A follow-up and family study of DSM-III-R schizophreniform disorder with good prognostic features.

abstract：:Event-related potentials (ERPs) can serve as markers for cognitive processing stages. Identification of those ERPs altered in schizophrenia offer information about cognitive dysfunction. Auditory evoked potentials (AEPs) were elicited within an oddball paradigm in 35 schizophrenic patients and compared with 35 healthy...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Frodl T,Meisenzahl EM,Gallinat J,Hegerl U,Möller HJ

更新日期：1998-01-01 00:00:00

abstract：:The aim of this study was to investigate theory of mind (ToM) ability in patients in remission after the first episode of schizophrenia. A ToM task which contained four pictures was given to 30 patients with schizophrenia in remission and 30 matched healthy controls. Patients with schizophrenia in remission showed sta...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Inoue Y,Yamada K,Hirano M,Shinohara M,Tamaoki T,Iguchi H,Tonooka Y,Kanba S

更新日期：2006-08-01 00:00:00

abstract：:Schizophrenia has been linked to disturbed connectivity between large-scale brain networks. Altered thalamocortical connectivity might be a major mechanism mediating regionally distributed dysfunction, yet it is only incompletely understood. We analysed functional magnetic resonance imaging data obtained during restin...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Klingner CM,Langbein K,Dietzek M,Smesny S,Witte OW,Sauer H,Nenadic I

更新日期：2014-03-01 00:00:00

abstract：:In a recent randomized, double-blind, placebo-controlled trial, we established a robust efficacy (Cohen's d = 2.17) of osmotic release oral system-methylphenidate (OROS-methylphenidate) delivered 72 mg daily for 5 weeks versus placebo on attention deficit hyperactivity disorder (ADHD) symptoms, global severity and glo...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Ginsberg Y,Hirvikoski T,Grann M,Lindefors N

更新日期：2012-12-01 00:00:00

abstract：:Physical activity is a common adjunctive therapy in psychiatric and psychosomatic hospitals. In the present study, we assessed the effects of an exercise program, integrated into routine inpatient treatment, on cognitive performance and subjective severity of depression in a sample of patients suffering from major dep...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Buschert V,Prochazka D,Bartl H,Diemer J,Malchow B,Zwanzger P,Brunnauer A

更新日期：2019-08-01 00:00:00

abstract：:Three groups of married women were studied with each defined by their experience of a different stressful incident (the target event). In the first (the Coronary Group), the husband had suffered a non-fatal myocardial infarction whilst in the second (the Bereaved Group), he had recently died. In the third (the Refuge ...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Miller PM,Surtees PG

更新日期：1993-01-01 00:00:00

abstract：:Preventive endeavours in psychotic disorders have been hampered by many obstacles over the past century. One important barrier has been the corrosive pessimism which has attached to the treatment prospects for schizophrenia in particular since the time of Kraepelin, and the isolation of this disorder from progressive ...

journal_title：European archives of psychiatry and clinical neuroscience

authors： McGorry PD

更新日期：1998-01-01 00:00:00

abstract：:Gamma oscillations are key in coordinating brain activity and seem to be altered in schizophrenia. In previous work, we studied the spatial distribution of a noise power measure (scalp-recorded electroencephalographic activity unlocked to stimuli) and found higher magnitudes in the gamma band related to symptoms and c...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Suazo V,Lubeiro A,Jurado-Barba R,Moreno-Ortega M,Dompablo M,Morales-Muñoz I,Rodriguez-Jimenez R,Palomo T,Molina V

更新日期：2016-12-01 00:00:00

abstract：:To assess the course of neuropsychological (NP) impairment in schizophrenia, 71 patients with first episode (FE) schizophrenia and 71 healthy controls were given a comprehensive battery of NP tests at index assessment, after a 2-year and after a 5-year follow-up period. By means of the z-score standardization, summary...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Albus M,Hubmann W,Mohr F,Hecht S,Hinterberger-Weber P,Seitz NN,Küchenhoff H

更新日期：2006-10-01 00:00:00

abstract：:Obstetric complications play a role in the pathophysiology of schizophrenia. However, the biological consequences during neurodevelopment until adulthood are unknown. Microarrays have been used for expression profiling in four brain regions of a rat model of neonatal hypoxia as a common factor of obstetric complicatio...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Sommer JU,Schmitt A,Heck M,Schaeffer EL,Fendt M,Zink M,Nieselt K,Symons S,Petroianu G,Lex A,Herrera-Marschitz M,Spanagel R,Falkai P,Gebicke-Haerter PJ

更新日期：2010-11-01 00:00:00

abstract：:Altered neuroplasticity contributes to the pathophysiology of schizophrenia. However, the idea that antipsychotics may act, at least in part, by normalizing neurogenesis has not been consistently supported. Our study seeks to determine whether hippocampal cell proliferation is altered in adult rats pretreated with ket...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Keilhoff G,Grecksch G,Bernstein HG,Roskoden T,Becker A

更新日期：2010-03-01 00:00:00

abstract：:Theoretical and empirical models of thought disorder (ThD) were tested through Confirmatory factor analysis (CFA). A sample of 253 DSM-III-R acute schizophrenic patients consecutively admitted was studied. A semistructured interview for schizophrenia was used for diagnosis, and ThD was assessed by means of the Thought...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Cuesta MJ,Peralta V

更新日期：1999-01-01 00:00:00

abstract：:All operationalized diagnostic systems contain a diagnostic category, which corresponds to the concept of major depression. Yet, these corresponding definitions are not identical. Up to now, no comprehensive comparisons of the competing diagnoses have been published. We will therefore present a series of studies, desc...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Philipp M,Maier W,Delmo CD

更新日期：1991-01-01 00:00:00

abstract：:DTNBP1 is one of the most established susceptibility genes for schizophrenia, and hippocampal volume reduction is one of the major neuropathological findings in this severe disorder. Consistent with these findings, the encoded protein dysbindin-1 has been shown to be diminished in glutamatergic hippocampal neurons in ...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Trost S,Platz B,Usher J,Scherk H,Wobrock T,Ekawardhani S,Meyer J,Reith W,Falkai P,Gruber O

更新日期：2013-02-01 00:00:00

abstract：:This study investigates the nosological specificity and time stability of reduced facial expressivity in schizophrenia by means of objective measurement. Facial expression in an emotional interview was evaluated using the "Facial Action Coding System" in 33 acute schizophrenia patients and 23 acute depressive patients...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Gaebel W,Wölwer W

更新日期：2004-10-01 00:00:00

abstract：:The Trial Criteria in Schizophrenia Working Group was convened in November 2007 to define consensus criteria for clinical trials in patients suffering from acute schizophrenia with special focus on placebo-controlled trials and withdrawal conditions. Clinical trials involving patients give rise to ethical and medico-l...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Riedel M,Leucht S,Rüther E,Schmauß M,Möller HJ

更新日期：2012-03-01 00:00:00

abstract：:In recent studies, the glutamate (Glu) level has been quantified using the modified STEAM sequence on 3T MRI. We enrolled 15 healthy volunteers and a group of 51 patients who experienced stroke for the first time and had a good prognosis. The patients with infarction were divided into three groups according to their s...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Wang X,Li YH,Li MH,Lu J,Zhao JG,Sun XJ,Zhang B,Ye JL

更新日期：2012-02-01 00:00:00

abstract：:The differential diagnosis of obsessive-compulsive disorder (OCD) and schizophrenia-spectrum disorders can be difficult. In the current diagnostic criteria, basic concepts such as obsession and delusion overlap. This study examined lifetime schizophrenia-spectrum psychopathology, including subtle schizotypal symptomat...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Rasmussen AR,Nordgaard J,Parnas J

更新日期：2020-12-01 00:00:00

abstract：OBJECTIVE:Interpersonal psychotherapy (IPT) is a time-limited psychotherapy for major depression. The aim of this study is to summarize findings from controlled trials of the efficacy of IPT in the treatment of depressive spectrum disorders (DSD) using a meta-analytic approach. METHODS:Studies of randomized clinical t...

journal_title：European archives of psychiatry and clinical neuroscience

authors： de Mello MF,de Jesus Mari J,Bacaltchuk J,Verdeli H,Neugebauer R

更新日期：2005-04-01 00:00:00

abstract：:Dopamine D(2) blocking typical antipsychotic drugs are known to change the cerebral perfusion patterns of schizophrenic patients, especially in the frontal cortex and basal ganglia. In recent years atypical antipsychotics such as olanzapine, which have high serotonin 5-HT(2A)/dopamine D(2) occupation ratios, have been...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Gonul AS,Kula M,Sofuoglu S,Tutus A,Esel E

更新日期：2003-02-01 00:00:00

abstract：:Clinical and neurobiological findings have reported the involvement of endocannabinoid signaling in the pathophysiology of schizophrenia. This system modulates dopaminergic and glutamatergic neurotransmission that is associated with positive, negative, and cognitive symptoms of schizophrenia. Despite neurotransmitter ...

journal_title：European archives of psychiatry and clinical neuroscience

authors： de Almeida V,Martins-de-Souza D

更新日期：2018-10-01 00:00:00

abstract：OBJECTIVE:Risk factors, emergence and accumulation of symptoms in the untreated early course were studied as a basis for understanding the relationship between schizophrenia and depression. MATERIALS AND METHODS:130 representative first admissions for schizophrenia were compared retrospectively with 130 individually m...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Häfner H,Maurer K,Trendler G,an der Heiden W,Schmidt M

更新日期：2005-06-01 00:00:00

abstract：:Compounds targeting serotonin (5-HT) are widely used as antidepressants. However, the role of 5-HT in mediating the effects of electroconvulsive seizure (ECS) therapy remains undefined. Using Tph2-/- mice depleted of brain 5-HT, we studied the effects of ECS on behavior and neurobiology. ECS significantly prolonged th...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Kronenberg G,Petermann M,Dormann C,Bader M,Gass P,Hellweg R,Klempin F

更新日期：2018-12-01 00:00:00

abstract：:Besides the ventral tegmental area and the nucleus accumbens as the most investigated brain reward structures, several reports about the relation between volume and activity of the amygdala and drug-seeking behavior have emphasized the central role of the amygdala in the etiology of addiction. Considering its proposed...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Zill P,Vielsmeier V,Büttner A,Eisenmenger W,Siedler F,Scheffer B,Möller HJ,Bondy B

更新日期：2011-03-01 00:00:00

abstract：:Comorbid disorders are common in psychiatric diseases and understanding the risk of secondary diseases can aid successful clinical treatment. The objective of this study was to compare the frequency of comorbid dementia, affective disorders, and inflammatory polyarthropathies. Healthcare data obtained via the German H...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Vogelgsang J,Heßmann P,Wolff-Menzler C,Gyßer S,Müller GA,Wiltfang J

更新日期：2020-03-01 00:00:00

abstract：:Five cases of acute pandysautonomia and one case of acute autonomic and sensory neuropathy are described with special reference to psychiatric symptoms. They originally presented as psychiatric disorders, such as hysterical neurosis, epilepsy, anorexia nervosa and hypochondriacal neurosis. Psychiatric symptoms arise f...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Okada F

更新日期：1990-01-01 00:00:00

abstract：:Abnormalities of the cerebellum and default-mode network (DMN) in patients with obsessive-compulsive disorder (OCD) have been widely reported. However, alterations of reciprocal functional connections between the cerebellum and DMN at rest in OCD remain unclear. Forty patients with OCD and 38 gender-, age-, and educat...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Lv D,Ou Y,Chen Y,Yang R,Zhong Z,Jia C,Sun L,Wang Y,Zhang G,Sun Z,Wang W,Wang Y,Wang X,Guo W,Li P

更新日期：2020-12-01 00:00:00

abstract：:Savoxepine, an atypical neuroleptic compound developed in the 1980s, was believed to act via selective limbic dopamine D(2)-receptor blockade. The results of the presented double-blind, randomised, controlled clinical trial comparing savoxepine (n = 58) with haloperidol (n = 29) did not confirm the preclinical data su...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Volz HP,Möller HJ,Gerebtzoff A,Bischoff S

更新日期：2002-04-01 00:00:00

abstract：:Oral cenesthopathy is a somatic delusion or hallucination involving the oral area and is categorized as a delusional disorder, somatic type. The pathophysiology of this intractable condition remains obscure. In this study, we clarified the pathophysiology of oral cenesthopathy by evaluating regional brain perfusion. W...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Umezaki Y,Katagiri A,Watanabe M,Takenoshita M,Sakuma T,Sako E,Sato Y,Toriihara A,Uezato A,Shibuya H,Nishikawa T,Motomura H,Toyofuku A

更新日期：2013-06-01 00:00:00

abstract：:The aim of this study was to reexamine and compare the characteristics of the deficit and nondeficit schizophrenic patients. This cross-sectional study consisted of 62 in- and out-patients, 18-65 years of age, diagnosed with schizophrenia according to DSM-IV. The sociodemographic variables, premorbid adjustment, clini...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Tiryaki A,Yazici MK,Anil AE,Kabakçi E,Karaağaoğlu E,Göğüş A

更新日期：2003-10-01 00:00:00