Neurocognitive performance in first-episode and chronic schizophrenic patients.

abstract：:Cannabinoid 1 receptor and glutamatergic dysfunction have both been implicated in the pathophysiology of schizophrenia. However, it remains unclear if cannabinoid 1 receptor alterations shown in drug-naïve/free patients with first episode psychosis may be linked to glutamatergic alterations in the illness. We aimed to...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Borgan F,Veronese M,Reis Marques T,Lythgoe DJ,Howes O

更新日期：2020-09-28 00:00:00

abstract：:The aim of the study was to report on the clinical utility of naturalistic adjunctive treatment with valproate (VPA) in a group of panic disorder (PD) patients with comorbid bipolar disorder (BD) or otherwise resistant to antidepressants. The hypothesis was that these patients might not respond because of coexisting l...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Perugi G,Frare F,Toni C,Tusini G,Vannucchi G,Akiskal HS

更新日期：2010-10-01 00:00:00

abstract：:An involvement of the central serotonergic system has constantly been reported in the pathogenesis of suicide. The dorsal raphe nucleus (DRN) is the main source of serotonergic innervation of forebrain limbic structures disturbed in suicidal behaviour, in which an abnormal microglia reaction seems to play a role. In o...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Brisch R,Steiner J,Mawrin C,Krzyżanowska M,Jankowski Z,Gos T

更新日期：2017-08-01 00:00:00

abstract：:The novel coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The escalating number of SARS-CoV-2-infected individuals has conferred the viral spread with the status of global pandemic. However, there are no prophylactic or therapeutic drugs available on the m...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Hashimoto K

更新日期：2021-01-05 00:00:00

abstract：:Mutations in the presenilin-1 gene (PS-1 gene) on chromosome 14 have recently been identified as a cause of familial early-onset Alzheimer's disease (EOAD). To our knowledge, only two German EOAD patients with mutations in the PS-1 gene have been identified thus far. Herein we report the case of a German EOAD patient ...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Hüll M,Fiebich BL,Dykierek P,Schmidtke K,Nitzsche E,Orszagh M,Deuschl G,Moser E,Schumacher M,Lücking C,Berger M,Bauer J

更新日期：1998-01-01 00:00:00

abstract：:This study investigates the nosological specificity and time stability of reduced facial expressivity in schizophrenia by means of objective measurement. Facial expression in an emotional interview was evaluated using the "Facial Action Coding System" in 33 acute schizophrenia patients and 23 acute depressive patients...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Gaebel W,Wölwer W

更新日期：2004-10-01 00:00:00

abstract：:Three adult schizophrenic patients without a previous history of epilepsy are reported who, during clozapine treatment, developed paroxysmal EEG patterns and generalized myoclonic jerks without alteration of consciousness. These seizures were phenomenologically identical to those occurring in juvenile myoclonic epilep...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Gouzoulis E,Grunze H,von Bardeleben U

更新日期：1991-01-01 00:00:00

abstract：:Altered neuroplasticity contributes to the pathophysiology of schizophrenia. However, the idea that antipsychotics may act, at least in part, by normalizing neurogenesis has not been consistently supported. Our study seeks to determine whether hippocampal cell proliferation is altered in adult rats pretreated with ket...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Keilhoff G,Grecksch G,Bernstein HG,Roskoden T,Becker A

更新日期：2010-03-01 00:00:00

abstract：:Negative symptoms were examined in 150 primarily first-admission patients diagnosed with schizophrenia, schizoaffective disorder, psychotic depression, psychotic bipolar disorder, and 'other' psychoses. The analysis focused on patients who were rated on the Scale for the Assessment of Negative Symptoms (SANS) within 4...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Fennig S,Bromet EJ,Galambos N,Putnam K

更新日期：1996-01-01 00:00:00

abstract：:Antisocial personality disorder is characterized by a stable, lifelong pattern of disregard for and violation of others' rights. Disruptions in the representation of fairness norms may represent a key mechanism in the development and maintenance of this disorder. Here, we investigated fairness norm considerations and ...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Mayer SV,Rauss K,Pourtois G,Jusyte A,Schönenberg M

更新日期：2019-09-01 00:00:00

abstract：:Our previous study has found that a long duration of untreated prodromal symptoms (DUPrS) does not increase the conversion risk to psychosis in individuals with attenuated psychosis syndrome (APS). However, whether a long DUPrS will lead to other poor outcomes remains unknown. The purpose of this study was to analyse ...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Zhang T,Xu L,Tang Y,Cui H,Tang X,Wei Y,Wang Y,Hu Q,Qian Z,Liu X,Li C,Wang J

更新日期：2019-12-01 00:00:00

abstract：:The alpha 1C subunit of the L-type voltage-gated calcium channel (CACNA1C) gene is one of the best replicated susceptibility loci for bipolar disorder, schizophrenia and major depression. It is involved in learning, memory and brain plasticity. Genetic studies using functional magnetic resonance imaging (fMRI) reporte...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Krug A,Witt SH,Backes H,Dietsche B,Nieratschker V,Shah NJ,Nöthen MM,Rietschel M,Kircher T

更新日期：2014-03-01 00:00:00

abstract：:The Neuregulin (NRG1) gene has been associated with schizophrenia, but its functional implications are largely unknown. Our aim was to assess differential brain activation between patients carrying an at-risk allele on the Neuregulin 1 gene and patients without this genetic risk. Neural signal changes between 14 first...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Kircher T,Thienel R,Wagner M,Reske M,Habel U,Kellermann T,Frommann I,Schwab S,Wölwer W,von Wilmsdorf M,Braus DF,Schmitt A,Rapp A,Stöcker T,Shah NJ,Henn FA,Sauer H,Gaebel W,Maier W,Schneider F

更新日期：2009-03-01 00:00:00

abstract：:Protein expression of VGF (nonacronymic) is induced by nerve/brain-derived growth factor, neurotrophin 3, and insulin. VGF is synthesized by neurons in the paraventricular (PVN) and supraoptic (SON) nuclei of the hypothalamus. After enzymatic processing, smaller VGF-derived peptides are secreted into the cerebrospinal...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Busse S,Bernstein HG,Busse M,Bielau H,Brisch R,Mawrin C,Müller S,Sarnyai Z,Gos T,Bogerts B,Steiner J

更新日期：2012-08-01 00:00:00

abstract：AIM:This study examined the extent to which fathers' and infants' interaction behavior were related to children's externalizing behavior problems at age 8 and 11 years. METHODS:In a prospective longitudinal study of children at risk for later psychopathology, 72 fathers and their 3-month-old children were videotaped a...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Trautmann-Villalba P,Gschwendt M,Schmidt MH,Laucht M

更新日期：2006-09-01 00:00:00

abstract：:The transcription nuclear factor-erythroid factor 2-related factor 2 (Nrf2) plays a key role in inflammation that is involved in depression. We previously reported that Nrf2 knock-out (KO) mice exhibit depression-like phenotypes through systemic inflammation. (R)-ketamine, an enantiomer of ketamine, has rapid-acting a...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Qu Y,Shan J,Wang S,Chang L,Pu Y,Wang X,Tan Y,Yamamoto M,Hashimoto K

更新日期：2020-11-12 00:00:00

abstract：:3H-Imipramine binding in relation to serotonergic function was studied in patients hospitalized following a suicide attempt. Comparison with a control group showed a highly significant difference in Bmax values. The results suggest, at least a posteriori, a biological alteration as the basis of suicidal behaviour. Alt...

journal_title：European archives of psychiatry and clinical neuroscience

authors： De Leo D,Caneva A,Marazziti D,Conti L

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND:Although a number of studies have reported on the association between obsessional personality features as measured by the Munich Personality Test (MPT) "Rigidity" scale and depression, there has been no examination of these relationships in a non-clinical sample. METHODS:The dimensional scores on the MPT we...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Sakado K,Sakado M,Seki T,Kuwabara H,Kojima M,Sato T,Someya T

更新日期：2001-06-01 00:00:00

abstract：OBJECTIVE:The prevalence and consequences of co-morbid axis-I and axis-II disorders as well as personality traits were examined in a large cohort of adult attention-deficit/hyperactivity disorder (AADHD) at a tertiary referral center. METHODS:In- and outpatients referred for diagnostic assessment of AADHD were screene...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Jacob CP,Romanos J,Dempfle A,Heine M,Windemuth-Kieselbach C,Kruse A,Reif A,Walitza S,Romanos M,Strobel A,Brocke B,Schäfer H,Schmidtke A,Böning J,Lesch KP

更新日期：2007-09-01 00:00:00

abstract：:The description of the heterogeneous phenomenological, pathophysiological, and etiological nature of schizophrenia is under way; however, the relationships between heterogeneity levels are still unclear. We performed a robust cross-sectional study, including a systematic neuropsychological battery, assessment of clini...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Szendi I,Racsmány M,Cimmer C,Csifcsák G,Kovács ZA,Szekeres G,Galsi G,Tóth F,Nagy A,Garab EA,Boda K,Gulyás G,Kiss JG,Dombi J,Pléh C,Janka Z

更新日期：2010-04-01 00:00:00

abstract：:Smooth-pursuit eye-tracking performance was examined in 100 schizophrenic patients and various control groups under both attention-enhancing and attention-distracting conditions. The level of attentional demand was varied by introducing a secondary reaction time task that directed attention either toward or away from ...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Schlenker R,Cohen R,Berg P,Hubman W,Mohr F,Watzl H,Werther P

更新日期：1994-01-01 00:00:00

abstract：:Some studies suggest seasonality of suicide attempts in females, but not in males. The reasons for this gender difference remain unclear. Only few studies addressed the question whether gender differences in seasonality of suicide attempts reflect gender differences in the choice of method for suicide attempts, with i...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Mergl R,Havers I,Althaus D,Rihmer Z,Schmidtke A,Lehfeld H,Niklewski G,Hegerl U

更新日期：2010-08-01 00:00:00

abstract：:To improve recognition and treatment of depression in primary care it would be advantageous to have criteria for identification of later depression. Only a few studies were performed on primary care samples to examine risk factors for new depressive episodes. These were mostly cross-sectional and did not include psych...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Barkow K,Heun R,Ustün TB,Maier W

更新日期：2001-01-01 00:00:00

abstract：OBJECTIVE:The aims of this study are threefold: to depict characteristics of homeless at discharge from a psychiatric hospital; to describe the utilisation of inpatient care and treatment measures during hospitalisation; and to analyse to what extent psychiatric disorders and clinical variables contribute to the risk f...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Lauber C,Lay B,Rössler W

更新日期：2006-04-01 00:00:00

abstract：UNLABELLED:Patients with somatoform pain often complain of sleep disorders, but sleep disorders are not an integrated part of the diagnosis of this disorder. Restless legs syndrome is associated with painful symptoms and sleep disturbances. The aim of our study was to evaluate the prevalence of restless legs syndrome (...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Aigner M,Prause W,Freidl M,Weiss M,Izadi S,Bach M,Saletu B

更新日期：2007-02-01 00:00:00

abstract：OBJECTIVES:The present study aims to assess the factor structure of the DSM-IV Premenstrual Dysphoric Disorder (PMDD) symptoms and its relationship with depressive symptoms. METHODS:We evaluated retrospectively PMDD symptoms in 513 female college students, through a self-reporting questionnaire based on DSM-IV criteri...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Teng CT,Filho AH,Artes R,Gorenstein C,Andrade LH,Wang YP

更新日期：2005-02-01 00:00:00

abstract：:Physical activity is a common adjunctive therapy in psychiatric and psychosomatic hospitals. In the present study, we assessed the effects of an exercise program, integrated into routine inpatient treatment, on cognitive performance and subjective severity of depression in a sample of patients suffering from major dep...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Buschert V,Prochazka D,Bartl H,Diemer J,Malchow B,Zwanzger P,Brunnauer A

更新日期：2019-08-01 00:00:00

abstract：:Depressive disorders are influenced by a complex interplay between genetic and environmental factors. Multiple studies support a role of serotonergic pathways in the pathophysiology of depressive disorders. As a rate-limiting enzyme of serotonin synthesis in the brain, tryptophan hydroxylase 2 (TPH2) represents a plau...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Van der Auwera S,Janowitz D,Schulz A,Homuth G,Nauck M,Völzke H,Rose M,Meyer zu Schwabedissen H,Freyberger HJ,Grabe HJ

更新日期：2014-11-01 00:00:00

abstract：:Attention deficit and hyperactivity disorder (ADHD) is a prevalent childhood disorder that is often maintained throughout the development and persists into adulthood. Established etiology models suggest that deficient inhibition underlies the core ADHD symptoms. While experimental evidence for impaired motor inhibitio...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Jusyte A,Zaretskaya N,Höhnle NM,Bartels A,Schönenberg M

更新日期：2018-06-01 00:00:00

abstract：:Cerebrospinal fluid acetylcholinesterase (CSF AChE) was determined for elderly delirious patients during the acute stage and after a 1- and 4-year follow-up periods, and the AChE levels were compared with age-equivalent controls. The AChE levels measured during the index admission correlated with the length of life af...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Koponen HJ,Sirviö J,Lepola U,Leinonen E,Riekkinen PJ

更新日期：1994-01-01 00:00:00