Signs of rapidly progressive dementia in a case of intravascular lymphomatosis.

Abstract:

:Intravascular lymphomatosis (IVL), a rare type of non-Hodgkin's lymphoma, is an uncommon cause of progressive dementia, usually followed by death within a few months of onset of clinical disease. Often this aggressive tumor is only diagnosed at autopsy, because of misleading clinical features mimicking a broad spectrum of syndromes and the absence of circulating lympoma cells in the blood, bone marrow or cerebrospinal fluid in many cases. Here we present IVL in a 78-year-old woman with findings leading to the clinical diagnosis of vascular dementia with sudden beginning and positive 14-3-3 protein in the CSF, commonly reported in Creutzfeldt-Jakob disease (CJD).

authors

Albrecht R,Krebs B,Reusche E,Nagel M,Lencer R,Kretzschmar HA

doi

10.1007/s00406-004-0551-9

subject

Has Abstract

pub_date

2005-08-01 00:00:00

pages

232-5

issue

4

eissn

0940-1334

issn

1433-8491

journal_volume

255

pub_type

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