Markers from event-related potential subcomponents and reaction time for information processing dysfunction in schizophrenia.

abstract：:The efficacy of aripiprazole therapy and the risk of adverse reactions are influenced by substantial inter-individual variability in aripiprazole metabolizing capacity. In vitro studies assigned the potential role in aripiprazole metabolism to CYP2D6 and CYP3A enzymes; therefore, the association between the steady-sta...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Kiss Á,Menus Á,Tóth K,Déri M,Sirok D,Gabri E,Belic A,Csukly G,Bitter I,Monostory K

更新日期：2020-02-01 00:00:00

abstract：:Despite the lack of clinical data about the role of the endocannabinoid system (ECS) in affective disorders, preclinical work suggests that the ECS is relevant in both with regard to the etiology of depression as well as the mediation of antidepressant effects. We measured the intraindividual levels of the endocannabi...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Kranaster L,Hoyer C,Aksay SS,Bumb JM,Leweke FM,Janke C,Thiel M,Lutz B,Bindila L,Sartorius A

更新日期：2017-12-01 00:00:00

abstract：:Intoxicated persons showing challenging behavior (IPCBs) under influence of alcohol and/or drugs frequently have trouble finding appropriate acute care. Often IPCBs are stigmatized being unwilling or unable to accept help. Separated physical and mental healthcare systems hamper integrated acute care for IPCBs. This pi...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Verheesen SMH,Ten Doesschate F,van Schijndel MA,van der Gaag RJ,Cahn W,van Waarde JA

更新日期：2020-07-12 00:00:00

abstract：:Physical activity is a common adjunctive therapy in psychiatric and psychosomatic hospitals. In the present study, we assessed the effects of an exercise program, integrated into routine inpatient treatment, on cognitive performance and subjective severity of depression in a sample of patients suffering from major dep...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Buschert V,Prochazka D,Bartl H,Diemer J,Malchow B,Zwanzger P,Brunnauer A

更新日期：2019-08-01 00:00:00

abstract：:Cannabinoid receptors and their endogenous ligands have been detected from the earliest stages of embryonic development. The endocannabinoid system appears to play essential roles in these early stages for neuronal development and cell survival, although its detailed involvement in fundamental developmental processes ...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Schneider M

更新日期：2009-10-01 00:00:00

abstract：:Refractory psychosis units currently have little information regarding which symptoms profiles should be expected to respond to treatment. In the current study, we provide this information using structural equation modeling of Positive and Negative Syndrome Scale (PANSS) ratings at admission and discharge on a sample ...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Woodward TS,Jung K,Smith GN,Hwang H,Barr AM,Procyshyn RM,Flynn SW,van der Gaag M,Honer WG

更新日期：2014-12-01 00:00:00

abstract：:The impact of obsessive-compulsive symptoms on functioning in schizophrenia is still debated. This study investigated the relationship between OC symptoms and functioning along a severity gradient of obsessive-compulsive dimension. Sixty patients affected by schizophrenia completed the SCID-IV, the Positive and Negati...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Tonna M,Ottoni R,Paglia F,Ossola P,De Panfilis C,Marchesi C

更新日期：2016-02-01 00:00:00

abstract：:Intravascular lymphomatosis (IVL), a rare type of non-Hodgkin's lymphoma, is an uncommon cause of progressive dementia, usually followed by death within a few months of onset of clinical disease. Often this aggressive tumor is only diagnosed at autopsy, because of misleading clinical features mimicking a broad spectru...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Albrecht R,Krebs B,Reusche E,Nagel M,Lencer R,Kretzschmar HA

更新日期：2005-08-01 00:00:00

abstract：:The novel coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The escalating number of SARS-CoV-2-infected individuals has conferred the viral spread with the status of global pandemic. However, there are no prophylactic or therapeutic drugs available on the m...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Hashimoto K

更新日期：2021-01-05 00:00:00

abstract：:An international, multicentre, double blind parallel group study compared the tolerability and efficacy of moclobemide with the selective serotonin reuptake inhibitor (SSRI) fluoxetine for panic disorder. SSRIs have been shown effective for panic. The target dose of moclobemide was 450 mg and of fluoxetine was 20 mg. ...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Tiller JW,Bouwer C,Behnke K

更新日期：1999-01-01 00:00:00

abstract：:Emotional dysregulation (ED) is being increasingly recognized as a core feature of attention-deficit/hyperactivity disorder (ADHD), but the pathophysiological underpinnings remain unclear. In this study, we provide meaningful electrophysiological evidence of ED in adult patients with ADHD (n = 39) compared to healthy ...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Shushakova A,Ohrmann P,Pedersen A

更新日期：2018-06-01 00:00:00

abstract：:Obstetric complications play a role in the pathophysiology of schizophrenia. However, the biological consequences during neurodevelopment until adulthood are unknown. Microarrays have been used for expression profiling in four brain regions of a rat model of neonatal hypoxia as a common factor of obstetric complicatio...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Sommer JU,Schmitt A,Heck M,Schaeffer EL,Fendt M,Zink M,Nieselt K,Symons S,Petroianu G,Lex A,Herrera-Marschitz M,Spanagel R,Falkai P,Gebicke-Haerter PJ

更新日期：2010-11-01 00:00:00

abstract：:Scientific progress fostered in DSM and ICD over the past quarter of century has significantly increased awareness of the limitation of categorical definitions of mental illness. Disorders highly merge into another with no natural boundary in between. The addition of continuous, "dimensional" measures into the various...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Okasha A

更新日期：2009-11-01 00:00:00

abstract：:This report presents the rationale and design of a multi-center clinical trial that examines the efficacy and safety of antipsychotic combination treatment in acutely ill schizophrenia patients compared to antipsychotic monotherapy. Antipsychotic combination treatment is common in clinical practice worldwide, despite ...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Schmidt-Kraepelin C,Feyerabend S,Engelke C,Riesbeck M,Meisenzahl-Lechner E,Gaebel W,Verde PE,Kolbe H,Correll CU,Leucht S,Heres S,Kluge M,Makiol C,Neff A,Lange C,Englisch S,Zink M,Langguth B,Poeppl T,Reske D,Gouzou

更新日期：2020-02-01 00:00:00

abstract：:While the impact of mentally ill patients' perceptions of their key relatives' expressed emotion is well examined with regard to relapse, there is a paucity of evidence concerning the impact on their key relatives' burden. The present study aims to evaluate the relative prognostic value of expressed and perceived emot...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Möller-Leimkühler AM,Jandl M

更新日期：2011-08-01 00:00:00

abstract：:Low social integration is commonly described in acutely suicidal individuals. Neural mechanisms underlying low social integration are poorly understood in depressed and suicidal patients. We sought to characterize the neural response to low social integration in acutely suicidal patients. Adult depressed patients with...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Cáceda R,James GA,Stowe ZN,Delgado PL,Kordsmeier N,Kilts CD

更新日期：2020-08-01 00:00:00

abstract：:Complaints of sleep disturbances are common among alcohol dependent patients during subacute abstinence. Recovered patients may show persistent sleep abnormalities for months or even years. In the present study we studied the issue whether periodic limb movements in sleep and disturbances of nocturnal respiration are ...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Gann H,Feige B,Fasihi S,van Calker D,Voderholzer U,Riemann D

更新日期：2002-06-01 00:00:00

abstract：OBJECTIVE:Fluoxetine and its active metabolite norfluoxetine have long half-lives. We postulate that, owing to the long elimination half-life and the time to reach steady-state level in plasma is nearly four weeks, patients diagnosed with major depressive disorder might be treated with fluoxetine taken once every third...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Tural U,Onder E

更新日期：2003-12-01 00:00:00

abstract：:Besides the ventral tegmental area and the nucleus accumbens as the most investigated brain reward structures, several reports about the relation between volume and activity of the amygdala and drug-seeking behavior have emphasized the central role of the amygdala in the etiology of addiction. Considering its proposed...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Zill P,Vielsmeier V,Büttner A,Eisenmenger W,Siedler F,Scheffer B,Möller HJ,Bondy B

更新日期：2011-03-01 00:00:00

abstract：:Impairments in emotion recognition and psychosocial functioning are a robust phenomenon in schizophrenia and may affect motivational behavior, particularly during socio-emotional interactions. To characterize potential deficits and their interplay, we assessed social motivation covering various facets, such as implici...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Radke S,Pfersmann V,Derntl B

更新日期：2015-10-01 00:00:00

abstract：:Three adult schizophrenic patients without a previous history of epilepsy are reported who, during clozapine treatment, developed paroxysmal EEG patterns and generalized myoclonic jerks without alteration of consciousness. These seizures were phenomenologically identical to those occurring in juvenile myoclonic epilep...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Gouzoulis E,Grunze H,von Bardeleben U

更新日期：1991-01-01 00:00:00

abstract：:In clinical trials in psychiatry, changes in severity are usually measured with ordinal level scales which are applied repeatedly during the trial, showing a constant decline in psychopathology scores as treatment leads to improvement. Previous non-parametric tests for repeated measures in factorial designs did not te...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Bandelow B,Brunner E,Beinroth D,Pralle L,Broocks A,Hajak G,Rüther E

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND:Although a number of studies have reported on the association between obsessional personality features as measured by the Munich Personality Test (MPT) "Rigidity" scale and depression, there has been no examination of these relationships in a non-clinical sample. METHODS:The dimensional scores on the MPT we...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Sakado K,Sakado M,Seki T,Kuwabara H,Kojima M,Sato T,Someya T

更新日期：2001-06-01 00:00:00

abstract：:As a result of the multifactorial etiopathology of schizophrenia, a treatment strategy combining drug therapy with psychosocial measures is indicated. Depending on the stage of the disease and on the individual condition of the patient, the accent is set alternatively more on one approach or on the other. However, und...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Möller HJ

更新日期：1996-01-01 00:00:00

abstract：:This study aims to investigate the relationship between regional connectivity in the brain white matter and the presence of psychotic personality traits, in healthy subjects with psychotic traits. Thirteen healthy controls were administered the MMPI-2, to assess psychotic traits and, according to MMPI results, a dicho...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Volpe U,Federspiel A,Mucci A,Dierks T,Frank A,Wahlund LO,Galderisi S,Maj M

更新日期：2008-08-01 00:00:00

abstract：OBJECTIVE:Several predictors of Alzheimer's disease (AD) have been identified. However, the relevance and independent contribution of risk factors and of possible early signs such as mild cognitive impairment and subjective memory impairment on the development of AD has not been investigated prospectively in a cohort o...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Heun R,Kölsch H,Jessen F

更新日期：2006-02-01 00:00:00

abstract：:The Cognitive Behavioral Analysis System of Psychotherapy (CBASP) is a relatively new approach in the treatment of chronic depression (CD). Adapted as group psychotherapy for inpatients, CBASP is attracting increasing attention. In this naturalistic multicenter trial, we investigated its feasibility after 10 sessions ...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Sabaß L,Padberg F,Normann C,Engel V,Konrad C,Helmle K,Jobst A,Worlitz A,Brakemeier EL

更新日期：2018-12-01 00:00:00

abstract：:Circadian rhythm disturbance is highly prevalent in attention deficit hyperactivity disorder (ADHD). Recently, the association between the CLOCK gene and ADHD has been demonstrated in clinical samples, and the CLOCK gene's role was thought to be mediated by rhythm dysregulation. Meanwhile, ADHD has been suggested as t...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Jeong SH,Yu JC,Lee CH,Choi KS,Choi JE,Kim SH,Joo EJ

更新日期：2014-02-01 00:00:00

abstract：:Quality indicators are vital for monitoring the transformation of institution-based mental health services towards the provision of person-centered mental healthcare. While several mental healthcare quality indicators have been identified as relevant and valid, their actual usability and utility for routine monitoring...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Gaebel W,Lehmann I,Chisholm D,Hinkov H,Höschl C,Kapócs G,Kurimay T,Tosevski DL,Milosavljevic M,Nakov V,Winkler P,Zielasek J

更新日期：2020-04-08 00:00:00

abstract：:Deficits in task-related attentional engagement in attention-deficit/hyperactivity disorder (ADHD) have been hypothesised to be due to altered interrelationships between attention, default mode and salience networks. We examined the intrinsic connectivity during rest within and between these networks. Six-minute resti...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Sidlauskaite J,Sonuga-Barke E,Roeyers H,Wiersema JR

更新日期：2016-06-01 00:00:00