新日期：2009-09-01 00:00:00

abstract：:Cognitive impairment is one of the core symptoms of schizophrenia. Multiple domains of cognition are affected in patients with schizophrenia, which has a major effect on the functional outcome. Recent studies indicate that SNPs in the gamma-aminobutyric acid type A receptor beta 2 subunit (GABRB2) gene are associated ...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Zhang Q,Zhang X,Song S,Wang S,Wang X,Yu H,Han H,Zhou X,Li G,Wu Y

更新日期：2020-06-01 00:00:00

abstract：:Our social activity is heavily influenced by the process of introspection, with emerging research suggesting a role for the Default Mode Network (DMN) in social cognition. We hypothesize that oxytocin, a neuropeptide with an important role in social behaviour, can effectively alter the connectivity of the DMN. We test...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Kumar J,Iwabuchi SJ,Völlm BA,Palaniyappan L

更新日期：2020-08-01 00:00:00

abstract：:The purpose of this article is to encourage research investigating the role of measured gene-environment interaction (G x E) in the etiology of posttraumatic stress disorder (PTSD). PTSD is uniquely suited to the study of G x E as the diagnosis requires exposure to a potentially-traumatic life event. PTSD is also mode...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Koenen KC,Nugent NR,Amstadter AB

更新日期：2008-03-01 00:00:00

abstract：:Smartphone applications ("apps") may contribute to closing the treatment gap for depression by reaching large populations at relatively low costs. The general public seems open towards the use of apps for mental disorders but less is known about the attitudes of health care professionals. Therefore, the aim of this st...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Kerst A,Zielasek J,Gaebel W

更新日期：2020-03-01 00:00:00

abstract：:Accelerated repetitive transcranial magnetic stimulation (rTMS) protocols are being increasingly studied because of their potential to provide quicker and enhanced treatment efficacy. However, there is a lack of accelerated deep TMS with H1-coil (adTMS) treatment research. This randomized pilot study investigated the ...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Filipčić I,Šimunović Filipčić I,Sučić S,Milovac Ž,Gereš N,Matić K,Čelić-Ružić M,Zečević Penić S,Orgulan I,Požgaj V,Bajić Ž

更新日期：2020-05-24 00:00:00

abstract：:This article systematically reviews the literature on the outcome of acute hospitalization for adult general psychiatric patients admitted involuntarily as compared to patients admitted voluntarily. Inclusion and exclusion criteria qualified 41 out of 3,227 references found in Medline and PSYNDEXplus literature search...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Kallert TW,Glöckner M,Schützwohl M

更新日期：2008-06-01 00:00:00

abstract：:The National Institute on Aging-Alzheimer's Association (NIA-AA) clinical research criteria for mild cognitive impairment (MCI) due to Alzheimer's disease (AD) incorporate the use of biomarkers to classify patients according to the likelihood of the presence of AD pathology. The aim of the study was to compare the ris...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Guo LH,Alexopoulos P,Eisele T,Wagenpfeil S,Kurz A,Perneczky R

更新日期：2013-06-01 00:00:00

abstract：:Evidence suggests that the anterior cingulate cortex (ACC) plays a key role in the development of posttraumatic stress disorder (PTSD). Owing to the region's highly variable patterns, three different studies of PTSD have yielded inconsistent volume reductions. Accordingly, in order to measure the correct borders and v...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Jatzko A,Vogler C,Demirakca T,Ruf M,Malchow B,Falkai P,Braus DF,Ende G,Schmitt A

更新日期：2013-10-01 00:00:00

abstract：:Various factors contribute to the development and maintenance of delusions in the context of schizophrenic psychoses. Studies with functional and structural MRI were able to detect neurobiological correlates of paranoid symptoms. Consistent with the neurodevelopmental hypothesis of schizophrenic psychosis, which impli...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Knobel A,Heinz A,Voss M

更新日期：2008-11-01 00:00:00

abstract：:Clinical and neurobiological findings have reported the involvement of endocannabinoid signaling in the pathophysiology of schizophrenia. This system modulates dopaminergic and glutamatergic neurotransmission that is associated with positive, negative, and cognitive symptoms of schizophrenia. Despite neurotransmitter ...

journal_title：European archives of psychiatry and clinical neuroscience

authors： de Almeida V,Martins-de-Souza D

更新日期：2018-10-01 00:00:00

abstract：:Low social integration is commonly described in acutely suicidal individuals. Neural mechanisms underlying low social integration are poorly understood in depressed and suicidal patients. We sought to characterize the neural response to low social integration in acutely suicidal patients. Adult depressed patients with...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Cáceda R,James GA,Stowe ZN,Delgado PL,Kordsmeier N,Kilts CD

更新日期：2020-08-01 00:00:00

abstract：:Preventive endeavours in psychotic disorders have been hampered by many obstacles over the past century. One important barrier has been the corrosive pessimism which has attached to the treatment prospects for schizophrenia in particular since the time of Kraepelin, and the isolation of this disorder from progressive ...

journal_title：European archives of psychiatry and clinical neuroscience

authors： McGorry PD

更新日期：1998-01-01 00:00:00

abstract：OBJECTIVE:This exploratory study aims to compare lifetime psychiatric axis-I-comorbidity and psychosocial functioning in a clinically referred sample of adult patients with attention-deficit/hyperactivity disorder (ADHD) with a population-based healthy control group and to examine whether patients with ADHD and lifetim...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Sobanski E,Brüggemann D,Alm B,Kern S,Deschner M,Schubert T,Philipsen A,Rietschel M

更新日期：2007-10-01 00:00:00

abstract：:A summarised account is given of Emil Kraepelin's research in the field of mental disorder, underlining his emphasis on objectivity and natural science and the need for a multi-disciplinary approach. At the same time attention is drawn to the limitations of his general outlook and to his political views, which in thei...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Shepherd M

更新日期：1995-01-01 00:00:00

abstract：:Intravascular lymphomatosis (IVL), a rare type of non-Hodgkin's lymphoma, is an uncommon cause of progressive dementia, usually followed by death within a few months of onset of clinical disease. Often this aggressive tumor is only diagnosed at autopsy, because of misleading clinical features mimicking a broad spectru...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Albrecht R,Krebs B,Reusche E,Nagel M,Lencer R,Kretzschmar HA

更新日期：2005-08-01 00:00:00

abstract：:Overactive performance monitoring has been consistently reported in obsessive-compulsive disorder (OCD). OCD is a clinically heterogeneous disorder and is characterized by several symptom dimensions that may have partially distinct neural correlates. We examined whether performance-monitoring alterations are related t...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Riesel A,Kathmann N,Endrass T

更新日期：2014-12-01 00:00:00

abstract：:Depressive disorders are influenced by a complex interplay between genetic and environmental factors. Multiple studies support a role of serotonergic pathways in the pathophysiology of depressive disorders. As a rate-limiting enzyme of serotonin synthesis in the brain, tryptophan hydroxylase 2 (TPH2) represents a plau...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Van der Auwera S,Janowitz D,Schulz A,Homuth G,Nauck M,Völzke H,Rose M,Meyer zu Schwabedissen H,Freyberger HJ,Grabe HJ

更新日期：2014-11-01 00:00:00

abstract：:Cerebrospinal fluid acetylcholinesterase (CSF AChE) was determined for elderly delirious patients during the acute stage and after a 1- and 4-year follow-up periods, and the AChE levels were compared with age-equivalent controls. The AChE levels measured during the index admission correlated with the length of life af...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Koponen HJ,Sirviö J,Lepola U,Leinonen E,Riekkinen PJ

更新日期：1994-01-01 00:00:00

abstract：:Quality indicators are vital for monitoring the transformation of institution-based mental health services towards the provision of person-centered mental healthcare. While several mental healthcare quality indicators have been identified as relevant and valid, their actual usability and utility for routine monitoring...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Gaebel W,Lehmann I,Chisholm D,Hinkov H,Höschl C,Kapócs G,Kurimay T,Tosevski DL,Milosavljevic M,Nakov V,Winkler P,Zielasek J

更新日期：2020-04-08 00:00:00

abstract：:Suicide is a tremendous threat to global public health, and a large number of people who committed suicide suffered the pain of mental diseases, especially major depressive disorder (MDD). Previous study showed that ketamine could reduce suicidal ideation (SI), potentially by improving the impaired working memory (WM)...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Chen X,Wang M,Hu Y,Zhan Y,Zhou Y,Zheng W,Liu W,Wang C,Zhong X,Li H,Lan X,Ning Y,Zhang B

更新日期：2021-01-01 00:00:00

abstract：:Three groups of married women were studied with each defined by their experience of a different stressful incident (the target event). In the first (the Coronary Group), the husband had suffered a non-fatal myocardial infarction whilst in the second (the Bereaved Group), he had recently died. In the third (the Refuge ...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Miller PM,Surtees PG

更新日期：1993-01-01 00:00:00

abstract：:Refractory psychosis units currently have little information regarding which symptoms profiles should be expected to respond to treatment. In the current study, we provide this information using structural equation modeling of Positive and Negative Syndrome Scale (PANSS) ratings at admission and discharge on a sample ...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Woodward TS,Jung K,Smith GN,Hwang H,Barr AM,Procyshyn RM,Flynn SW,van der Gaag M,Honer WG

更新日期：2014-12-01 00:00:00

abstract：OBJECTIVE:Risk factors, emergence and accumulation of symptoms in the untreated early course were studied as a basis for understanding the relationship between schizophrenia and depression. MATERIALS AND METHODS:130 representative first admissions for schizophrenia were compared retrospectively with 130 individually m...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Häfner H,Maurer K,Trendler G,an der Heiden W,Schmidt M

更新日期：2005-06-01 00:00:00

abstract：:Dopamine D(2) blocking typical antipsychotic drugs are known to change the cerebral perfusion patterns of schizophrenic patients, especially in the frontal cortex and basal ganglia. In recent years atypical antipsychotics such as olanzapine, which have high serotonin 5-HT(2A)/dopamine D(2) occupation ratios, have been...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Gonul AS,Kula M,Sofuoglu S,Tutus A,Esel E

更新日期：2003-02-01 00:00:00