The cognitive, affective motivational and clinical longitudinal determinants of apathy in schizophrenia.

abstract：:Impairments in emotion recognition and psychosocial functioning are a robust phenomenon in schizophrenia and may affect motivational behavior, particularly during socio-emotional interactions. To characterize potential deficits and their interplay, we assessed social motivation covering various facets, such as implici...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Radke S,Pfersmann V,Derntl B

更新日期：2015-10-01 00:00:00

abstract：:Nocturnal sleep was studied in 14 human immunodeficiency virus (HIV)-positive patients without opportunistic infections of the central nervous system. Seven patients had no bodily complaints at the time of the investigation. Patients exhibited an impaired nocturnal sleep with longer sleep onset latency, reduced total ...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Wiegand M,Möller AA,Schreiber W,Krieg JC,Fuchs D,Wachter H,Holsboer F

更新日期：1991-01-01 00:00:00

abstract：:The relationship between lateral ventricular size or its asymmetry and age at the onset of schizophrenia was investigated in 20 schizophrenic patients diagnosed according to DSM-III-R criteria. The ventricle-brain ratio (VBR) was determined using three transaxial slices of magnetic resonance image (MRI) and asymmetry ...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Aso M,Kurachi M,Suzuki M,Yuasa S,Matsui M,Saitoh O

更新日期：1995-01-01 00:00:00

abstract：:Although cognitive behavioral therapy (CBT) is highly effective in the treatment of anxiety disorders, many patients still do not benefit. This study investigates whether a history of traumatic event experience is negatively associated with outcomes of CBT for panic disorder. The moderating role of the monoamine oxida...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Trautmann S,Richter J,Muehlhan M,Höfler M,Wittchen HU,Domschke K,Ströhle A,Hamm AO,Weber H,Kircher T,Arolt V,Gerlach AL,Alpers GW,Fydrich T,Lang T,Reif A

更新日期：2019-03-01 00:00:00

abstract：UNLABELLED:Patients with somatoform pain often complain of sleep disorders, but sleep disorders are not an integrated part of the diagnosis of this disorder. Restless legs syndrome is associated with painful symptoms and sleep disturbances. The aim of our study was to evaluate the prevalence of restless legs syndrome (...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Aigner M,Prause W,Freidl M,Weiss M,Izadi S,Bach M,Saletu B

更新日期：2007-02-01 00:00:00

abstract：:Protein expression of VGF (nonacronymic) is induced by nerve/brain-derived growth factor, neurotrophin 3, and insulin. VGF is synthesized by neurons in the paraventricular (PVN) and supraoptic (SON) nuclei of the hypothalamus. After enzymatic processing, smaller VGF-derived peptides are secreted into the cerebrospinal...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Busse S,Bernstein HG,Busse M,Bielau H,Brisch R,Mawrin C,Müller S,Sarnyai Z,Gos T,Bogerts B,Steiner J

更新日期：2012-08-01 00:00:00

abstract：:Posttraumatic stress disorder (PTSD) has been associated with an altered processing of threat-related stimuli. In particular, an attentional bias towards threat cues has been consistently found in behavioral studies. However, it is unclear whether increased attention towards threat cues translates into preferential pr...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Catani C,Adenauer H,Keil J,Aichinger H,Neuner F

更新日期：2009-09-01 00:00:00

abstract：:Compounds targeting serotonin (5-HT) are widely used as antidepressants. However, the role of 5-HT in mediating the effects of electroconvulsive seizure (ECS) therapy remains undefined. Using Tph2-/- mice depleted of brain 5-HT, we studied the effects of ECS on behavior and neurobiology. ECS significantly prolonged th...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Kronenberg G,Petermann M,Dormann C,Bader M,Gass P,Hellweg R,Klempin F

更新日期：2018-12-01 00:00:00

abstract：:The impact of obsessive-compulsive symptoms on functioning in schizophrenia is still debated. This study investigated the relationship between OC symptoms and functioning along a severity gradient of obsessive-compulsive dimension. Sixty patients affected by schizophrenia completed the SCID-IV, the Positive and Negati...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Tonna M,Ottoni R,Paglia F,Ossola P,De Panfilis C,Marchesi C

更新日期：2016-02-01 00:00:00

abstract：:Obsessive-compulsive symptoms (OCS) are frequently reported in patients with schizophrenia and have been associated with subjective distress and higher impairment. Recent studies suggest fluctuation in co-occurring OCS and associations with the course of psychotic symptoms. Current evidence is limited by few studies w...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Schirmbeck F,Konijn M,Hoetjes V,Zink M,de Haan L,For Genetic Risk and Outcome of Psychosis (GROUP).

更新日期：2019-03-01 00:00:00

abstract：:The aim of this study was to evaluate residual symptoms in patients achieving remission according to the consensus criteria and to analyze their potential influence on the patient's outcome one year after discharge. In total, 399 patients suffering from a schizophrenia spectrum disorder were evaluated within a natural...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Schennach R,Riedel M,Obermeier M,Spellmann I,Musil R,Jäger M,Schmauss M,Laux G,Pfeiffer H,Naber D,Schmidt LG,Gaebel W,Klosterkötter J,Heuser I,Maier W,Lemke MR,Rüther E,Klingberg S,Gastpar M,Möller HJ

更新日期：2015-03-01 00:00:00

abstract：:An involvement of the central serotonergic system has constantly been reported in the pathogenesis of suicide. The dorsal raphe nucleus (DRN) is the main source of serotonergic innervation of forebrain limbic structures disturbed in suicidal behaviour, in which an abnormal microglia reaction seems to play a role. In o...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Brisch R,Steiner J,Mawrin C,Krzyżanowska M,Jankowski Z,Gos T

更新日期：2017-08-01 00:00:00

abstract：:A group of 52 patients presenting at an outpatient unit for anxiety disorders were included consecutively in a prospective 2-year follow-up study. Patients were administered to a structured interview for DSM-III-R diagnoses, a follow-up interview (LIFE), and various other ratings. Sociodemographic and illness-history ...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Scheibe G,Albus M

更新日期：1994-01-01 00:00:00

abstract：:The aim of this study was to estimate the prevalence and incidence of mood disorders, anxiety disorders, and stress and adjustment disorders in primary health care in Sweden and to analyse the relationship between socioeconomic and demographic factors and incidence of these disorders. Prevalence and incidence data on ...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Lejtzén N,Sundquist J,Sundquist K,Li X

更新日期：2014-04-01 00:00:00

abstract：:A follow-up and family study was carried out of 16 first episode, DSM-III-R schizophreniform disorder patients with good prognostic features. Mean length of follow-up was 52.3 months. It was found that 62.5% had affective episodes, 31.2% had schizophreniform episodes. No case of schizophrenia was observed. Outcome was...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Benazzi F,Mazzoli M,Rossi E

更新日期：1992-01-01 00:00:00

abstract：:During a course of electroconvulsive therapy (ECT), the level of currency necessary to induce an epileptic seizure in a patient may either remain relatively stable or-more often-may require repeated upward adjustment over time due to a constantly increasing seizure threshold. We aimed to determine whether a common pol...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Stephani C,Shoukier M,Ahmed R,Wolff-Menzler C

更新日期：2017-12-01 00:00:00

abstract：:Abnormalities in fronto-limbic-striatal white matter (WM) have been reported in bipolar disorder (BD), but results have been inconsistent across studies. Furthermore, there have been no detailed investigations as to whether acute mood states contribute to microstructural changes in WM tracts. In order to compare fiber...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Zanetti MV,Jackowski MP,Versace A,Almeida JR,Hassel S,Duran FL,Busatto GF,Kupfer DJ,Phillips ML

更新日期：2009-09-01 00:00:00

abstract：:Recent transcranial sonography (TCS) studies showed that disruption of echogenic midbrain line, corresponding to basal limbic system and raphe nuclei (RN) within, might represent functional marker for the development of depression. Major depressive disorder (MDD) is one of the most common psychiatric disorders associa...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Budisic M,Karlovic D,Trkanjec Z,Lovrencic-Huzjan A,Vukovic V,Bosnjak J,Demarin V

更新日期：2010-04-01 00:00:00

abstract：:MAOA and, to a lesser extent, MAOB polymorphisms have been related to aggression traits and suicidality. We aimed to investigate the role of MAOA and MAOB in suicidal versus non-suicidal participants and interactions between genetic variation and suicidal status on aggression and anger-related traits. The sample was c...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Antypa N,Giegling I,Calati R,Schneider B,Hartmann AM,Friedl M,Konte B,Lia L,De Ronchi D,Serretti A,Rujescu D

更新日期：2013-08-01 00:00:00

abstract：:A significant comorbidity between attention-deficit/hyperactivity disorder (ADHD) and affective disorders has been consistently reported in adults. Less data regarding the role of personality traits and the influence of ADHD co-occurrence on clinical characteristics and outcome of mood disorders are currently availabl...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Di Nicola M,Sala L,Romo L,Catalano V,Even C,Dubertret C,Martinotti G,Camardese G,Mazza M,Tedeschi D,Callea A,De Risio L,Guelfi JD,Rouillon F,Janiri L,Gorwood P

更新日期：2014-08-01 00:00:00

abstract：:Our social activity is heavily influenced by the process of introspection, with emerging research suggesting a role for the Default Mode Network (DMN) in social cognition. We hypothesize that oxytocin, a neuropeptide with an important role in social behaviour, can effectively alter the connectivity of the DMN. We test...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Kumar J,Iwabuchi SJ,Völlm BA,Palaniyappan L

更新日期：2020-08-01 00:00:00

abstract：:Bipolar disorder (BD) has been associated with a proinflammatory state in which TNF-α seems to play a relevant role. The aim of the present study was to evaluate the plasma levels of TNF-α and its soluble receptors (sTNFR1 and sTNFR2) in BD patients in mania and euthymia in comparison with control subjects. We evaluat...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Barbosa IG,Huguet RB,Mendonça VA,Sousa LP,Neves FS,Bauer ME,Teixeira AL

更新日期：2011-03-01 00:00:00

abstract：:The alpha 1C subunit of the L-type voltage-gated calcium channel (CACNA1C) gene is one of the best replicated susceptibility loci for bipolar disorder, schizophrenia and major depression. It is involved in learning, memory and brain plasticity. Genetic studies using functional magnetic resonance imaging (fMRI) reporte...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Krug A,Witt SH,Backes H,Dietsche B,Nieratschker V,Shah NJ,Nöthen MM,Rietschel M,Kircher T

更新日期：2014-03-01 00:00:00

abstract：:Increases in seizure threshold (ST) over a course of brief pulse ECT can be predicted by decreases in EEG quality, informing ECT dose adjustment to maintain adequate supra-threshold dosing. ST increases also occur over a course of right unilateral ultrabrief (RUL UB) ECT, but no data exist on the relationship between ...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Gálvez V,Hadzi-Pavlovic D,Waite S,Loo CK

更新日期：2017-12-01 00:00:00

abstract：:Minority religions, sects and cults are an increasingly common socio-cultural phenomenon, of which the effects concerning mental health and illness are still poorly understood. In the present study, we compared socio-demographical and clinical characteristics between members of Christian sects and the remaining genera...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Dalgalarrondo P,Lotz M

更新日期：1993-01-01 00:00:00

abstract：OBJECTIVE:This exploratory study aims to compare lifetime psychiatric axis-I-comorbidity and psychosocial functioning in a clinically referred sample of adult patients with attention-deficit/hyperactivity disorder (ADHD) with a population-based healthy control group and to examine whether patients with ADHD and lifetim...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Sobanski E,Brüggemann D,Alm B,Kern S,Deschner M,Schubert T,Philipsen A,Rietschel M

更新日期：2007-10-01 00:00:00

abstract：OBJECTIVE:The study of familial aggregation of major mental disorders in a national population. METHOD:Within a Danish register-based cohort study, aggregation of mental disorders was analysed in all case-probands with first psychiatric contact before the age of 19 years in the time period between 1 April 1969 and 29 ...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Steinhausen HC,Foldager L,Perto G,Munk-Jørgensen P

更新日期：2009-08-01 00:00:00

abstract：:Based on the original data from two double-blind, randomized, placebo-controlled clinical trials and the acute phase of a long-term study that investigated the antidepressant efficacy of St. John's wort extract WS 5570, we present a re-analysis of a subset of patients suffering from an acute episode of mild depression...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Kasper S,Gastpar M,Müller WE,Volz HP,Dienel A,Kieser M,Möller HJ

更新日期：2008-02-01 00:00:00

abstract：:The present article outlines the different conception of catatonia from its initial description by Kahlbaum to current viewpoints. Originally considered to be an independent disease entity characterized by mental and motor abnormalities, catatonia was later viewed as a subtype of schizophrenia as it is the case in cur...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Pfuhlmann B,Stöber G

更新日期：2001-01-01 00:00:00

abstract：OBJECTIVE:Risk factors, emergence and accumulation of symptoms in the untreated early course were studied as a basis for understanding the relationship between schizophrenia and depression. MATERIALS AND METHODS:130 representative first admissions for schizophrenia were compared retrospectively with 130 individually m...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Häfner H,Maurer K,Trendler G,an der Heiden W,Schmidt M

更新日期：2005-06-01 00:00:00