Interaction among childhood trauma and functional polymorphisms in the serotonin pathway moderate the risk of depressive disorders.

abstract：BACKGROUND:This placebo-controlled study was designed to investigate the influence of two different stimulation procedures of repetitive transcranial magnetic stimulation (rTMS) on depressive symptoms in patients with depressive disorders. Furthermore, effects on cognitive functions and psychomotor functioning were tes...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Höppner J,Schulz M,Irmisch G,Mau R,Schläfke D,Richter J

更新日期：2003-04-01 00:00:00

abstract：:Our social activity is heavily influenced by the process of introspection, with emerging research suggesting a role for the Default Mode Network (DMN) in social cognition. We hypothesize that oxytocin, a neuropeptide with an important role in social behaviour, can effectively alter the connectivity of the DMN. We test...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Kumar J,Iwabuchi SJ,Völlm BA,Palaniyappan L

更新日期：2020-08-01 00:00:00

abstract：:Cognitive models suggest that top-down and emotional processes increase false perceptions in schizophrenia spectrum disorders (SSD). However, little is still known about the interaction of these processes in false auditory perceptions. The present study aimed at investigating the specific as well as joint impacts of e...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Gawęda Ł,Moritz S

更新日期：2019-09-06 00:00:00

abstract：:Abnormalities in fronto-limbic-striatal white matter (WM) have been reported in bipolar disorder (BD), but results have been inconsistent across studies. Furthermore, there have been no detailed investigations as to whether acute mood states contribute to microstructural changes in WM tracts. In order to compare fiber...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Zanetti MV,Jackowski MP,Versace A,Almeida JR,Hassel S,Duran FL,Busatto GF,Kupfer DJ,Phillips ML

更新日期：2009-09-01 00:00:00

abstract：:Substance P-like and somatostatin-like immunoreactivities (SPLI and SLI) were determined in ventricular fluid of patients with chronic pain syndromes and in a comparison group with multiple sclerosis, essential tremor, epilepsy and postanoxic myoclonus. Concentrations of SPLI and SLI were non-significantly decreased b...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Jost S,Reuner C,Geiger J,Mohadjer M,Milios E,Cramer H

更新日期：1991-01-01 00:00:00

abstract：:MAOA and, to a lesser extent, MAOB polymorphisms have been related to aggression traits and suicidality. We aimed to investigate the role of MAOA and MAOB in suicidal versus non-suicidal participants and interactions between genetic variation and suicidal status on aggression and anger-related traits. The sample was c...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Antypa N,Giegling I,Calati R,Schneider B,Hartmann AM,Friedl M,Konte B,Lia L,De Ronchi D,Serretti A,Rujescu D

更新日期：2013-08-01 00:00:00

abstract：:Scientific progress fostered in DSM and ICD over the past quarter of century has significantly increased awareness of the limitation of categorical definitions of mental illness. Disorders highly merge into another with no natural boundary in between. The addition of continuous, "dimensional" measures into the various...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Okasha A

更新日期：2009-11-01 00:00:00

abstract：:The efficacy of aripiprazole therapy and the risk of adverse reactions are influenced by substantial inter-individual variability in aripiprazole metabolizing capacity. In vitro studies assigned the potential role in aripiprazole metabolism to CYP2D6 and CYP3A enzymes; therefore, the association between the steady-sta...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Kiss Á,Menus Á,Tóth K,Déri M,Sirok D,Gabri E,Belic A,Csukly G,Bitter I,Monostory K

更新日期：2020-02-01 00:00:00

abstract：:Refsum's disease (Heredopathia atactica polyneuritiformis) is caused by accumulation of phytanic acid in all body tissues due to an inherited failure of alpha-oxidation of branched chain fatty acids. Plasmapheresis has been reported to be beneficial by removal of phytanic acid from the blood. We describe a patient wit...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Leppert D,Schanz U,Burger J,Gmür J,Blau N,Waespe W

更新日期：1991-01-01 00:00:00

abstract：:Dopamine D(2) blocking typical antipsychotic drugs are known to change the cerebral perfusion patterns of schizophrenic patients, especially in the frontal cortex and basal ganglia. In recent years atypical antipsychotics such as olanzapine, which have high serotonin 5-HT(2A)/dopamine D(2) occupation ratios, have been...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Gonul AS,Kula M,Sofuoglu S,Tutus A,Esel E

更新日期：2003-02-01 00:00:00

abstract：:Auditory verbal hallucinations (AH) are core symptoms of schizophrenia. They are often severely distressing and refractory to therapy. Their perception is associated with increased activity in temporoparietal areas of the brain. Repetitive transcranial magnetic stimulation (rTMS) can reduce focal brain hyperactivity a...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Plewnia C,Brendel B,Schwippel T,Martus P,Cordes J,Hasan A,Fallgatter AJ

更新日期：2018-10-01 00:00:00

abstract：:Antisocial personality disorder is characterized by a stable, lifelong pattern of disregard for and violation of others' rights. Disruptions in the representation of fairness norms may represent a key mechanism in the development and maintenance of this disorder. Here, we investigated fairness norm considerations and ...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Mayer SV,Rauss K,Pourtois G,Jusyte A,Schönenberg M

更新日期：2019-09-01 00:00:00

abstract：:Advances in psychopathological research advocate a personality-centred model of common mental disorders (CMD). We tested four hypotheses to test such a model. First, personality relates to critical life events; second, both personality and critical life events relate to CMD; third, interaction effects between personal...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Hengartner MP,Tyrer P,Ajdacic-Gross V,Angst J,Rössler W

更新日期：2018-08-01 00:00:00

abstract：:The impact of obsessive-compulsive symptoms on functioning in schizophrenia is still debated. This study investigated the relationship between OC symptoms and functioning along a severity gradient of obsessive-compulsive dimension. Sixty patients affected by schizophrenia completed the SCID-IV, the Positive and Negati...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Tonna M,Ottoni R,Paglia F,Ossola P,De Panfilis C,Marchesi C

更新日期：2016-02-01 00:00:00

abstract：:A group of 52 patients presenting at an outpatient unit for anxiety disorders were included consecutively in a prospective 2-year follow-up study. Patients were administered to a structured interview for DSM-III-R diagnoses, a follow-up interview (LIFE), and various other ratings. Sociodemographic and illness-history ...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Scheibe G,Albus M

更新日期：1994-01-01 00:00:00

abstract：:Impairments in emotion recognition and psychosocial functioning are a robust phenomenon in schizophrenia and may affect motivational behavior, particularly during socio-emotional interactions. To characterize potential deficits and their interplay, we assessed social motivation covering various facets, such as implici...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Radke S,Pfersmann V,Derntl B

更新日期：2015-10-01 00:00:00

abstract：:Attention deficit and hyperactivity disorder (ADHD) is a prevalent childhood disorder that is often maintained throughout the development and persists into adulthood. Established etiology models suggest that deficient inhibition underlies the core ADHD symptoms. While experimental evidence for impaired motor inhibitio...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Jusyte A,Zaretskaya N,Höhnle NM,Bartels A,Schönenberg M

更新日期：2018-06-01 00:00:00

abstract：:Altered neuroplasticity contributes to the pathophysiology of schizophrenia. However, the idea that antipsychotics may act, at least in part, by normalizing neurogenesis has not been consistently supported. Our study seeks to determine whether hippocampal cell proliferation is altered in adult rats pretreated with ket...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Keilhoff G,Grecksch G,Bernstein HG,Roskoden T,Becker A

更新日期：2010-03-01 00:00:00

abstract：BACKGROUND:Knowledge about psychopathologic presentations of mania in current clinical practice has to be refined in order to improve diagnosis and treatment. METHODS:One thousand ninety manic patients included in the French National Study EPIMAN-II Mille were submitted to a cluster analysis on the basis of multiple v...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Azorin JM,Kaladjian A,Adida M,Hantouche E,Hameg A,Lancrenon S,Akiskal HS

更新日期：2008-12-01 00:00:00

abstract：:The conceptualization of rapidly cycling bipolar disorder remains controversial. The DSM-IV definition of rapid cycling, although very reliable, may be not sufficiently inclusive (i.e., it may exclude patients with very short episodes of very high frequency, who are very typical in terms of external validators, and ar...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Maj M

更新日期：2001-01-01 00:00:00

abstract：:Recent transcranial sonography (TCS) studies showed that disruption of echogenic midbrain line, corresponding to basal limbic system and raphe nuclei (RN) within, might represent functional marker for the development of depression. Major depressive disorder (MDD) is one of the most common psychiatric disorders associa...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Budisic M,Karlovic D,Trkanjec Z,Lovrencic-Huzjan A,Vukovic V,Bosnjak J,Demarin V

更新日期：2010-04-01 00:00:00

abstract：:Knowledge on the reliability of family history information is essential for every family study. However, systematic analyses of interinformant reliability of family history information on individual relatives have not yet been published. Consequently, family history information on 1306 first-degree relatives and spous...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Heun R,Müller H

更新日期：1998-01-01 00:00:00

abstract：:Diagnostic checklists for the assessment of DSM-III-R Axis I diagnoses have proven to be a reliable and feasible instrument in research and routine clinical care. Therefore, a checklist for the assessment of the DSM-III-R Personality Disorders (MDCL-P) has been developed. An English version of the MDCL-P is available....

journal_title：European archives of psychiatry and clinical neuroscience

authors： Bronisch T,Garcia-Borreguero D,Flett S,Wolf R,Hiller W

更新日期：1992-01-01 00:00:00

abstract：OBJECTIVE:Childhood traumatic experiences, rearing styles, familial mental disorders and birth risk factors have been associated with the development of social anxiety disorder. METHOD:Patients with social anxiety disorder (n=50) and healthy controls (n=120) were investigated using a retrospective interview with 203 q...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Bandelow B,Charimo Torrente A,Wedekind D,Broocks A,Hajak G,Rüther E

更新日期：2004-12-01 00:00:00

abstract：BACKGROUND:Only few studies have investigated executive impairment in the euthymic phase of unipolar affective disorders, yielding diverging results. The role of impulsivity/orbitofrontal associated executive functioning in remitted depression has not yet been examined. METHODS:Partly remitted male out-patients (n = 1...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Westheide J,Wagner M,Quednow BB,Hoppe C,Cooper-Mahkorn D,Strater B,Maier W,Kuhn KU

更新日期：2007-10-01 00:00:00

abstract：:We studied 259 female inpatients with bipolar spectrum disorders, of whom 26 (10%) were schizoaffective. Of the remaining 233, 61 (27%) met our conservatively set criteria for index mixed episodes (simultaneous presence of depressive and manic syndromes). These patients with rigorously defined mixed states were, in tu...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Dell'Osso L,Akiskal HS,Freer P,Barberi M,Placidi GF,Cassano GB

更新日期：1993-01-01 00:00:00

abstract：:A consensus group consisting of 36 experts representing 20 leading German specialist societies and patient self-help organizations developed evidence-based recommendations for the treatment of anxiety disorders in Germany. These were based on a systematic review of randomized controlled trials on anxiety disorders (n ...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Bandelow B,Lichte T,Rudolf S,Wiltink J,Beutel ME

更新日期：2015-08-01 00:00:00

abstract：:Low social integration is commonly described in acutely suicidal individuals. Neural mechanisms underlying low social integration are poorly understood in depressed and suicidal patients. We sought to characterize the neural response to low social integration in acutely suicidal patients. Adult depressed patients with...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Cáceda R,James GA,Stowe ZN,Delgado PL,Kordsmeier N,Kilts CD

更新日期：2020-08-01 00:00:00

abstract：:Five cases of acute pandysautonomia and one case of acute autonomic and sensory neuropathy are described with special reference to psychiatric symptoms. They originally presented as psychiatric disorders, such as hysterical neurosis, epilepsy, anorexia nervosa and hypochondriacal neurosis. Psychiatric symptoms arise f...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Okada F

更新日期：1990-01-01 00:00:00

abstract：:Despite the lack of clinical data about the role of the endocannabinoid system (ECS) in affective disorders, preclinical work suggests that the ECS is relevant in both with regard to the etiology of depression as well as the mediation of antidepressant effects. We measured the intraindividual levels of the endocannabi...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Kranaster L,Hoyer C,Aksay SS,Bumb JM,Leweke FM,Janke C,Thiel M,Lutz B,Bindila L,Sartorius A

更新日期：2017-12-01 00:00:00