当前位置： SCI文献检索 > EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE期刊下所有文献 > Reexamination of the characteristics of the deficit schizophrenia patients.

Reexamination of the characteristics of the deficit schizophrenia patients.

Abstract：

:The aim of this study was to reexamine and compare the characteristics of the deficit and nondeficit schizophrenic patients. This cross-sectional study consisted of 62 in- and out-patients, 18-65 years of age, diagnosed with schizophrenia according to DSM-IV. The sociodemographic variables, premorbid adjustment, clinical course and general functioning level in the past five years were evaluated by utilizing the appropriate sections of Comprehensive Assessment of Symptoms and History (CASH). In addition, GAF, the Schedule for the Deficit Syndrome (SDS), Positive and Negative Syndrome Scale (PANSS), Montgomery Asberg Depression Scale (MADRS), the Neurological Evaluation Scale (NES) and the Simpson Angus Extrapyramidal Side Effects (EPS) Rating Scale, Trail A and B, Verbal Fluency, Stroop, Block Design and Finger Tapper tests were administered. Using the SDS, 19 patients (30.6 %) were categorized as deficit; 43 (69.4 %) were categorized as nondeficit. The deficit patients were worse on the Functioning During Past Five Years score of CASH. The PANSS and MADRS mean scores were not significantly different between the two groups, except a higher level of negative symptoms observed in the deficit group. NES scores were also significantly higher in the deficit group. However, sociodemographic and other clinical variables, neurocognitive measures and EPS symptoms did not show any significant difference between the two groups. Our findings suggest that the deficit schizophrenia is a distinct subgroup comprised of patients who have more negative symptoms, neurological impairment and poor functioning which may have a common underlying pathology.

journal_name

Eur Arch Psychiatry Clin Neurosci

journal_title

European archives of psychiatry and clinical neuroscience

authors

Tiryaki A,Yazici MK,Anil AE,Kabakçi E,Karaağaoğlu E,Göğüş A

doi

10.1007/s00406-003-0434-5

subject

Has Abstract

pub_date

2003-10-01 00:00:00

pages

221-7

issue

5

eissn

0940-1334

issn

1433-8491

journal_volume

253

pub_type

杂志文章

相关文献

EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE文献大全
  • Myoclonic epileptic seizures during clozapine treatment: a report of three cases.

    abstract：:Three adult schizophrenic patients without a previous history of epilepsy are reported who, during clozapine treatment, developed paroxysmal EEG patterns and generalized myoclonic jerks without alteration of consciousness. These seizures were phenomenologically identical to those occurring in juvenile myoclonic epilep...

    journal_title：European archives of psychiatry and clinical neuroscience

    pub_type： 杂志文章

    doi：10.1007/BF02279769

    authors： Gouzoulis E,Grunze H,von Bardeleben U

    更新日期：1991-01-01 00:00:00

  • Early traumatic life events, parental rearing styles, family history of mental disorders, and birth risk factors in patients with social anxiety disorder.

    abstract：OBJECTIVE:Childhood traumatic experiences, rearing styles, familial mental disorders and birth risk factors have been associated with the development of social anxiety disorder. METHOD:Patients with social anxiety disorder (n=50) and healthy controls (n=120) were investigated using a retrospective interview with 203 q...

    journal_title：European archives of psychiatry and clinical neuroscience

    pub_type： 杂志文章

    doi：10.1007/s00406-004-0521-2

    authors： Bandelow B,Charimo Torrente A,Wedekind D,Broocks A,Hajak G,Rüther E

    更新日期：2004-12-01 00:00:00

  • The work of Emil Kraepelin and his research group in München.

    abstract：:Emil Kraepelin is well known due to his development of the psychiatric classification. The ICD-10 and DSM-IV classification is based on the dichotomy of endogenous psychoses into affective psychoses and schizophrenia as early as 1899. Moreover, beside his classification system he put enormous impact on the development...

    journal_title：European archives of psychiatry and clinical neuroscience

    pub_type： 传,历史文章,杂志文章

    doi：10.1007/s00406-008-2001-6

    authors： Hippius H,Müller N

    更新日期：2008-06-01 00:00:00

  • Toward the delineation of mania subtypes in the French National EPIMAN-II Mille Cohort. Comparisons with prior cluster analytic investigations.

    abstract：BACKGROUND:Knowledge about psychopathologic presentations of mania in current clinical practice has to be refined in order to improve diagnosis and treatment. METHODS:One thousand ninety manic patients included in the French National Study EPIMAN-II Mille were submitted to a cluster analysis on the basis of multiple v...

    journal_title：European archives of psychiatry and clinical neuroscience

    pub_type： 杂志文章

    doi：10.1007/s00406-008-0823-x

    authors： Azorin JM,Kaladjian A,Adida M,Hantouche E,Hameg A,Lancrenon S,Akiskal HS

    更新日期：2008-12-01 00:00:00

  • Cerebral networks linked to the event-related potential P300.

    abstract：:P300 is an event-related potential that is elicited by an oddball paradigm. In several neuropsychiatric diseases, differences in latencies and amplitude compared to healthy subjects have been reported. Because of its clinical significance, several investigations have tried to elucidate the intracranial origins of the ...

    journal_title：European archives of psychiatry and clinical neuroscience

    pub_type： 杂志文章

    doi：10.1007/s00406-003-0419-4

    authors： Horn H,Syed N,Lanfermann H,Maurer K,Dierks T

    更新日期：2003-06-01 00:00:00

  • Kynurenine pathway and white matter microstructure in bipolar disorder.

    abstract：:Decreased availability of serotonin in the central nervous system has been suggested to be a central factor in the pathogenesis of depression. Activation of indoleamine 2-3 dioxygenase following a pro-inflammatory state could reduce the amount of tryptophan converted to serotonin and increase the production of tryptop...

    journal_title：European archives of psychiatry and clinical neuroscience

    pub_type： 杂志文章

    doi：10.1007/s00406-016-0731-4

    authors： Poletti S,Myint AM,Schüetze G,Bollettini I,Mazza E,Grillitsch D,Locatelli C,Schwarz M,Colombo C,Benedetti F

    更新日期：2018-03-01 00:00:00

  • Brainstem raphe lesion in patients with major depressive disorder and in patients with suicidal ideation recorded on transcranial sonography.

    abstract：:Recent transcranial sonography (TCS) studies showed that disruption of echogenic midbrain line, corresponding to basal limbic system and raphe nuclei (RN) within, might represent functional marker for the development of depression. Major depressive disorder (MDD) is one of the most common psychiatric disorders associa...

    journal_title：European archives of psychiatry and clinical neuroscience

    pub_type： 杂志文章

    doi：10.1007/s00406-009-0043-z

    authors： Budisic M,Karlovic D,Trkanjec Z,Lovrencic-Huzjan A,Vukovic V,Bosnjak J,Demarin V

    更新日期：2010-04-01 00:00:00

  • Prevention of rehospitalization in schizophrenia: results of an integrated care project in Germany.

    abstract：:The goal of this study was to prevent rehospitalizations and thus to optimize satisfaction with treatment and quality of life in patients suffering by schizophrenia or schizoaffective disorder. A complex intervention with improved cooperation between in- and outpatient services was applied to 46 "high utilizing" patie...

    journal_title：European archives of psychiatry and clinical neuroscience

    pub_type： 临床试验,杂志文章

    doi：10.1007/s00406-009-0056-7

    authors： Schmidt-Kraepelin C,Janssen B,Gaebel W

    更新日期：2009-11-01 00:00:00

  • Markers from event-related potential subcomponents and reaction time for information processing dysfunction in schizophrenia.

    abstract：:Event-related potentials (ERPs) can serve as markers for cognitive processing stages. Identification of those ERPs altered in schizophrenia offer information about cognitive dysfunction. Auditory evoked potentials (AEPs) were elicited within an oddball paradigm in 35 schizophrenic patients and compared with 35 healthy...

    journal_title：European archives of psychiatry and clinical neuroscience

    pub_type： 临床试验,杂志文章

    doi：10.1007/s004060050055

    authors： Frodl T,Meisenzahl EM,Gallinat J,Hegerl U,Möller HJ

    更新日期：1998-01-01 00:00:00

  • Avoidance behaviour: a predictor of the efficacy of pharmacotherapy in panic disorder?

    abstract：:The impact of the avoidance behaviour on the psychopharmacological treatment of panic disorder was explored in the Cross National Collaborative Panic Study (n = 1134 patients); in this double blind randomized trial alprazolam, imipramine and placebo were compared during an 8-week treatment period. Patients with extens...

    journal_title：European archives of psychiatry and clinical neuroscience

    pub_type： 临床试验,杂志文章,多中心研究,随机对照试验

    doi：10.1007/BF02219714

    authors： Maier W,Roth SM,Argyle N,Buller R,Lavori P,Brandon S,Benkert O

    更新日期：1991-01-01 00:00:00

  • Psychiatric morbidity among repatriated Greek migrants in a rural area.

    abstract：:This paper reports on psychiatric case identification by the application of the Structured Clinical Interview for DSM-III-R (SCID) in a sample of 198 Greek migrants repatriated from western europe in a northwestern province of Greece. The current (1 month) prevalence of psychiatric morbidity, based on the total number...

    journal_title：European archives of psychiatry and clinical neuroscience

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1007/BF02191542

    authors： Bilanakis N,Madianos MG,Liakos A

    更新日期：1995-01-01 00:00:00

  • Overactive performance monitoring in obsessive-compulsive disorder is independent of symptom expression.

    abstract：:Overactive performance monitoring has been consistently reported in obsessive-compulsive disorder (OCD). OCD is a clinically heterogeneous disorder and is characterized by several symptom dimensions that may have partially distinct neural correlates. We examined whether performance-monitoring alterations are related t...

    journal_title：European archives of psychiatry and clinical neuroscience

    pub_type： 杂志文章

    doi：10.1007/s00406-014-0499-3

    authors： Riesel A,Kathmann N,Endrass T

    更新日期：2014-12-01 00:00:00

  • Expressed and perceived emotion over time: does the patients' view matter for the caregivers' burden?

    abstract：:While the impact of mentally ill patients' perceptions of their key relatives' expressed emotion is well examined with regard to relapse, there is a paucity of evidence concerning the impact on their key relatives' burden. The present study aims to evaluate the relative prognostic value of expressed and perceived emot...

    journal_title：European archives of psychiatry and clinical neuroscience

    pub_type： 杂志文章

    doi：10.1007/s00406-010-0178-y

    authors： Möller-Leimkühler AM,Jandl M

    更新日期：2011-08-01 00:00:00

  • Binocular rivalry transitions predict inattention symptom severity in adult ADHD.

    abstract：:Attention deficit and hyperactivity disorder (ADHD) is a prevalent childhood disorder that is often maintained throughout the development and persists into adulthood. Established etiology models suggest that deficient inhibition underlies the core ADHD symptoms. While experimental evidence for impaired motor inhibitio...

    journal_title：European archives of psychiatry and clinical neuroscience

    pub_type： 杂志文章

    doi：10.1007/s00406-017-0790-1

    authors： Jusyte A,Zaretskaya N,Höhnle NM,Bartels A,Schönenberg M

    更新日期：2018-06-01 00:00:00

  • Remifentanil in electroconvulsive therapy: a systematic review and meta-analysis of randomized controlled trials.

    abstract：:In electroconvulsive therapy (ECT), remifentanil is often used concurrently with anesthetics. The objective of this study was to provide an up-to-date and comprehensive review on how the addition of remifentanil to anesthetics affects seizure duration and circulatory dynamics in mECT. We performed a meta-analysis of R...

    journal_title：European archives of psychiatry and clinical neuroscience

    pub_type： 杂志文章,meta分析,评审

    doi：10.1007/s00406-016-0670-0

    authors： Takekita Y,Suwa T,Sunada N,Kawashima H,Fabbri C,Kato M,Tajika A,Kinoshita T,Furukawa TA,Serretti A

    更新日期：2016-12-01 00:00:00

  • Non-neuroleptic approaches to treating negative symptoms in schizophrenia.

    abstract：:The novel/atypical neuroleptics have proven to be effective in treating negative symptoms but although clinical experience appears to show that they have advantages over the traditional neuroleptics in treating negative symptoms, superiority has not always been statistically confirmed and the treatment results in indi...

    journal_title：European archives of psychiatry and clinical neuroscience

    pub_type： 杂志文章,评审

    doi：10.1007/s00406-004-0503-4

    authors： Möller HJ

    更新日期：2004-04-01 00:00:00

  • Family aggregation of mental disorders in the nationwide Danish three generation study.

    abstract：OBJECTIVE:The study of familial aggregation of major mental disorders in a national population. METHOD:Within a Danish register-based cohort study, aggregation of mental disorders was analysed in all case-probands with first psychiatric contact before the age of 19 years in the time period between 1 April 1969 and 29 ...

    journal_title：European archives of psychiatry and clinical neuroscience

    pub_type： 杂志文章

    doi：10.1007/s00406-008-0865-0

    authors： Steinhausen HC,Foldager L,Perto G,Munk-Jørgensen P

    更新日期：2009-08-01 00:00:00

  • Neurocognitive performance in first-episode and chronic schizophrenic patients.

    abstract：:Previous research on neuropsychological disturbances in first-episode and chronic schizophrenic patients has provided mixed results which can be partially attributed to methodological inconsistencies. For the present study, 70 schizophrenic patients (40 with chronic and 30 with first-episode schizophrenia) were compar...

    journal_title：European archives of psychiatry and clinical neuroscience

    pub_type： 杂志文章

    doi：10.1007/s004060200006

    authors： Moritz S,Andresen B,Perro C,Schickel M,Krausz M,Naber D,PERSIST Study Group.

    更新日期：2002-02-01 00:00:00

  • Anxiogenic properties of yohimbine. I. Behavioral, physiological and biochemical measures.

    abstract：:The anxiogenic effects of yohimbine, a specific alpha-2-receptor antagonist were examined by administering 20 mg yohimbine orally to 8 panic patients on placebo treatment, 7 panic patients on alprazolam treatment and 12 controls using a double-blind randomized design, instructions that minimized the expectancy of expe...

    journal_title：European archives of psychiatry and clinical neuroscience

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1007/BF02191958

    authors： Albus M,Zahn TP,Breier A

    更新日期：1992-01-01 00:00:00

  • Prospective long-term follow-up of depressed patients with and without suicide attempts.

    abstract：:This 4-6-year prospective follow-up study compared reactive depressives with (n = 48) and without suicide attempts before index admission (n = 24). Both groups showed a favourable course and outcome concerning psychiatric diagnoses (DSM-III), psychopathology, social integration, and social functioning as well as displ...

    journal_title：European archives of psychiatry and clinical neuroscience

    pub_type： 杂志文章

    doi：10.1007/BF02190337

    authors： Bronisch T,Hecht H

    更新日期：1992-01-01 00:00:00

  • Homeless people at disadvantage in mental health services.

    abstract：OBJECTIVE:The aims of this study are threefold: to depict characteristics of homeless at discharge from a psychiatric hospital; to describe the utilisation of inpatient care and treatment measures during hospitalisation; and to analyse to what extent psychiatric disorders and clinical variables contribute to the risk f...

    journal_title：European archives of psychiatry and clinical neuroscience

    pub_type： 杂志文章

    doi：10.1007/s00406-005-0616-4

    authors： Lauber C,Lay B,Rössler W

    更新日期：2006-04-01 00:00:00

  • Psychiatric comorbidity and functional impairment in a clinically referred sample of adults with attention-deficit/hyperactivity disorder (ADHD).

    abstract：OBJECTIVE:This exploratory study aims to compare lifetime psychiatric axis-I-comorbidity and psychosocial functioning in a clinically referred sample of adult patients with attention-deficit/hyperactivity disorder (ADHD) with a population-based healthy control group and to examine whether patients with ADHD and lifetim...

    journal_title：European archives of psychiatry and clinical neuroscience

    pub_type： 杂志文章

    doi：10.1007/s00406-007-0712-8

    authors： Sobanski E,Brüggemann D,Alm B,Kern S,Deschner M,Schubert T,Philipsen A,Rietschel M

    更新日期：2007-10-01 00:00:00

  • Intoxicated persons showing challenging behavior demand complexity interventions: a pilot study at the interface of the ER and the complexity intervention unit.

    abstract：:Intoxicated persons showing challenging behavior (IPCBs) under influence of alcohol and/or drugs frequently have trouble finding appropriate acute care. Often IPCBs are stigmatized being unwilling or unable to accept help. Separated physical and mental healthcare systems hamper integrated acute care for IPCBs. This pi...

    journal_title：European archives of psychiatry and clinical neuroscience

    pub_type： 杂志文章

    doi：10.1007/s00406-020-01162-7

    authors： Verheesen SMH,Ten Doesschate F,van Schijndel MA,van der Gaag RJ,Cahn W,van Waarde JA

    更新日期：2020-07-12 00:00:00

  • Moclobemide and fluoxetine for panic disorder. International Panic Disorder Study Group.

    abstract：:An international, multicentre, double blind parallel group study compared the tolerability and efficacy of moclobemide with the selective serotonin reuptake inhibitor (SSRI) fluoxetine for panic disorder. SSRIs have been shown effective for panic. The target dose of moclobemide was 450 mg and of fluoxetine was 20 mg. ...

    journal_title：European archives of psychiatry and clinical neuroscience

    pub_type： 临床试验,杂志文章,多中心研究,随机对照试验

    doi：10.1007/pl00014164

    authors： Tiller JW,Bouwer C,Behnke K

    更新日期：1999-01-01 00:00:00

  • The deficit syndrome of the psychotic illness. A clinical and nosological study.

    abstract：:The deficit syndrome is thought to be specific to and a subtype of schizophrenia; however, there are scarce or no data on the prevalence and characteristics of this syndrome in non-schizophrenic psychoses. The aim of this study was to explore the prevalence and correlates of different types of negative symptoms (NegS)...

    journal_title：European archives of psychiatry and clinical neuroscience

    pub_type： 杂志文章

    doi：10.1007/s00406-004-0464-7

    authors： Peralta V,Cuesta MJ

    更新日期：2004-06-01 00:00:00

  • The epidemiology of functional psychoses of late onset.

    abstract：:For the functional psychoses of late life, epidemiological information comes from two sources: studies of persons who have reached psychiatric services; and surveys of elderly persons sampled from the general population. A conspectus of published data from both sources leads to the following conclusions: States phenom...

    journal_title：European archives of psychiatry and clinical neuroscience

    pub_type： 杂志文章,评审

    doi：10.1007/BF02900214

    authors： Henderson AS,Kay DW

    更新日期：1997-01-01 00:00:00

  • Association between psychopathology and problems of psychosocial functioning in the long-term outcome of patients diagnosed with schizophrenic, schizoaffective and affective disorders.

    abstract：:Mental health problems do significantly impact on a person's functioning. In the past, problems with psychosocial functioning were mainly associated with the diagnoses of schizophrenia. However, nowadays it is clear that impaired psychosocial functioning is also a common phenomenon in people suffering from affective d...

    journal_title：European archives of psychiatry and clinical neuroscience

    pub_type： 杂志文章

    doi：10.1007/s00406-012-0335-6

    authors： Bottlender R,Strauss A,Möller HJ

    更新日期：2013-03-01 00:00:00

  • Varenicline for smoking cessation in people with schizophrenia: systematic review and meta-analysis.

    abstract：:We performed an updated meta-analysis of randomized double-blind placebo-controlled trials (RCTs) on the effects of varenicline adjuvant therapy for smoking cessation in people with schizophrenia, on the basis of a previous meta-analysis (Tsoi in Cochrane Database Syst Rev 2:CD007253, 2013). We searched PubMed, the Co...

    journal_title：European archives of psychiatry and clinical neuroscience

    pub_type： 杂志文章,meta分析,评审

    doi：10.1007/s00406-014-0551-3

    authors： Kishi T,Iwata N

    更新日期：2015-04-01 00:00:00

  • Higher BDNF plasma levels are associated with a normalization of memory dysfunctions during an antidepressant treatment.

    abstract：:One important symptom of patients with major depressive disorder (MDD) is memory dysfunction. However, little is known about the relationship between memory performance and depression severity, about the course of memory performance during antidepressant treatment as well as about the relationship between memory perfo...

    journal_title：European archives of psychiatry and clinical neuroscience

    pub_type： 杂志文章

    doi：10.1007/s00406-019-01006-z

    authors： Engelmann J,Wagner S,Wollschläger D,Kaaden S,Schlicht KF,Dreimüller N,Braus DF,Müller MB,Tüscher O,Frieling H,Tadić A,Lieb K

    更新日期：2020-03-01 00:00:00

  • Postural imbalance: an early sign in HIV-1 infected patients.

    abstract：:We have recorded postural performance in 50 HIV-infected patients in different stages of the disease (Walter Reed (WR) stages I-VI) by means of a force measuring platform. The results were compared with 50 age-matched controls. A significant instability was particularly evident when standing on an unstable foot suppor...

    journal_title：European archives of psychiatry and clinical neuroscience

    pub_type： 杂志文章

    doi：10.1007/BF02195975

    authors： Trenkwalder C,Straube A,Paulus W,Krafczyk S,Schielke E,Einhäupl KM

    更新日期：1992-01-01 00:00:00