Non-neuroleptic approaches to treating negative symptoms in schizophrenia.

abstract：OBJECTIVE:The study of familial aggregation of major mental disorders in a national population. METHOD:Within a Danish register-based cohort study, aggregation of mental disorders was analysed in all case-probands with first psychiatric contact before the age of 19 years in the time period between 1 April 1969 and 29 ...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Steinhausen HC,Foldager L,Perto G,Munk-Jørgensen P

更新日期：2009-08-01 00:00:00

abstract：:The aim of this study was to evaluate tardive dyskinesia (TD) (prevalence and possible risk factors, pharmacological and clinical), in a population of schizophrenic patients after prolonged institutionalization. A total of 148 patients (80 male, 68 female) aged between 28 and 87 years (mean 55, SD 11) diagnosed accord...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Altamura AC,Cavallaro R,Regazzetti MG

更新日期：1990-01-01 00:00:00

abstract：:Dopamine D(2) blocking typical antipsychotic drugs are known to change the cerebral perfusion patterns of schizophrenic patients, especially in the frontal cortex and basal ganglia. In recent years atypical antipsychotics such as olanzapine, which have high serotonin 5-HT(2A)/dopamine D(2) occupation ratios, have been...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Gonul AS,Kula M,Sofuoglu S,Tutus A,Esel E

更新日期：2003-02-01 00:00:00

abstract：:Mental health problems do significantly impact on a person's functioning. In the past, problems with psychosocial functioning were mainly associated with the diagnoses of schizophrenia. However, nowadays it is clear that impaired psychosocial functioning is also a common phenomenon in people suffering from affective d...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Bottlender R,Strauss A,Möller HJ

更新日期：2013-03-01 00:00:00

abstract：:Event-related potentials (ERPs) can serve as markers for cognitive processing stages. Identification of those ERPs altered in schizophrenia offer information about cognitive dysfunction. Auditory evoked potentials (AEPs) were elicited within an oddball paradigm in 35 schizophrenic patients and compared with 35 healthy...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Frodl T,Meisenzahl EM,Gallinat J,Hegerl U,Möller HJ

更新日期：1998-01-01 00:00:00

abstract：:MAOA and, to a lesser extent, MAOB polymorphisms have been related to aggression traits and suicidality. We aimed to investigate the role of MAOA and MAOB in suicidal versus non-suicidal participants and interactions between genetic variation and suicidal status on aggression and anger-related traits. The sample was c...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Antypa N,Giegling I,Calati R,Schneider B,Hartmann AM,Friedl M,Konte B,Lia L,De Ronchi D,Serretti A,Rujescu D

更新日期：2013-08-01 00:00:00

abstract：:Schizophrenia is a severe neuropsychiatric disorder with familial loading as heritable risk factor and cannabis abuse as the most relevant environmental risk factor up to date. Cannabis abuse has been related to an earlier onset of the disease and persisting cannabis consumption is associated with reduced symptom impr...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Malchow B,Hasan A,Schneider-Axmann T,Jatzko A,Gruber O,Schmitt A,Falkai P,Wobrock T

更新日期：2013-11-01 00:00:00

abstract：:This paper reports on psychiatric case identification by the application of the Structured Clinical Interview for DSM-III-R (SCID) in a sample of 198 Greek migrants repatriated from western europe in a northwestern province of Greece. The current (1 month) prevalence of psychiatric morbidity, based on the total number...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Bilanakis N,Madianos MG,Liakos A

更新日期：1995-01-01 00:00:00

abstract：:Savoxepine, an atypical neuroleptic compound developed in the 1980s, was believed to act via selective limbic dopamine D(2)-receptor blockade. The results of the presented double-blind, randomised, controlled clinical trial comparing savoxepine (n = 58) with haloperidol (n = 29) did not confirm the preclinical data su...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Volz HP,Möller HJ,Gerebtzoff A,Bischoff S

更新日期：2002-04-01 00:00:00

abstract：:Accelerated repetitive transcranial magnetic stimulation (rTMS) protocols are being increasingly studied because of their potential to provide quicker and enhanced treatment efficacy. However, there is a lack of accelerated deep TMS with H1-coil (adTMS) treatment research. This randomized pilot study investigated the ...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Filipčić I,Šimunović Filipčić I,Sučić S,Milovac Ž,Gereš N,Matić K,Čelić-Ružić M,Zečević Penić S,Orgulan I,Požgaj V,Bajić Ž

更新日期：2020-05-24 00:00:00

abstract：:Obesity is highly prevalent worldwide and results in a high disease burden. The efforts to monitor and predict treatment outcome in participants with obesity using functional magnetic resonance imaging (fMRI) depends on the reliability of the investigated task-fMRI brain activation. To date, no study has investigated ...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Bach P,Grosshans M,Koopmann A,Kienle P,Vassilev G,Otto M,Bumb JM,Kiefer F

更新日期：2020-12-17 00:00:00

abstract：:Obsessive-compulsive symptoms (OCS) are frequently reported in patients with schizophrenia and have been associated with subjective distress and higher impairment. Recent studies suggest fluctuation in co-occurring OCS and associations with the course of psychotic symptoms. Current evidence is limited by few studies w...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Schirmbeck F,Konijn M,Hoetjes V,Zink M,de Haan L,For Genetic Risk and Outcome of Psychosis (GROUP).

更新日期：2019-03-01 00:00:00

abstract：:A group of 52 patients presenting at an outpatient unit for anxiety disorders were included consecutively in a prospective 2-year follow-up study. Patients were administered to a structured interview for DSM-III-R diagnoses, a follow-up interview (LIFE), and various other ratings. Sociodemographic and illness-history ...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Scheibe G,Albus M

更新日期：1994-01-01 00:00:00

abstract：:Early life maltreatment (ELM) has long-lasting effects on social interaction. When interacting with their own child, women with ELM often report difficulties in parenting and show reduced maternal sensitivity. Sensitive maternal behavior requires the recognition of the child's emotional state depicted in its facial em...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Neukel C,Herpertz SC,Hinid-Attar C,Zietlow AL,Fuchs A,Moehler E,Bermpohl F,Bertsch K

更新日期：2019-03-01 00:00:00

abstract：:The objective of this study is to determine whether cannabis influences BDNF levels in patients with psychosis (FEP) and healthy volunteers (HV) to help understand the role of BDNF in psychosis. We assessed the association between BDNF and cannabis in a cohort of FEP antipsychotic-naïve patients and HV, whilst control...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Toll A,Bergé D,Burling K,Scoriels L,Treen D,Monserrat C,Marmol F,Duran X,Jones PB,Pérez-Solà V,Fernandez-Egea E,Mané A

更新日期：2020-10-01 00:00:00

abstract：:Schizophrenia has been linked to disturbed connectivity between large-scale brain networks. Altered thalamocortical connectivity might be a major mechanism mediating regionally distributed dysfunction, yet it is only incompletely understood. We analysed functional magnetic resonance imaging data obtained during restin...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Klingner CM,Langbein K,Dietzek M,Smesny S,Witte OW,Sauer H,Nenadic I

更新日期：2014-03-01 00:00:00

abstract：:Our previous study has found that a long duration of untreated prodromal symptoms (DUPrS) does not increase the conversion risk to psychosis in individuals with attenuated psychosis syndrome (APS). However, whether a long DUPrS will lead to other poor outcomes remains unknown. The purpose of this study was to analyse ...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Zhang T,Xu L,Tang Y,Cui H,Tang X,Wei Y,Wang Y,Hu Q,Qian Z,Liu X,Li C,Wang J

更新日期：2019-12-01 00:00:00

abstract：:Astrocytes are the most numerous cell type within the central nervous system. Early during development they act as guiding structures for migratory neurons; later they are not only the main source for nutrients and growth factors in the brain, but they are also communication partners of neighboring neurons. For this p...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Kirchhoff F,Dringen R,Giaume C

更新日期：2001-08-01 00:00:00

abstract：:The aim of this study was to reexamine and compare the characteristics of the deficit and nondeficit schizophrenic patients. This cross-sectional study consisted of 62 in- and out-patients, 18-65 years of age, diagnosed with schizophrenia according to DSM-IV. The sociodemographic variables, premorbid adjustment, clini...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Tiryaki A,Yazici MK,Anil AE,Kabakçi E,Karaağaoğlu E,Göğüş A

更新日期：2003-10-01 00:00:00

abstract：:The diagnosis of muscle cramp is based on clinical features. Algorithms are presented for the diagnosis of muscle cramp and cramp syndromes. ...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Jansen PH,Joosten EM,Vingerhoets HM

更新日期：1991-01-01 00:00:00

abstract：:Emil Kraepelin is well known due to his development of the psychiatric classification. The ICD-10 and DSM-IV classification is based on the dichotomy of endogenous psychoses into affective psychoses and schizophrenia as early as 1899. Moreover, beside his classification system he put enormous impact on the development...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Hippius H,Müller N

更新日期：2008-06-01 00:00:00

abstract：:Evidence suggests that the anterior cingulate cortex (ACC) plays a key role in the development of posttraumatic stress disorder (PTSD). Owing to the region's highly variable patterns, three different studies of PTSD have yielded inconsistent volume reductions. Accordingly, in order to measure the correct borders and v...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Jatzko A,Vogler C,Demirakca T,Ruf M,Malchow B,Falkai P,Braus DF,Ende G,Schmitt A

更新日期：2013-10-01 00:00:00

abstract：:Bipolar disorder (BD) has been associated with a proinflammatory state in which TNF-α seems to play a relevant role. The aim of the present study was to evaluate the plasma levels of TNF-α and its soluble receptors (sTNFR1 and sTNFR2) in BD patients in mania and euthymia in comparison with control subjects. We evaluat...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Barbosa IG,Huguet RB,Mendonça VA,Sousa LP,Neves FS,Bauer ME,Teixeira AL

更新日期：2011-03-01 00:00:00

abstract：:Despite the lack of clinical data about the role of the endocannabinoid system (ECS) in affective disorders, preclinical work suggests that the ECS is relevant in both with regard to the etiology of depression as well as the mediation of antidepressant effects. We measured the intraindividual levels of the endocannabi...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Kranaster L,Hoyer C,Aksay SS,Bumb JM,Leweke FM,Janke C,Thiel M,Lutz B,Bindila L,Sartorius A

更新日期：2017-12-01 00:00:00

abstract：:Decreased availability of serotonin in the central nervous system has been suggested to be a central factor in the pathogenesis of depression. Activation of indoleamine 2-3 dioxygenase following a pro-inflammatory state could reduce the amount of tryptophan converted to serotonin and increase the production of tryptop...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Poletti S,Myint AM,Schüetze G,Bollettini I,Mazza E,Grillitsch D,Locatelli C,Schwarz M,Colombo C,Benedetti F

更新日期：2018-03-01 00:00:00

abstract：:We performed an updated meta-analysis of randomized double-blind placebo-controlled trials (RCTs) on the effects of varenicline adjuvant therapy for smoking cessation in people with schizophrenia, on the basis of a previous meta-analysis (Tsoi in Cochrane Database Syst Rev 2:CD007253, 2013). We searched PubMed, the Co...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Kishi T,Iwata N

更新日期：2015-04-01 00:00:00

abstract：:Auditory verbal hallucinations (AH) are core symptoms of schizophrenia. They are often severely distressing and refractory to therapy. Their perception is associated with increased activity in temporoparietal areas of the brain. Repetitive transcranial magnetic stimulation (rTMS) can reduce focal brain hyperactivity a...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Plewnia C,Brendel B,Schwippel T,Martus P,Cordes J,Hasan A,Fallgatter AJ

更新日期：2018-10-01 00:00:00

abstract：:Intravascular lymphomatosis (IVL), a rare type of non-Hodgkin's lymphoma, is an uncommon cause of progressive dementia, usually followed by death within a few months of onset of clinical disease. Often this aggressive tumor is only diagnosed at autopsy, because of misleading clinical features mimicking a broad spectru...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Albrecht R,Krebs B,Reusche E,Nagel M,Lencer R,Kretzschmar HA

更新日期：2005-08-01 00:00:00

abstract：:Posttraumatic stress disorder (PTSD) has been associated with an altered processing of threat-related stimuli. In particular, an attentional bias towards threat cues has been consistently found in behavioral studies. However, it is unclear whether increased attention towards threat cues translates into preferential pr...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Catani C,Adenauer H,Keil J,Aichinger H,Neuner F

更新日期：2009-09-01 00:00:00

abstract：OBJECTIVE:Childhood traumatic experiences, rearing styles, familial mental disorders and birth risk factors have been associated with the development of social anxiety disorder. METHOD:Patients with social anxiety disorder (n=50) and healthy controls (n=120) were investigated using a retrospective interview with 203 q...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Bandelow B,Charimo Torrente A,Wedekind D,Broocks A,Hajak G,Rüther E

更新日期：2004-12-01 00:00:00